Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 23 Researches
8.2
USERS' SCORE
Moderately Good
Based on 11 Reviews
7.8
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Proprietary Probiotic BlendLacticaseibacillus rhamnosus R0011Lactobacillus helvetius R0052Pediococcus acidilactici R1001Lacticaseibacillus casei R0215Bifidobacterium longum BB536Lactiplantibacillus plantarum R1012Bifidobacterium breve R0070Lactococcus lactis subsp. lactis R1058
131 mg (10 Billion CFU)
†
Top Medical Research Studies
9
Probiotics improve H. pylori treatment
We explored the effect of adding Bifidobacterium longum to standard treatments for Helicobacter pylori, a common cause of gastritis and other gastric issues. By analyzing data from 91 clinical trials with over 13,000 patients, we saw that incorporating this probiotic significantly boosted the rate of H. pylori eradication compared to standard therapy alone.
Moreover, we noted a reduction in unpleasant side effects like nausea and diarrhea for those taking the probiotics, making treatment much more tolerable. Overall, Bifidobacterium longum stands out as an effective partner in H. pylori eradication efforts.
Moreover, we noted a reduction in unpleasant side effects like nausea and diarrhea for those taking the probiotics, making treatment much more tolerable. Overall, Bifidobacterium longum stands out as an effective partner in H. pylori eradication efforts.
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8
We examined how Lactobacillus reuteri DSM 17938 (DSM) influences gastric damage from ethanol in mice. The study showed that DSM notably decreased ulcer area after just three days of treatment.
However, treatment effects reversed when a TRPV1 agonist was introduced, indicating that the protective benefits of DSM rely on inhibiting certain pathways. While DSM helps reduce oxidative stress, it didn't alleviate lesions caused by Substance P.
Through this research, we see potential in DSM for protecting the gastric lining, though its full effectiveness against all factors isn't guaranteed.
However, treatment effects reversed when a TRPV1 agonist was introduced, indicating that the protective benefits of DSM rely on inhibiting certain pathways. While DSM helps reduce oxidative stress, it didn't alleviate lesions caused by Substance P.
Through this research, we see potential in DSM for protecting the gastric lining, though its full effectiveness against all factors isn't guaranteed.
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8
Lactococcus lactis offers gastritis protection
We examined whether an oral vaccine using Lactococcus lactis could provide protection against Helicobacter pylori, a major cause of gastritis. This study utilized two strains of engineered L. lactis that delivered specific antigens.
The results were promising, showing that these strains could induce a strong immune response in mice. Particularly, LL-UreA displayed a remarkable ability to protect against H. pylori infections, with 70% of the mice remaining free of colonization.
Our findings suggest that this approach could serve as an effective method to combat gastritis associated with H. pylori.
The results were promising, showing that these strains could induce a strong immune response in mice. Particularly, LL-UreA displayed a remarkable ability to protect against H. pylori infections, with 70% of the mice remaining free of colonization.
Our findings suggest that this approach could serve as an effective method to combat gastritis associated with H. pylori.
Read More
Most Useful Reviews
7.5
Effective for IBS
8 people found this helpful
I recommend these probiotics. I struggled with flatulence and gastritis for two months. After taking these probiotics three times daily, I felt a slight improvement in a couple of weeks and was quite pleased after a month, as my flatulence nearly disappeared and my gut function improved. I also gave my five-year-old two doses daily after antibiotics, and their bowel movements became regular within days. The capsules are intact after dissolving in warm milk, which indicates live bacteria.
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7.5
Improved gastritis condition
2 people found this helpful
I liked these probiotics and plan to order more. I had ongoing issues with my gut, but after seeing a gastroenterologist, they noted improvements compared to last year. My gastritis persists but is less severe, and the small sores have healed. Overall, I recommend them.
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9
No more cramps
1 people found this helpful
I use these probiotics twice a year and have forgotten about intestinal cramps and gastritis flare-ups. I highly recommend purchasing them.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 23 Researches
8.2
- All Researches
9.5
Probiotics improve H. pylori outcomes
In our exploration of gastritis treatment, we focused on the effectiveness of a 14-day high-dose PPI and bismuth quadruple therapy combined with Lactobacillus probiotics for eradicating Helicobacter pylori.
In a double-blind, placebo-controlled study involving 100 participants, we found that adding probiotics significantly improved the eradication rate to 96% compared to 68% without them. Moreover, the probiotic group experienced fewer side effects, such as nausea and abdominal discomfort.
This suggests that probiotics not only boost treatment success but also enhance patient comfort during therapy.
In a double-blind, placebo-controlled study involving 100 participants, we found that adding probiotics significantly improved the eradication rate to 96% compared to 68% without them. Moreover, the probiotic group experienced fewer side effects, such as nausea and abdominal discomfort.
This suggests that probiotics not only boost treatment success but also enhance patient comfort during therapy.
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9.5
We examined the effectiveness of adding probiotics, including Bifidobacterium lactis, and bismuth to standard triple therapy for treating H. pylori infection in gastritis patients. The study involved randomizing participants into groups receiving either the probiotic combination or a placebo alongside standard medication.
The results were promising, showing a complete eradication rate of H. pylori in 7-day treatment groups, especially where antibiotic resistance was low. Moreover, introducing probiotics helped lessen the side effects of treatment.
The results were promising, showing a complete eradication rate of H. pylori in 7-day treatment groups, especially where antibiotic resistance was low. Moreover, introducing probiotics helped lessen the side effects of treatment.
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9
We explored the impact of Lactobacillus strains, particularly NCFM and Lp-115, on gastritis caused by H. pylori. Through a study involving both human gastric cells and mice, we found that these probiotic strains significantly reduced bacterial adhesion and inflammation in the stomach lining.
The results showed decreased levels of inflammatory markers, indicating that NCFM and Lp-115 could effectively inhibit the inflammation associated with H. pylori infections. Overall, this research suggests promising benefits of these lactobacillus strains for managing gastric health.
The results showed decreased levels of inflammatory markers, indicating that NCFM and Lp-115 could effectively inhibit the inflammation associated with H. pylori infections. Overall, this research suggests promising benefits of these lactobacillus strains for managing gastric health.
Read More
9
We explored the effects of two new lactic acid bacteria strains, MN-LF23 and MN-LG80, on combating infections that can lead to gastritis. Through a detailed analysis, these strains were shown to reduce harmful bacteria significantly—by 90% and 83%, respectively—in affected mice.
Moreover, they appeared to alleviate damage to the gastric lining and lower inflammation markers in the bloodstream. Both strains also positively influenced the gut microbiota, promoting beneficial organisms while reducing harmful ones. Overall, this study suggests promising potential for these bacterial strains in addressing gastritis-related infections.
Moreover, they appeared to alleviate damage to the gastric lining and lower inflammation markers in the bloodstream. Both strains also positively influenced the gut microbiota, promoting beneficial organisms while reducing harmful ones. Overall, this study suggests promising potential for these bacterial strains in addressing gastritis-related infections.
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9
We researched the impact of LF-XY18, a yogurt-derived bacterial strain, on gastric injury caused by hydrochloric acid and ethanol in mice. Over two weeks, we observed that LF-XY18 significantly reduced gastric injury and inflammation compared to a control group.
Mice treated with LF-XY18 showed healthier gastric conditions, with improved antioxidant activity and reduced harmful substances in the body. It seems that a higher dose of LF-XY18 was more beneficial than a lower one, suggesting this strain could potentially help prevent gastric injuries.
Mice treated with LF-XY18 showed healthier gastric conditions, with improved antioxidant activity and reduced harmful substances in the body. It seems that a higher dose of LF-XY18 was more beneficial than a lower one, suggesting this strain could potentially help prevent gastric injuries.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 11 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Effective for IBS
8 people found this helpful
I recommend these probiotics. I struggled with flatulence and gastritis for two months. After taking these probiotics three times daily, I felt a slight improvement in a couple of weeks and was quite pleased after a month, as my flatulence nearly disappeared and my gut function improved. I also gave my five-year-old two doses daily after antibiotics, and their bowel movements became regular within days. The capsules are intact after dissolving in warm milk, which indicates live bacteria.
Read More
7.5
Improved gastritis condition
2 people found this helpful
I liked these probiotics and plan to order more. I had ongoing issues with my gut, but after seeing a gastroenterologist, they noted improvements compared to last year. My gastritis persists but is less severe, and the small sores have healed. Overall, I recommend them.
Read More
9
No more cramps
1 people found this helpful
I use these probiotics twice a year and have forgotten about intestinal cramps and gastritis flare-ups. I highly recommend purchasing them.
Read More
9
Quick action noted
These probiotics began working right away for my gastritis issues and food intolerances. They significantly relieved gas buildup, making me feel much better. I'm committed to continuing their use; I'd suggest trying them!
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7.5
Consistent relief achieved
I've been taking lactic acid bacteria regularly for my gastritis and enteritis. I believe it's effective and suits me well. I recommend it highly.
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Frequently Asked Questions
7.5
Effective for IBS
8 people found this helpful
I recommend these probiotics. I struggled with flatulence and gastritis for two months. After taking these probiotics three times daily, I felt a slight improvement in a couple of weeks and was quite pleased after a month, as my flatulence nearly disappeared and my gut function improved. I also gave my five-year-old two doses daily after antibiotics, and their bowel movements became regular within days. The capsules are intact after dissolving in warm milk, which indicates live bacteria.
9
Quick action noted
These probiotics began working right away for my gastritis issues and food intolerances. They significantly relieved gas buildup, making me feel much better. I'm committed to continuing their use; I'd suggest trying them!
9
Chronic conditions alleviated
After a few months of use, I've noticed improvements with my gastritis and enteritis issues. They seem to help a lot. I recommend these probiotics.
9
No more cramps
1 people found this helpful
I use these probiotics twice a year and have forgotten about intestinal cramps and gastritis flare-ups. I highly recommend purchasing them.
7.5
Helpful supplement
I'm taking these probiotics alongside supplements for my gastritis and believe they are beneficial. I increased my dosage and feel it's making a positive difference.
6
Chronic gastritis relief
1 people found this helpful
I consistently take this product and feel the benefits, especially after suffering from chronic gastritis. I noticed improvements after regular use, but if I stop, symptoms return. I advise taking it post-meal due to my sensitive stomach. The product's packaging is hygienic and delivery was swift.
6
Positive body response
8 people found this helpful
I am using this probiotic complex to combat Helicobacter pylori, which causes gastritis. After a blood test confirmed Helicobacter, I’ve been administering it to my child. I noticed a positive reaction in my sensitive body with no adverse effects. I also supplement with fibre, which helps nourish the probiotics.
2
Ineffective for gastritis
I initially felt unsure about the benefits of ginger, especially with my weak stomach. After consuming it, I found it had little impact on my gastritis and other digestive issues like constipation. While it may work well for those with a healthy stomach, it definitely doesn't suit mine, as it only seemed to worsen my symptoms. I may try it again, but I'm not convinced of its effectiveness for gastritis.
9
We explored the impact of Lactobacillus strains, particularly NCFM and Lp-115, on gastritis caused by H. pylori. Through a study involving both human gastric cells and mice, we found that these probiotic strains significantly reduced bacterial adhesion and inflammation in the stomach lining.
The results showed decreased levels of inflammatory markers, indicating that NCFM and Lp-115 could effectively inhibit the inflammation associated with H. pylori infections. Overall, this research suggests promising benefits of these lactobacillus strains for managing gastric health.
The results showed decreased levels of inflammatory markers, indicating that NCFM and Lp-115 could effectively inhibit the inflammation associated with H. pylori infections. Overall, this research suggests promising benefits of these lactobacillus strains for managing gastric health.
9
Probiotics improve H. pylori treatment
We explored the effect of adding Bifidobacterium longum to standard treatments for Helicobacter pylori, a common cause of gastritis and other gastric issues. By analyzing data from 91 clinical trials with over 13,000 patients, we saw that incorporating this probiotic significantly boosted the rate of H. pylori eradication compared to standard therapy alone.
Moreover, we noted a reduction in unpleasant side effects like nausea and diarrhea for those taking the probiotics, making treatment much more tolerable. Overall, Bifidobacterium longum stands out as an effective partner in H. pylori eradication efforts.
Moreover, we noted a reduction in unpleasant side effects like nausea and diarrhea for those taking the probiotics, making treatment much more tolerable. Overall, Bifidobacterium longum stands out as an effective partner in H. pylori eradication efforts.
8
We explored the effectiveness of the probiotics Lactococcus lactis P135 and Bifidobacterium longum P142 in combating gastritis linked to Helicobacter pylori (HP) in mice. Our findings indicated that these probiotics significantly reduced HP growth and the resulting inflammation. When administered orally, they were able to alleviate symptoms of HP- and aspirin-induced gastritis while also improving cognitive behavior.
Despite the promising results, it’s important to note that the effects were observed in mice, and further research is needed to confirm if these benefits translate to humans.
Despite the promising results, it’s important to note that the effects were observed in mice, and further research is needed to confirm if these benefits translate to humans.
References
- Zhang Z, Huang Y, Wang R, Dong R, Li T, et al. Utilizing chitosan and pullulan for the encapsulation of Lactiplantibacillus plantarum ZJ316 to enhance its vitality in the gastrointestinal tract. Int J Biol Macromol. 2024;260:129624. doi:10.1016/j.ijbiomac.2024.129624
- Shen S, Ren F, Qin H, Bukhari I, Yang J, et al. NCFM and Lp-115 inhibit colonization and gastric inflammation in a murine model. Front Cell Infect Microbiol. 2023;13:1196084. doi:10.3389/fcimb.2023.1196084
- Zhao Y, Li Z, Zhao L, Wang J, Wang F, et al. Two novel lactic acid bacteria, MN-LF23 and MN-LG80, inhibited infection in C57BL/6 mice. Food Funct. 2022;13:11061. doi:10.1039/d2fo02034c
- He C, Peng C, Xu X, Li N, Ouyang Y, et al. Probiotics mitigate Helicobacter pylori-induced gastric inflammation and premalignant lesions in INS-GAS mice with the modulation of gastrointestinal microbiota. Helicobacter. 2022;27:e12898. doi:10.1111/hel.12898
- Saviano A, Brigida M, Migneco A, Gunawardena G, Zanza C, et al. Lactobacillus Reuteri DSM 17938 in Diarrhea and Constipation: Two Sides of the Same Coin?. Medicina (Kaunas). 2021;57. doi:10.3390/medicina57070643
- Huang M, Li S, He Y, Lin C, Sun Y, et al. Modulation of gastrointestinal bacterial in chronic atrophic gastritis model rats by Chinese and west medicine intervention. Microb Cell Fact. 2021;20:31. doi:10.1186/s12934-021-01525-2
- Wang R, Zhou K, Xiong R, Yang Y, Yi R, et al. Pretreatment with XY18 Relieves Gastric Injury Induced by HCl/Ethanol in Mice via Antioxidant and Anti-Inflammatory Mechanisms. Drug Des Devel Ther. 2020;14:5721. doi:10.2147/DDDT.S280429
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- Poonyam P, Chotivitayatarakorn P, Vilaichone RK. High Effective of 14-Day High-Dose PPI- Bismuth-Containing Quadruple Therapy with Probiotics Supplement for Helicobacter Pylori Eradication: A Double Blinded-Randomized Placebo-Controlled Study. Asian Pac J Cancer Prev. 2019;20:2859. doi:10.31557/APJCP.2019.20.9.2859
- Oliveira AP, Souza LKM, Araújo TSL, Araújo S, Nogueira KM, et al. Lactobacillus reuteri DSM 17938 Protects against Gastric Damage Induced by Ethanol Administration in Mice: Role of TRPV1/Substance P Axis. Nutrients. 2019;11. doi:10.3390/nu11010208
- Asgari B, Kermanian F, Derakhshan N, Asna-Ashari M, Sadat ZRN, et al. HONEY-DERIVED LACTOBACILLUS RHAMNOSUS ALLEVIATES HELICOBACTER PYLORI-INDUCED GASTRO-INTESTINAL INFECTION AND GASTRIC INFLAMMATION IN C57BL/6 MICE: AN IMMUNO-HISTOLOGIC STUDY. Arq Gastroenterol. 2018;55:279. doi:10.1590/S0004-2803.201800000-70
- Buckley M, Lacey S, Doolan A, Goodbody E, Seamans K. The effect of supplementation in infection: a placebo-controlled, single-blind study. BMC Nutr. 2018;4:48. doi:10.1186/s40795-018-0257-4
- Shin JW, Shin YJ, Lee DY, Kim DH. Alleviation of Helicobacter pylori- or aspirin-induced gastritis and neuroinflammation in mice by Lactococcus lactis and Bifidobacterium longum. Lett Appl Microbiol. 2024;77. doi:10.1093/lambio/ovae128
- Tanashat M, Abuelazm M, Abouzid M, Al-Ajlouni YA, Ramadan A, et al. Efficacy of probiotics regimens for Helicobacter pylori eradication: A systematic review, pairwise, and network meta-analysis of randomized controlled trials. Clin Nutr ESPEN. 2025;65:424. doi:10.1016/j.clnesp.2024.11.016
- Yakovenko EP, Strokova TV, Iakovenko AV, Ivanov AN, Soluyanova IP, et al. [A prospective randomized comparative study of the efficacy and safety of a two-week bismuth-based quadrotherapy of infection with the inclusion of the probiotic containing Bifidobacterium longum BB-46 and ]. Ter Arkh. 2021;93:916. doi:10.26442/00403660.2021.08.200996
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- Kim JE, Kim MS, Yoon YS, Chung MJ, Yum DY. Use of selected lactic acid bacteria in the eradication of Helicobacter pylori infection. J Microbiol. 2014;52:955. doi:10.1007/s12275-014-4355-y
- Srinarong C, Siramolpiwat S, Wongcha-um A, Mahachai V, Vilaichone RK. Improved eradication rate of standard triple therapy by adding bismuth and probiotic supplement for Helicobacter pylori treatment in Thailand. Asian Pac J Cancer Prev. 2014;15:9909.
- Ni X, Liu Y, Sun M, Jiang Y, Wang Y, et al. Oral Live-Carrier Vaccine of Recombinant Lactococcus lactis Inducing Prophylactic Protective Immunity Against Helicobacter pylori Infection. Probiotics Antimicrob Proteins. 2024. doi:10.1007/s12602-024-10360-x
- Liu W, Tan Z, Liu H, Zeng Z, Luo S, et al. Nongenetically modified Lactococcus lactis-adjuvanted vaccination enhanced innate immunity against Helicobacter pylori. Helicobacter. 2017;22. doi:10.1111/hel.12426
- Liu W, Tan Z, Xue J, Luo W, Song H, et al. Therapeutic efficacy of oral immunization with a non-genetically modified Lactococcus lactis-based vaccine CUE-GEM induces local immunity against Helicobacter pylori infection. Appl Microbiol Biotechnol. 2016;100:6219. doi:10.1007/s00253-016-7333-y
- Zhang L, Wu WK, Gallo RL, Fang EF, Hu W, et al. Critical Role of Antimicrobial Peptide Cathelicidin for Controlling Helicobacter pylori Survival and Infection. J Immunol. 2016;196:1799. doi:10.4049/jimmunol.1500021
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