5/20/2025
Last update
5/20/2025
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.5
USERS' SCORE
Good
Based on 20 Reviews
8.3
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Proprietary Probiotic BlendLacticaseibacillus rhamnosus R0011Lactobacillus helvetius R0052Pediococcus acidilactici R1001Lacticaseibacillus casei R0215Bifidobacterium longum BB536Lactiplantibacillus plantarum R1012Bifidobacterium breve R0070Lactococcus lactis subsp. lactis R1058
131 mg (10 Billion CFU)
†
Top Medical Research Studies
9
Lactobacillus improves infant reflux symptoms
We explored the impact of Lactobacillus reuteri NCIMB 30351 on common gastrointestinal issues in infants, focusing on gastroesophageal reflux. Conducted as a randomized and placebo-controlled trial, 90 infants received either the probiotic drops or a placebo for 25 days.
Our findings revealed that the probiotic significantly reduced regurgitation and crying times while increasing bowel movements in infants with constipation. However, it didn't show strong effects on diarrhea. Overall, Lactobacillus reuteri appears to be a safe and effective option for managing reflux and colic in newborns.
Our findings revealed that the probiotic significantly reduced regurgitation and crying times while increasing bowel movements in infants with constipation. However, it didn't show strong effects on diarrhea. Overall, Lactobacillus reuteri appears to be a safe and effective option for managing reflux and colic in newborns.
Read More
8
Lactobacillus reduces heartburn symptoms
We investigated the impact of heat-killed Lactobacillus No. 1088 on gastroesophageal reflux symptoms in healthy volunteers. In a carefully designed study, 120 participants were randomly assigned to either the Lactobacillus group or placebo for six weeks.
We observed that those taking Lactobacillus experienced significant improvement in heartburn symptoms compared to the placebo group. Overall, it seems that this lactobacillus strain could offer some relief for occasional heartburn in healthy individuals without severe side effects.
We observed that those taking Lactobacillus experienced significant improvement in heartburn symptoms compared to the placebo group. Overall, it seems that this lactobacillus strain could offer some relief for occasional heartburn in healthy individuals without severe side effects.
Read More
8
Lactobacillus reduces gastrointestinal disorders
We investigated whether giving Lactobacillus reuteri DSM 17938 to newborns in their first three months could help prevent infantile colic, reflux, and constipation. In a well-designed study across nine hospitals in Italy, 589 infants received either the probiotic or a placebo.
Parents documented various health and feeding issues in a diary. The results showed that this probiotic did cut down on daily crying times, regurgitation, and constipation, benefiting both families and healthcare costs.
Parents documented various health and feeding issues in a diary. The results showed that this probiotic did cut down on daily crying times, regurgitation, and constipation, benefiting both families and healthcare costs.
Read More
Most Useful Reviews
10
No side effects
99 people found this helpful
Jarrow Probiotics are a wonderful remedy for acid reflux and heartburn. I previously took various medications that worsened my stomach issues, but these probiotics were recommended to me, and they have worked flawlessly. I no longer experience any reflux or heartburn and can eat whatever I like without side effects. However, it is essential to take it for a few weeks to notice the benefits, and daily use is necessary for ongoing results. This product is a natural maintenance solution for digestive health.
Read More
7.5
IBS improvement
25 people found this helpful
I'm surprised! I have tried probiotics before and they did nothing. This product is different; my IBS and reflux have noticeably improved in just four weeks. It's not perfect yet, but I'm hopeful for further improvement.
Read More
9
Coughing relief
14 people found this helpful
Wonderful for acid reflux and IBS. I had severe issues with IBS and acid reflux while on generic Pepcid, which did not alleviate the coughing and choking after eating. This product has stopped all of that. I was on medication for a year and a half that caused bone degeneration, so I needed an alternative. Now, I take one pill on an empty stomach in the morning and another before lunch and bedtime. Thank goodness for this product, which has genuinely improved my situation!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 19 Researches
7.5
- All Researches
9
Lactobacillus improves infant reflux symptoms
We explored the impact of Lactobacillus reuteri NCIMB 30351 on common gastrointestinal issues in infants, focusing on gastroesophageal reflux. Conducted as a randomized and placebo-controlled trial, 90 infants received either the probiotic drops or a placebo for 25 days.
Our findings revealed that the probiotic significantly reduced regurgitation and crying times while increasing bowel movements in infants with constipation. However, it didn't show strong effects on diarrhea. Overall, Lactobacillus reuteri appears to be a safe and effective option for managing reflux and colic in newborns.
Our findings revealed that the probiotic significantly reduced regurgitation and crying times while increasing bowel movements in infants with constipation. However, it didn't show strong effects on diarrhea. Overall, Lactobacillus reuteri appears to be a safe and effective option for managing reflux and colic in newborns.
Read More
9
This double-blind, randomized controlled trial explored the use of a specialized infant formula with Lactobacillus reuteri DSM 17938 to reduce functional regurgitation (FR) in infants. We found that infants consuming the test formula experienced a significant decrease in regurgitation frequency—from an average of 7.4 to 2.6 regurgitations per day—compared to smaller changes in the control group. Additionally, gastric emptying improved more in the test group, suggesting this combination could offer benefits for managing FR in infants.
Read More
9
We aimed to explore the effectiveness of a specific probiotic mixture called Ecologic®Relief in treating constipation among pregnant women. Over four weeks, participants reported significant improvements in their bowel habits, including increased defecation frequency and reduced sensations of obstruction and incomplete evacuation.
Importantly, we noted that the probiotic mixture also seemed to decrease reflux episodes from 60% to 20%. This suggests that not only does Ecologic®Relief help with constipation, but it may also provide relief from reflux symptoms during pregnancy. We believe more extensive studies will be beneficial to confirm these findings.
Importantly, we noted that the probiotic mixture also seemed to decrease reflux episodes from 60% to 20%. This suggests that not only does Ecologic®Relief help with constipation, but it may also provide relief from reflux symptoms during pregnancy. We believe more extensive studies will be beneficial to confirm these findings.
Read More
8
Probiotic supplement reduces GERD symptoms
We explored the effects of a dietary supplement containing probiotics, bioactive peptides, and vitamins on heartburn and quality of life in individuals with mild-to-moderate gastroesophageal reflux disease (GERD). In a well-structured, randomized, double-blind, placebo-controlled study involving 56 adults over 28 days, we noted a significant reduction in heartburn frequency and severity in those taking the supplement compared to the placebo group.
Participants also reported taking fewer over-the-counter medications and recognized improvements in their overall quality of life.
Participants also reported taking fewer over-the-counter medications and recognized improvements in their overall quality of life.
Read More
8
Lactobacillus reduces heartburn symptoms
We investigated the impact of heat-killed Lactobacillus No. 1088 on gastroesophageal reflux symptoms in healthy volunteers. In a carefully designed study, 120 participants were randomly assigned to either the Lactobacillus group or placebo for six weeks.
We observed that those taking Lactobacillus experienced significant improvement in heartburn symptoms compared to the placebo group. Overall, it seems that this lactobacillus strain could offer some relief for occasional heartburn in healthy individuals without severe side effects.
We observed that those taking Lactobacillus experienced significant improvement in heartburn symptoms compared to the placebo group. Overall, it seems that this lactobacillus strain could offer some relief for occasional heartburn in healthy individuals without severe side effects.
Read More
User Reviews
USERS' SCORE
Good
Based on 20 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
10
No side effects
99 people found this helpful
Jarrow Probiotics are a wonderful remedy for acid reflux and heartburn. I previously took various medications that worsened my stomach issues, but these probiotics were recommended to me, and they have worked flawlessly. I no longer experience any reflux or heartburn and can eat whatever I like without side effects. However, it is essential to take it for a few weeks to notice the benefits, and daily use is necessary for ongoing results. This product is a natural maintenance solution for digestive health.
Read More
7.5
IBS improvement
25 people found this helpful
I'm surprised! I have tried probiotics before and they did nothing. This product is different; my IBS and reflux have noticeably improved in just four weeks. It's not perfect yet, but I'm hopeful for further improvement.
Read More
9
Coughing relief
14 people found this helpful
Wonderful for acid reflux and IBS. I had severe issues with IBS and acid reflux while on generic Pepcid, which did not alleviate the coughing and choking after eating. This product has stopped all of that. I was on medication for a year and a half that caused bone degeneration, so I needed an alternative. Now, I take one pill on an empty stomach in the morning and another before lunch and bedtime. Thank goodness for this product, which has genuinely improved my situation!
Read More
8
Improves digestion
6 people found this helpful
Helpful Aid in Acid Reflux. I suffer from severe acid reflux and can’t eat tomato sauce or most citrus fruits. Since discovering the Jarrow-dophilus probiotic, my situation has greatly improved. While I still suffer from reflux, taking this probiotic 3-4 times a day keeps my symptoms manageable and allows me to enjoy certain foods occasionally without suffering. Within a week, I noticed significant improvements in my digestion. I highly recommend this brand for anyone looking to enhance their overall digestive health.
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7.5
Immediate relief
5 people found this helpful
After undergoing numerous tests with no relief, I tried this product on my cousin's recommendation. Within a week, I experienced relief from my reflux and have reordered since.
Read More
Frequently Asked Questions
7.5
Immediate relief
5 people found this helpful
After undergoing numerous tests with no relief, I tried this product on my cousin's recommendation. Within a week, I experienced relief from my reflux and have reordered since.
7.5
IBS improvement
25 people found this helpful
I'm surprised! I have tried probiotics before and they did nothing. This product is different; my IBS and reflux have noticeably improved in just four weeks. It's not perfect yet, but I'm hopeful for further improvement.
0
Effective alternative found
3 people found this helpful
This brand did not work for me. However, when I tried Dr. Ohhira's, I felt a difference immediately. It's more expensive, but it resolved my IBS and eliminated my reflux and gas completely over three months.
9
No more antacids
2 people found this helpful
I had serious reflux and relied on antacids for five years. Since starting these probiotics, I've stopped using them altogether and feel much better. I'm grateful to have found this product!
7.5
Reduced prescriptions
3 people found this helpful
My husband suffered from severe reflux, but since taking these (one in the morning and one in the evening), he rarely needs his prescription medication. He only occasionally requires a natural antacid tablet now.
9
Major symptom reduction
This product is magic! After suffering from silent reflux and IBS for four years, I finally feel well. Almost all my symptoms have dissipated with its help.
1
Worsened my reflux
I have severe reflux, and this product made it worse, forcing me to stop taking it. I don't recommend it for anyone with reflux.
9
Reduced reflux severity
Great digestive aid. I received this as a free sample, and during the week I took this supplement, I only needed to use an acid reducer once. I have severe acid reflux, which was so bad it burned into my ears. I almost had to stop consuming solid food. I returned and purchased a full package.
7.5
Bloating relief
2 people found this helpful
Fantastic product! I've transitioned from inferior probiotics to this one, which helps with bloating, indigestion, and reflux. I only take one every other day and it works perfectly.
8
Probiotic supplement reduces GERD symptoms
We explored the effects of a dietary supplement containing probiotics, bioactive peptides, and vitamins on heartburn and quality of life in individuals with mild-to-moderate gastroesophageal reflux disease (GERD). In a well-structured, randomized, double-blind, placebo-controlled study involving 56 adults over 28 days, we noted a significant reduction in heartburn frequency and severity in those taking the supplement compared to the placebo group.
Participants also reported taking fewer over-the-counter medications and recognized improvements in their overall quality of life.
Participants also reported taking fewer over-the-counter medications and recognized improvements in their overall quality of life.
8
Lactobacillus reduces heartburn symptoms
We investigated the impact of heat-killed Lactobacillus No. 1088 on gastroesophageal reflux symptoms in healthy volunteers. In a carefully designed study, 120 participants were randomly assigned to either the Lactobacillus group or placebo for six weeks.
We observed that those taking Lactobacillus experienced significant improvement in heartburn symptoms compared to the placebo group. Overall, it seems that this lactobacillus strain could offer some relief for occasional heartburn in healthy individuals without severe side effects.
We observed that those taking Lactobacillus experienced significant improvement in heartburn symptoms compared to the placebo group. Overall, it seems that this lactobacillus strain could offer some relief for occasional heartburn in healthy individuals without severe side effects.
9
This double-blind, randomized controlled trial explored the use of a specialized infant formula with Lactobacillus reuteri DSM 17938 to reduce functional regurgitation (FR) in infants. We found that infants consuming the test formula experienced a significant decrease in regurgitation frequency—from an average of 7.4 to 2.6 regurgitations per day—compared to smaller changes in the control group. Additionally, gastric emptying improved more in the test group, suggesting this combination could offer benefits for managing FR in infants.
8
We examined the effects of Bifidobacterium lactis as a complementary treatment for reflux esophagitis (RE) in a randomized, double-blind, placebo-controlled study. A total of 110 RE patients received rabeprazole while being supplemented with either Bifidobacterium or a placebo over 8 weeks.
Our findings showed that the probiotic group experienced quicker symptom relief and a longer time before symptoms returned, compared to the placebo. We also noted improvements in gut microbiota diversity following the treatment. Thus, Bifidobacterium lactis appears to provide significant benefits as an adjunct therapy for managing reflux symptoms.
Our findings showed that the probiotic group experienced quicker symptom relief and a longer time before symptoms returned, compared to the placebo. We also noted improvements in gut microbiota diversity following the treatment. Thus, Bifidobacterium lactis appears to provide significant benefits as an adjunct therapy for managing reflux symptoms.
References
- Tursi F, Benedetto E, Spina A, De Ponti I, Amone F, et al. Efficacy of a Food Supplement Containing LA14, Peptides, and a Multivitamin Complex in Improving Gastroesophageal Reflux Disease-Related Outcomes and Quality of Life of Subjects Showing Mild-to-Moderate Gastroesophageal Reflux Disease. Nutrients. 2024;16. 10.3390/nu16111759
- Komatsu Y, Miura H, Iwama Y, Urita Y. Beneficial Effect of Heat-Killed Lactic Acid Bacterium No. 1088 on Temporal Gastroesophageal Reflux-Related Symptoms in Healthy Volunteers: A Randomized, Placebo-Controlled, Double-Blind, Parallel-Group Study. Nutrients. 2024;16. 10.3390/nu16081230
- Ethier R, Krishnamurthy A, Jeffrey M, Tompkins TA. Profiling of Metabolites in a Fermented Soy Dietary Supplement Reinforces its Role in the Management of Intestinal Inflammation. Mol Nutr Food Res. 2024;68:e2300770. 10.1002/mnfr.202300770
- Tyrsin OY, Tyrsin DY, Nemenov DG, Ruzov AS, Odintsova VE, et al. Effect of Lactobacillus reuteri NCIMB 30351 drops on symptoms of infantile functional gastrointestinal disorders and gut microbiota in early infants: Results from a randomized, placebo-controlled clinical trial. Eur J Pediatr. 2024;183:2311. 10.1007/s00431-024-05473-y
- Bernard JN, Chinnaiyan V, Almeda J, Catala-Valentin A, Andl CD. sp. Facilitate the Repair of DNA Damage Caused by Bile-Induced Reactive Oxygen Species in Experimental Models of Gastroesophageal Reflux Disease. Antioxidants (Basel). 2023;12. 10.3390/antiox12071314
- Fatani A, Vaher K, Rivero-Mendoza D, Alabasi K, Dahl WJ. Fermented soy supplementation improves indicators of quality of life: a randomized, placebo-controlled, double-blind trial in adults experiencing heartburn. BMC Res Notes. 2020;13:364. 10.1186/s13104-020-05205-z
- Horvath A, Leber B, Feldbacher N, Steinwender M, Komarova I, et al. The effects of a multispecies synbiotic on microbiome-related side effects of long-term proton pump inhibitor use: A pilot study. Sci Rep. 2020;10:2723. 10.1038/s41598-020-59550-x
- Belei O, Olariu L, Dobrescu A, Marcovici T, Marginean O. Is It Useful to Administer Probiotics Together With Proton Pump Inhibitors in Children With Gastroesophageal Reflux?. J Neurogastroenterol Motil. 2018;24:51. 10.5056/jnm17059
- Indrio F, Riezzo G, Giordano P, Ficarella M, Miolla MP, et al. Effect of a Partially Hydrolysed Whey Infant Formula Supplemented with Starch and Lactobacillus reuteri DSM 17938 on Regurgitation and Gastric Motility. Nutrients. 2017;9. 10.3390/nu9111181
- Suzuki T, Masui A, Nakamura J, Shiozawa H, Aoki J, et al. Yogurt Containing Lactobacillus gasseri Mitigates Aspirin-Induced Small Bowel Injuries: A Prospective, Randomized, Double-Blind, Placebo-Controlled Trial. Digestion. 2017;95:49. 10.1159/000452361
- Fujiwara Y, Watanabe T, Muraki M, Yamagami H, Tanigawa T, et al. Association between chronic use of proton pump inhibitors and small- intestinal bacterial overgrowth assessed using lactulose hydrogen breath tests. Hepatogastroenterology. 2015;62:268.
- Aiba Y, Nakano Y, Koga Y, Takahashi K, Komatsu Y. A highly acid-resistant novel strain of Lactobacillus johnsonii No. 1088 has antibacterial activity, including that against Helicobacter pylori, and inhibits gastrin-mediated acid production in mice. Microbiologyopen. 2015;4:465. 10.1002/mbo3.252
- Compare D, Rocco A, Sgamato C, Coccoli P, Campo SM, et al. Lactobacillus paracasei F19 versus placebo for the prevention of proton pump inhibitor-induced bowel symptoms: a randomized clinical trial. Dig Liver Dis. 2015;47:273. 10.1016/j.dld.2015.01.004
- Igarashi M, Nagano J, Tsuda A, Suzuki T, Koike J, et al. Correlation between the Serum Pepsinogen I Level and the Symptom Degree in Proton Pump Inhibitor-Users Administered with a Probiotic. Pharmaceuticals (Basel). 2014;7:754. 10.3390/ph7070754
- Garofoli F, Civardi E, Indrio F, Mazzucchelli I, Angelini M, et al. The early administration of Lactobacillus reuteri DSM 17938 controls regurgitation episodes in full-term breastfed infants. Int J Food Sci Nutr. 2014;65:646. 10.3109/09637486.2014.898251
- Indrio F, Di Mauro A, Riezzo G, Civardi E, Intini C, et al. Prophylactic use of a probiotic in the prevention of colic, regurgitation, and functional constipation: a randomized clinical trial. JAMA Pediatr. 2014;168:228. 10.1001/jamapediatrics.2013.4367
- Gan L, Wang Y, Huang S, Zheng L, Feng Q, et al. Therapeutic Evaluation of subsp. MH-02 as an Adjunctive Treatment in Patients with Reflux Esophagitis: A Randomized, Double-Blind, Placebo-Controlled Trial. Nutrients. 2024;16. 10.3390/nu16030342
- de Milliano I, Tabbers MM, van der Post JA, Benninga MA. Is a multispecies probiotic mixture effective in constipation during pregnancy? 'A pilot study'. Nutr J. 2012;11:80. 10.1186/1475-2891-11-80
- Waller PA, Gopal PK, Leyer GJ, Ouwehand AC, Reifer C, et al. Dose-response effect of Bifidobacterium lactis HN019 on whole gut transit time and functional gastrointestinal symptoms in adults. Scand J Gastroenterol. 2011;46:1057. 10.3109/00365521.2011.584895
