Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.4
USERS' SCORE
Good
Based on 3 Reviews
8.2
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Saccharomyces boulardii(an S. cerevisiae Strain)
250 mg(5 Billion CFU)
MOS Yeast Fraction(Min. 35% Manno-oligosaccharides [MOS]) (S. cerevisiae)
200 mg

Top Medical Research Studies

7
Cardiovascular benefits of yeast compound
We explored how carboxymethyl-glucan, a compound from yeast, impacts heart health in hypertensive rats. Rats were divided into groups, with some receiving carboxymethyl-glucan for four weeks while others received a placebo.

Results showed that carboxymethyl-glucan improved vascular function and decreased platelet aggregation, especially at a high dose. However, it didn’t lower levels of harmful molecules called reactive oxygen species, indicating it may not fully protect against all cardiovascular issues.

Overall, this compound shows promise in helping to manage hypertension and related complications.
Read More
9
Probiotic lowers cholesterol in hamsters
We explored the effects of the CNCM I-745 probiotic on cholesterol levels and gut bacteria in hamsters with high cholesterol. This controlled study revealed that daily doses significantly lowered total plasma cholesterol and altered gut microbiota. Specifically, we noted that the abundance of certain gut microbes was linked to changes in cholesterol levels and liver gene expression. These findings suggest that this probiotic not only benefits cholesterol levels but also supports gut health, offering potential for safe treatments in managing hypercholesterolemia.
Read More
8
S. boulardii reduces lung injury
We explored the effects of the probiotic Saccharomyces boulardii on lung injury caused by aortic ischemia-reperfusion in rats. Twenty-one rats were divided into three groups, one receiving the probiotic and others receiving saline.

After the aorta was clamped, we noticed that those treated with S. boulardii experienced significantly less lung damage and reduced oxidative stress. This suggests the probiotic helps lower inflammation and oxidative stress markers, potentially leading to better outcomes in cardiovascular procedures.
Read More

Most Useful Reviews

9
Remission for Crohn's
1 people found this helpful
I really like this probiotic and would give it ten stars if possible. My husband has severe Crohn's Disease, and his doctor said hospice was the next step. This product has put his disease into remission, and he is significantly better with this formula. It's truly amazing!
Read More
8
Supports cardiovascular health
9 people found this helpful
Awesome product! My cardiologist and primary care physicians both recommended probiotics for my health maintenance. At 83 and my husband at 87, we were advised that you can never have too many probiotics. This product includes both prebiotics and probiotics, which we feel our bodies absorb easily, contributing to our gut well-being and easing discomfort. Finest ingredients.
Read More
4
Prevents cardiovascular disease
1 people found this helpful
Indispensable for treatment and prevention. Medicine acknowledges the beneficial properties of saccharomycetes for diabetes and obesity, as it swiftly alters intestinal microbiota, reducing body fat and improving liver steatosis. Prophylactic use of S. Boulardii lowers the risk of cardiovascular disease while effectively treating constipation, diarrhoea, giardiasis, and fungal infections.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.4
  • All Researches
9
Probiotic lowers cholesterol in hamsters
We explored the effects of the CNCM I-745 probiotic on cholesterol levels and gut bacteria in hamsters with high cholesterol. This controlled study revealed that daily doses significantly lowered total plasma cholesterol and altered gut microbiota. Specifically, we noted that the abundance of certain gut microbes was linked to changes in cholesterol levels and liver gene expression. These findings suggest that this probiotic not only benefits cholesterol levels but also supports gut health, offering potential for safe treatments in managing hypercholesterolemia.
Read More
8
S. boulardii reduces lung injury
We explored the effects of the probiotic Saccharomyces boulardii on lung injury caused by aortic ischemia-reperfusion in rats. Twenty-one rats were divided into three groups, one receiving the probiotic and others receiving saline.

After the aorta was clamped, we noticed that those treated with S. boulardii experienced significantly less lung damage and reduced oxidative stress. This suggests the probiotic helps lower inflammation and oxidative stress markers, potentially leading to better outcomes in cardiovascular procedures.
Read More
7
We explored the role of selenium and zinc enriched postbiotic yeast in addressing gut dysbiosis linked to cardiovascular disease. This study involved analyzing the effects of these postbiotics on microbial populations in the digestive system using various scientific methods.

We found that treatment with the enriched postbiotics led to a notable increase in beneficial bacteria and acetic acid levels. These results suggest that selenium and zinc postbiotics may hold therapeutic potential as adjuncts in treating cardiovascular diseases by improving gut health.
Read More
7
Probiotic yeast improves heart-healthy fats
This innovative study evaluated how adding the probiotic yeast Saccharomyces boulardii to buckwheat sprouts affects their fatty acid composition. Through careful analysis, we found that this modification leads to noteworthy changes in fatty acids, including palmitic and oleic acids.

These changes may enhance the nutritional value of buckwheat sprouts, potentially contributing to a reduced risk of cardiovascular disease. Overall, our findings suggest that probiotic-rich buckwheat sprouts could serve as a functional dietary option for heart health.
Read More
7
Reduced remnant lipoprotein observed
We investigated how the probiotic yeast Saccharomyces boulardii affects blood cholesterol levels in adults with high cholesterol. In this single-arm, open-label pilot study, twelve participants took a specified dose of S. boulardii for eight weeks. While we monitored various cholesterol levels and cardiovascular health markers, results showed a noteworthy reduction in remnant lipoprotein, which could play a role in preventing coronary artery disease. However, overall cholesterol levels did not significantly change during the study.
Read More

User Reviews

USERS' SCORE
Good
Based on 3 Reviews
8.2
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Remission for Crohn's
1 people found this helpful
I really like this probiotic and would give it ten stars if possible. My husband has severe Crohn's Disease, and his doctor said hospice was the next step. This product has put his disease into remission, and he is significantly better with this formula. It's truly amazing!
Read More
8
Supports cardiovascular health
9 people found this helpful
Awesome product! My cardiologist and primary care physicians both recommended probiotics for my health maintenance. At 83 and my husband at 87, we were advised that you can never have too many probiotics. This product includes both prebiotics and probiotics, which we feel our bodies absorb easily, contributing to our gut well-being and easing discomfort. Finest ingredients.
Read More
4
Prevents cardiovascular disease
1 people found this helpful
Indispensable for treatment and prevention. Medicine acknowledges the beneficial properties of saccharomycetes for diabetes and obesity, as it swiftly alters intestinal microbiota, reducing body fat and improving liver steatosis. Prophylactic use of S. Boulardii lowers the risk of cardiovascular disease while effectively treating constipation, diarrhoea, giardiasis, and fungal infections.
Read More

Frequently Asked Questions

9
Remission for Crohn's
1 people found this helpful
I really like this probiotic and would give it ten stars if possible. My husband has severe Crohn's Disease, and his doctor said hospice was the next step. This product has put his disease into remission, and he is significantly better with this formula. It's truly amazing!
8
Supports cardiovascular health
9 people found this helpful
Awesome product! My cardiologist and primary care physicians both recommended probiotics for my health maintenance. At 83 and my husband at 87, we were advised that you can never have too many probiotics. This product includes both prebiotics and probiotics, which we feel our bodies absorb easily, contributing to our gut well-being and easing discomfort. Finest ingredients.
4
Prevents cardiovascular disease
1 people found this helpful
Indispensable for treatment and prevention. Medicine acknowledges the beneficial properties of saccharomycetes for diabetes and obesity, as it swiftly alters intestinal microbiota, reducing body fat and improving liver steatosis. Prophylactic use of S. Boulardii lowers the risk of cardiovascular disease while effectively treating constipation, diarrhoea, giardiasis, and fungal infections.
7
We explored the role of selenium and zinc enriched postbiotic yeast in addressing gut dysbiosis linked to cardiovascular disease. This study involved analyzing the effects of these postbiotics on microbial populations in the digestive system using various scientific methods.

We found that treatment with the enriched postbiotics led to a notable increase in beneficial bacteria and acetic acid levels. These results suggest that selenium and zinc postbiotics may hold therapeutic potential as adjuncts in treating cardiovascular diseases by improving gut health.
8
S. boulardii reduces lung injury
We explored the effects of the probiotic Saccharomyces boulardii on lung injury caused by aortic ischemia-reperfusion in rats. Twenty-one rats were divided into three groups, one receiving the probiotic and others receiving saline.

After the aorta was clamped, we noticed that those treated with S. boulardii experienced significantly less lung damage and reduced oxidative stress. This suggests the probiotic helps lower inflammation and oxidative stress markers, potentially leading to better outcomes in cardiovascular procedures.
7
Reduced remnant lipoprotein observed
We investigated how the probiotic yeast Saccharomyces boulardii affects blood cholesterol levels in adults with high cholesterol. In this single-arm, open-label pilot study, twelve participants took a specified dose of S. boulardii for eight weeks. While we monitored various cholesterol levels and cardiovascular health markers, results showed a noteworthy reduction in remnant lipoprotein, which could play a role in preventing coronary artery disease. However, overall cholesterol levels did not significantly change during the study.
7
Cardiovascular benefits of yeast compound
We explored how carboxymethyl-glucan, a compound from yeast, impacts heart health in hypertensive rats. Rats were divided into groups, with some receiving carboxymethyl-glucan for four weeks while others received a placebo.

Results showed that carboxymethyl-glucan improved vascular function and decreased platelet aggregation, especially at a high dose. However, it didn’t lower levels of harmful molecules called reactive oxygen species, indicating it may not fully protect against all cardiovascular issues.

Overall, this compound shows promise in helping to manage hypertension and related complications.

References

  1. Dinu LD, Gatea F, Matei F, Banciu C, Vamanu E. Gut Microbiota Modulation by Selenium and Zinc Enrichment Postbiotic on Dysbiosis Associated with Hypertension. Curr Vasc Pharmacol. 2024;22:365. 10.2174/0115701611290537240509061549
  2. Durmaz S, Kurtoğlu T, Barbarus E, Çetin NK, Yılmaz M, et al. Probiotic Saccharomyces boulardii Alleviates Lung Injury by Reduction of Oxidative Stress and Cytokine Response Induced by Supraceliac Aortic Ischemia-Reperfusion Injury in Rats. Braz J Cardiovasc Surg. 2021;36:515. 10.21470/1678-9741-2020-0153
  3. Molska M, Reguła J, Rudzińska M, Świeca M. Fatty acids profile, atherogenic and thrombogenic health lipid indices of lyophilized buckwheat sprouts modified with the addition of Saccharomyces cerevisiae var. boulardii. Acta Sci Pol Technol Aliment. 2020;19:483. 10.17306/J.AFS.0866
  4. Briand F, Sulpice T, Giammarinaro P, Roux X. changes lipidemic profile and gut microbiota in a hamster hypercholesterolemic model. Benef Microbes. 2019;10:555. 10.3920/BM2018.0134
  5. Ryan JJ, Hanes DA, Schafer MB, Mikolai J, Zwickey H. Effect of the Probiotic Saccharomyces boulardii on Cholesterol and Lipoprotein Particles in Hypercholesterolemic Adults: A Single-Arm, Open-Label Pilot Study. J Altern Complement Med. 2015;21:288. 10.1089/acm.2014.0063
  6. Bezerra LS, Magnani M, Pimentel TC, de Oliveira JCPL, Freire FMS, et al. Yeast carboxymethyl-glucan improves endothelial function and inhibits platelet aggregation in spontaneously hypertensive rats. Food Funct. 2022;13:5406. 10.1039/d1fo03492h
  7. Roshanravan N, Koche Ghazi MK, Ghaffari S, Naemi M, Alamdari NM, et al. Sodium selenite and Se-enriched yeast supplementation in atherosclerotic patients: Effects on the expression of pyroptosis-related genes and oxidative stress status. Nutr Metab Cardiovasc Dis. 2022;32:1528. 10.1016/j.numecd.2022.02.014
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