Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.1
USERS' SCORE
Good
Based on 134 Reviews
8.3
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Saccharomyces boulardii(an S. cerevisiae Strain)
250 mg(5 Billion CFU)
MOS Yeast Fraction(Min. 35% Manno-oligosaccharides [MOS]) (S. cerevisiae)
200 mg

Top Medical Research Studies

We analyzed data from two clinical trials involving 579 individuals with Irritable Bowel Syndrome (IBS) to determine how CNCM I-3856 affects symptoms like bloating.

Our findings revealed that during the second month of supplementation, participants experienced significant reductions in both abdominal pain and bloating—up to 14.9% compared to those taking a placebo.

While intestinal symptoms improved, there were no significant differences observed between groups at the end of treatment. However, stool consistency was notably better in those taking CNCM I-3856.
Read More
We looked into how probiotics, like Saccharomyces boulardii, can help prevent antibiotic-associated diarrhea (AAD) in children. Involving 23 studies with nearly 4,000 participants, our findings indicate a significant benefit from probiotics, with AAD occurring in 8% of the probiotic group versus 19% in the control group.

It appears that probiotics, particularly certain strains, can help keep children's gut health intact during antibiotic treatments. While no serious side effects were recorded, some mild issues like bloating were noted. Overall, moderate evidence supports using these probiotics to ward off AAD.
Read More
8
Probiotic treatment resolved infection
We examined a case involving a 41-year-old man who suffered from cramps, bloating, and watery diarrhea after drinking non-potable water. While initial tests ruled out gluten intolerance and other infectious agents, a deeper analysis eventually identified the presence of Blastocystis hominis. This protozoan is known to be associated with chronic intestinal issues and can be waterborne. Remarkably, treatment with the probiotic Saccharomyces boulardii seemed to effectively resolve the infection. This suggests that Saccharomyces boulardii might offer a beneficial approach for managing similar cases.
Read More

Most Useful Reviews

9.5
Bloating relief
Saccharomyces Boulardii was highly recommended to me, and it definitely works. After two weeks, I noticed significant improvements—my bloating after meals ceased, and the discomfort and gases disappeared. I take two capsules before bed, and I feel much better overall. This product is essential for anyone dealing with gastrointestinal issues. Highly recommend!
Read More
8.8
Constipation relief
This supplement is fantastic; it alleviates constipation and stops bloating effectively. My gut feels much better since taking it.
Read More
8.8
Bloating reduction
These probiotics are remarkable. They help restore intestinal microflora, reduce bloating, and improve my skin condition. I'm pleased with the results so far.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 15 Researches
7.1
  • All Researches
We looked into how probiotics, like Saccharomyces boulardii, can help prevent antibiotic-associated diarrhea (AAD) in children. Involving 23 studies with nearly 4,000 participants, our findings indicate a significant benefit from probiotics, with AAD occurring in 8% of the probiotic group versus 19% in the control group.

It appears that probiotics, particularly certain strains, can help keep children's gut health intact during antibiotic treatments. While no serious side effects were recorded, some mild issues like bloating were noted. Overall, moderate evidence supports using these probiotics to ward off AAD.
Read More
8
Probiotics significantly reduce bloating
We explored the effectiveness of the probiotic supplement Saccharomyces boulardii in reducing bloating and gastric pain among airline pilots suffering from chronic non-atrophic gastritis.

Over four weeks, participants were divided into groups receiving different doses of the probiotic or undergoing watchful waiting.

The results showed that both probiotic doses significantly improved symptoms compared to the control group, but only the high-dose led to notable changes in certain serum markers.

Overall, this suggests that Saccharomyces boulardii could help ease bloating and gastric discomfort in situations where these issues are common.
Read More
In this clinical trial, we evaluated the impact of Saccharomyces boulardii on patients with small intestinal bacterial overgrowth (SIBO) related to systemic sclerosis (SSc).

We examined the effects of S. boulardii alone, with metronidazole, or in combination for two months.

Results showed that both S. boulardii and the combination treatment significantly reduced gastrointestinal symptoms, including bloating, while metronidazole alone had limited success.

Overall, S. boulardii proves beneficial, giving hope to those suffering from related discomfort.
Read More
8
Probiotic treatment resolved infection
We examined a case involving a 41-year-old man who suffered from cramps, bloating, and watery diarrhea after drinking non-potable water. While initial tests ruled out gluten intolerance and other infectious agents, a deeper analysis eventually identified the presence of Blastocystis hominis. This protozoan is known to be associated with chronic intestinal issues and can be waterborne. Remarkably, treatment with the probiotic Saccharomyces boulardii seemed to effectively resolve the infection. This suggests that Saccharomyces boulardii might offer a beneficial approach for managing similar cases.
Read More
8
Probiotics reduce pediatric AAD risk
We explored how probiotics might help prevent antibiotic-associated diarrhea (AAD) in children. By analyzing 23 studies involving almost 4,000 young participants, we found that probiotics significantly reduced AAD incidence compared to placebo or no treatment.

Specifically, AAD occurred in 8% of children receiving probiotics versus 19% in the control groups. We noted that Lactobacillus rhamnosus and Saccharomyces boulardii were among the most effective strains.

While adverse events were mild and rare, further research is needed regarding other probiotic strains, especially for at-risk children.
Read More

User Reviews

USERS' SCORE
Good
Based on 134 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Bloating relief
Saccharomyces Boulardii was highly recommended to me, and it definitely works. After two weeks, I noticed significant improvements—my bloating after meals ceased, and the discomfort and gases disappeared. I take two capsules before bed, and I feel much better overall. This product is essential for anyone dealing with gastrointestinal issues. Highly recommend!
Read More
8.8
Constipation relief
This supplement is fantastic; it alleviates constipation and stops bloating effectively. My gut feels much better since taking it.
Read More
8.8
Bloating reduction
These probiotics are remarkable. They help restore intestinal microflora, reduce bloating, and improve my skin condition. I'm pleased with the results so far.
Read More
8.8
Bloating improvement
Suffering from ulcerative colitis, I began using this product on my doctor's advice. After a few weeks, I experienced regular bowel movements, less cramping, and significantly reduced bloating. Overall, I feel better and even noticed smoother skin.
Read More
9.5
Digestion support
After suffering from rotavirus, I started taking Boulardi sugaryomycetes, and they dramatically improved my digestion and bowel function within days. They are also invaluable when taking antibiotics and for maintaining intestinal health.
Read More

Frequently Asked Questions

Bloating is a common gastrointestinal condition characterized by a sensation of fullness, tightness, or swelling in the abdomen. It often occurs after eating and can be accompanied by visible distension of the belly. This discomfort may be caused by various factors, including excessive gas production, food intolerances, overeating, or certain medical conditions affecting the digestive system. Many people experience bloating occasionally, but when it becomes chronic, it can significantly impact one's quality of life.

Managing bloating typically involves dietary adjustments, such as identifying and avoiding trigger foods, eating smaller meals, and incorporating more fiber into your diet. Staying hydrated and engaging in regular physical activity can also help alleviate symptoms. If bloating is persistent or accompanied by other troubling symptoms like severe pain or changes in bowel habits, it is advisable to consult a healthcare professional for proper evaluation and guidance.

Saccharomyces boulardii is a beneficial yeast strain known for its probiotic properties. Originally isolated from lychee and mangosteen fruit in the 1920s by French microbiologist Henri Boulard, this yeast is widely recognized for its ability to support digestive health. It is commonly used to prevent and treat diarrhea, especially in cases related to antibiotic use or gastrointestinal infections. Saccharomyces boulardii works by helping to maintain the natural balance of good bacteria in the gut, promoting the growth of beneficial microorganisms, and producing substances that inhibit pathogen growth.

In addition to its anti-diarrheal benefits, research suggests that Saccharomyces boulardii may also contribute to other health benefits, including digestive recovery after gastrointestinal illness and potential support for conditions like irritable bowel syndrome (IBS). While it is generally regarded as safe for most individuals, those with compromised immune systems or central venous catheters should consult healthcare professionals prior to use. As always, it's best to choose high-quality supplements that clearly specify the strain and dosage of Saccharomyces boulardii to ensure efficacy.

Saccharomyces boulardii, a probiotic yeast, has shown promise in supporting digestive health, and some research suggests it may help alleviate bloating and other gastrointestinal discomforts. This specific strain can balance gut flora and potentially reduce the effects of certain gastrointestinal disorders, such as diarrhea and irritable bowel syndrome (IBS), which are often accompanied by bloating.

While scientific evidence supports probiotics' general benefits for digestive health, response can vary from person to person. If you're considering Saccharomyces boulardii for bloating, it's advisable to consult with a healthcare professional to determine whether it's suitable for your situation and how it might fit into your overall health plan. Remember, maintaining a balanced gut microbiome is essential for optimal digestive function, and adding probiotics like Saccharomyces boulardii could be a beneficial component.

Based on user reviews, many individuals report experiencing relief from bloating within a relatively short period after starting this supplement. For instance, one user noticed significant improvements after just two weeks of use, stating that their bloating after meals had ceased completely (Read Review). Similar experiences are echoed by others, with some users reporting improvements in just days (Read Review).

However, results can vary from person to person. Some individuals found the product effective after a few weeks (Read Review) while others didn't notice immediate effects and required more time to see benefits (Read Review). Overall, while many users reported quick relief, it seems that consistency in use is key to achieving optimal results in alleviating bloating.

Recent scientific research points towards the effectiveness of specific probiotic supplements, particularly Saccharomyces boulardii, in alleviating bloating. A systematic review and clinical evaluations showed that this probiotic can significantly reduce gastrointestinal symptoms, including bloating in various populations, such as individuals with chronic gastritis and small intestinal bacterial overgrowth (SIBO) [2] [3]. Moreover, studies indicated that when combined with traditional treatments for H. pylori, Saccharomyces boulardii led to fewer side effects, including reduced bloating, although it did not significantly enhance the rate of infection eradication [8].

In addition to Saccharomyces boulardii, the role of EpiCor and other yeast-based supplements in managing gastrointestinal discomfort is also explored; however, findings show that while EpiCor can improve gut microbiome composition and help with constipation, there is no straightforward evidence supporting its effectiveness against bloating [10]. Overall, the consensus from the research suggests that probiotics, particularly Saccharomyces boulardii, hold promise as a supportive approach to reducing bloating, highlighting the importance of individual responses to such supplements.

Based on user reviews, many individuals report significant improvements in gastrointestinal symptoms after taking Saccharomyces Boulardii. For instance, several users have highlighted reductions in bloating, with one individual mentioning that their bloating after meals completely ceased within two weeks of use (Read Review). Another user affirmed experiencing enhanced digestion and bowel function within just days of starting the supplement (Read Review). Many have also cited improvements in related symptoms like constipation, abdominal cramps, and even skin conditions attributed to better intestinal health (Read Review).

However, it is essential to note that individual results can vary. While numerous users reported quick and effective relief from bloating and other gastrointestinal issues, some individuals did not see the desired effects, experiencing worsened symptoms instead (Read Review). Yet, a prevailing sentiment among many users showcases that consistent use is crucial for achieving optimal results in alleviating symptoms (Read Review). As with any supplement, personal experiences will differ, and it's advisable to consult with a healthcare professional for tailored advice.

Users report various experiences when combining Saccharomyces Boulardii with other supplements for managing bloating. Many individuals highlight the effectiveness of pairing this probiotic with fiber, as it seems to enhance its benefits significantly. One user noted that this combination resulted in reduced bloating, burping, and improved overall digestive health (Read Review). Additionally, several reviewers mentioned that taking the supplement during or after antibiotic courses proved particularly helpful in alleviating bloating and maintaining gut health (Read Review).

However, it's worth mentioning that not all experiences were positive. Some users indicated that they did not see the expected improvements when combining it with certain other supplements or when dealing with specific gastrointestinal conditions (Read Review). Therefore, while many users enjoyed the synergistic benefits of pairing Saccharomyces Boulardii with additional fibers or other supportive supplements, individual responses can vary significantly, suggesting the importance of personal experimentation and possibly consulting with a healthcare professional for tailored advice.

When it comes to alleviating bloating, research points to the probiotic Saccharomyces boulardii as a promising option, particularly at higher doses. One study examining the effects of S. boulardii in airline pilots with chronic gastric issues found that participants receiving the higher dosage of the probiotic experienced notable improvements in their bloating symptoms compared to those on a lower dose or no treatment at all [2]. Additionally, when evaluating its impact on patients with small intestinal bacterial overgrowth (SIBO), researchers found that S. boulardii significantly alleviated gastrointestinal discomfort, including bloating, further indicating its effectiveness [3].

Moreover, in a trial involving patients undergoing treatment for H. pylori infections, S. boulardii was shown to not only reduce incidences of bloating but also helped manage other gastrointestinal side effects commonly associated with antibiotic treatments [8]. While specific dosage recommendations may vary, studies suggest that patients seeking relief from bloating should consider higher doses of Saccharomyces boulardii to achieve better results. For those integrating this probiotic into their health regimen, consulting a healthcare professional for personalized dosage guidance is recommended to ensure optimal outcomes.

9.5
Bloating relief
Saccharomyces Boulardii was highly recommended to me, and it definitely works. After two weeks, I noticed significant improvements—my bloating after meals ceased, and the discomfort and gases disappeared. I take two capsules before bed, and I feel much better overall. This product is essential for anyone dealing with gastrointestinal issues. Highly recommend!
9.5
Digestion support
After suffering from rotavirus, I started taking Boulardi sugaryomycetes, and they dramatically improved my digestion and bowel function within days. They are also invaluable when taking antibiotics and for maintaining intestinal health.
8.8
Bloating improvement
Suffering from ulcerative colitis, I began using this product on my doctor's advice. After a few weeks, I experienced regular bowel movements, less cramping, and significantly reduced bloating. Overall, I feel better and even noticed smoother skin.
9.5
No bloating
Excellent! I didn’t notice much difference initially; however, I appreciate its benefits. As a yeast probiotic, it survives antibiotics and my stomach felt fine without any bloating whilst using it.
8.8
Bloating reduction
These probiotics are remarkable. They help restore intestinal microflora, reduce bloating, and improve my skin condition. I'm pleased with the results so far.
3.5
Worsened bloating
I have leaky gut and took this Bacillus subtilis to help, but it made my bloating worse. I should have been more cautious with my choice.
9.5
Less bloating
Fantastic probiotic yeast! Best paired with fibre. This works much better for me than regular CFU probiotics, which did nothing even after months. I noticed effects within a couple of days with two pills a day: reduced bloating, burping, improved stools, and significantly less stomach cramping and pain! Can't recommend enough for IBS sufferers and those with gut issues.
8
Probiotics significantly reduce bloating
We explored the effectiveness of the probiotic supplement Saccharomyces boulardii in reducing bloating and gastric pain among airline pilots suffering from chronic non-atrophic gastritis.

Over four weeks, participants were divided into groups receiving different doses of the probiotic or undergoing watchful waiting.

The results showed that both probiotic doses significantly improved symptoms compared to the control group, but only the high-dose led to notable changes in certain serum markers.

Overall, this suggests that Saccharomyces boulardii could help ease bloating and gastric discomfort in situations where these issues are common.
In this clinical trial, we evaluated the impact of Saccharomyces boulardii on patients with small intestinal bacterial overgrowth (SIBO) related to systemic sclerosis (SSc).

We examined the effects of S. boulardii alone, with metronidazole, or in combination for two months.

Results showed that both S. boulardii and the combination treatment significantly reduced gastrointestinal symptoms, including bloating, while metronidazole alone had limited success.

Overall, S. boulardii proves beneficial, giving hope to those suffering from related discomfort.
7
Saccharomyces boulardii reduces bloating effects
We evaluated the effects of the probiotic Saccharomyces boulardii on bloating in patients undergoing treatment for H. pylori infection. In a randomized controlled trial, 160 adults were divided into two groups: one received standard antibiotics along with Saccharomyces boulardii, while the other was treated with antibiotics alone.

Although the addition of the probiotic resulted in significantly fewer side effects, including bloating, it did not lead to a notable improvement in eradicating H. pylori. This suggests that while Saccharomyces boulardii may help with discomfort, it doesn't enhance the overall success of H. pylori treatment.
7
Yeast treatment shows mixed results
We investigated the effects of EpiCor fermentate on gastrointestinal discomfort and constipation, focusing on bloating. In a randomized double-blind trial, eighty participants tracked their symptoms over six weeks, comparing a yeast-based treatment to a placebo. While the results showed that EpiCor could positively influence gut microbiome composition and improve constipation symptoms, there was no significant direct benefit reported for bloating relief. So, while EpiCor can help with certain bowel issues, its effectiveness may not extend to all gastrointestinal discomforts.

References

  1. Li M, Xie Y. Efficacy and safety of as an adjuvant therapy for the eradication of : a meta-analysis. Front Cell Infect Microbiol. 2025;15:1441185. doi:10.3389/fcimb.2025.1441185
  2. Minoretti P, Liaño Riera M, Santiago Sáez A, Gómez Serrano M, García Martín Á. Probiotic Supplementation With Saccharomyces boulardii and Enterococcus faecium Improves Gastric Pain and Bloating in Airline Pilots With Chronic Non-atrophic Gastritis: An Open-Label Study. Cureus. 2024;16:e52502. doi:10.7759/cureus.52502
  3. García-Collinot G, Madrigal-Santillán EO, Martínez-Bencomo MA, Carranza-Muleiro RA, Jara LJ, et al. Effectiveness of Saccharomyces boulardii and Metronidazole for Small Intestinal Bacterial Overgrowth in Systemic Sclerosis. Dig Dis Sci. 2020;65:1134. doi:10.1007/s10620-019-05830-0
  4. Angelici MC, Nardis C, Scarpelli R, Ade P. Blastocystis hominis transmission by non-potable water: a case report in Italy. New Microbiol. 2018;41:173.
  5. Feng JR, Wang F, Qiu X, McFarland LV, Chen PF, et al. Efficacy and safety of probiotic-supplemented triple therapy for eradication of Helicobacter pylori in children: a systematic review and network meta-analysis. Eur J Clin Pharmacol. 2017;73:1199. doi:10.1007/s00228-017-2291-6
  6. Hayes SR, Vargas AJ. Probiotics for the Prevention of Pediatric Antibiotic-Associated Diarrhea. Explore (NY). 2016;12:463. doi:10.1016/j.explore.2016.08.015
  7. Goldenberg JZ, Lytvyn L, Steurich J, Parkin P, Mahant S, et al. Probiotics for the prevention of pediatric antibiotic-associated diarrhea. Cochrane Database Syst Rev. 2015. doi:10.1002/14651858.CD004827.pub4
  8. Zojaji H, Ghobakhlou M, Rajabalinia H, Ataei E, Jahani Sherafat S, et al. The efficacy and safety of adding the probiotic Saccharomyces boulardiito standard triple therapy for eradication of H.pylori: a randomized controlled trial. Gastroenterol Hepatol Bed Bench. 2013;6:S99.
  9. Polese B, Nicolai E, Genovese D, Verlezza V, La Sala CN, et al. Postprandial Gastrointestinal Function Differs after Acute Administration of Sourdough Compared with Brewer's Yeast Bakery Products in Healthy Adults. J Nutr. 2018;148:202. doi:10.1093/jn/nxx049
  10. Pinheiro I, Robinson L, Verhelst A, Marzorati M, Winkens B, et al. A yeast fermentate improves gastrointestinal discomfort and constipation by modulation of the gut microbiome: results from a randomized double-blind placebo-controlled pilot trial. BMC Complement Altern Med. 2017;17:441. doi:10.1186/s12906-017-1948-0
  11. Cayzeele-Decherf A, Pélerin F, Leuillet S, Douillard B, Housez B, et al. CNCM I-3856 in irritable bowel syndrome: An individual subject meta-analysis. World J Gastroenterol. 2017;23:336. doi:10.3748/wjg.v23.i2.336
  12. Spiller R, Pélerin F, Cayzeele Decherf A, Maudet C, Housez B, et al. Randomized double blind placebo-controlled trial of Saccharomyces cerevisiae CNCM I-3856 in irritable bowel syndrome: improvement in abdominal pain and bloating in those with predominant constipation. United European Gastroenterol J. 2016;4:353. doi:10.1177/2050640615602571
  13. Pineton de Chambrun G, Neut C, Chau A, Cazaubiel M, Pelerin F, et al. A randomized clinical trial of Saccharomyces cerevisiae versus placebo in the irritable bowel syndrome. Dig Liver Dis. 2015;47:119. doi:10.1016/j.dld.2014.11.007
  14. Moya D, Calsamiglia S, Ferret A, Blanch M, Fandiño JI, et al. Effects of dietary changes and yeast culture (Saccharomyces cerevisiae) on rumen microbial fermentation of Holstein heifers. J Anim Sci. 2009;87:2874. doi:10.2527/jas.2008-1446
  15. Treem WR, McAdams L, Stanford L, Kastoff G, Justinich C, et al. Sacrosidase therapy for congenital sucrase-isomaltase deficiency. J Pediatr Gastroenterol Nutr. 1999;28:137.
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