' 
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 6 Reviews
8.7
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Lactoferrin (as Apolactoferrin)
250 mg
†
Top Medical Research Studies
8
Lactoferrin enhances osteoblast activity
Lactoferrin promotes the autophagy activity during osteoblast formation via BCL2-Beclin1 signaling.
Directly addresses osteoporosis treatment
We explored how lactoferrin, a key component found in milk, plays a role in promoting osteoblast formation, which is crucial for preventing and treating osteoporosis. Our investigation looked at the effects of lactoferrin on the activity of primary osteoblasts—cells responsible for bone formation.
Our findings revealed that lactoferrin enhances the autophagy activity of these cells, a process that helps with cellular maintenance and function. We observed that lactoferrin impacts the BCL2 protein level in osteoblasts, which is connected to how autophagy is regulated. By increasing lactoferrin, we noted a decrease in BCL2 expression and its interaction with Beclin1, a protein needed for autophagy.
Ultimately, we learned that when BCL2 was overexpressed or Beclin1 was silenced, the beneficial effects of lactoferrin on autophagy and important osteogenic parameters were reversed. This suggests that lactoferrin may provide significant support for bone health by enhancing a specific pathway in osteoblast function, making it a promising candidate for osteoporosis treatment.
Our findings revealed that lactoferrin enhances the autophagy activity of these cells, a process that helps with cellular maintenance and function. We observed that lactoferrin impacts the BCL2 protein level in osteoblasts, which is connected to how autophagy is regulated. By increasing lactoferrin, we noted a decrease in BCL2 expression and its interaction with Beclin1, a protein needed for autophagy.
Ultimately, we learned that when BCL2 was overexpressed or Beclin1 was silenced, the beneficial effects of lactoferrin on autophagy and important osteogenic parameters were reversed. This suggests that lactoferrin may provide significant support for bone health by enhancing a specific pathway in osteoblast function, making it a promising candidate for osteoporosis treatment.
Read More
8
Lactoferrin shows promise for osteoporosis
The role of lactoferrin in bone remodeling: evaluation of its potential in targeted delivery and treatment of metabolic bone diseases and orthopedic conditions.
Study relevant to osteoporosis treatment
We explored how lactoferrin (Lf) could impact osteoporosis, a condition characterized by weakened bones. The research highlights Lf's significant role in bone remodeling by influencing the activity of various cells involved in bone health, like osteoblasts, osteoclasts, and chondrocytes.
Our findings indicate that Lf can stimulate bone formation while reducing bone resorption. This is crucial for reversing the effects of osteoporosis, where bone loss is prevalent. We observed that Lf enhances the function and growth of osteoblasts—cells responsible for building bone—while inhibiting the activity of osteoclasts, which break down bone.
Additionally, studies have shown that Lf may help in repairing fractures more efficiently. However, because Lf is quite large, ensuring sufficient delivery to the bones can be a challenge. This suggests that while Lf has promising benefits, strategies to improve its bioavailability are necessary to maximize its effects in treating osteoporosis. Overall, Lf appears to be an exciting avenue for research in bone health, specifically for those struggling with osteoporosis.
Our findings indicate that Lf can stimulate bone formation while reducing bone resorption. This is crucial for reversing the effects of osteoporosis, where bone loss is prevalent. We observed that Lf enhances the function and growth of osteoblasts—cells responsible for building bone—while inhibiting the activity of osteoclasts, which break down bone.
Additionally, studies have shown that Lf may help in repairing fractures more efficiently. However, because Lf is quite large, ensuring sufficient delivery to the bones can be a challenge. This suggests that while Lf has promising benefits, strategies to improve its bioavailability are necessary to maximize its effects in treating osteoporosis. Overall, Lf appears to be an exciting avenue for research in bone health, specifically for those struggling with osteoporosis.
Read More
Most Useful Reviews
9.5
Antibacterial properties
Lactoferrin is a crucial protein found in breast milk that aids in iron absorption and possesses antibacterial properties. It combats pathogenic bacteria and is beneficial for fighting herpes viruses and preventing osteoporosis. I give my child one capsule daily, and I’ve found the Jarrow supplement to be the most effective in terms of price and quality. It’s proven to work, and I highly recommend it.
Read More
9.5
Reduces risk
This product has been great for helping reduce my risk of osteoporosis, and the price is reasonable too.
Read More
9.5
Bone strengthening
I bought this product for its bone health benefits. It aids osteoporosis by helping calcium absorption into the bones and prevents calcium loss. Hence, it naturally strengthens the bones when consuming calcium-rich foods.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
- All Researches
8
Lactoferrin shows promise for osteoporosis
The role of lactoferrin in bone remodeling: evaluation of its potential in targeted delivery and treatment of metabolic bone diseases and orthopedic conditions.
Study relevant to osteoporosis treatment
We explored how lactoferrin (Lf) could impact osteoporosis, a condition characterized by weakened bones. The research highlights Lf's significant role in bone remodeling by influencing the activity of various cells involved in bone health, like osteoblasts, osteoclasts, and chondrocytes.
Our findings indicate that Lf can stimulate bone formation while reducing bone resorption. This is crucial for reversing the effects of osteoporosis, where bone loss is prevalent. We observed that Lf enhances the function and growth of osteoblasts—cells responsible for building bone—while inhibiting the activity of osteoclasts, which break down bone.
Additionally, studies have shown that Lf may help in repairing fractures more efficiently. However, because Lf is quite large, ensuring sufficient delivery to the bones can be a challenge. This suggests that while Lf has promising benefits, strategies to improve its bioavailability are necessary to maximize its effects in treating osteoporosis. Overall, Lf appears to be an exciting avenue for research in bone health, specifically for those struggling with osteoporosis.
Our findings indicate that Lf can stimulate bone formation while reducing bone resorption. This is crucial for reversing the effects of osteoporosis, where bone loss is prevalent. We observed that Lf enhances the function and growth of osteoblasts—cells responsible for building bone—while inhibiting the activity of osteoclasts, which break down bone.
Additionally, studies have shown that Lf may help in repairing fractures more efficiently. However, because Lf is quite large, ensuring sufficient delivery to the bones can be a challenge. This suggests that while Lf has promising benefits, strategies to improve its bioavailability are necessary to maximize its effects in treating osteoporosis. Overall, Lf appears to be an exciting avenue for research in bone health, specifically for those struggling with osteoporosis.
Read More
8
Lactoferrin enhances osteoblast activity
Lactoferrin promotes the autophagy activity during osteoblast formation via BCL2-Beclin1 signaling.
Directly addresses osteoporosis treatment
We explored how lactoferrin, a key component found in milk, plays a role in promoting osteoblast formation, which is crucial for preventing and treating osteoporosis. Our investigation looked at the effects of lactoferrin on the activity of primary osteoblasts—cells responsible for bone formation.
Our findings revealed that lactoferrin enhances the autophagy activity of these cells, a process that helps with cellular maintenance and function. We observed that lactoferrin impacts the BCL2 protein level in osteoblasts, which is connected to how autophagy is regulated. By increasing lactoferrin, we noted a decrease in BCL2 expression and its interaction with Beclin1, a protein needed for autophagy.
Ultimately, we learned that when BCL2 was overexpressed or Beclin1 was silenced, the beneficial effects of lactoferrin on autophagy and important osteogenic parameters were reversed. This suggests that lactoferrin may provide significant support for bone health by enhancing a specific pathway in osteoblast function, making it a promising candidate for osteoporosis treatment.
Our findings revealed that lactoferrin enhances the autophagy activity of these cells, a process that helps with cellular maintenance and function. We observed that lactoferrin impacts the BCL2 protein level in osteoblasts, which is connected to how autophagy is regulated. By increasing lactoferrin, we noted a decrease in BCL2 expression and its interaction with Beclin1, a protein needed for autophagy.
Ultimately, we learned that when BCL2 was overexpressed or Beclin1 was silenced, the beneficial effects of lactoferrin on autophagy and important osteogenic parameters were reversed. This suggests that lactoferrin may provide significant support for bone health by enhancing a specific pathway in osteoblast function, making it a promising candidate for osteoporosis treatment.
Read More
User Reviews
USERS' SCORE
Good
Based on 6 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Antibacterial properties
Lactoferrin is a crucial protein found in breast milk that aids in iron absorption and possesses antibacterial properties. It combats pathogenic bacteria and is beneficial for fighting herpes viruses and preventing osteoporosis. I give my child one capsule daily, and I’ve found the Jarrow supplement to be the most effective in terms of price and quality. It’s proven to work, and I highly recommend it.
Read More
9.5
Reduces risk
This product has been great for helping reduce my risk of osteoporosis, and the price is reasonable too.
9.5
Bone strengthening
I bought this product for its bone health benefits. It aids osteoporosis by helping calcium absorption into the bones and prevents calcium loss. Hence, it naturally strengthens the bones when consuming calcium-rich foods.
6.8
Boosts immunity
Since starting lactoferrin, I have noticed that it helps boost immunity, enhances the intestinal environment, and could prevent osteoporosis. Although it has only been a few weeks, I'm uncertain about its full effectiveness. Nevertheless, I'd like to continue taking it for now.
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8
Good effects
I consume it because it helps with osteoporosis, and I hope it will have positive effects.
