Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
USERS' SCORE
Good
Based on 7 Reviews
8.3
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Iron (from Ionic Plant Based Minerals)
2 mg
10%
HSO Probiotic Blend (5 Billion CFU)¹Saccharomyces boulardii, Organic Barley Grass², Organic Oat Grass², Lactobacillus plantarum, Bacillus subtilis, Bifidobacterium lactis, Bifidobacterium bifidum, Lactobacillus rhamnosus, Bifidobacterium breve, Lactobacillus casei, Lactobacillus salivarius, Lactobacillus acidophilus, Lactobacillus brevis, Bifidobacterium longum, Lactobacillus paracasei
410 mg
+
Ionic Plant Based Minerals
290 mg
+
Top Medical Research Studies
8
Positive effects on gastrointestinal symptoms
Our research aimed to understand how a specific symbiotic gel, containing Lactobacillus acidophilus, affects gastrointestinal symptoms, including heartburn, in hemodialysis patients.
We conducted a double-blinded, placebo-controlled trial with 42 participants over two months. The group receiving the symbiotic gel reported significant improvements in the frequency and severity of symptoms like heartburn and stomachache compared to the control group.
Overall, the gel appeared safe with no adverse effects noted. More extensive studies are needed, but these findings suggest promising benefits for managing heartburn in dialysis patients.
We conducted a double-blinded, placebo-controlled trial with 42 participants over two months. The group receiving the symbiotic gel reported significant improvements in the frequency and severity of symptoms like heartburn and stomachache compared to the control group.
Overall, the gel appeared safe with no adverse effects noted. More extensive studies are needed, but these findings suggest promising benefits for managing heartburn in dialysis patients.
Read More
7
We examined whether probiotics could ease gastrointestinal (GI) discomforts after gastric bypass surgery. In a double-blind, randomized study, 60 patients were assigned to receive either Bifidobacterium longum, another probiotic, or digestive enzymes. After just two weeks, everyone saw notable improvements in their quality of life. Specifically, symptoms like heartburn, gas, and abdominal bloating lessened significantly. While this is promising, the long-term benefits of probiotics in managing GI episodes post-surgery remain to be fully understood.
Read More
8
Food supplement enhances heartburn relief
We evaluated a food supplement that contained the probiotic Lactobacillus acidophilus, along with peptides and multivitamins, to see if it could help relieve heartburn in people with mild-to-moderate gastroesophageal reflux disease (GERD).
In a well-structured, randomized, double-blind, placebo-controlled study, 56 adults took either the supplement or a placebo for 28 days.
Results showed that those taking the supplement experienced a significant decrease in heartburn frequency and severity, along with a drop in over-the-counter medication use. Overall, participants reported improvements in their quality of life compared to those on placebo.
In a well-structured, randomized, double-blind, placebo-controlled study, 56 adults took either the supplement or a placebo for 28 days.
Results showed that those taking the supplement experienced a significant decrease in heartburn frequency and severity, along with a drop in over-the-counter medication use. Overall, participants reported improvements in their quality of life compared to those on placebo.
Read More
Most Useful Reviews
10
Acid reflux healed
12 people found this helpful
Simply the best! After trying numerous probiotics without any noticeable results, Garden of Life’s Primal Defense Ultra proved effective. I took three capsules daily for three weeks, and I’m pleased to say my acid reflux is completely healed! I recommend this product wholeheartedly, and even after reducing my dosage, I haven't had any heartburn.
Read More
10
No heartburn relief
5 people found this helpful
No more heartburn, no more constipation. Amazing. Truly. If one a day does not suffice, try two, then three. This is exactly what our bodies need.
Read More
10
Consistent relief
Haven't had heartburn since I started using these regularly.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.7
- All Researches
8
Food supplement enhances heartburn relief
We evaluated a food supplement that contained the probiotic Lactobacillus acidophilus, along with peptides and multivitamins, to see if it could help relieve heartburn in people with mild-to-moderate gastroesophageal reflux disease (GERD).
In a well-structured, randomized, double-blind, placebo-controlled study, 56 adults took either the supplement or a placebo for 28 days.
Results showed that those taking the supplement experienced a significant decrease in heartburn frequency and severity, along with a drop in over-the-counter medication use. Overall, participants reported improvements in their quality of life compared to those on placebo.
In a well-structured, randomized, double-blind, placebo-controlled study, 56 adults took either the supplement or a placebo for 28 days.
Results showed that those taking the supplement experienced a significant decrease in heartburn frequency and severity, along with a drop in over-the-counter medication use. Overall, participants reported improvements in their quality of life compared to those on placebo.
Read More
8
Positive effects on gastrointestinal symptoms
Our research aimed to understand how a specific symbiotic gel, containing Lactobacillus acidophilus, affects gastrointestinal symptoms, including heartburn, in hemodialysis patients.
We conducted a double-blinded, placebo-controlled trial with 42 participants over two months. The group receiving the symbiotic gel reported significant improvements in the frequency and severity of symptoms like heartburn and stomachache compared to the control group.
Overall, the gel appeared safe with no adverse effects noted. More extensive studies are needed, but these findings suggest promising benefits for managing heartburn in dialysis patients.
We conducted a double-blinded, placebo-controlled trial with 42 participants over two months. The group receiving the symbiotic gel reported significant improvements in the frequency and severity of symptoms like heartburn and stomachache compared to the control group.
Overall, the gel appeared safe with no adverse effects noted. More extensive studies are needed, but these findings suggest promising benefits for managing heartburn in dialysis patients.
Read More
7
We examined whether probiotics could ease gastrointestinal (GI) discomforts after gastric bypass surgery. In a double-blind, randomized study, 60 patients were assigned to receive either Bifidobacterium longum, another probiotic, or digestive enzymes. After just two weeks, everyone saw notable improvements in their quality of life. Specifically, symptoms like heartburn, gas, and abdominal bloating lessened significantly. While this is promising, the long-term benefits of probiotics in managing GI episodes post-surgery remain to be fully understood.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
10
Acid reflux healed
12 people found this helpful
Simply the best! After trying numerous probiotics without any noticeable results, Garden of Life’s Primal Defense Ultra proved effective. I took three capsules daily for three weeks, and I’m pleased to say my acid reflux is completely healed! I recommend this product wholeheartedly, and even after reducing my dosage, I haven't had any heartburn.
Read More
10
No heartburn relief
5 people found this helpful
No more heartburn, no more constipation. Amazing. Truly. If one a day does not suffice, try two, then three. This is exactly what our bodies need.
Read More
10
Consistent relief
Haven't had heartburn since I started using these regularly.
Read More
10
Ultimate effectiveness
My doctor recommended this product, and I take it daily throughout the year. I found it excellent. My parents use it as well. I used to suffer occasional stomach upset or heartburn, but since starting Primal Defense, all that has vanished. While overseas, my friend forgot her IBS medication and felt unwell. I offered her Primal Defense, and she took two capsules each day, experiencing no further problems from the first day.
Read More
7.5
Heartburn subsided
13 people found this helpful
Glad I stuck it out! Initially, I experienced horrendous heartburn and stopped using this probiotic. However, after reading about the gut's healing process, I tried again and persevered. After about five days, the heartburn subsided, and I no longer experience discomfort. I take it with food, which I find helpful, and my belly bloat has diminished.
Read More
Frequently Asked Questions
10
Consistent relief
Haven't had heartburn since I started using these regularly.
10
Ultimate effectiveness
My doctor recommended this product, and I take it daily throughout the year. I found it excellent. My parents use it as well. I used to suffer occasional stomach upset or heartburn, but since starting Primal Defense, all that has vanished. While overseas, my friend forgot her IBS medication and felt unwell. I offered her Primal Defense, and she took two capsules each day, experiencing no further problems from the first day.
10
No heartburn relief
5 people found this helpful
No more heartburn, no more constipation. Amazing. Truly. If one a day does not suffice, try two, then three. This is exactly what our bodies need.
8
Food supplement enhances heartburn relief
We evaluated a food supplement that contained the probiotic Lactobacillus acidophilus, along with peptides and multivitamins, to see if it could help relieve heartburn in people with mild-to-moderate gastroesophageal reflux disease (GERD).
In a well-structured, randomized, double-blind, placebo-controlled study, 56 adults took either the supplement or a placebo for 28 days.
Results showed that those taking the supplement experienced a significant decrease in heartburn frequency and severity, along with a drop in over-the-counter medication use. Overall, participants reported improvements in their quality of life compared to those on placebo.
In a well-structured, randomized, double-blind, placebo-controlled study, 56 adults took either the supplement or a placebo for 28 days.
Results showed that those taking the supplement experienced a significant decrease in heartburn frequency and severity, along with a drop in over-the-counter medication use. Overall, participants reported improvements in their quality of life compared to those on placebo.
8
Positive effects on gastrointestinal symptoms
Our research aimed to understand how a specific symbiotic gel, containing Lactobacillus acidophilus, affects gastrointestinal symptoms, including heartburn, in hemodialysis patients.
We conducted a double-blinded, placebo-controlled trial with 42 participants over two months. The group receiving the symbiotic gel reported significant improvements in the frequency and severity of symptoms like heartburn and stomachache compared to the control group.
Overall, the gel appeared safe with no adverse effects noted. More extensive studies are needed, but these findings suggest promising benefits for managing heartburn in dialysis patients.
We conducted a double-blinded, placebo-controlled trial with 42 participants over two months. The group receiving the symbiotic gel reported significant improvements in the frequency and severity of symptoms like heartburn and stomachache compared to the control group.
Overall, the gel appeared safe with no adverse effects noted. More extensive studies are needed, but these findings suggest promising benefits for managing heartburn in dialysis patients.
7
We examined whether probiotics could ease gastrointestinal (GI) discomforts after gastric bypass surgery. In a double-blind, randomized study, 60 patients were assigned to receive either Bifidobacterium longum, another probiotic, or digestive enzymes. After just two weeks, everyone saw notable improvements in their quality of life. Specifically, symptoms like heartburn, gas, and abdominal bloating lessened significantly. While this is promising, the long-term benefits of probiotics in managing GI episodes post-surgery remain to be fully understood.
References
- Tursi F, Benedetto E, Spina A, De Ponti I, Amone F, et al. Efficacy of a Food Supplement Containing LA14, Peptides, and a Multivitamin Complex in Improving Gastroesophageal Reflux Disease-Related Outcomes and Quality of Life of Subjects Showing Mild-to-Moderate Gastroesophageal Reflux Disease. Nutrients. 2024;16. doi:10.3390/nu16111759
- Viramontes-Hörner D, Márquez-Sandoval F, Martín-del-Campo F, Vizmanos-Lamotte B, Sandoval-Rodríguez A, et al. Effect of a symbiotic gel (Lactobacillus acidophilus + Bifidobacterium lactis + inulin) on presence and severity of gastrointestinal symptoms in hemodialysis patients. J Ren Nutr. 2015;25:284. doi:10.1053/j.jrn.2014.09.008
- Chen JC, Lee WJ, Tsou JJ, Liu TP, Tsai PL. Effect of probiotics on postoperative quality of gastric bypass surgeries: a prospective randomized trial. Surg Obes Relat Dis. 2016;12:57. doi:10.1016/j.soard.2015.07.010
