Reviewed By
Overview
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
5
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.9
Supplement Facts
Serving Size: 2 Veg Capsules
Amount Per Serving
%DV
Acetyl-L-Carnitine (from Acetyl-L-Carnitine HCl)
1 g (1,000 mg)
**
Top Medical Research Studies
2
We conducted a robust study comparing acetyl-l-carnitine to a placebo for preventing migraines.
In a triple-blind, crossover design, 72 participants aged 18-65 received either the treatment or placebo for 12 weeks.
Unfortunately, our findings showed no significant differences in headache days between the two groups, meaning acetyl-l-carnitine did not prove effective as a preventive measure for migraines.
In a triple-blind, crossover design, 72 participants aged 18-65 received either the treatment or placebo for 12 weeks.
Unfortunately, our findings showed no significant differences in headache days between the two groups, meaning acetyl-l-carnitine did not prove effective as a preventive measure for migraines.
Read More
8
We looked into how various metabolic factors relate to migraines in patients with patent foramen ovale (PFO). Our study involved 11 PFO patients undergoing surgery and 11 healthy controls.
We found notable differences in certain metabolites like acetylcarnitine and dopamine between the groups. After the surgery, PFO patients experienced significant reductions in headache frequency and severity.
However, while their headaches improved, other migraine symptoms didn't change significantly. Overall, the surgery showed promise in alleviating migraines associated with PFO.
We found notable differences in certain metabolites like acetylcarnitine and dopamine between the groups. After the surgery, PFO patients experienced significant reductions in headache frequency and severity.
However, while their headaches improved, other migraine symptoms didn't change significantly. Overall, the surgery showed promise in alleviating migraines associated with PFO.
Read More
Most Useful Reviews
10
Migraine relief
Excellent product; I'm very pleased with my purchase. These capsules are easy to swallow without tasting them. Previously, I used a brand with large, chalky, and odorous pills. While these capsules do have a slight smell, you can take them before noticing it, and they are far less pungent than the last brand. NAC has numerous health benefits (look up NAC and glycine!), but the most significant for me is its apparent elimination of my near migraine-level headaches. Good packaging.
Read More
7.5
Notable improvements
3 people found this helpful
We frequently host the entire family. Acetyl-L-Carnitine is the best form for absorption. A teenager with disabilities and migraines takes this supplement along with a basic protocol, and the improvements are noticeable over the year.
Read More
6
Helps migraines
2 people found this helpful
It was recommended to strengthen the brain's blood vessels. My acupuncturist suggested this to help counteract the debilitating effects of frequent migraines. It appears to work, but it's difficult to ascertain.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 2 Researches
5
- All Researches
8
We looked into how various metabolic factors relate to migraines in patients with patent foramen ovale (PFO). Our study involved 11 PFO patients undergoing surgery and 11 healthy controls.
We found notable differences in certain metabolites like acetylcarnitine and dopamine between the groups. After the surgery, PFO patients experienced significant reductions in headache frequency and severity.
However, while their headaches improved, other migraine symptoms didn't change significantly. Overall, the surgery showed promise in alleviating migraines associated with PFO.
We found notable differences in certain metabolites like acetylcarnitine and dopamine between the groups. After the surgery, PFO patients experienced significant reductions in headache frequency and severity.
However, while their headaches improved, other migraine symptoms didn't change significantly. Overall, the surgery showed promise in alleviating migraines associated with PFO.
Read More
2
We conducted a robust study comparing acetyl-l-carnitine to a placebo for preventing migraines.
In a triple-blind, crossover design, 72 participants aged 18-65 received either the treatment or placebo for 12 weeks.
Unfortunately, our findings showed no significant differences in headache days between the two groups, meaning acetyl-l-carnitine did not prove effective as a preventive measure for migraines.
In a triple-blind, crossover design, 72 participants aged 18-65 received either the treatment or placebo for 12 weeks.
Unfortunately, our findings showed no significant differences in headache days between the two groups, meaning acetyl-l-carnitine did not prove effective as a preventive measure for migraines.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 4 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
10
Migraine relief
Excellent product; I'm very pleased with my purchase. These capsules are easy to swallow without tasting them. Previously, I used a brand with large, chalky, and odorous pills. While these capsules do have a slight smell, you can take them before noticing it, and they are far less pungent than the last brand. NAC has numerous health benefits (look up NAC and glycine!), but the most significant for me is its apparent elimination of my near migraine-level headaches. Good packaging.
Read More
7.5
Notable improvements
3 people found this helpful
We frequently host the entire family. Acetyl-L-Carnitine is the best form for absorption. A teenager with disabilities and migraines takes this supplement along with a basic protocol, and the improvements are noticeable over the year.
Read More
6
Helps migraines
2 people found this helpful
It was recommended to strengthen the brain's blood vessels. My acupuncturist suggested this to help counteract the debilitating effects of frequent migraines. It appears to work, but it's difficult to ascertain.
Read More
2
Energy boost
The product is okay for me, although it does trigger migraines. On the positive side, it provides energy, as many reviews suggest. When I'm utterly drained, the pill is quite helpful. However, I can only take it every two days; if I take it daily, I end up with a strong migraine. I've experimented with different methods of taking it because I appreciate the effect of the medication, yet the migraines persist.
Read More
Frequently Asked Questions
10
Migraine relief
Excellent product; I'm very pleased with my purchase. These capsules are easy to swallow without tasting them. Previously, I used a brand with large, chalky, and odorous pills. While these capsules do have a slight smell, you can take them before noticing it, and they are far less pungent than the last brand. NAC has numerous health benefits (look up NAC and glycine!), but the most significant for me is its apparent elimination of my near migraine-level headaches. Good packaging.
2
Energy boost
The product is okay for me, although it does trigger migraines. On the positive side, it provides energy, as many reviews suggest. When I'm utterly drained, the pill is quite helpful. However, I can only take it every two days; if I take it daily, I end up with a strong migraine. I've experimented with different methods of taking it because I appreciate the effect of the medication, yet the migraines persist.
7.5
Notable improvements
3 people found this helpful
We frequently host the entire family. Acetyl-L-Carnitine is the best form for absorption. A teenager with disabilities and migraines takes this supplement along with a basic protocol, and the improvements are noticeable over the year.
References
- Tuerxun P, Liu J, Aisaiti A, Shen G, Gong P, et al. Preliminary exploration of metabolomics mechanisms in patients with patent foramen ovale and migraine. J Oral Facial Pain Headache. 2024;38:111. 10.22514/jofph.2024.044
- Hagen K, Brenner E, Linde M, Gravdahl GB, Tronvik EA, et al. Acetyl-l-carnitine versus placebo for migraine prophylaxis: A randomized, triple-blind, crossover study. Cephalalgia. 2015;35:987. 10.1177/0333102414566817
