Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.8
USERS' SCORE
Good
Based on 8 Reviews
8.7
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Iron (from Ionic Plant Based Minerals)
2 mg
10%
HSO Probiotic Blend (5 Billion CFU)¹Saccharomyces boulardii, Organic Barley Grass², Organic Oat Grass², Lactobacillus plantarum, Bacillus subtilis, Bifidobacterium lactis, Bifidobacterium bifidum, Lactobacillus rhamnosus, Bifidobacterium breve, Lactobacillus casei, Lactobacillus salivarius, Lactobacillus acidophilus, Lactobacillus brevis, Bifidobacterium longum, Lactobacillus paracasei
410 mg
+
Ionic Plant Based Minerals
290 mg
+
Top Medical Research Studies
8
We explored the effects of Lactobacillus species on bile-induced DNA damage in esophageal cells, which occurs during gastroesophageal reflux disease (GERD). By exposing these bacteria to a bile-rich environment, we found they could survive and interact beneficially with injured cells.
Notably, adding Lactobacillus after bile injury boosted the repair of DNA damage and lessened inflammation. This suggests that these probiotics could play a role in protecting against long-term complications of GERD, like Barrett's esophagus and esophageal cancer.
Notably, adding Lactobacillus after bile injury boosted the repair of DNA damage and lessened inflammation. This suggests that these probiotics could play a role in protecting against long-term complications of GERD, like Barrett's esophagus and esophageal cancer.
Read More
9
Probiotic supplement alleviates GERD symptoms
We investigated the impact of a dietary supplement containing lactobacillus acidophilus, bioactive peptides, and vitamins on individuals with mild-to-moderate gastroesophageal reflux disease (GERD). Conducted as a randomized, double-blind, placebo-controlled study, we followed fifty-six adults over 28 days.
Participants reported a significant reduction in heartburn frequency and severity with the active supplement compared to the placebo. They also noted a decreased reliance on over-the-counter medications and improved quality of life. Overall, this supplement appears to bring meaningful relief to those struggling with GERD symptoms.
Participants reported a significant reduction in heartburn frequency and severity with the active supplement compared to the placebo. They also noted a decreased reliance on over-the-counter medications and improved quality of life. Overall, this supplement appears to bring meaningful relief to those struggling with GERD symptoms.
Read More
8
We examined the effects of Bifidobacterium lactis as a complementary treatment for reflux esophagitis (RE) in a randomized, double-blind, placebo-controlled study. A total of 110 RE patients received rabeprazole while being supplemented with either Bifidobacterium or a placebo over 8 weeks.
Our findings showed that the probiotic group experienced quicker symptom relief and a longer time before symptoms returned, compared to the placebo. We also noted improvements in gut microbiota diversity following the treatment. Thus, Bifidobacterium lactis appears to provide significant benefits as an adjunct therapy for managing reflux symptoms.
Our findings showed that the probiotic group experienced quicker symptom relief and a longer time before symptoms returned, compared to the placebo. We also noted improvements in gut microbiota diversity following the treatment. Thus, Bifidobacterium lactis appears to provide significant benefits as an adjunct therapy for managing reflux symptoms.
Read More
Most Useful Reviews
10
Normal bowel movements
27 people found this helpful
Amazing stuff! After suffering from constant diarrhea for nearly a decade and being diagnosed with IBS, I started taking this probiotic based on a friend's recommendation. It worked wonders! I no longer have acid reflux, have regained normal bowel movements, and feel energetic now.
Read More
10
Completely healed reflux
12 people found this helpful
I’ve tried numerous probiotics without noticeable effects, but Garden of Life's Primal Defense Ultra has made a remarkable difference. By taking it correctly, my acid reflux is entirely healed! No heartburn or reflux since starting, and I happily recommend it.
Read More
9
Game changer for reflux
6 people found this helpful
I got rid of my acid reflux! This product truly helped my stomach issues. I often experienced reflux due to anxiety. After hearing about this on YouTube, I purchased it, and it's a game changer for me!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.8
- All Researches
9
Probiotic supplement alleviates GERD symptoms
We investigated the impact of a dietary supplement containing lactobacillus acidophilus, bioactive peptides, and vitamins on individuals with mild-to-moderate gastroesophageal reflux disease (GERD). Conducted as a randomized, double-blind, placebo-controlled study, we followed fifty-six adults over 28 days.
Participants reported a significant reduction in heartburn frequency and severity with the active supplement compared to the placebo. They also noted a decreased reliance on over-the-counter medications and improved quality of life. Overall, this supplement appears to bring meaningful relief to those struggling with GERD symptoms.
Participants reported a significant reduction in heartburn frequency and severity with the active supplement compared to the placebo. They also noted a decreased reliance on over-the-counter medications and improved quality of life. Overall, this supplement appears to bring meaningful relief to those struggling with GERD symptoms.
Read More
9
We aimed to explore the effectiveness of a specific probiotic mixture called Ecologic®Relief in treating constipation among pregnant women. Over four weeks, participants reported significant improvements in their bowel habits, including increased defecation frequency and reduced sensations of obstruction and incomplete evacuation.
Importantly, we noted that the probiotic mixture also seemed to decrease reflux episodes from 60% to 20%. This suggests that not only does Ecologic®Relief help with constipation, but it may also provide relief from reflux symptoms during pregnancy. We believe more extensive studies will be beneficial to confirm these findings.
Importantly, we noted that the probiotic mixture also seemed to decrease reflux episodes from 60% to 20%. This suggests that not only does Ecologic®Relief help with constipation, but it may also provide relief from reflux symptoms during pregnancy. We believe more extensive studies will be beneficial to confirm these findings.
Read More
8
We explored the effects of Lactobacillus species on bile-induced DNA damage in esophageal cells, which occurs during gastroesophageal reflux disease (GERD). By exposing these bacteria to a bile-rich environment, we found they could survive and interact beneficially with injured cells.
Notably, adding Lactobacillus after bile injury boosted the repair of DNA damage and lessened inflammation. This suggests that these probiotics could play a role in protecting against long-term complications of GERD, like Barrett's esophagus and esophageal cancer.
Notably, adding Lactobacillus after bile injury boosted the repair of DNA damage and lessened inflammation. This suggests that these probiotics could play a role in protecting against long-term complications of GERD, like Barrett's esophagus and esophageal cancer.
Read More
8
We examined the effects of Bifidobacterium lactis as a complementary treatment for reflux esophagitis (RE) in a randomized, double-blind, placebo-controlled study. A total of 110 RE patients received rabeprazole while being supplemented with either Bifidobacterium or a placebo over 8 weeks.
Our findings showed that the probiotic group experienced quicker symptom relief and a longer time before symptoms returned, compared to the placebo. We also noted improvements in gut microbiota diversity following the treatment. Thus, Bifidobacterium lactis appears to provide significant benefits as an adjunct therapy for managing reflux symptoms.
Our findings showed that the probiotic group experienced quicker symptom relief and a longer time before symptoms returned, compared to the placebo. We also noted improvements in gut microbiota diversity following the treatment. Thus, Bifidobacterium lactis appears to provide significant benefits as an adjunct therapy for managing reflux symptoms.
Read More
8
In our exploration, we examined how Bifidobacterium lactis HN019 could influence gut transit time and gastrointestinal symptoms. We enrolled 100 adults with functional GI issues, splitting them into groups to receive either high-dose, low-dose, or placebo for two weeks.
We found that both treatment groups experienced significant reductions in gut transit times and a decrease in various GI symptoms. The placebo group did not show any notable improvements.
Overall, B. lactis HN019 seems effective in easing reflux-related symptoms and improving gut health.
We found that both treatment groups experienced significant reductions in gut transit times and a decrease in various GI symptoms. The placebo group did not show any notable improvements.
Overall, B. lactis HN019 seems effective in easing reflux-related symptoms and improving gut health.
Read More
User Reviews
USERS' SCORE
Good
Based on 8 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
10
Normal bowel movements
27 people found this helpful
Amazing stuff! After suffering from constant diarrhea for nearly a decade and being diagnosed with IBS, I started taking this probiotic based on a friend's recommendation. It worked wonders! I no longer have acid reflux, have regained normal bowel movements, and feel energetic now.
Read More
10
Completely healed reflux
12 people found this helpful
I’ve tried numerous probiotics without noticeable effects, but Garden of Life's Primal Defense Ultra has made a remarkable difference. By taking it correctly, my acid reflux is entirely healed! No heartburn or reflux since starting, and I happily recommend it.
Read More
9
Game changer for reflux
6 people found this helpful
I got rid of my acid reflux! This product truly helped my stomach issues. I often experienced reflux due to anxiety. After hearing about this on YouTube, I purchased it, and it's a game changer for me!
Read More
9
Significant improvement
2 people found this helpful
Excellent product; it is a bit pricey, but certainly worth it 100%. I felt much better after my reflux gastritis and dysbacteriosis.
Read More
9
Effective solution
1 people found this helpful
A very effective product. My stomach acid reflux issue has been resolved before I finished the large bottle.
Read More
Frequently Asked Questions
9
Effective solution
1 people found this helpful
A very effective product. My stomach acid reflux issue has been resolved before I finished the large bottle.
7.5
Superior results
This has helped significantly with my IBS and acid reflux. I've tried many probiotics, but nothing has worked as effectively as this brand for my gut. The ingredients and quality are excellent.
9
Significant improvement
2 people found this helpful
Excellent product; it is a bit pricey, but certainly worth it 100%. I felt much better after my reflux gastritis and dysbacteriosis.
9
Probiotic supplement alleviates GERD symptoms
We investigated the impact of a dietary supplement containing lactobacillus acidophilus, bioactive peptides, and vitamins on individuals with mild-to-moderate gastroesophageal reflux disease (GERD). Conducted as a randomized, double-blind, placebo-controlled study, we followed fifty-six adults over 28 days.
Participants reported a significant reduction in heartburn frequency and severity with the active supplement compared to the placebo. They also noted a decreased reliance on over-the-counter medications and improved quality of life. Overall, this supplement appears to bring meaningful relief to those struggling with GERD symptoms.
Participants reported a significant reduction in heartburn frequency and severity with the active supplement compared to the placebo. They also noted a decreased reliance on over-the-counter medications and improved quality of life. Overall, this supplement appears to bring meaningful relief to those struggling with GERD symptoms.
8
We examined the effects of Bifidobacterium lactis as a complementary treatment for reflux esophagitis (RE) in a randomized, double-blind, placebo-controlled study. A total of 110 RE patients received rabeprazole while being supplemented with either Bifidobacterium or a placebo over 8 weeks.
Our findings showed that the probiotic group experienced quicker symptom relief and a longer time before symptoms returned, compared to the placebo. We also noted improvements in gut microbiota diversity following the treatment. Thus, Bifidobacterium lactis appears to provide significant benefits as an adjunct therapy for managing reflux symptoms.
Our findings showed that the probiotic group experienced quicker symptom relief and a longer time before symptoms returned, compared to the placebo. We also noted improvements in gut microbiota diversity following the treatment. Thus, Bifidobacterium lactis appears to provide significant benefits as an adjunct therapy for managing reflux symptoms.
References
- Tursi F, Benedetto E, Spina A, De Ponti I, Amone F, et al. Efficacy of a Food Supplement Containing LA14, Peptides, and a Multivitamin Complex in Improving Gastroesophageal Reflux Disease-Related Outcomes and Quality of Life of Subjects Showing Mild-to-Moderate Gastroesophageal Reflux Disease. Nutrients. 2024;16. doi:10.3390/nu16111759
- Bernard JN, Chinnaiyan V, Almeda J, Catala-Valentin A, Andl CD. sp. Facilitate the Repair of DNA Damage Caused by Bile-Induced Reactive Oxygen Species in Experimental Models of Gastroesophageal Reflux Disease. Antioxidants (Basel). 2023;12. doi:10.3390/antiox12071314
- Lee SJ, Lee JW. Probiotics prophylaxis in infants with primary vesicoureteral reflux. Pediatr Nephrol. 2015;30:609. doi:10.1007/s00467-014-2988-z
- Gan L, Wang Y, Huang S, Zheng L, Feng Q, et al. Therapeutic Evaluation of subsp. MH-02 as an Adjunctive Treatment in Patients with Reflux Esophagitis: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients. 2024;16. doi:10.3390/nu16030342
- de Milliano I, Tabbers MM, van der Post JA, Benninga MA. Is a multispecies probiotic mixture effective in constipation during pregnancy? 'A pilot study'. Nutr J. 2012;11:80. doi:10.1186/1475-2891-11-80
- Waller PA, Gopal PK, Leyer GJ, Ouwehand AC, Reifer C, et al. Dose-response effect of Bifidobacterium lactis HN019 on whole gut transit time and functional gastrointestinal symptoms in adults. Scand J Gastroenterol. 2011;46:1057. doi:10.3109/00365521.2011.584895
