' 
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.9
USERS' SCORE
Good
Based on 1 Review
8.6
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin B12(as Methylcobalamin)
5,000 mcg
208,330%
Top Medical Research Studies
9.5
Vitamin B shows promise for psoriasis
Superiority of a vitamin B-containing emollient compared to a standard emollient in the maintenance treatment of mild-to-moderate plaque psoriasis.
Moderate relevance due to combination use
We conducted a study to examine the effectiveness of a vitamin B-containing ointment in treating mild-to-moderate plaque psoriasis compared to a standard glycerol-petrolatum-based emollient cream. The trial was designed thoughtfully, with 24 patients participating in a randomized, controlled, single-blind format. Each patient received the vitamin B ointment on one side of their body and the standard cream on the other side.
Over the duration of 12 weeks, we periodically measured the severity of psoriasis using the Psoriasis Area Severity Index (PASI). Our findings revealed that the vitamin B ointment significantly reduced the severity of psoriasis compared to the control cream at various times, particularly showing an impressive average reduction of 87.6% from baseline after 12 weeks.
This evidence suggests that vitamin B ointment not only offers a new treatment avenue for psoriasis but also should be considered in future treatment guidelines. We believe our research underscores the potential benefits of a vitamin B therapy approach in managing this chronic skin condition effectively.
Over the duration of 12 weeks, we periodically measured the severity of psoriasis using the Psoriasis Area Severity Index (PASI). Our findings revealed that the vitamin B ointment significantly reduced the severity of psoriasis compared to the control cream at various times, particularly showing an impressive average reduction of 87.6% from baseline after 12 weeks.
This evidence suggests that vitamin B ointment not only offers a new treatment avenue for psoriasis but also should be considered in future treatment guidelines. We believe our research underscores the potential benefits of a vitamin B therapy approach in managing this chronic skin condition effectively.
Read More
8
Recent research highlights the relationship between vitamin B12 and psoriasis, a skin condition linked to various factors including immune response and genetics. We observed that individuals with psoriasis often have elevated levels of homocysteine, which may contribute to the condition. This research pointed to vitamin B12—along with folic acid—as a potential component in managing psoriasis effectively.
Vitamin B12 appears to influence the body's immune processes that are implicated in psoriasis. It may also help tackle the inflammation associated with this skin disease. By alleviating symptoms, topical vitamin B12 treatments might offer some relief for individuals struggling with psoriasis.
Importantly, while systemic treatments using folinate calcium (a folic acid derivative) and topical vitamin B12 have shown effectiveness, it's crucial to consider these in conjunction with other treatments. Overall, vitamin B12 could be seen as a supportive option within a broader strategy to manage psoriasis effectively.
Vitamin B12 appears to influence the body's immune processes that are implicated in psoriasis. It may also help tackle the inflammation associated with this skin disease. By alleviating symptoms, topical vitamin B12 treatments might offer some relief for individuals struggling with psoriasis.
Importantly, while systemic treatments using folinate calcium (a folic acid derivative) and topical vitamin B12 have shown effectiveness, it's crucial to consider these in conjunction with other treatments. Overall, vitamin B12 could be seen as a supportive option within a broader strategy to manage psoriasis effectively.
Read More
7
Vitamin B12 reduces psoriasis risk
Risk of Psoriasis in Postgastrectomy Gastric Cancer Survivors: A Nationwide Population-Based Cohort Study.
Explores vitamin B12’s relevance in psoriasis
We conducted an extensive analysis involving over 50,000 gastric cancer survivors to uncover the link between vitamin B12 treatment and the incidence of psoriasis. This research compared these cancer patients to a matched group from the general population, helping us highlight differences in psoriasis development.
Interestingly, we found that patients who had undergone subtotal gastrectomy exhibited a lower risk of developing psoriasis. Notably, those who supplemented with vitamin B for more than three years experienced additional benefits, suggesting that vitamin B12 could potentially lower psoriasis risk.
However, our findings indicated that other factors, such as total gastrectomy, adjuvant cancer treatments like chemotherapy, and obesity, did not have a significant influence on psoriasis among these survivors. Overall, we observed that the incidence of psoriasis was slightly lower in gastric cancer survivors than in the general public, which could be linked to the reduction of systemic inflammation post-surgery.
Interestingly, we found that patients who had undergone subtotal gastrectomy exhibited a lower risk of developing psoriasis. Notably, those who supplemented with vitamin B for more than three years experienced additional benefits, suggesting that vitamin B12 could potentially lower psoriasis risk.
However, our findings indicated that other factors, such as total gastrectomy, adjuvant cancer treatments like chemotherapy, and obesity, did not have a significant influence on psoriasis among these survivors. Overall, we observed that the incidence of psoriasis was slightly lower in gastric cancer survivors than in the general public, which could be linked to the reduction of systemic inflammation post-surgery.
Read More
Most Useful Reviews
9.5
Improved psoriasis
This is the only type of B-12 I can take due to an MTHFR gene. Since using it, my psoriasis has begun to improve, and my antioxidant levels are finally normal. I had issues absorbing B12 and B6 before, leading to tremors, which have now resolved after two months of use.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 6 Researches
7.9
- All Researches
9.5
Vitamin B shows promise for psoriasis
Superiority of a vitamin B-containing emollient compared to a standard emollient in the maintenance treatment of mild-to-moderate plaque psoriasis.
Moderate relevance due to combination use
We conducted a study to examine the effectiveness of a vitamin B-containing ointment in treating mild-to-moderate plaque psoriasis compared to a standard glycerol-petrolatum-based emollient cream. The trial was designed thoughtfully, with 24 patients participating in a randomized, controlled, single-blind format. Each patient received the vitamin B ointment on one side of their body and the standard cream on the other side.
Over the duration of 12 weeks, we periodically measured the severity of psoriasis using the Psoriasis Area Severity Index (PASI). Our findings revealed that the vitamin B ointment significantly reduced the severity of psoriasis compared to the control cream at various times, particularly showing an impressive average reduction of 87.6% from baseline after 12 weeks.
This evidence suggests that vitamin B ointment not only offers a new treatment avenue for psoriasis but also should be considered in future treatment guidelines. We believe our research underscores the potential benefits of a vitamin B therapy approach in managing this chronic skin condition effectively.
Over the duration of 12 weeks, we periodically measured the severity of psoriasis using the Psoriasis Area Severity Index (PASI). Our findings revealed that the vitamin B ointment significantly reduced the severity of psoriasis compared to the control cream at various times, particularly showing an impressive average reduction of 87.6% from baseline after 12 weeks.
This evidence suggests that vitamin B ointment not only offers a new treatment avenue for psoriasis but also should be considered in future treatment guidelines. We believe our research underscores the potential benefits of a vitamin B therapy approach in managing this chronic skin condition effectively.
Read More
9
Herbal treatment shows promise
A case series of the effects of a novel composition of a traditional natural preparation for the treatment of psoriasis.
Vitamin B12 effects unclear
We assessed the effectiveness of a topical herbal preparation called DurrDerma, designed to treat moderate to severe psoriasis. This preparation combines several natural ingredients, including black cumin, olive oil, tea tree oil, cocoa butter, along with vitamins A and B12. The focus was on seeing how well this combination worked in patients who had severe and treatment-resistant cases of psoriasis.
Our case series involved 12 patients, aged between 21 and 86 years, who used the preparation twice daily for 12 weeks. The results were quite promising. Ten out of the twelve patients (about 83%) achieved significant improvement, with a Psoriasis Area and Severity Index (PASI) score reduction of over 75%. However, two patients only had moderate improvements, with a PASI reduction of 50% or less.
Interestingly, while vitamin B12 was part of the treatment mix, we cannot isolate its specific effects on psoriasis due to its combination with other ingredients. Despite the lack of separate assessment of vitamin B12, the overall findings suggest that the antioxidants and anti-inflammatory properties of DurrDerma may provide a beneficial effect. In summary, our findings indicate that this traditional herbal preparation may serve as a complementary approach to psoriasis management.
Our case series involved 12 patients, aged between 21 and 86 years, who used the preparation twice daily for 12 weeks. The results were quite promising. Ten out of the twelve patients (about 83%) achieved significant improvement, with a Psoriasis Area and Severity Index (PASI) score reduction of over 75%. However, two patients only had moderate improvements, with a PASI reduction of 50% or less.
Interestingly, while vitamin B12 was part of the treatment mix, we cannot isolate its specific effects on psoriasis due to its combination with other ingredients. Despite the lack of separate assessment of vitamin B12, the overall findings suggest that the antioxidants and anti-inflammatory properties of DurrDerma may provide a beneficial effect. In summary, our findings indicate that this traditional herbal preparation may serve as a complementary approach to psoriasis management.
Read More
8
Recent research highlights the relationship between vitamin B12 and psoriasis, a skin condition linked to various factors including immune response and genetics. We observed that individuals with psoriasis often have elevated levels of homocysteine, which may contribute to the condition. This research pointed to vitamin B12—along with folic acid—as a potential component in managing psoriasis effectively.
Vitamin B12 appears to influence the body's immune processes that are implicated in psoriasis. It may also help tackle the inflammation associated with this skin disease. By alleviating symptoms, topical vitamin B12 treatments might offer some relief for individuals struggling with psoriasis.
Importantly, while systemic treatments using folinate calcium (a folic acid derivative) and topical vitamin B12 have shown effectiveness, it's crucial to consider these in conjunction with other treatments. Overall, vitamin B12 could be seen as a supportive option within a broader strategy to manage psoriasis effectively.
Vitamin B12 appears to influence the body's immune processes that are implicated in psoriasis. It may also help tackle the inflammation associated with this skin disease. By alleviating symptoms, topical vitamin B12 treatments might offer some relief for individuals struggling with psoriasis.
Importantly, while systemic treatments using folinate calcium (a folic acid derivative) and topical vitamin B12 have shown effectiveness, it's crucial to consider these in conjunction with other treatments. Overall, vitamin B12 could be seen as a supportive option within a broader strategy to manage psoriasis effectively.
Read More
7
Vitamin B12 reduces psoriasis risk
Risk of Psoriasis in Postgastrectomy Gastric Cancer Survivors: A Nationwide Population-Based Cohort Study.
Explores vitamin B12’s relevance in psoriasis
We conducted an extensive analysis involving over 50,000 gastric cancer survivors to uncover the link between vitamin B12 treatment and the incidence of psoriasis. This research compared these cancer patients to a matched group from the general population, helping us highlight differences in psoriasis development.
Interestingly, we found that patients who had undergone subtotal gastrectomy exhibited a lower risk of developing psoriasis. Notably, those who supplemented with vitamin B for more than three years experienced additional benefits, suggesting that vitamin B12 could potentially lower psoriasis risk.
However, our findings indicated that other factors, such as total gastrectomy, adjuvant cancer treatments like chemotherapy, and obesity, did not have a significant influence on psoriasis among these survivors. Overall, we observed that the incidence of psoriasis was slightly lower in gastric cancer survivors than in the general public, which could be linked to the reduction of systemic inflammation post-surgery.
Interestingly, we found that patients who had undergone subtotal gastrectomy exhibited a lower risk of developing psoriasis. Notably, those who supplemented with vitamin B for more than three years experienced additional benefits, suggesting that vitamin B12 could potentially lower psoriasis risk.
However, our findings indicated that other factors, such as total gastrectomy, adjuvant cancer treatments like chemotherapy, and obesity, did not have a significant influence on psoriasis among these survivors. Overall, we observed that the incidence of psoriasis was slightly lower in gastric cancer survivors than in the general public, which could be linked to the reduction of systemic inflammation post-surgery.
Read More
7
Vitamin B12 and psoriasis treatment
Goeckerman Therapy of Psoriasis: Genotoxicity, Dietary Micronutrients, Homocysteine, and Gene Polymorphisms.
Limited isolated effect noted
We investigated how vitamin B12 levels relate to the effectiveness of Goeckerman therapy (GT) for psoriasis. GT involves the application of coal tar and exposure to ultraviolet radiation, which aims to relieve this chronic skin condition. In our study of 35 patients with severe psoriasis, we observed interesting connections between vitamin B12, homocysteine levels, and genotoxicity.
While we noted that vitamin B12 levels were indeed a point of interest, their isolated impact on psoriasis treatment remains somewhat unclear. We found that higher homocysteine levels correlated with increased DNA damage in patients undergoing GT. Notably, females had lower vitamin B12 levels compared to males and were also more likely to experience higher homocysteine levels—this could indicate a specific nutritional difference worth considering in treatment plans.
Overall, while vitamin B12 was part of our observations, we didn't establish a definitive positive effect of its supplementation on psoriasis management. This prompts further research to comprehensively understand its role in this context.
While we noted that vitamin B12 levels were indeed a point of interest, their isolated impact on psoriasis treatment remains somewhat unclear. We found that higher homocysteine levels correlated with increased DNA damage in patients undergoing GT. Notably, females had lower vitamin B12 levels compared to males and were also more likely to experience higher homocysteine levels—this could indicate a specific nutritional difference worth considering in treatment plans.
Overall, while vitamin B12 was part of our observations, we didn't establish a definitive positive effect of its supplementation on psoriasis management. This prompts further research to comprehensively understand its role in this context.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Review
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Improved psoriasis
This is the only type of B-12 I can take due to an MTHFR gene. Since using it, my psoriasis has begun to improve, and my antioxidant levels are finally normal. I had issues absorbing B12 and B6 before, leading to tremors, which have now resolved after two months of use.
