'
SCIENTIFIC SCORE
Likely Ineffective
Based on 4 Researches
4.8
USERS' SCORE
Good
Based on 2 Reviews
8.6
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin B₁₂ (as Methylcobalamin)
1,000 mcg
41,667%

Top Medical Research Studies

7
Vitamin B12 and hypothyroid patients
A Study on Vitamin B12 Levels in Hypothyroid Patients Presenting to a Tertiary Care Teaching Hospital.
Direct relevance to hypothyroid treatment
We explored the connection between vitamin B12 deficiency and hypothyroidism through a focused study involving 100 hypothyroid patients. This research took place over a year and aimed to determine how common vitamin B12 deficiency is among these individuals and how it correlates with thyroid antibodies.

Our findings revealed that a significant 68% of the hypothyroid patients were vitamin B12 deficient. Interestingly, a large majority of these deficient patients were female, specifically 73.5%. Additionally, we noted that a high percentage of patients with elevated Anti TPO and Anti Thyroglobulin antibodies also had low vitamin B12 levels.

Although vitamin B12 deficiency was present in a notable portion of the hypothyroid population, we're careful to point out that the study does not state that vitamin B12 supplementation alone can fully alleviate hypothyroid symptoms. However, it suggests that addressing this deficiency could be a valuable addition to current hypothyroid treatments. By recognizing and treating vitamin B12 deficiency, we may improve the overall management of hypothyroid conditions for some patients.
Read More
4
Vitamin B12 linked to hypothyroidism
Vitamin B12 levels in thyroid disorders: A systematic review and meta-analysis.
Focused on hypothyroidism and B12
We explored the relationship between vitamin B12 levels and hypothyroidism by reviewing a range of research studies on this topic. Our analysis included 64 studies, involving nearly 29,000 participants, to understand how vitamin B12 levels differ in those with thyroid disorders compared to healthy individuals.

Our findings indicate that patients with hypothyroidism tend to have lower levels of vitamin B12 compared to those without thyroid issues. Specifically, the data showed a significant mean difference, suggesting that as thyroid dysfunction increases, so may the risk of vitamin B12 deficiency.

However, we did not find any significant differences in vitamin B12 levels when looking at hyperthyroidism or other related thyroid conditions. The prevalence of vitamin B12 deficiency varied among thyroid patients, with 27% of those with hypothyroidism being deficient, compared to lower rates in hyperthyroidism and autoimmune thyroid disease.

While these findings are interesting, it's important to note that the study did not directly assess the effects of vitamin B12 treatment on hypothyroidism. Therefore, we cannot conclude that treating with vitamin B12 leads to significant improvement in hypothyroid conditions.
Read More
4
Hypothyroidism linked to B12 deficiency
Thyroid function and its association with vitamin deficiencies: a case-control study in Duhok.
Association noted, treatment effect unclear
Our research centered on exploring how vitamin B12 levels relate to hypothyroidism, a condition where the thyroid doesn’t produce enough hormones. We analyzed data from a case-control study that included 885 participants, comparing 170 patients with hypothyroidism to 715 healthy individuals.

Through blood tests, we measured various hormone and vitamin levels, including TSH, T3, T4, vitamin D, and vitamin B12. We observed that hypothyroid patients had significantly higher TSH levels and lower T4 levels than the control group. Notably, vitamin B12 levels were also lower in those with hypothyroidism.

Despite these findings suggesting an association between low vitamin B12 and thyroid dysfunction, the study did not specifically test the effects of vitamin B12 treatment on hypothyroidism itself. Therefore, while we can conclude there is a connection, we cannot say for certain that vitamin B12 treatment would improve hypothyroidism. This opens up avenues for future research to further investigate the potential benefits of addressing vitamin B12 deficiencies in managing thyroid conditions.
Read More

Most Useful Reviews

8.8
Enhanced mood
Remarkable for mood and energy, but be cautious of breakouts! I’ve tried numerous supplements and nothing has affected me this positively and quickly. This sublingual B12 has significantly improved my mood swings, energy, and concentration. I’m pleased to have tried it for my anaemia related to hypothyroidism. However, I may need to reduce the dosage due to hairline and back acne reactions caused by high B12 levels.
Read More
8.8
Improved clarity
Great choice! I recommend it to everyone. The perfect balance of price and quality. With hypothyroidism and Hashimoto's thyroiditis, vitamin B12 is essential. After taking it for a month, I felt the improvement from the first day. My hands are no longer cold, and my mind is clearer. I am much less anxious. I take one tablet before bed, sometimes in the morning before a busy day.
Read More

Medical Researches

SCIENTIFIC SCORE
Likely Ineffective
Based on 4 Researches
4.8
7
Vitamin B12 and hypothyroid patients
A Study on Vitamin B12 Levels in Hypothyroid Patients Presenting to a Tertiary Care Teaching Hospital.
Direct relevance to hypothyroid treatment
We explored the connection between vitamin B12 deficiency and hypothyroidism through a focused study involving 100 hypothyroid patients. This research took place over a year and aimed to determine how common vitamin B12 deficiency is among these individuals and how it correlates with thyroid antibodies.

Our findings revealed that a significant 68% of the hypothyroid patients were vitamin B12 deficient. Interestingly, a large majority of these deficient patients were female, specifically 73.5%. Additionally, we noted that a high percentage of patients with elevated Anti TPO and Anti Thyroglobulin antibodies also had low vitamin B12 levels.

Although vitamin B12 deficiency was present in a notable portion of the hypothyroid population, we're careful to point out that the study does not state that vitamin B12 supplementation alone can fully alleviate hypothyroid symptoms. However, it suggests that addressing this deficiency could be a valuable addition to current hypothyroid treatments. By recognizing and treating vitamin B12 deficiency, we may improve the overall management of hypothyroid conditions for some patients.
Read More
4
Hypothyroidism linked to B12 deficiency
Thyroid function and its association with vitamin deficiencies: a case-control study in Duhok.
Association noted, treatment effect unclear
Our research centered on exploring how vitamin B12 levels relate to hypothyroidism, a condition where the thyroid doesn’t produce enough hormones. We analyzed data from a case-control study that included 885 participants, comparing 170 patients with hypothyroidism to 715 healthy individuals.

Through blood tests, we measured various hormone and vitamin levels, including TSH, T3, T4, vitamin D, and vitamin B12. We observed that hypothyroid patients had significantly higher TSH levels and lower T4 levels than the control group. Notably, vitamin B12 levels were also lower in those with hypothyroidism.

Despite these findings suggesting an association between low vitamin B12 and thyroid dysfunction, the study did not specifically test the effects of vitamin B12 treatment on hypothyroidism itself. Therefore, while we can conclude there is a connection, we cannot say for certain that vitamin B12 treatment would improve hypothyroidism. This opens up avenues for future research to further investigate the potential benefits of addressing vitamin B12 deficiencies in managing thyroid conditions.
Read More
4
Vitamin B12 deficiency in hypothyroidism
A Study on Vitamin B12 Levels in Hypothyroid Patients Presenting to a Tertiary Care Teaching Hospital.
Study highlights vitamin B12 links
We conducted a focused study on vitamin B12 levels among patients with hypothyroidism to see how these levels relate to their overall health, particularly in terms of anemia. The analysis involved 100 individuals diagnosed with hypothyroidism, revealing that a significant 68% of them were found to be vitamin B12 deficient.

Among those deficient in vitamin B12, a large majority were women, making up 73.5% of the group. We observed that those with higher levels of anti-thyroid antibodies—specifically anti-TPO and anti-Tg—also tended to experience vitamin B12 deficiency. In fact, 78.6% of patients with raised anti-TPO antibodies were vitamin B12 deficient, indicating a potential relationship between autoimmune responses and vitamin deficiencies in this population.

Despite these insights into the correlation between vitamin B12 levels and thyroid-related antibodies, our findings suggest that vitamin B12 treatment alone does not specifically address hypothyroidism symptoms or provide a significant improvement in their management. Hence, while vitamin B12 deficiency is prevalent among hypothyroid patients, its treatment isn't shown to dramatically influence hypothyroid symptoms directly.
Read More
4
Vitamin B12 linked to hypothyroidism
Vitamin B12 levels in thyroid disorders: A systematic review and meta-analysis.
Focused on hypothyroidism and B12
We explored the relationship between vitamin B12 levels and hypothyroidism by reviewing a range of research studies on this topic. Our analysis included 64 studies, involving nearly 29,000 participants, to understand how vitamin B12 levels differ in those with thyroid disorders compared to healthy individuals.

Our findings indicate that patients with hypothyroidism tend to have lower levels of vitamin B12 compared to those without thyroid issues. Specifically, the data showed a significant mean difference, suggesting that as thyroid dysfunction increases, so may the risk of vitamin B12 deficiency.

However, we did not find any significant differences in vitamin B12 levels when looking at hyperthyroidism or other related thyroid conditions. The prevalence of vitamin B12 deficiency varied among thyroid patients, with 27% of those with hypothyroidism being deficient, compared to lower rates in hyperthyroidism and autoimmune thyroid disease.

While these findings are interesting, it's important to note that the study did not directly assess the effects of vitamin B12 treatment on hypothyroidism. Therefore, we cannot conclude that treating with vitamin B12 leads to significant improvement in hypothyroid conditions.
Read More

User Reviews

USERS' SCORE
Good
Based on 2 Reviews
8.6
8.8
Improved clarity
Great choice! I recommend it to everyone. The perfect balance of price and quality. With hypothyroidism and Hashimoto's thyroiditis, vitamin B12 is essential. After taking it for a month, I felt the improvement from the first day. My hands are no longer cold, and my mind is clearer. I am much less anxious. I take one tablet before bed, sometimes in the morning before a busy day.
Read More
8.8
Enhanced mood
Remarkable for mood and energy, but be cautious of breakouts! I’ve tried numerous supplements and nothing has affected me this positively and quickly. This sublingual B12 has significantly improved my mood swings, energy, and concentration. I’m pleased to have tried it for my anaemia related to hypothyroidism. However, I may need to reduce the dosage due to hairline and back acne reactions caused by high B12 levels.
Read More
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