I bought this product starting in September of 2015. I have ALWAYS struggled with acne since I was 14. I have never gone a day without acne and I always had 1-4 cystic acne that was deep, huge and painful at all times. I thought it was something I always had to live with. I had PCOS and borderline hypothyroid so I started taking iodine, zinc and selenium. All three helped my thyroid. I believe the iodine helped cure my PCOS as I now get my menstrual cycle like clock work and last ultrasound found no more cysts on my ovaries!! The zinc helped my acne somewhat especially the cystic ones but I still was getting pimples and felt hopeless that I would have acne till Menopause. I started taking this B complex and immediately my pimples were gone!! I mean gone!!!! I was finally acne free for the first time in 16 years. After a month in a half I stopped taking the complex as I got pregnant and wanted to make sure it was safe to take. After 1-2 weeks acne came back. It wasn't until I started the GOL B complex again that acne is gone again. This stuff works. I think it is the B5 in it. I love that it is so effective at lower doses then the synthetic kind. I have tried B complex before without improvements In my acne. If you have acne give this a try. I also believe the zinc is helpful too