Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8.1
USERS' SCORE
Moderately Good
Based on 14 Reviews
7.2
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Proprietary Probiotic BlendLacticaseibacillus rhamnosus R0011Lactobacillus helvetius R0052Pediococcus acidilactici R1001Lacticaseibacillus casei R0215Bifidobacterium longum BB536Lactiplantibacillus plantarum R1012Bifidobacterium breve R0070Lactococcus lactis subsp. lactis R1058
131 mg (10 Billion CFU)

Top Medical Research Studies

9
Lb41 may protect liver health
We explored the effects of Lactiplantibacillus plantarum Lb41 on nonalcoholic fatty liver disease (NAFLD) in mice fed a high-fat diet. After treatment with Lb41, we observed significant reductions in body weight and harmful serum lipids, indicating its potential benefits.

Additionally, Lb41 appeared to alleviate liver damage and improve metabolic markers, suggesting a protective effect against fatty liver disease. While results are promising, further research is necessary to fully understand the implications for human health.
Read More
9
MP108 benefits jaundice treatment
We examined how Lactobacillus rhamnosus MP108 affects hemolytic jaundice in rats. After one week of dietary MP108, we noted important improvements in body weight and liver function, indicated by normalized levels of various enzymes and bilirubin. Tissues from the liver and intestines showed healing effects, and our analysis revealed changes in gut bacteria that correlated with these health improvements. Overall, this study highlights the potential of MP108 to alleviate jaundice symptoms by supporting liver health through microbiome alterations.
Read More
8
Lactobacillus vesicles aid liver health
We examined the effects of lactobacillus-derived extracellular vesicles (LAB-EVs) on liver health, especially in relation to alcohol-induced damage. Through a systematic study involving three different LAB-EVs, we observed significant reductions in liver injury, including improvements in liver function and inflammation.

Notably, these LAB-EVs also enhanced intestinal flora diversity and activated key liver proteins like Nrf-2. This suggests that LAB-EVs play a protective role, potentially making fermented foods an accessible way to support liver health.
Read More

Most Useful Reviews

0
Immediate relief
24 people found this helpful
I had high hopes for this drug due to the positive reviews I read. However, I began experiencing constant bloating and stabbing pain in my liver after a week. Initially, I thought it was a coincidence, but the discomfort persisted daily. I decided to stop taking the probiotics, and I immediately felt relief; the swelling and pain disappeared the very next day. It seems I have some idiosyncrasy, as prior to these probiotics, I had no such issues.
Read More
9
Normalised bowel function
8 people found this helpful
Six months post-appendectomy, I faced issues with bowel movements, but these probiotics have changed my life. After starting them, I found relief by the second week, and now my toilet visits are comfortable rather than distressing. My bowel function has normalised, and I’ve had no relapses since. I highly recommend them to others experiencing similar issues; they truly work wonders for me.
Read More
9
Effective treatment
1 people found this helpful
At last, a friend recommended Jarro to me. Initially, I was hesitant due to previous failures with similar products. However, after three to four weeks, the results were remarkable. I had endured stomach issues for years, but now I finally have a product that provides relief. I do not go without it anymore. Thank you to my friend and a massive thanks to Jarro.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8.1
  • All Researches
9
Lb41 may protect liver health
We explored the effects of Lactiplantibacillus plantarum Lb41 on nonalcoholic fatty liver disease (NAFLD) in mice fed a high-fat diet. After treatment with Lb41, we observed significant reductions in body weight and harmful serum lipids, indicating its potential benefits.

Additionally, Lb41 appeared to alleviate liver damage and improve metabolic markers, suggesting a protective effect against fatty liver disease. While results are promising, further research is necessary to fully understand the implications for human health.
Read More
9
MP108 benefits jaundice treatment
We examined how Lactobacillus rhamnosus MP108 affects hemolytic jaundice in rats. After one week of dietary MP108, we noted important improvements in body weight and liver function, indicated by normalized levels of various enzymes and bilirubin. Tissues from the liver and intestines showed healing effects, and our analysis revealed changes in gut bacteria that correlated with these health improvements. Overall, this study highlights the potential of MP108 to alleviate jaundice symptoms by supporting liver health through microbiome alterations.
Read More
8
Lactobacillus effects on liver health
We assessed the impact of LF-166, a probiotic from yak yogurt, on liver health in mice fed a high-fat diet. Our findings showed that LF-166 not only reduced body weight and blood lipid levels but also alleviated liver steatosis and improved gut health. Furthermore, we noticed changes in gut microbiota composition, revealing an enhanced diversity. However, while LF-166 shows promise in managing hyperlipidemia, further studies are needed to firmly establish its effectiveness and applicability in humans.
Read More
8
JCF enhances liver disease treatment
We investigated how JiGuCao Capsule formula (JCF) can help treat metabolic-associated fatty liver disease (MAFLD). Using a mouse model, we observed that JCF positively influences liver health by enhancing intestinal function and adjusting gut bacteria. The mice that received JCF showed reduced liver fat and improved metabolism compared to those without treatment. While our findings are promising, more clinical studies on humans are essential to confirm JCF's effectiveness in managing MAFLD.
Read More
8
Probiotics provide potential NASH treatment
We investigated the potential of a probiotic and aged garlic extract combination to treat nonalcoholic steatohepatitis (NASH), a serious liver condition. Using a rat model, our study employed both laboratory and animal tests to look at inflammation levels and various biochemical markers in liver tissues.

The results showed that this synbiotic therapy reduced liver inflammation by impacting key proteins related to fatty liver disease. However, while there was a reduction in some inflammatory signals, the overall benefits for treating NASH are still unclear.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 14 Reviews
7.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
0
Immediate relief
24 people found this helpful
I had high hopes for this drug due to the positive reviews I read. However, I began experiencing constant bloating and stabbing pain in my liver after a week. Initially, I thought it was a coincidence, but the discomfort persisted daily. I decided to stop taking the probiotics, and I immediately felt relief; the swelling and pain disappeared the very next day. It seems I have some idiosyncrasy, as prior to these probiotics, I had no such issues.
Read More
9
Normalised bowel function
8 people found this helpful
Six months post-appendectomy, I faced issues with bowel movements, but these probiotics have changed my life. After starting them, I found relief by the second week, and now my toilet visits are comfortable rather than distressing. My bowel function has normalised, and I’ve had no relapses since. I highly recommend them to others experiencing similar issues; they truly work wonders for me.
Read More
9
Effective treatment
1 people found this helpful
At last, a friend recommended Jarro to me. Initially, I was hesitant due to previous failures with similar products. However, after three to four weeks, the results were remarkable. I had endured stomach issues for years, but now I finally have a product that provides relief. I do not go without it anymore. Thank you to my friend and a massive thanks to Jarro.
Read More
9
Noteworthy relief
I felt completely bewildered but had a surprising experience. Yesterday, I faced severe constipation during my pregnancy and ate something, leading to an unexpected result. This morning, I was finally able to use the bathroom! It’s incredible how this product assists with my constipation, allowing me a sense of comfort I had been missing.
Read More
7.5
Preventive measures
10 people found this helpful
I've dealt with diverticulitis for years and have suffered significant pain. To help prevent flare-ups, I take this probiotic as part of my health regimen. It's become vital in managing my intestinal environment and constipation, supporting my overall gut health. While not all individuals might experience the same results, it has helped me to maintain control over my condition effectively.
Read More

Frequently Asked Questions

9
Effective treatment
1 people found this helpful
At last, a friend recommended Jarro to me. Initially, I was hesitant due to previous failures with similar products. However, after three to four weeks, the results were remarkable. I had endured stomach issues for years, but now I finally have a product that provides relief. I do not go without it anymore. Thank you to my friend and a massive thanks to Jarro.
9
Normalised bowel function
8 people found this helpful
Six months post-appendectomy, I faced issues with bowel movements, but these probiotics have changed my life. After starting them, I found relief by the second week, and now my toilet visits are comfortable rather than distressing. My bowel function has normalised, and I’ve had no relapses since. I highly recommend them to others experiencing similar issues; they truly work wonders for me.
6
Gentle effect
I believe this product is somewhat effective. I purchased it because I do not usually consume well-known products, and after nearly a month, I do feel a slight easing of my symptoms, which is a positive change.
7.5
Effective probiotic benefits
43 people found this helpful
This probiotic has proven to be remarkably effective right from the first use. I was hesitant due to the cost, but it has improved my digestive health significantly. The strength and type of beneficial bacteria it contains have led to better immunity, enhanced skin condition, and an uplift in my mood overall. I'm truly delighted to have discovered and incorporated this into my routine.
7.5
Preventive measures
10 people found this helpful
I've dealt with diverticulitis for years and have suffered significant pain. To help prevent flare-ups, I take this probiotic as part of my health regimen. It's become vital in managing my intestinal environment and constipation, supporting my overall gut health. While not all individuals might experience the same results, it has helped me to maintain control over my condition effectively.
9
Quick effects
1 people found this helpful
The product acts immediately! I can feel a notable easing effect shortly after taking it, which has been very beneficial.
0
Immediate relief
24 people found this helpful
I had high hopes for this drug due to the positive reviews I read. However, I began experiencing constant bloating and stabbing pain in my liver after a week. Initially, I thought it was a coincidence, but the discomfort persisted daily. I decided to stop taking the probiotics, and I immediately felt relief; the swelling and pain disappeared the very next day. It seems I have some idiosyncrasy, as prior to these probiotics, I had no such issues.
6
Improve Crohn's disease
2 people found this helpful
I find this probiotic helpful for managing my Crohn's disease. It complements my overall treatment well. I've noticed significant improvements in my condition, encouraging me to continue using it consistently.
9
Lb41 may protect liver health
We explored the effects of Lactiplantibacillus plantarum Lb41 on nonalcoholic fatty liver disease (NAFLD) in mice fed a high-fat diet. After treatment with Lb41, we observed significant reductions in body weight and harmful serum lipids, indicating its potential benefits.

Additionally, Lb41 appeared to alleviate liver damage and improve metabolic markers, suggesting a protective effect against fatty liver disease. While results are promising, further research is necessary to fully understand the implications for human health.
8
Lactobacillus effects on liver health
We assessed the impact of LF-166, a probiotic from yak yogurt, on liver health in mice fed a high-fat diet. Our findings showed that LF-166 not only reduced body weight and blood lipid levels but also alleviated liver steatosis and improved gut health. Furthermore, we noticed changes in gut microbiota composition, revealing an enhanced diversity. However, while LF-166 shows promise in managing hyperlipidemia, further studies are needed to firmly establish its effectiveness and applicability in humans.
8
JCF enhances liver disease treatment
We investigated how JiGuCao Capsule formula (JCF) can help treat metabolic-associated fatty liver disease (MAFLD). Using a mouse model, we observed that JCF positively influences liver health by enhancing intestinal function and adjusting gut bacteria. The mice that received JCF showed reduced liver fat and improved metabolism compared to those without treatment. While our findings are promising, more clinical studies on humans are essential to confirm JCF's effectiveness in managing MAFLD.

References

  1. Lee NK, Lee Y, Shin DS, Park E, Paik HD. Probiotic Lactiplantibacillus plantarum Lb41 alleviates high-fat diet-induced nonalcoholic fatty liver disease in mice. Nutrition. 2025;134:112735. doi:10.1016/j.nut.2025.112735
  2. Zhang S, Xu L, Zhu C, Li J, Fu Y, et al. 166, Derived from Yak Yogurt from Tibetan Areas of Sichuan, Improves High-Fat-Diet-Induced Hyperlipidemia by Modulating Gut Microbiota and Liver- and Gut-Related Pathways. Foods. 2025;14. doi:10.3390/foods14050867
  3. Qi W, Cao X, Chen Y, Chen H, Zhang N, et al. JiGuCao capsule formula alleviates metabolic fatty liver disease by regulating the gut-liver axis and lipid metabolism. Phytomedicine. 2025;140:156559. doi:10.1016/j.phymed.2025.156559
  4. Sharma D, Patel D, Mandal P. In Vitro, In Vivo, and In Silico Investigation of Synbiotic-Mediated Activation of PPAR- Curtails Nonalcoholic Steatohepatitis (NASH) in Wistar Rats by Inhibiting PNPLA3/SREBP1-c Lead Inflammatory Injury of Hepatic Cells. Mediators Inflamm. 2025;2025:9948679. doi:10.1155/mi/9948679
  5. Liu C, Wang Y, Sheng L, Zhang Y, Luo G, et al. 3-Hydroxypropionaldehyde modulates tryptophan metabolism to activate AhR signaling and alleviate ethanol-induced liver injury. Phytomedicine. 2025;139:156445. doi:10.1016/j.phymed.2025.156445
  6. Wu G, Ai Q, Shi Y. Oral administration of Lactobacillus rhamnosus MP108 ameliorates hemolytic jaundice in rats. J Food Sci. 2025;90:e17671. doi:10.1111/1750-3841.17671
  7. Lv Y, Chu J, Zhang X, Li X, Yin A. Synbiotics effects of d-tagatose and Lactobacillus rhamnosus GG on the inflammation and oxidative stress reaction of Gallus gallus based on the genus of cecal bacteria and their metabolites. PLoS One. 2025;20:e0317825. doi:10.1371/journal.pone.0317825
  8. Jiao Q, Liu J, Zhou L, McClements DJ, Liu W, et al. extracellular vesicles alleviate alcohol-induced liver injury in mice by regulating gut microbiota and activating the Nrf-2 signaling pathway. Food Funct. 2025;16:1284. doi:10.1039/d4fo04364b
  9. Zhu Y, Pan Y, Wang X, Wei L, Zhu L, et al. GG Combined with Metformin Alleviates Alcohol-Induced Liver Inflammation in Mice by Maintaining the Intestinal Barrier and Regulating Treg/Th1 Cells. J Med Food. 2025. doi:10.1089/jmf.2024.k.0184
  10. Jang H, Joung H, Chu J, Cho M, Kim YW, et al. subsp. CKDB001 Ameliorates Metabolic Complications in High-Fat Diet-Induced Obese Mice. Nutrients. 2024;16. doi:10.3390/nu16244260
  11. Kurakawa T, Kani K, Chudan S, Nishikawa M, Tabuchi Y, et al. Rice Kefiran Ameliorates Obesity and Hepatic Steatosis Through the Change in Gut Microbiota. Microorganisms. 2024;12. doi:10.3390/microorganisms12122495
  12. Hewady S, Manuel CR, Pasquali C, Koya J, Reznik SE. OM-85 attenuates high-fat diet-induced obesity, insulin resistance, gut dysbiosis and nonalcoholic steatohepatitis in a murine model. Biomed Pharmacother. 2024;181:117710. doi:10.1016/j.biopha.2024.117710
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