We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Read More
4
Magnesium shows limited sleep benefits
Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis.
We explored the effects of magnesium supplementation on insomnia in older adults through a systematic review and meta-analysis. Our investigation included several studies that compared magnesium with a placebo or no treatment.
We found three randomized control trials involving 151 older adults across three countries. The pooled results indicated that individuals taking magnesium had a notable decrease in sleep onset latency, averaging a reduction of 17.36 minutes compared to those on placebo. However, the improvement in total sleep time, which increased by 16.06 minutes in the magnesium group, did not reach statistical significance.
Despite these findings, we must emphasize that the overall quality of the research is below standards necessary for making firm recommendations. All studies reviewed showed a moderate to high risk of bias, and the evidence quality ranged from low to very low. Nonetheless, magnesium is an affordable and widely accessible option for those struggling with insomnia symptoms, suggesting it may be a reasonable consideration for some older adults.
Read More
8
Magnesium may reduce daytime sleepiness
Magnesium Intake and Sleep Disorder Symptoms: Findings from the Jiangsu Nutrition Study of Chinese Adults at Five-Year Follow-Up.
We set out to explore how dietary magnesium might impact symptoms of insomnia, such as falling asleep during the day and snoring at night. Our study included a significant sample of 1,487 adults from the Jiangsu Nutrition Study, which allowed us to gather valuable information about their magnesium intake and sleep experiences. Over five years, we assessed participants' magnesium consumption through detailed food records and later examined their sleep patterns via a questionnaire.
Our findings revealed that the average magnesium intake among participants was 332.5 mg per day. Interestingly, we found that around 5.3% reported falling asleep during the day, 13.2% faced daytime sleepiness, and 35.7% experienced snoring at night. Rising through the quartiles of magnesium intake, we observed a promising decrease in the chance of women experiencing daytime falling asleep; however, this effect wasn’t mirrored in men. It’s crucial to note that we didn’t find significant associations between magnesium intake and daytime sleepiness or night snoring for either gender.
Overall, it seems that dietary magnesium might offer long-term benefits in reducing daytime sleepiness in women, while more research could clarify its effects on other symptoms. This makes magnesium an interesting dietary consideration for those seeking to improve their sleep quality.
Read More
Most Useful Reviews
9
Insomnia relief
216 people found this helpful
It effectively soothes nervous disorders. After a month of use, my insomnia has vanished, and I find it much easier to fall asleep in the evenings.
Read More
9
Helps anxiety symptoms
25 people found this helpful
With bipolar disorder causing phases of reduced sleep needs, I have fibromyalgia, leading to insomnia. My doctor won't prescribe sleep medications, but I've found several effective supplements that help me sleep well. This product is a miracle supplement that aids not only in sleeping but also in alleviating anxiety during mania phases without adverse side effects.
Read More
9
Improves sleep quality
13 people found this helpful
Initially doubtful due to mixed reviews, I found this supplement positively effective. I suffer from insomnia, finding it hard to fall and stay asleep. Taking it at night has allowed me to sleep soundly, waking rested. Although I have a sensitive stomach, this product didn't cause any issues. I recommend giving it a try; it genuinely brings results!
We explored the potential benefits of a supplement containing magnesium, melatonin, and vitamin B complex in treating insomnia. The study involved 60 patients diagnosed with insomnia, who were divided into a study group and a control group. Over three months, the study group received a daily dose of the supplement, while the control group did not receive it.
At the start, both groups had similar levels of insomnia, indicated by their scores on the Athens insomnia scale. However, after three months of supplementation, the study group showed a significant improvement, with their insomnia scores decreasing, indicating mild insomnia. In contrast, the control group’s scores remained stable, suggesting they continued to experience moderate insomnia.
Although magnesium was part of the supplement, the study design makes it challenging to isolate its specific effects on insomnia. Nevertheless, we observed that combining magnesium with melatonin and vitamin B complex potentially enhances sleep quality for those struggling with insomnia.
Read More
9
Magnesium improves elderly insomnia
The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Read More
9
Magnesium may aid sleep quality
The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial.
We conducted a double-blind, placebo-controlled clinical trial in a long-term care facility in Italy to explore whether nightly doses of melatonin, magnesium, and zinc could benefit residents suffering from primary insomnia. Our study involved 43 participants, who were either given a combined supplement of these nutrients or a placebo for eight weeks.
The primary objective was to measure sleep quality using the Pittsburgh Sleep Quality Index, while we also considered secondary indicators like daytime sleepiness and overall quality of life. The results revealed that the combined approach of melatonin, magnesium, and zinc appeared to improve both sleep and quality of life for residents struggling with insomnia.
However, since magnesium was tested alongside two other supplements, we cannot clearly attribute the benefits directly to magnesium alone. Overall, the findings suggest a positive effect on sleep quality and well-being for long-term care residents dealing with insomnia, but we must be cautious in isolating each nutrient's individual effectiveness.
Read More
8
Magnesium improves insomnia in diabetes
Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
We conducted a randomized controlled trial focusing on individuals with diabetes who struggle with insomnia. Over two months, we examined the effects of magnesium and potassium supplementation on sleep quality and hormone levels. Our study included 320 patients, and after follow-up, 290 patients completed the trial. We assessed insomnia severity using the Insomnia Severity Index and analyzed changes in melatonin and cortisol levels, which are key sleep hormones.
Our findings indicated that magnesium supplementation—whether alone or in combination with potassium—had a notable positive impact. Participants who received magnesium and potassium demonstrated significant improvements in both insomnia severity and sleep hormone levels. It was exciting to see how these supplements could enhance sleep duration and quality in those facing the dual challenges of insomnia and diabetes.
Although the combination of magnesium and potassium was effective, we recognize that this limits a clear assessment of magnesium's isolated effects. Nevertheless, our research adds valuable insights on how these minerals may play a role in managing insomnia among diabetic patients.
Read More
8
Magnesium may aid post-surgery insomnia
Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial.
We conducted a study to explore how magnesium affects insomnia in patients undergoing lumbar fixation surgery. Our research involved 80 participants, divided into two groups: one received conventional general anesthesia supplemented with magnesium sulfate, while the other had standard anesthesia without magnesium.
We assessed various factors, including insomnia severity using the Insomnia Severity Index and post-operative delirium through the Memorial Delirium Assessment Scale. Interestingly, our findings indicated a significant relationship between the administration of magnesium and reduced instances of post-operative insomnia.
This suggests that magnesium may be beneficial in easing sleep disturbances experienced by some patients after surgery. However, we also noted variations due to other factors like pain and depression, which could influence the overall results.
While the relationship is promising, it’s essential to recognize that there may be multiple factors at play that contribute to insomnia post-surgery. Overall, our evaluation presents magnesium as a potentially helpful option for enhancing sleep quality in these patients.
It effectively soothes nervous disorders. After a month of use, my insomnia has vanished, and I find it much easier to fall asleep in the evenings.
Read More
9
Helps anxiety symptoms
25 people found this helpful
With bipolar disorder causing phases of reduced sleep needs, I have fibromyalgia, leading to insomnia. My doctor won't prescribe sleep medications, but I've found several effective supplements that help me sleep well. This product is a miracle supplement that aids not only in sleeping but also in alleviating anxiety during mania phases without adverse side effects.
Read More
9
Improves sleep quality
13 people found this helpful
Initially doubtful due to mixed reviews, I found this supplement positively effective. I suffer from insomnia, finding it hard to fall and stay asleep. Taking it at night has allowed me to sleep soundly, waking rested. Although I have a sensitive stomach, this product didn't cause any issues. I recommend giving it a try; it genuinely brings results!
Read More
9
Eases onset insomnia
8 people found this helpful
MagMind helps calm my mind and allows me to fall asleep easily. Unlike melatonin, I rise feeling clear-headed and in a better mood. As a lifelong sufferer of onset insomnia, this product has been more effective than any other sleep aid I've tried, including prescription drugs.
Read More
10
Effective magnesium
3 people found this helpful
This magnesium is one of the most effective for alleviating insomnia and seizures. It acts like a proper sleeping aid—within an hour, it pulls you to sleep naturally, unlike many sleeping pills. Although I wish the dosage were lower with fewer capsules required, it's still a good product.
Insomnia is a common sleep disorder characterized by the inability to fall asleep, stay asleep, or wake up too early and not be able to go back to sleep. Individuals experiencing insomnia may find that it affects their daytime functioning, leading to issues such as fatigue, mood disturbances, and difficulty concentrating. Insomnia can be classified into two main types: acute insomnia, which lasts for a short period often triggered by stress or life changes, and chronic insomnia, which occurs at least three times a week for three months or longer, and may require more in-depth evaluation and treatment.
Numerous factors can contribute to insomnia, including stress, anxiety, poor sleep habits, medical conditions, and the use of certain medications. Treatment for insomnia typically involves a combination of lifestyle changes, cognitive behavioral therapy for insomnia (CBT-I), and sometimes medication. Establishing a consistent sleep routine, creating a comfortable sleep environment, and practicing relaxation techniques can help improve sleep quality. If insomnia persists, it is advisable to consult a healthcare professional for proper diagnosis and customized treatment options.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium is often touted as a natural remedy for improving sleep quality and managing insomnia. This essential mineral plays a crucial role in various bodily functions, including the regulation of neurotransmitters that send signals throughout the nervous system and brain. Some studies suggest that magnesium may assist in promoting relaxation by helping to regulate melatonin, a hormone responsible for sleep-wake cycles. Additionally, it may help reduce anxiety and stress, which are common culprits of sleep disturbances.
While many people report improved sleep after incorporating magnesium supplements or magnesium-rich foods—like leafy greens, nuts, and whole grains—into their diets, the scientific evidence is mixed. More research is needed to definitively establish its effectiveness in treating insomnia. If you're considering magnesium supplements, it's always best to consult with a healthcare professional to determine the appropriate dosage and ensure that it won’t interact with any medications you may be taking. Overall, while magnesium may offer some benefits for sleep, it is most effective when used as part of a comprehensive approach to improving sleep hygiene.
Based on user reviews, the timeline for experiencing results from this supplement for insomnia can vary significantly. Some users report almost immediate effects, claiming that they feel the calming benefits within an hour after taking the supplement, effectively helping them to fall asleep naturally (Read Review). Others, however, indicate that it may take a month or more to fully alleviate their insomnia issues, with one user noting that after using the product for a month, their insomnia had vanished (Read Review).
In general, we see that while immediate benefits can occur for some, the overall time to achieve a stable improvement in sleep quality might take a few weeks of consistent use. Users recommend integrating the supplement into a broader routine for optimal results, particularly for those struggling with anxiety-related insomnia, which may require additional time to notice significant improvements (Read Review).
Magnesium supplementation has shown promising potential in aiding those suffering from insomnia, with several studies supporting its effectiveness across different populations. A randomized controlled trial involving diabetic patients demonstrated that magnesium, either alone or combined with potassium, led to significant improvements in insomnia severity and sleep hormone levels, underscoring its potential role in enhancing sleep quality [1]. Additionally, a systematic review highlighted that out of 15 studies examined, five showed improved sleep quality with magnesium supplementation, although results were mixed overall [3].
Other specific studies reinforce magnesium's benefits, particularly among older adults and those recovering from surgical procedures. For instance, a clinical trial indicated significant improvements in sleep quality among elderly participants receiving magnesium compared to a placebo, pointing towards its utility in managing insomnia in this demographic [8]. However, it's essential to note that while findings are encouraging, many studies have limitations that necessitate cautious interpretation. More comprehensive and larger-scale studies would help clarify the precise role of magnesium and optimize its application in treating insomnia.
Based on user reviews, many individuals have reported significant improvements in their insomnia symptoms after using the supplement. A notable number of users described complete relief from insomnia, with one stating, "After a month of use, my insomnia has vanished" (Read Review). Others have found that they can fall asleep much more easily, with some noting the calming effects kicking in within an hour of ingestion (Read Review). Additionally, users experiencing insomnia related to anxiety revealed that the supplement helped eliminate both their wakefulness during the night and anxiety symptoms (Read Review).
Overall, users have shared a mix of experiences regarding sleep quality, with several claiming to enjoy deeper and more restorative sleep after incorporating the supplement into their routine (Read Review). Many reported improvements in daytime alertness and energy levels as a bonus, indicating a multifaceted benefit to those struggling with insomnia (Read Review). However, it's important to note that individual experiences can vary, and results may not be universal, particularly for those with more severe insomnia or anxiety levels (Read Review).
Based on user reviews, many individuals have reported positive experiences when combining this supplement with other products to manage insomnia. One user highlighted their success using it alongside herbal cortisol-reducing supplements and Mg Theanine, stating that the combination allowed them to achieve better sleep quality when traditional sleeping pills like Ambien had failed (Read Review). Another user noted that they experienced significant improvements in sleep and were able to fall back asleep more easily when integrating additional supplements into their routine, suggesting that a multifaceted approach can enhance overall effectiveness for those struggling with insomnia (Read Review).
While many users praised the supplement for alleviating insomnia on its own, they also indicated that its efficacy could be further enhanced when used in combination with other supportive products. However, some users cautioned that results may vary, emphasizing that those with severe anxiety should consider this supplement as part of a broader routine rather than expecting it to deliver miraculous results alone (Read Review). Overall, the general consensus appears to be that users have found greater sleep success when this supplement is incorporated alongside other targeted supplements aimed at anxiety reduction and overall relaxation.
According to recent studies, magnesium has shown promise as a treatment for insomnia, particularly in specific populations such as older adults and individuals undergoing surgery. One notable study found that a daily dose of 500 mg of magnesium for eight weeks led to significant improvements in sleep quality and insomnia severity among elderly participants [8]. Another study indicated that magnesium supplementation may help reduce post-operative insomnia, though the exact dosage specifics weren't highlighted in that trial [2].
Furthermore, the general trend across multiple studies suggests that magnesium supplementation could be beneficial, especially for individuals with low initial magnesium levels. While various studies have noted improvements, the optimal dose may vary, and more research is necessary to establish definitive guidelines. If you’re looking to incorporate magnesium into your sleep routine, considering a dosage of around 300-500 mg may be beneficial, but it's always a good idea to consult with a healthcare provider for personalized advice [3].
10
Effective magnesium
3 people found this helpful
This magnesium is one of the most effective for alleviating insomnia and seizures. It acts like a proper sleeping aid—within an hour, it pulls you to sleep naturally, unlike many sleeping pills. Although I wish the dosage were lower with fewer capsules required, it's still a good product.
9
Insomnia relief
216 people found this helpful
It effectively soothes nervous disorders. After a month of use, my insomnia has vanished, and I find it much easier to fall asleep in the evenings.
9
Anxiety and insomnia relief
3 people found this helpful
Upon starting this, my awakenings and anxiety disappeared. This is highly recommended for those with insomnia related to anxiety.
7.5
Improved sleep quality
Improved sleep quality. I started taking these on the advice of Dr Peter Attia's book, "Outlive," to enhance my sleep, as I’ve struggled with insomnia for a long time. I’ve noticed a significant improvement when combined with a few other supplements. I achieve deeper sleep and find it much easier to fall back asleep after waking in the night. Highly recommend.
9
Noticeable improvement
A brilliant solution for sleep problems! I bought this product twice already and will definitely include it in my regular supplement routine. I’ve been struggling with insomnia and "brain fog," so I decided to give this a go after hearing about it. I've experienced a noticeable improvement in sleep quality and daytime alertness. I used it alongside other herbal cortisol-reducing supplements and Mg Theanine, and it worked wonders, enabling me to sleep when prescription drugs like Ambien failed.
4
Mildly helpful
If you have serious anxiety and expect miraculous results, this may not work. The benefits of this magnesium seem overstated. It won't necessarily cure insomnia but can help calm the body and mind; I recommend it as part of a broader routine.
8
Magnesium improves insomnia in diabetes
Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
We conducted a randomized controlled trial focusing on individuals with diabetes who struggle with insomnia. Over two months, we examined the effects of magnesium and potassium supplementation on sleep quality and hormone levels. Our study included 320 patients, and after follow-up, 290 patients completed the trial. We assessed insomnia severity using the Insomnia Severity Index and analyzed changes in melatonin and cortisol levels, which are key sleep hormones.
Our findings indicated that magnesium supplementation—whether alone or in combination with potassium—had a notable positive impact. Participants who received magnesium and potassium demonstrated significant improvements in both insomnia severity and sleep hormone levels. It was exciting to see how these supplements could enhance sleep duration and quality in those facing the dual challenges of insomnia and diabetes.
Although the combination of magnesium and potassium was effective, we recognize that this limits a clear assessment of magnesium's isolated effects. Nevertheless, our research adds valuable insights on how these minerals may play a role in managing insomnia among diabetic patients.
7
Magnesium may improve insomnia
Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review.
We examined the potential benefits of magnesium supplements for improving sleep quality through a detailed analysis of existing clinical studies. Our systematic review focused specifically on trials investigating how magnesium affects insomnia, which have gained popularity among people seeking natural remedies for sleep problems.
A total of 15 relevant studies were reviewed. Among these, eight studies looked specifically at sleep-related outcomes, often employing the Pittsburgh Sleep Quality Index (PSQI) to measure improvements. The results were promising—five out of the eight studies indicated that magnesium supplementation led to better sleep quality.
However, it's important to note that not all studies observed benefits; two showed no significant improvements, and one provided mixed results. Many of these studies varied in the dosage, type of magnesium used, and overall participant numbers, which made it challenging to draw firm conclusions. Still, the general trend suggests that magnesium could indeed be helpful, especially for those who start with low magnesium levels.
Ultimately, while the findings lean towards positive, further large-scale, randomized trials are necessary to confirm the effectiveness of specific magnesium formulations and dosages in treating insomnia. We take these outcomes seriously, considering them a first step towards understanding how this mineral can help those struggling with sleep issues.
9
Magnesium improves elderly insomnia
The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
8
Magnesium may aid post-surgery insomnia
Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial.
We conducted a study to explore how magnesium affects insomnia in patients undergoing lumbar fixation surgery. Our research involved 80 participants, divided into two groups: one received conventional general anesthesia supplemented with magnesium sulfate, while the other had standard anesthesia without magnesium.
We assessed various factors, including insomnia severity using the Insomnia Severity Index and post-operative delirium through the Memorial Delirium Assessment Scale. Interestingly, our findings indicated a significant relationship between the administration of magnesium and reduced instances of post-operative insomnia.
This suggests that magnesium may be beneficial in easing sleep disturbances experienced by some patients after surgery. However, we also noted variations due to other factors like pain and depression, which could influence the overall results.
While the relationship is promising, it’s essential to recognize that there may be multiple factors at play that contribute to insomnia post-surgery. Overall, our evaluation presents magnesium as a potentially helpful option for enhancing sleep quality in these patients.
References
Khalid S, Bashir S, Mehboob R, Anwar T, Ali M, et al. Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus. Front Endocrinol (Lausanne). 2024;15:1370733. 10.3389/fendo.2024.1370733
Fathy W, Hussein M, Elanwar R, Elmoutaz H, Abdelsadek DA, et al. Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial. BMC Anesthesiol. 2024;24:289. 10.1186/s12871-024-02579-6
Rawji A, Peltier MR, Mourtzanakis K, Awan S, Rana J, et al. Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review. Cureus. 2024;16:e59317. 10.7759/cureus.59317
Mah J, Pitre T. Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis. BMC Complement Med Ther. 2021;21:125. 10.1186/s12906-021-03297-z
Djokic G, Vojvodić P, Korcok D, Agic A, Rankovic A, et al. The Effects of Magnesium - Melatonin - Vit B Complex Supplementation in Treatment of Insomnia. Open Access Maced J Med Sci. 2019;7:3101. 10.3889/oamjms.2019.771
Cao Y, Zhen S, Taylor AW, Appleton S, Atlantis E, et al. Magnesium Intake and Sleep Disorder Symptoms: Findings from the Jiangsu Nutrition Study of Chinese Adults at Five-Year Follow-Up. Nutrients. 2018;10. 10.3390/nu10101354
Scholey A, Benson S, Gibbs A, Perry N, Sarris J, et al. Exploring the Effect of Lactium™ and Zizyphus Complex on Sleep Quality: A Double-Blind, Randomized Placebo-Controlled Trial. Nutrients. 2017;9. 10.3390/nu9020154
Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, et al. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci. 2012;17:1161.
Rondanelli M, Opizzi A, Monteferrario F, Antoniello N, Manni R, et al. The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial. J Am Geriatr Soc. 2011;59:82. 10.1111/j.1532-5415.2010.03232.x
Mucci M, Carraro C, Mancino P, Monti M, Papadia LS, et al. Soy isoflavones, lactobacilli, Magnolia bark extract, vitamin D3 and calcium. Controlled clinical study in menopause. Minerva Ginecol. 2006;58:323.
Hornyak M, Haas P, Veit J, Gann H, Riemann D. Magnesium treatment of primary alcohol-dependent patients during subacute withdrawal: an open pilot study with polysomnography. Alcohol Clin Exp Res. 2004;28:1702.
Hornyak M, Voderholzer U, Hohagen F, Berger M, Riemann D. Magnesium therapy for periodic leg movements-related insomnia and restless legs syndrome: an open pilot study. Sleep. 1998;21:501.