Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
USERS' SCORE
Good
Based on 2 Reviews
8.5
Supplement Facts
Serving Size:  1 Tablet
Amount Per Serving
%DV
Vitamin B12(as Methylcobalamin)
5,000 mcg
208,330%

Top Medical Research Studies

We aimed to investigate how vitamin B12 can affect the symptoms and overall well-being of fibromyalgia patients. In our study, we worked with individuals diagnosed with fibromyalgia based on established criteria. Participants were given a daily dose of 1000 mcg of oral vitamin B12 to take for fifty days.

Before and after the treatment period, we assessed the patients' conditions using various questionnaires designed to measure pain severity, anxiety, and overall health. Our findings revealed that this short course of vitamin B12 significantly reduced the severity of fibromyalgia symptoms and improved anxiety levels.

Such results suggest that vitamin B12 could play an important role as an adjunctive therapy for managing fibromyalgia. We believe there is potential for further research in this area to enhance treatment options for individuals living with this condition.
Read More
We investigated the connection between vitamin B12 deficiency and the prevalence of fatigue and neurological symptoms in patients with fibromyalgia. By analyzing charts from 2,142 patients diagnosed with fibromyalgia between 2015 and 2020, we set out to see how these symptoms related to B12 levels.

The results were striking: 42.4% of the patients exhibited B12 deficiency, with those lacking sufficient levels reporting higher instances of fatigue and memory loss. Even after considering the impact of vitamin D levels, we found a significant association between B12 deficiency and fatigue, suggesting that addressing this deficiency might help alleviate one of the most burdensome aspects of fibromyalgia.

This study is groundbreaking in highlighting the role of vitamin B12 for patients experiencing fatigue related to fibromyalgia, reinforcing the importance of regular monitoring of vitamin levels in this population. Notably, we found this trend whether we considered the cutoff for B12 deficiency at 400 ng/L or a lower threshold.
Read More
We aimed to understand how vitamin B12 treatment could influence patients with fibromyalgia, particularly those who also have myalgic encephalomyelitis (ME). In this study, we examined clinical data from 38 individuals who received vitamin B12 injections and were also taking oral folic acid.

Patients were categorized into two groups: Good responders, who showed significant improvement, and Mild responders, who had only slight benefits. Those classified as Good responders had higher doses and more frequent B12 injections, as well as greater amounts of folic acid. Interestingly, they did not rely on strong pain medications like opioids, which the Mild responders often used.

Our findings suggest that while vitamin B12 and folic acid can have a positive effect for some, the degree of response varies greatly among individuals. It's also important to note that co-existing thyroid issues might complicate treatment outcomes. The study highlights the potential for vitamin B12 to be part of a comprehensive treatment plan but emphasizes the need for further research to establish effective protocols.
Read More

Most Useful Reviews

9
Vital supplement
8 people found this helpful
Excellent product. It’s an essential supplement for managing my Chronic Fatigue and fibromyalgia. I can't live without it.
Read More
7.5
Increased energy
It genuinely gives me energy! Living with the heaviness of fibromyalgia has been tough. After a few weeks of taking this, I noticed a significant boost in my energy levels. They’re easy to take, with a pleasant flavour. I now manage to accomplish tasks instead of just lying around. I highly recommend this product.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 3 Researches
7.3
  • All Researches
We aimed to investigate how vitamin B12 can affect the symptoms and overall well-being of fibromyalgia patients. In our study, we worked with individuals diagnosed with fibromyalgia based on established criteria. Participants were given a daily dose of 1000 mcg of oral vitamin B12 to take for fifty days.

Before and after the treatment period, we assessed the patients' conditions using various questionnaires designed to measure pain severity, anxiety, and overall health. Our findings revealed that this short course of vitamin B12 significantly reduced the severity of fibromyalgia symptoms and improved anxiety levels.

Such results suggest that vitamin B12 could play an important role as an adjunctive therapy for managing fibromyalgia. We believe there is potential for further research in this area to enhance treatment options for individuals living with this condition.
Read More
We investigated the connection between vitamin B12 deficiency and the prevalence of fatigue and neurological symptoms in patients with fibromyalgia. By analyzing charts from 2,142 patients diagnosed with fibromyalgia between 2015 and 2020, we set out to see how these symptoms related to B12 levels.

The results were striking: 42.4% of the patients exhibited B12 deficiency, with those lacking sufficient levels reporting higher instances of fatigue and memory loss. Even after considering the impact of vitamin D levels, we found a significant association between B12 deficiency and fatigue, suggesting that addressing this deficiency might help alleviate one of the most burdensome aspects of fibromyalgia.

This study is groundbreaking in highlighting the role of vitamin B12 for patients experiencing fatigue related to fibromyalgia, reinforcing the importance of regular monitoring of vitamin levels in this population. Notably, we found this trend whether we considered the cutoff for B12 deficiency at 400 ng/L or a lower threshold.
Read More
We aimed to understand how vitamin B12 treatment could influence patients with fibromyalgia, particularly those who also have myalgic encephalomyelitis (ME). In this study, we examined clinical data from 38 individuals who received vitamin B12 injections and were also taking oral folic acid.

Patients were categorized into two groups: Good responders, who showed significant improvement, and Mild responders, who had only slight benefits. Those classified as Good responders had higher doses and more frequent B12 injections, as well as greater amounts of folic acid. Interestingly, they did not rely on strong pain medications like opioids, which the Mild responders often used.

Our findings suggest that while vitamin B12 and folic acid can have a positive effect for some, the degree of response varies greatly among individuals. It's also important to note that co-existing thyroid issues might complicate treatment outcomes. The study highlights the potential for vitamin B12 to be part of a comprehensive treatment plan but emphasizes the need for further research to establish effective protocols.
Read More

User Reviews

USERS' SCORE
Good
Based on 2 Reviews
8.5
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Vital supplement
8 people found this helpful
Excellent product. It’s an essential supplement for managing my Chronic Fatigue and fibromyalgia. I can't live without it.
Read More
7.5
Increased energy
It genuinely gives me energy! Living with the heaviness of fibromyalgia has been tough. After a few weeks of taking this, I noticed a significant boost in my energy levels. They’re easy to take, with a pleasant flavour. I now manage to accomplish tasks instead of just lying around. I highly recommend this product.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.

References

  1. Gharibpoor F, Ghavidel-Parsa B, Sattari N, Bidari A, Nejatifar F, et al. Effect of vitamin B12 on the symptom severity and psychological profile of fibromyalgia patients; a prospective pre-post study. BMC Rheumatol. 2022;6:51. doi:10.1186/s41927-022-00282-y
  2. Munipalli B, Strothers S, Rivera F, Malavet P, Mitri G, et al. Association of Vitamin B12, Vitamin D, and Thyroid-Stimulating Hormone With Fatigue and Neurologic Symptoms in Patients With Fibromyalgia. Mayo Clin Proc Innov Qual Outcomes. 2022;6:381. doi:10.1016/j.mayocpiqo.2022.06.003
  3. Regland B, Forsmark S, Halaouate L, Matousek M, Peilot B, et al. Response to vitamin B12 and folic acid in myalgic encephalomyelitis and fibromyalgia. PLoS One. 2015;10:e0124648. doi:10.1371/journal.pone.0124648
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