Last update
5/25/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
USERS' SCORE
Good
Based on 5 Reviews
8.4
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Folate (400 mcg as (6S)-5-MTHF [(6S)-5-Methyltetrahydrofolate Glucosamine Salt)
680 mcg DFE‡
170%
Top Medical Research Studies
7
Liver abscess improvement inconclusive
We investigated how a rumen-protected folic acid (RPFA) supplement affects the health and performance of beef steers. This study used a randomized design with 180 Angus-crossbred steers divided into different treatment groups.
Although we observed that RPFA increased plasma folate levels and improved certain growth metrics, the findings on liver abscesses were less pronounced. The percentage of livers without abscesses showed a tendency to improve with lower RPFA doses, but no significant benefits overall were found.
It's essential to note that vitamin B12 levels were low across all treatments, which might have influenced the outcomes related to RPFA effectiveness.
Although we observed that RPFA increased plasma folate levels and improved certain growth metrics, the findings on liver abscesses were less pronounced. The percentage of livers without abscesses showed a tendency to improve with lower RPFA doses, but no significant benefits overall were found.
It's essential to note that vitamin B12 levels were low across all treatments, which might have influenced the outcomes related to RPFA effectiveness.
Read More
Most Useful Reviews
9
Discomfort alleviated
Excellent shape and effect. During ovulation, I experienced unpleasant sensations in my lower abdomen, feeling full. An ultrasound revealed an ovarian cyst. The gynaecologist suggested hormonal pills, but due to previous side effects, I chose not to follow this advice. I learned that folic acid could help, and after completing the course, the discomfort vanished, and my menstruation became more regular. I highly recommend it to women facing similar issues! There are no overdoses from methylfolate, and it seems to have no side effects, so I believe it can be taken without prior consultation.
Read More
9
Pregnancy achieved
Amazing! I had great results using it with the FH Pro supplement from iHerb while maintaining a healthy diet. I managed to get pregnant despite suffering from cysts and irregular periods.
Read More
9
Cysts resolved
Really amazing! The quality is very high. Folic acid is well-known for its benefits for women's health, especially during pregnancy and even for hair and nails. It's safe for pregnant women and is tasteless and odourless. The quantity lasts for two months with one pill daily. I combined it with myo-inositol, which helped me eliminate cysts. The package arrived well-protected. Thank you, iHerb.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 1 Research
7
- All Researches
7
Liver abscess improvement inconclusive
We investigated how a rumen-protected folic acid (RPFA) supplement affects the health and performance of beef steers. This study used a randomized design with 180 Angus-crossbred steers divided into different treatment groups.
Although we observed that RPFA increased plasma folate levels and improved certain growth metrics, the findings on liver abscesses were less pronounced. The percentage of livers without abscesses showed a tendency to improve with lower RPFA doses, but no significant benefits overall were found.
It's essential to note that vitamin B12 levels were low across all treatments, which might have influenced the outcomes related to RPFA effectiveness.
Although we observed that RPFA increased plasma folate levels and improved certain growth metrics, the findings on liver abscesses were less pronounced. The percentage of livers without abscesses showed a tendency to improve with lower RPFA doses, but no significant benefits overall were found.
It's essential to note that vitamin B12 levels were low across all treatments, which might have influenced the outcomes related to RPFA effectiveness.
Read More
User Reviews
USERS' SCORE
Good
Based on 5 Reviews
8.4
- All Reviews
- Positive Reviews
- Negative Reviews
9
Discomfort alleviated
Excellent shape and effect. During ovulation, I experienced unpleasant sensations in my lower abdomen, feeling full. An ultrasound revealed an ovarian cyst. The gynaecologist suggested hormonal pills, but due to previous side effects, I chose not to follow this advice. I learned that folic acid could help, and after completing the course, the discomfort vanished, and my menstruation became more regular. I highly recommend it to women facing similar issues! There are no overdoses from methylfolate, and it seems to have no side effects, so I believe it can be taken without prior consultation.
Read More
9
Pregnancy achieved
Amazing! I had great results using it with the FH Pro supplement from iHerb while maintaining a healthy diet. I managed to get pregnant despite suffering from cysts and irregular periods.
Read More
9
Cysts resolved
Really amazing! The quality is very high. Folic acid is well-known for its benefits for women's health, especially during pregnancy and even for hair and nails. It's safe for pregnant women and is tasteless and odourless. The quantity lasts for two months with one pill daily. I combined it with myo-inositol, which helped me eliminate cysts. The package arrived well-protected. Thank you, iHerb.
Read More
8
Cysts gone
He often describes it as a woman. Well, the cysts have passed, so the result is clear. The packaging is compact, and the composition is good; natural folic acid differs from the synthetic varieties found in pharmacies.
Read More
6
Effective treatment
Good methylfolate; it helps me significantly in treating cysts!
Read More
Frequently Asked Questions
9
Discomfort alleviated
Excellent shape and effect. During ovulation, I experienced unpleasant sensations in my lower abdomen, feeling full. An ultrasound revealed an ovarian cyst. The gynaecologist suggested hormonal pills, but due to previous side effects, I chose not to follow this advice. I learned that folic acid could help, and after completing the course, the discomfort vanished, and my menstruation became more regular. I highly recommend it to women facing similar issues! There are no overdoses from methylfolate, and it seems to have no side effects, so I believe it can be taken without prior consultation.
9
Pregnancy achieved
Amazing! I had great results using it with the FH Pro supplement from iHerb while maintaining a healthy diet. I managed to get pregnant despite suffering from cysts and irregular periods.
9
Cysts resolved
Really amazing! The quality is very high. Folic acid is well-known for its benefits for women's health, especially during pregnancy and even for hair and nails. It's safe for pregnant women and is tasteless and odourless. The quantity lasts for two months with one pill daily. I combined it with myo-inositol, which helped me eliminate cysts. The package arrived well-protected. Thank you, iHerb.
8
Cysts gone
He often describes it as a woman. Well, the cysts have passed, so the result is clear. The packaging is compact, and the composition is good; natural folic acid differs from the synthetic varieties found in pharmacies.
References
- Deters EL, Niedermayer EK, Genther-Schroeder ON, Blank CP, Carmichael RN, et al. Investigating the effects of a novel rumen-protected folic acid supplement on feedlot performance and carcass characteristics of beef steers. Transl Anim Sci. 2021;5:txab093. 10.1093/tas/txab093
