Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 70 Researches
8
USERS' SCORE
Moderately Good
Based on 79 Reviews
7.3
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Proprietary Probiotic BlendLacticaseibacillus rhamnosus R0011Lactobacillus helvetius R0052Pediococcus acidilactici R1001Lacticaseibacillus casei R0215Bifidobacterium longum BB536Lactiplantibacillus plantarum R1012Bifidobacterium breve R0070Lactococcus lactis subsp. lactis R1058
131 mg (10 Billion CFU)

Top Medical Research Studies

9.5
Bifidobacterium lactis reduced diarrhea duration
We explored the impact of Bifidobacterium animalis subsp. lactis BLa80 on diarrhea in young children through a well-structured, randomized, double-blinded, placebo-controlled study.

Our findings show that children receiving the probiotic experienced a significantly shorter duration of diarrhea and a higher recovery rate compared to those given a placebo.

Notably, we also observed beneficial changes in gut microbiome composition and gene functions that promote immune response.

This evidence suggests that Bifidobacterium lactis can effectively support recovery from acute diarrhea in children.
Read More
9.5
Lactococcus lactis shows immunization potential
We explored the effectiveness of a live recombinant Lactococcus lactis vaccine designed to combat enterotoxigenic Escherichia coli, a major cause of diarrhea. The study involved administering the vaccine to mice, who then showed strong immune responses, such as increased antibody production and T cell activation.

After being challenged with ETEC, these mice exhibited complete protection from the disease. This suggests that the Lactococcus lactis vaccine could be a promising oral vaccine candidate against E. coli-related diarrhea.
Read More
9
Lactobacillus reduces diarrhea in children
We evaluated the effectiveness of Lactobacillus reuteri DSM 17938 as an addition to oral rehydration therapy for children suffering from acute gastroenteritis. This randomized, controlled trial took place in a pediatric emergency setting and included children aged 1 month to 5 years.

The results indicated that those treated with Lactobacillus experienced a notable reduction in the duration and frequency of diarrhea compared to those given a placebo. With a safe profile at high doses, this probiotic shows promise as a simple, low-risk solution to alleviate diarrhea in young patients.
Read More

Most Useful Reviews

9
Ease of stool passage
18 people found this helpful
Perfect compatibility! I experienced plenty of gas the first week, but I now have regular bowel movements every morning. My mother, who suffers from irritable bowel syndrome, has also had success with this product. I have ordered more, as it has genuinely helped both me and my mother.
Read More
10
Feeling much better
17 people found this helpful
Thank YOU! I had been feeling dreadful for months. Every time I ate, I experienced diarrhoea and constant stomach pain. After taking these for just one day, I feel significantly better. My stomach is no longer bloated, and I noticed a visible improvement in just one day. I'm so grateful I could cry. Thank you to everyone who posted reviews; they guided me to purchase these.
Read More
10
Perfect poops achieved
11 people found this helpful
This product instantly stopped my lifetime of diarrhoea! I took 6 pills daily instead of the recommended 2, and it provided me with perfect stools. I had no more wet poops, which was a relief, and even helped a friend with constipation. This product genuinely balances bowel issues. I must order more as my symptoms have slowly returned.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 70 Researches
8
  • All Researches
9.5
Lactobacillus improves H. pylori treatment
We examined the impact of Lactobacillus spp. on diarrhea related to Helicobacter pylori infections through a comprehensive analysis of 26 studies. Our findings suggest that using Lactobacillus significantly improves H. pylori eradication rates and reduces gastrointestinal side effects, including diarrhea.

Supplementation was particularly effective when paired with standard triple therapy, showing promising results, especially in children. This positions Lactobacillus as a valuable adjunct treatment option for managing these infections while reducing discomfort.
Read More
9.5
Probiotics improve H. pylori treatments
We analyzed various studies on incorporating probiotics into treatments for Helicobacter pylori (H. pylori) infection. Our findings revealed that adding probiotics like Bifidobacterium longum improved the eradication rate significantly.

Specifically, we noted that the probiotic group experienced fewer side effects, including diarrhea, nausea, and abdominal pain. This suggests that probiotics could not only enhance the effectiveness of H. pylori treatment but also make it more comfortable for patients. Overall, these results support the use of probiotics in gastric therapies.
Read More
9.5
Bifidobacterium longum shows promise
We conducted a randomized double-blind, placebo-controlled trial with 200 participants to see how well the probiotic CECT 7347 (ES1) and its heat-treated version (HT-ES1) could help those suffering from diarrhea-predominant irritable bowel syndrome (IBS-D). After 12 weeks of treatment, both ES1 and HT-ES1 showed significant improvements in symptom severity, with marked reductions in IBS-SSS scores compared to the placebo.

Secondary benefits included better stool consistency and quality of life, making these treatments promising options for managing IBS-D symptoms. These findings reflect meaningful advancements in probiotic and postbiotic solutions.
Read More
9.5
Bifidobacterium lactis reduced diarrhea duration
We explored the impact of Bifidobacterium animalis subsp. lactis BLa80 on diarrhea in young children through a well-structured, randomized, double-blinded, placebo-controlled study.

Our findings show that children receiving the probiotic experienced a significantly shorter duration of diarrhea and a higher recovery rate compared to those given a placebo.

Notably, we also observed beneficial changes in gut microbiome composition and gene functions that promote immune response.

This evidence suggests that Bifidobacterium lactis can effectively support recovery from acute diarrhea in children.
Read More
9.5
Lactococcus lactis shows immunization potential
We explored the effectiveness of a live recombinant Lactococcus lactis vaccine designed to combat enterotoxigenic Escherichia coli, a major cause of diarrhea. The study involved administering the vaccine to mice, who then showed strong immune responses, such as increased antibody production and T cell activation.

After being challenged with ETEC, these mice exhibited complete protection from the disease. This suggests that the Lactococcus lactis vaccine could be a promising oral vaccine candidate against E. coli-related diarrhea.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 79 Reviews
7.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Ease of stool passage
18 people found this helpful
Perfect compatibility! I experienced plenty of gas the first week, but I now have regular bowel movements every morning. My mother, who suffers from irritable bowel syndrome, has also had success with this product. I have ordered more, as it has genuinely helped both me and my mother.
Read More
10
Feeling much better
17 people found this helpful
Thank YOU! I had been feeling dreadful for months. Every time I ate, I experienced diarrhoea and constant stomach pain. After taking these for just one day, I feel significantly better. My stomach is no longer bloated, and I noticed a visible improvement in just one day. I'm so grateful I could cry. Thank you to everyone who posted reviews; they guided me to purchase these.
Read More
10
Perfect poops achieved
11 people found this helpful
This product instantly stopped my lifetime of diarrhoea! I took 6 pills daily instead of the recommended 2, and it provided me with perfect stools. I had no more wet poops, which was a relief, and even helped a friend with constipation. This product genuinely balances bowel issues. I must order more as my symptoms have slowly returned.
Read More
10
Chronic diarrhoea relief
8 people found this helpful
Chronic diarrhoea is no longer an issue for me thanks to this product!
Read More
9
Long-term diarrhoea improvement
8 people found this helpful
This has been effective and amazing! After long-term diarrhoea, I noticed immediate improvement.
Read More

Frequently Asked Questions

10
Diarrhoea stopped
1 people found this helpful
After experiencing up to five days of diarrhoea, I found this product to effectively stop my symptoms. I'm grateful for the relief!
10
Perfect poops achieved
11 people found this helpful
This product instantly stopped my lifetime of diarrhoea! I took 6 pills daily instead of the recommended 2, and it provided me with perfect stools. I had no more wet poops, which was a relief, and even helped a friend with constipation. This product genuinely balances bowel issues. I must order more as my symptoms have slowly returned.
9
Consistent bowel movements
3 people found this helpful
I've tried various probiotics without success, but this one finally made a difference. My bowel movements became regular and consistent, dramatically improving my diarrhoea. I recommend giving it a few weeks.
10
Digestive improvement
4 people found this helpful
After a month of antibiotics, I developed severe constipation and diarrhoea. Nothing worked until I tried Jarro-Dophilus EPS, which restored my digestion within a week. I'm grateful for this product.
10
Chronic diarrhoea relief
8 people found this helpful
Chronic diarrhoea is no longer an issue for me thanks to this product!
9
Ease of stool passage
18 people found this helpful
Perfect compatibility! I experienced plenty of gas the first week, but I now have regular bowel movements every morning. My mother, who suffers from irritable bowel syndrome, has also had success with this product. I have ordered more, as it has genuinely helped both me and my mother.
9
Restores digestion
4 people found this helpful
After being discharged from hospital post-Covid-19, I faced huge digestive problems. Following a nutritionist's advice, I took this probiotic and it restored my digestion. It helped alleviate diarrhoea after antibiotics.
9
Effective digestion aid
1 people found this helpful
I use probiotics from various manufacturers for my family. The Jarrow Formulas and California Gold Nutrition options offer the best performance and value. These capsules contain eight clinically tested strains and help regulate digestive function while boosting immunity. They work for constipation and diarrhea. The ability to add the powder to smoothies or make yogurt is a bonus. Our digestion and immunity have both noticeably improved since using them.
0
Major diarrhoea
6 people found this helpful
I wanted to like this product as I’ve heard many positive things, but it gave me major diarrhoea every time I took it. It didn't help my constipation either, so I won’t be buying it again.
0
Summer storage issues
2 people found this helpful
I believe this product may have deteriorated in the heat of summer, as I experienced diarrhea after taking it and had to consider proper storage conditions.
9
Probiotics reduce antibiotic-related diarrhea
We conducted a multi-hospital study to tackle the common issue of antibiotic-associated diarrhea (AAD). By comparing probiotics, specifically Lactobacillus rhamnosus GG and Bifidobacterium longum BB536, with a placebo among 340 adult patients, we aimed to find out if these friendly bacteria could help.

Our findings revealed that probiotics significantly lowered both the incidence and duration of AAD compared to the placebo group. Patients reported positive outcomes, indicating high adherence to the treatment as well.
9
Bifidobacterium Longum aids in diarrhea
We explored the impact of Bifidobacterium animalis sp. Lactis XLTG11 on acute diarrhea in children through a randomized, double-blinded, placebo-controlled study. Children received either conventional treatment plus the probiotic or conventional treatment alone.

Our findings revealed that the probiotic group experienced shorter diarrhea duration and hospital stays compared to the control group. Additionally, a greater percentage of these children showed improvement, along with significant changes in gut microbiome composition.

These results suggest that XLTG11 can effectively enhance treatment outcomes for diarrhea in children.
9
LRa05 probiotic helps reduce diarrhea
We investigated how the probiotic LRa05 affects acute watery diarrhea in young children. In a randomized controlled trial with 57 children receiving LRa05 and 54 on a placebo, we observed that those in the LRa05 group experienced a significantly shorter duration of diarrhea and improved fecal consistency.

These children also showed better gut microbiome changes. Specifically, more of them reported improvement compared to the placebo group. Overall, LRa05 proved to be a promising treatment option for easing diarrhea in children.
9
Lactobacillus reduces diarrhea in children
We evaluated the effectiveness of Lactobacillus reuteri DSM 17938 as an addition to oral rehydration therapy for children suffering from acute gastroenteritis. This randomized, controlled trial took place in a pediatric emergency setting and included children aged 1 month to 5 years.

The results indicated that those treated with Lactobacillus experienced a notable reduction in the duration and frequency of diarrhea compared to those given a placebo. With a safe profile at high doses, this probiotic shows promise as a simple, low-risk solution to alleviate diarrhea in young patients.
9
Probiotic improves diarrhea symptoms
We evaluated how well the probiotic Neobiotic Lactobalance®, containing Lactobacillus rhamnosus, helps relieve diarrhea linked to irritable bowel syndrome (IBS) and antibiotic-associated diarrhea (AAD).

In our study of 54 patients, we noted significant reductions in diarrhea severity and abdominal pain after 21 days of daily probiotic intake. For those with IBS, symptoms decreased nearly threefold, while AAD patients saw even greater improvements.

Additionally, microbiological analysis confirmed that the probiotic improved gut health by increasing beneficial bacteria. Overall, we found Neobiotic Lactobalance® effective in normalizing gut flora and alleviating diarrhea symptoms.
8
Probiotics may reduce pediatric diarrhea
We explored how probiotics, particularly Lactobacillus rhamnosus, might help prevent and treat antibiotic-associated diarrhea (AAD) in children. Our analysis included 20 systematic reviews and utilized various assessment tools to evaluate their quality.

While high doses of probiotics showed significant effects, we noticed concerns about the quality of reporting and evidence in many reviews. This means that, while the potential is there, cautious interpretation of results is necessary as further improvements in study methodology are needed.

References

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  13. Li S, Lu T, Lin Z, Zhang Y, Zhou X, et al. Supplementation with probiotics co-cultivation improves the reproductive performance in a sow-piglet model by mother-infant microbiota transmission and placental mTOR signaling. World J Microbiol Biotechnol. 2024;41:13. doi:10.1007/s11274-024-04222-5
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  18. Gwee KA, Lee WRW, Chua Q, Chiou FK, Aw MM, et al. The evidence for probiotics in the treatment of digestive disorders in the pediatric population. J Gastroenterol Hepatol. 2025;40:41. doi:10.1111/jgh.16809
  19. Shah J, Adnan SH, Yousaf MS, Din SJU, Haq MU, et al. A Multi-Hospital Comparative Study on the Efficacy of Probiotics Versus Placebo in Preventing Antibiotic-Associated Diarrhea in Adult Patients. Cureus. 2024;16:e70881. doi:10.7759/cureus.70881
  20. Shawky LM, Abo El Wafa SM, Behery M, Bahr MH, Abu Alnasr MT, et al. Lactobacillus rhamnosus GG and Tannic Acid Synergistically Promote the Gut Barrier Integrity in a Rat Model of Experimental Diarrhea via Selective Immunomodulatory Cytokine Targeting. Mol Nutr Food Res. 2024;68:e2400295. doi:10.1002/mnfr.202400295
  21. Anvarifard P, Anbari M, Ghalichi F, Ghoreishi Z, Zarezadeh M. The effectiveness of probiotics as an adjunct therapy in patients under mechanical ventilation: an umbrella systematic review and meta-analysis. Food Funct. 2024;15:5737. doi:10.1039/d3fo04653b
  22. Alharbi BF, Alateek AA. Investigating the influence of probiotics in preventing Traveler's diarrhea: Meta-analysis based systematic review. Travel Med Infect Dis. 2024;59:102703. doi:10.1016/j.tmaid.2024.102703
  23. Abdulah DM, Sulaiman SJ, Ahmed ZW. Effect of probiotics plus zinc supplementation on clinical outcomes of infants and children with acute infectious diarrhea: a randomized controlled trial. Clin Exp Pediatr. 2024;67:203. doi:10.3345/cep.2023.01340
  24. Waitzberg D, Guarner F, Hojsak I, Ianiro G, Polk DB, et al. Can the Evidence-Based Use of Probiotics (Notably Saccharomyces boulardii CNCM I-745 and Lactobacillus rhamnosus GG) Mitigate the Clinical Effects of Antibiotic-Associated Dysbiosis?. Adv Ther. 2024;41:901. doi:10.1007/s12325-024-02783-3
  25. Saviano A, Petruzziello C, Cancro C, Macerola N, Petti A, et al. The Efficacy of a Mix of Probiotics ( LMG P-27481 and GG ATCC 53103) in Preventing Antibiotic-Associated Diarrhea and Infection in Hospitalized Patients: Single-Center, Open-Label, Randomized Trial. Microorganisms. 2024;12. doi:10.3390/microorganisms12010198
  26. Poeta M, Cioffi V, Tarallo A, Damiano C, Lo Vecchio A, et al. Postbiotic Preparation of against Diarrhea and Oxidative Stress Induced by Spike Protein of SARS-CoV-2 in Human Enterocytes. Antioxidants (Basel). 2023;12. doi:10.3390/antiox12101878
  27. Drozdov VN, Shikh EV, Astapovskii AA, Khalaidzheva KN, Solovieva SA, et al. [Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with irritable bowel syndrome with diarrhea and antibiotic-associated diarrhea]. Vopr Pitan. 2023;92:92. doi:10.33029/0042-8833-2023-92-4-92-103
  28. Mego M, Danis R, Chovanec J, Jurisova S, Bystricky B, et al. Randomized double-blind, placebo-controlled multicenter phase III study of prevention of irinotecan-induced diarrhea by a probiotic mixture containing Bifidobacterium BB-12 LGG in colorectal cancer patients. Front Oncol. 2023;13:1168654. doi:10.3389/fonc.2023.1168654
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  32. Tanashat M, Abuelazm M, Abouzid M, Al-Ajlouni YA, Ramadan A, et al. Efficacy of probiotics regimens for Helicobacter pylori eradication: A systematic review, pairwise, and network meta-analysis of randomized controlled trials. Clin Nutr ESPEN. 2025;65:424. doi:10.1016/j.clnesp.2024.11.016
  33. Moreno-Muñoz JA, Ojeda JD, López JJ. A Probiotic Bacterium with Activity against the Most Frequent Bacteria and Viruses Causing Pediatric Diarrhea: subsp. CECT 7210 ( IM1). Microorganisms. 2024;12. doi:10.3390/microorganisms12061183
  34. Srivastava S, Basak U, Naghibi M, Vijayakumar V, Parihar R, et al. A randomized double-blind, placebo-controlled trial to evaluate the safety and efficacy of live CECT 7347 (ES1) and heat-treated CECT 7347 (HT-ES1) in participants with diarrhea-predominant irritable bowel syndrome. Gut Microbes. 2024;16:2338322. doi:10.1080/19490976.2024.2338322
  35. Lenoir M, Wienke J, Fardao-Beyler F, Roese N. An 8-Week Course of Bifidobacterium longum 35624 Is Associated with a Reduction in the Symptoms of Irritable Bowel Syndrome. Probiotics Antimicrob Proteins. 2025;17:315. doi:10.1007/s12602-023-10151-w
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  37. Li W, Zhang S, Wang Y, Bian H, Yu S, et al. Complex probiotics alleviate ampicillin-induced antibiotic-associated diarrhea in mice. Front Microbiol. 2023;14:1156058. doi:10.3389/fmicb.2023.1156058
  38. Mizutani Y, Kawamoto S, Takahashi M, Doi H, Wakida K, et al. Efficacy and Safety of Synbiotics in Patients Undergoing Autologous Hematopoietic Stem Cell Transplantation: A Randomized, Double-blinded, Placebo-controlled Pilot Study. Intern Med. 2023;62:2949. doi:10.2169/internalmedicine.1314-22
  39. Yalcin G, Demirbas F, Bacalan F, Toy EB. Evaluation of treatment in acute gastroenteritis: A comparative study. J Pak Med Assoc. 2022;72:2019. doi:10.47391/JPMA.4438
  40. Li W, Kai L, Jiang Z, He H, Yang M, et al. , and Reversed ETEC-Inducing Intestinal Inflammation in Mice. Microorganisms. 2022;10. doi:10.3390/microorganisms10122350
  41. Yakovenko EP, Strokova TV, Ivanov AN, Iakovenko AV, Gioeva IZ, et al. [The effectiveness of a probiotic containing Bifidobacterium longum BB-46 and Enterococcus faecium ENCfa-68 in the treatment of post-infectious irritable bowel syndrome. Prospective randomized comparative study]. Ter Arkh. 2022;94:180. doi:10.26442/00403660.2022.02.201368
  42. Shin SY, Park S, Moon JM, Kim K, Kim JW, et al. Compositional Changes in the Gut Microbiota of Responders and Non-responders to Probiotic Treatment Among Patients With Diarrhea-predominant Irritable Bowel Syndrome: A Post Hoc Analysis of a Randomized Clinical Trial. J Neurogastroenterol Motil. 2022;28:642. doi:10.5056/jnm21202
  43. Álvarez-Mercado AI, Plaza-Díaz J, de Almagro MC, Gil Á, Moreno-Muñoz JA, et al. subsp. CECT 7210 Reduces Inflammatory Cytokine Secretion in Caco-2 Cells Cultured in the Presence of CECT 515. Int J Mol Sci. 2022;23. doi:10.3390/ijms231810813
  44. Moreno-Muñoz JA, Martín-Palomas M, Jiménez López J. [Bifidobacterium longum subsp. infantis CECT 7210 (B. infantis IM-1®) shows activity against intestinal pathogens]. Nutr Hosp. 2022;39:65. doi:10.20960/nh.04315
  45. Uttarwar RG, Mekonnen SA, Van Beeck W, Wang A, Finnegan P, et al. Effects of Bifidobacterium animalis subsp. lactis BB-12 and yogurt on mice during oral antibiotic administration. Microbiol Res. 2024;286:127794. doi:10.1016/j.micres.2024.127794
  46. Jeong JJ, Jin YJ, Ganesan R, Park HJ, Min BH, et al. Multistrain Probiotics Alleviate Diarrhea by Modulating Microbiome-Derived Metabolites and Serotonin Pathway. Probiotics Antimicrob Proteins. 2024. doi:10.1007/s12602-024-10232-4
  47. Chen K, Jin S, Ma Y, Cai L, Xu P, et al. Adjudicative efficacy of Bifidobacterium animalis subsp. lactis BLa80 in treating acute diarrhea in children: a randomized, double-blinded, placebo-controlled study. Eur J Clin Nutr. 2024;78:501. doi:10.1038/s41430-024-01428-6
  48. Pang J, Liu Y, Kang L, Ye H, Zang J, et al. Bifidobacterium animalis Promotes the Growth of Weaning Piglets by Improving Intestinal Development, Enhancing Antioxidant Capacity, and Modulating Gut Microbiota. Appl Environ Microbiol. 2022;88:e0129622. doi:10.1128/aem.01296-22
  49. Şahin K, Şahintürk Y, Köker G, Özçelik Köker G, Bostan F, et al. Metformin with Versus without Concomitant Probiotic Therapy in Newly Diagnosed Patients with Type 2 Diabetes or Prediabetes: A Comparative Analysis in Relation to Glycemic Control, Gastrointestinal Side Effects, and Treatment Compliance. Turk J Gastroenterol. 2022;33:925. doi:10.5152/tjg.2022.211063
  50. Lukasik J, Dierikx T, Besseling-van der Vaart I, de Meij T, Szajewska H. Multispecies Probiotic for the Prevention of Antibiotic-Associated Diarrhea in Children: A Randomized Clinical Trial. JAMA Pediatr. 2022;176:860. doi:10.1001/jamapediatrics.2022.1973
  51. Xu B, Liang S, Zhao J, Li X, Guo J, et al. subsp. XLTG11 improves antibiotic-related diarrhea by alleviating inflammation, enhancing intestinal barrier function and regulating intestinal flora. Food Funct. 2022;13:6404. doi:10.1039/d1fo04305f
  52. Liu B, Wang C, Huasai S, Han A, Zhang J, et al. Compound Probiotics Improve the Diarrhea Rate and Intestinal Microbiota of Newborn Calves. Animals (Basel). 2022;12. doi:10.3390/ani12030322
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