Last update
5/20/2025

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 15 Reviews
8
Supplement Facts
Serving Size: 1 Softgel
Amount Per Serving
%DV
Phosphatidylserine (PS) from Lecithin (Sunflower) (Helianthus annuus) Seed Oil
100 mg
†

Top Medical Research Studies

8
Phosphatidylserine lowers stress responses
In our study, we looked at how phosphatidylserine supplementation affects mood and stress responses during an anxiety-inducing situation. Participants were divided into four groups, receiving different doses of phosphatidylserine before facing a mental stress test.

We found that the group receiving 400 mg of phosphatidylserine experienced lower stress hormone levels and reported feeling less distressed. However, larger doses did not bring the same benefits, indicating that the 400 mg dosage might be key in alleviating anxiety during stress.

These findings suggest that phosphatidylserine could be a promising option for managing stress-related issues.
Read More

Most Useful Reviews

9
Calms anxiety effectively
10 people found this helpful
Effective immediately, one tablet is great for anxiety feelings before stressful encounters. It alleviates waves of anger and sadness. I tried both capsule and tablet forms and found both work equally well. Although priced high, I’m concerned about low-cost options affecting its effectiveness.
Read More
9
Long-term anxiety solution
1 people found this helpful
I’ve been using this product for years; it’s the best for the price. Taking 2 each night helps manage my anxiety long term, with the option of an extra dose during the day if needed. Highly recommended!
Read More
9
Effective relief
I took PS for anxiety relief and found it to be quite effective.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
  • All Researches
8
Phosphatidylserine lowers stress responses
In our study, we looked at how phosphatidylserine supplementation affects mood and stress responses during an anxiety-inducing situation. Participants were divided into four groups, receiving different doses of phosphatidylserine before facing a mental stress test.

We found that the group receiving 400 mg of phosphatidylserine experienced lower stress hormone levels and reported feeling less distressed. However, larger doses did not bring the same benefits, indicating that the 400 mg dosage might be key in alleviating anxiety during stress.

These findings suggest that phosphatidylserine could be a promising option for managing stress-related issues.
Read More

User Reviews

USERS' SCORE
Good
Based on 15 Reviews
8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Calms anxiety effectively
10 people found this helpful
Effective immediately, one tablet is great for anxiety feelings before stressful encounters. It alleviates waves of anger and sadness. I tried both capsule and tablet forms and found both work equally well. Although priced high, I’m concerned about low-cost options affecting its effectiveness.
Read More
9
Long-term anxiety solution
1 people found this helpful
I’ve been using this product for years; it’s the best for the price. Taking 2 each night helps manage my anxiety long term, with the option of an extra dose during the day if needed. Highly recommended!
Read More
9
Effective relief
I took PS for anxiety relief and found it to be quite effective.
Read More
9
Boosts focus and calm
I purchased it for my husband to help maintain memory and attention. It works well for the brain overall, and it also reduces anxiety and stress. I recommend it.
Read More
7.5
Very helpful
We love this product. It helps with anxiety.
Read More

Frequently Asked Questions

9
Calms anxiety effectively
10 people found this helpful
Effective immediately, one tablet is great for anxiety feelings before stressful encounters. It alleviates waves of anger and sadness. I tried both capsule and tablet forms and found both work equally well. Although priced high, I’m concerned about low-cost options affecting its effectiveness.
7.5
Reduces stress response
This helps with my anxiety. I take Jarrow's PS100 2 to 3 times daily, as recommended by an integrative doctor. It seems to take the edge off my stress response, which is beneficial overall for anxiety.
7.5
Baseline reduction
It helps to reduce baseline anxiety when used consistently.
7.5
Essential anxiety aid
3 people found this helpful
This product is non-negotiable for me. Jarrow is a trusted brand, and I appreciate the easy-to-swallow softgels. P-Serine helps stabilise my mood, reducing anxiety and nightmares. In times of heightened anxiety, I increase my dosage for further calming effects.
2
Ineffective for anxiety
Pretty good! My doctor recommended it for anxiety, but it didn't seem to help me. However, I gave it to my mum as a sleeping aid and she said she has never slept better!
8
Phosphatidylserine lowers stress responses
In our study, we looked at how phosphatidylserine supplementation affects mood and stress responses during an anxiety-inducing situation. Participants were divided into four groups, receiving different doses of phosphatidylserine before facing a mental stress test.

We found that the group receiving 400 mg of phosphatidylserine experienced lower stress hormone levels and reported feeling less distressed. However, larger doses did not bring the same benefits, indicating that the 400 mg dosage might be key in alleviating anxiety during stress.

These findings suggest that phosphatidylserine could be a promising option for managing stress-related issues.

References

  1. Hellhammer J, Fries E, Buss C, Engert V, Tuch A, et al. Effects of soy lecithin phosphatidic acid and phosphatidylserine complex (PAS) on the endocrine and psychological responses to mental stress. Stress. 2004;7:119.
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