We examined how quercetin, a popular plant-based antioxidant, affects skin inflammation caused by the acne-causing bacteria Propionibacterium acnes. Through both laboratory and mouse studies, we found that quercetin significantly decreased inflammation-related proteins and cell responses triggered by this bacteria. When tested on mice, quercetin reduced swelling and redness at the injection site. These findings suggest that quercetin could serve as a beneficial treatment option for acne-related inflammation, opening doors for its use in skin care products and therapies.
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We explored how quercetin, a natural compound, can be effectively delivered for acne treatment using innovative vitamin C-based nanovesicles called aspasomes.
The study analyzed their ability to penetrate the skin and combat acne-causing bacteria, revealing significant antibacterial properties.
In a clinical trial involving 20 acne patients, we observed substantial reductions in inflammatory lesions and total acne lesions.
These results suggest that quercetin-loaded aspasomes could be a promising option for acne therapy, highlighting the potential of combining nutraceuticals with advanced delivery systems.
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Quercetin patch shows promise for acneSolution blow spun bilayer chitosan/polylactic acid nanofibrous patch with antibacterial and anti-inflammatory properties for accelerating acne healing.
High relevance for acne treatment
We designed a unique nanofibrous patch that combines quercetin with chitosan and polylactic acid to tackle acne. This innovative patch effectively releases quercetin over 24 hours and shows remarkable antibacterial properties against acne-causing bacteria.
Additionally, it significantly reduces inflammation, contributing to healing. With a high free radical clearance rate and excellent compatibility, this patch could become a promising solution for treating acne wounds caused by bacterial infections.
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BHHD effectively improves PCOS symptomsIntegrated Network Pharmacology and Clinical Study to Reveal the Effects and Mechanisms of Bushen Huoxue Huatan Decoction on Polycystic Ovary Syndrome.
High relevance in PCOS treatment
We explored the efficacy of Bushen Huoxue Huatan Decoction (BHHD) for treating polycystic ovary syndrome (PCOS) by combining network pharmacology with a clinical trial involving 62 patients.
After three months of treatment, many participants saw improvements in ovulation rates and symptoms like acne.
The study suggested that BHHD works by balancing hormone levels, improving insulin sensitivity, reducing inflammation, and enhancing fertility. Overall, BHHD appears to be a promising option for those struggling with PCOS and its associated symptoms.
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Quercetin nanofibers reduce acneQuercetin loaded cosm-nutraceutical electrospun composite nanofibers for acne alleviation: Preparation, characterization and experimental clinical appraisal.
Highly relevant acne treatment study
We explored a new approach to acne treatment through composite nanofibers that deliver quercetin, known for its soothing and antibacterial properties. In our study, these nanofibers were tested for their efficiency in reducing acne, and the results were promising.
Patients experienced a remarkable 61.2% reduction in inflammatory lesions and a 52.9% decrease in total acne lesions. Our findings suggest that this innovative nanofiber delivery system could be a game-changer in treating acne effectively.
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