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SCIENTIFIC SCORE
Questionable
Based on 6 Researches
6.8
USERS' SCORE
Good
Based on 1 Reviews
8.5
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin B₁₂ (as Methylcobalamin)
1,000 mcg
41,667%
Top Medical Research Studies
7
Vitamin B12 and lymphoma association
Circulating levels of vitamins and risk of lymphoma: insights from a two-sample Mendelian randomization.
Significant link established, further research needed
We aimed to understand how levels of vitamin B12 might influence the risk of developing lymphoma, a type of cancer that affects the lymphatic system. Using data from comprehensive genome-wide association studies, we assessed the potential genetic links between circulating vitamin levels and lymphoma.
Our analysis particularly focused on vitamin B12 along with other vitamins, utilizing robust methods to ensure reliable results. We discovered that higher levels of vitamin B12 showed a noticeable association with a lower risk of lymphoma, indicating that it might play a beneficial role in cancer prevention. Interestingly, we also found similar results for folic acid, suggesting that these vitamins could have important implications for lymphoma risk overall.
However, it's essential to note that while our findings are promising, the evidence isn't definitive. Further research is needed to explore these relationships in greater depth and to understand the mechanisms behind them. Understanding how vitamins like B12 affect cancer could lead to better preventive strategies in the future.
Our analysis particularly focused on vitamin B12 along with other vitamins, utilizing robust methods to ensure reliable results. We discovered that higher levels of vitamin B12 showed a noticeable association with a lower risk of lymphoma, indicating that it might play a beneficial role in cancer prevention. Interestingly, we also found similar results for folic acid, suggesting that these vitamins could have important implications for lymphoma risk overall.
However, it's essential to note that while our findings are promising, the evidence isn't definitive. Further research is needed to explore these relationships in greater depth and to understand the mechanisms behind them. Understanding how vitamins like B12 affect cancer could lead to better preventive strategies in the future.
Read More
8
Combining treatments reduces HPV positivity
Treatment with Epigallocatechin Gallate, Folic Acid, Vitamin B12, and Hyaluronic Acid Decreases HPV Positivity in Women Attending Regional Screening in Puglia.
Indicates value of combination therapy
We explored how vitamin B12, alongside other natural compounds, impacts HPV positivity in women at risk of cervical cancer. Our study involved 163 women who had either tested positive for HPV or had a history of HPV infections. They were divided into two groups: one group received a specific oral treatment containing vitamin B12 along with other ingredients for three months, while the other group underwent standard clinical monitoring.
After this period, we found that the group receiving the combination treatment showed a significant decrease in HPV positivity compared to the control group. Importantly, not only did vitamin B12 play a role in the treatment, but it was the combination of all four components—EGCG, folic acid, vitamin B12, and hyaluronic acid—that appeared particularly effective in improving the condition of their cervical health.
While vitamin B12's isolated effect on cancer isn't directly measurable from this study, we observed considerable improvements in cervical lesions as well, suggesting that this regimen may help manage HPV-related risks. This highlights the potential for natural treatments in women's health, particularly in reducing the burden of HPV, which is a critical concern for cancer prevention.
After this period, we found that the group receiving the combination treatment showed a significant decrease in HPV positivity compared to the control group. Importantly, not only did vitamin B12 play a role in the treatment, but it was the combination of all four components—EGCG, folic acid, vitamin B12, and hyaluronic acid—that appeared particularly effective in improving the condition of their cervical health.
While vitamin B12's isolated effect on cancer isn't directly measurable from this study, we observed considerable improvements in cervical lesions as well, suggesting that this regimen may help manage HPV-related risks. This highlights the potential for natural treatments in women's health, particularly in reducing the burden of HPV, which is a critical concern for cancer prevention.
Read More
7
Vitamin B12's role in CIPN
Is Functional Vitamin B12 Deficiency a Risk Factor for the Development of Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients?
Significant findings on CIPN risk
We aimed to explore how functional vitamin B12 deficiency might relate to chemotherapy-induced peripheral neuropathy (CIPN) in cancer patients. Our study involved 64 adults who were newly diagnosed with various cancers and were set to start their first chemotherapy cycle. We gathered data on vitamin B12 levels and associated metabolites both before treatment and after its completion.
After analyzing these results, we found that elevated levels of methylmalonic acid (MMA), indicating functional vitamin B12 deficiency, were linked to an increased risk of developing CIPN. This suggests that vitamin B12 plays a significant role in this context.
However, while our findings highlight the importance of monitoring vitamin B12 status in cancer patients undergoing chemotherapy, they also call for further research to investigate whether vitamin B12 therapy could help prevent or manage CIPN effectively. Our study points towards a potential avenue for improving patient care but is not a conclusive endorsement of vitamin B12 treatment yet.
After analyzing these results, we found that elevated levels of methylmalonic acid (MMA), indicating functional vitamin B12 deficiency, were linked to an increased risk of developing CIPN. This suggests that vitamin B12 plays a significant role in this context.
However, while our findings highlight the importance of monitoring vitamin B12 status in cancer patients undergoing chemotherapy, they also call for further research to investigate whether vitamin B12 therapy could help prevent or manage CIPN effectively. Our study points towards a potential avenue for improving patient care but is not a conclusive endorsement of vitamin B12 treatment yet.
Read More
Most Useful Reviews
8
Helpful for neuropathy
Great products that have been very beneficial for neuropathy resulting from cancer treatments.
Read More
Medical Researches
SCIENTIFIC SCORE
Questionable
Based on 6 Researches
6.8
8
Dendrobium improves oral mucositis
Effect of Dendrobium Officinale on Radioactive Oral Mucositis of Nasopharyngeal Carcinoma and Changes of Oral Microecology.
Limited isolated B12 benefits
We explored the effects of Dendrobium officinale, combined with vitamin B12, on patients suffering from oral mucositis due to radiotherapy for nasopharyngeal cancer. In a well-structured study conducted at Zhejiang Cancer Hospital, we involved sixty patients, dividing them into two groups. One group received Dendrobium tea alongside vitamin B12, while the other group was given vitamin B12 alone.
Our focus was to determine how this combination could help alleviate the harsh side effects of radiotherapy, particularly the inflammation and pain associated with oral mucositis. After a month of treatment, we evaluated several factors, such as salivary flow and levels of specific immune markers in the patients' blood and saliva.
Interestingly, we discovered that Dendrobium officinale showed potential in improving oral mucositis symptoms through better salivary gland function and modifications to the oral microbiome. Though vitamin B12 was part of the treatment, it wasn’t isolated in our findings. As a result, we cannot definitively speak about its specific benefits on its own without acknowledging the combined effects with Dendrobium.
Overall, our findings highlight the promise of Dendrobium officinale in addressing oral complications from cancer treatment, yet the role of vitamin B12 remains intertwined and less distinct in this context.
Our focus was to determine how this combination could help alleviate the harsh side effects of radiotherapy, particularly the inflammation and pain associated with oral mucositis. After a month of treatment, we evaluated several factors, such as salivary flow and levels of specific immune markers in the patients' blood and saliva.
Interestingly, we discovered that Dendrobium officinale showed potential in improving oral mucositis symptoms through better salivary gland function and modifications to the oral microbiome. Though vitamin B12 was part of the treatment, it wasn’t isolated in our findings. As a result, we cannot definitively speak about its specific benefits on its own without acknowledging the combined effects with Dendrobium.
Overall, our findings highlight the promise of Dendrobium officinale in addressing oral complications from cancer treatment, yet the role of vitamin B12 remains intertwined and less distinct in this context.
Read More
8
Combining treatments reduces HPV positivity
Treatment with Epigallocatechin Gallate, Folic Acid, Vitamin B12, and Hyaluronic Acid Decreases HPV Positivity in Women Attending Regional Screening in Puglia.
Indicates value of combination therapy
We explored how vitamin B12, alongside other natural compounds, impacts HPV positivity in women at risk of cervical cancer. Our study involved 163 women who had either tested positive for HPV or had a history of HPV infections. They were divided into two groups: one group received a specific oral treatment containing vitamin B12 along with other ingredients for three months, while the other group underwent standard clinical monitoring.
After this period, we found that the group receiving the combination treatment showed a significant decrease in HPV positivity compared to the control group. Importantly, not only did vitamin B12 play a role in the treatment, but it was the combination of all four components—EGCG, folic acid, vitamin B12, and hyaluronic acid—that appeared particularly effective in improving the condition of their cervical health.
While vitamin B12's isolated effect on cancer isn't directly measurable from this study, we observed considerable improvements in cervical lesions as well, suggesting that this regimen may help manage HPV-related risks. This highlights the potential for natural treatments in women's health, particularly in reducing the burden of HPV, which is a critical concern for cancer prevention.
After this period, we found that the group receiving the combination treatment showed a significant decrease in HPV positivity compared to the control group. Importantly, not only did vitamin B12 play a role in the treatment, but it was the combination of all four components—EGCG, folic acid, vitamin B12, and hyaluronic acid—that appeared particularly effective in improving the condition of their cervical health.
While vitamin B12's isolated effect on cancer isn't directly measurable from this study, we observed considerable improvements in cervical lesions as well, suggesting that this regimen may help manage HPV-related risks. This highlights the potential for natural treatments in women's health, particularly in reducing the burden of HPV, which is a critical concern for cancer prevention.
Read More
7
Vitamin B12's role in CIPN
Is Functional Vitamin B12 Deficiency a Risk Factor for the Development of Chemotherapy-Induced Peripheral Neuropathy in Cancer Patients?
Significant findings on CIPN risk
We aimed to explore how functional vitamin B12 deficiency might relate to chemotherapy-induced peripheral neuropathy (CIPN) in cancer patients. Our study involved 64 adults who were newly diagnosed with various cancers and were set to start their first chemotherapy cycle. We gathered data on vitamin B12 levels and associated metabolites both before treatment and after its completion.
After analyzing these results, we found that elevated levels of methylmalonic acid (MMA), indicating functional vitamin B12 deficiency, were linked to an increased risk of developing CIPN. This suggests that vitamin B12 plays a significant role in this context.
However, while our findings highlight the importance of monitoring vitamin B12 status in cancer patients undergoing chemotherapy, they also call for further research to investigate whether vitamin B12 therapy could help prevent or manage CIPN effectively. Our study points towards a potential avenue for improving patient care but is not a conclusive endorsement of vitamin B12 treatment yet.
After analyzing these results, we found that elevated levels of methylmalonic acid (MMA), indicating functional vitamin B12 deficiency, were linked to an increased risk of developing CIPN. This suggests that vitamin B12 plays a significant role in this context.
However, while our findings highlight the importance of monitoring vitamin B12 status in cancer patients undergoing chemotherapy, they also call for further research to investigate whether vitamin B12 therapy could help prevent or manage CIPN effectively. Our study points towards a potential avenue for improving patient care but is not a conclusive endorsement of vitamin B12 treatment yet.
Read More
7
Vitamin B12's uncertain cancer link
Dietary factors and the risk of gastric and colorectal cancers: A Mendelian randomization study.
Mixed findings on cancer risk
We examined how dietary factors, including vitamin B12, relate to the risk of gastric and colorectal cancers. Using a method called Mendelian randomization, we evaluated the impact of various macronutrients and micronutrients on cancer risk.
Our findings indicated that vitamin B12 levels could have an influential role in colorectal cancer risk, with genetically predicted B12 intake showing a significant association. Specifically, we noted that higher vitamin B12 levels correlated with an increased risk of colorectal cancer. Additionally, we observed that vitamin C also plays a role in reducing the risk of colorectal cancer.
However, we found no significant associations for vitamin B12 in gastric cancer, and the study highlighted that protein, carbohydrate, and sugar intake can also affect cancer risk. Overall, while vitamin B12 may be relevant, the evidence does not provide a clear benefit in cancer prevention or treatment and further research is essential to draw firmer conclusions.
Our findings indicated that vitamin B12 levels could have an influential role in colorectal cancer risk, with genetically predicted B12 intake showing a significant association. Specifically, we noted that higher vitamin B12 levels correlated with an increased risk of colorectal cancer. Additionally, we observed that vitamin C also plays a role in reducing the risk of colorectal cancer.
However, we found no significant associations for vitamin B12 in gastric cancer, and the study highlighted that protein, carbohydrate, and sugar intake can also affect cancer risk. Overall, while vitamin B12 may be relevant, the evidence does not provide a clear benefit in cancer prevention or treatment and further research is essential to draw firmer conclusions.
Read More
7
Vitamin B12 and lymphoma association
Circulating levels of vitamins and risk of lymphoma: insights from a two-sample Mendelian randomization.
Significant link established, further research needed
We aimed to understand how levels of vitamin B12 might influence the risk of developing lymphoma, a type of cancer that affects the lymphatic system. Using data from comprehensive genome-wide association studies, we assessed the potential genetic links between circulating vitamin levels and lymphoma.
Our analysis particularly focused on vitamin B12 along with other vitamins, utilizing robust methods to ensure reliable results. We discovered that higher levels of vitamin B12 showed a noticeable association with a lower risk of lymphoma, indicating that it might play a beneficial role in cancer prevention. Interestingly, we also found similar results for folic acid, suggesting that these vitamins could have important implications for lymphoma risk overall.
However, it's essential to note that while our findings are promising, the evidence isn't definitive. Further research is needed to explore these relationships in greater depth and to understand the mechanisms behind them. Understanding how vitamins like B12 affect cancer could lead to better preventive strategies in the future.
Our analysis particularly focused on vitamin B12 along with other vitamins, utilizing robust methods to ensure reliable results. We discovered that higher levels of vitamin B12 showed a noticeable association with a lower risk of lymphoma, indicating that it might play a beneficial role in cancer prevention. Interestingly, we also found similar results for folic acid, suggesting that these vitamins could have important implications for lymphoma risk overall.
However, it's essential to note that while our findings are promising, the evidence isn't definitive. Further research is needed to explore these relationships in greater depth and to understand the mechanisms behind them. Understanding how vitamins like B12 affect cancer could lead to better preventive strategies in the future.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Reviews
8.5
8
Helpful for neuropathy
Great products that have been very beneficial for neuropathy resulting from cancer treatments.
