Last update
3/27/2026

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.4
USERS' SCORE
Good
Based on 10 Reviews
8
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Saccharomyces boulardii(an S. cerevisiae Strain)
250 mg(5 Billion CFU)
MOS Yeast Fraction(Min. 35% Manno-oligosaccharides [MOS]) (S. cerevisiae)
200 mg
📅 Last updated:

Top Medical Research Studies

9
Saccharomyces boulardii helps atopic dermatitis
We examined how Saccharomyces boulardii might help with atopic dermatitis (AD), a challenging allergic condition. In a study with mice, S. boulardii was given either before or during the induction of AD-like symptoms.

This probiotic treatment showed promising results, reducing inflammation, improving skin and colon health, and lowering certain harmful blood markers. The study highlighted how S. boulardii can modulate inflammatory responses, suggesting it might be a useful support therapy for managing AD symptoms.
Read More
We explored how perinatal administration of Saccharomyces cerevisiae UFMG A-905 could help prevent asthma in mouse offspring. This study involved various groups of mice receiving the yeast at different stages: before conception, during pregnancy, or only during lactation.

Our results showed that those exposed to S. cerevisiae exhibited significantly less airway hyperresponsiveness and lower levels of certain inflammatory markers compared to those that didn’t receive the treatment. Notably, the greatest protection occurred when the yeast was given during lactation.

Overall, it seems that S. cerevisiae UFMG A-905 shows promise in the management of asthma, especially when administered early in the offspring's development.
Read More
8
Probiotic aids allergic asthma management
We explored the effects of Saccharomyces boulardii on allergic asthma in a mouse model. The study revealed that S. boulardii improved inflammation and lung damage, while also restoring gut microbiota and metabolic balance.

By analyzing gut microbiota and metabolites, we found that S. boulardii up-regulated METTL3, playing a key role in alleviating symptoms. This suggests that probiotics like S. boulardii could offer new strategies to tackle allergic asthma through healthier gut dynamics.
Read More

Most Useful Reviews

9
Permanent change
32 people found this helpful
My condition has changed permanently for the better. I previously suffered from food allergies and IBS after a trip to Mexico. Despite numerous treatments, nothing worked long-term until being on Metagenics Bactin AR/BR for SIBO. This eliminated my food allergies, and following that, this product made a tremendous difference.
Read More
9
Alleviates allergy issues
1 people found this helpful
An outstanding product! This probiotic helped me immensely with my allergy issues in a short time. Since I started it, my histamine problems have improved significantly, and I will definitely purchase it again.
Read More
6
Consistent relief
32 people found this helpful
As an IBS and Candida sufferer, I found relief with this probiotic formula recommended by my naturopathic doctor. It helped a woman allergic to everything except spinach, and I was similarly impressed by how my system adapted. As my gut balanced, my immunity strengthened, and consequently, so did my allergies. I suggest starting slowly to help the body adjust.
Read More

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Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 7 Researches
8.4
  • All Researches
9
Saccharomyces boulardii helps atopic dermatitis
We examined how Saccharomyces boulardii might help with atopic dermatitis (AD), a challenging allergic condition. In a study with mice, S. boulardii was given either before or during the induction of AD-like symptoms.

This probiotic treatment showed promising results, reducing inflammation, improving skin and colon health, and lowering certain harmful blood markers. The study highlighted how S. boulardii can modulate inflammatory responses, suggesting it might be a useful support therapy for managing AD symptoms.
Read More
9
Saccharomyces boulardii enhances allergy treatment
We explored the impact of combining Saccharomyces boulardii with cetirizine hydrochloride in treating allergic rhinitis in children. In a study involving 90 children, we divided them into two groups: one received only cetirizine, while the other was given both medications.

After four weeks, results showed that the group using Saccharomyces boulardii experienced a significantly higher rate of symptom improvement and better changes in immune markers compared to the control group. The combined treatment had an impressive 91.11% effectiveness rate compared to 68.89% for cetirizine alone, suggesting that this probiotic may enhance allergy management for children.
Read More
We explored how perinatal administration of Saccharomyces cerevisiae UFMG A-905 could help prevent asthma in mouse offspring. This study involved various groups of mice receiving the yeast at different stages: before conception, during pregnancy, or only during lactation.

Our results showed that those exposed to S. cerevisiae exhibited significantly less airway hyperresponsiveness and lower levels of certain inflammatory markers compared to those that didn’t receive the treatment. Notably, the greatest protection occurred when the yeast was given during lactation.

Overall, it seems that S. cerevisiae UFMG A-905 shows promise in the management of asthma, especially when administered early in the offspring's development.
Read More
8
Probiotic aids allergic asthma management
We explored the effects of Saccharomyces boulardii on allergic asthma in a mouse model. The study revealed that S. boulardii improved inflammation and lung damage, while also restoring gut microbiota and metabolic balance.

By analyzing gut microbiota and metabolites, we found that S. boulardii up-regulated METTL3, playing a key role in alleviating symptoms. This suggests that probiotics like S. boulardii could offer new strategies to tackle allergic asthma through healthier gut dynamics.
Read More
8
Saccharomyces boulardii shows partial benefits
We explored how a symbiotic preparation with S. boulardii lysate affects gut permeability linked to allergies. In our study with Sprague Dawley rats, stress led to increased gut permeability and significant changes in intestinal structure. However, this stress-induced damage was partly counteracted by the KC-1317 preparation. Although the treatment helped maintain some intestinal health markers, it did not fully restore the altered gut hormone levels caused by stress. Overall, while some benefits were observed, the impact of S. boulardii on allergy-related gut issues remains limited.
Read More

User Reviews

USERS' SCORE
Good
Based on 10 Reviews
8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Permanent change
32 people found this helpful
My condition has changed permanently for the better. I previously suffered from food allergies and IBS after a trip to Mexico. Despite numerous treatments, nothing worked long-term until being on Metagenics Bactin AR/BR for SIBO. This eliminated my food allergies, and following that, this product made a tremendous difference.
Read More
9
Alleviates allergy issues
1 people found this helpful
An outstanding product! This probiotic helped me immensely with my allergy issues in a short time. Since I started it, my histamine problems have improved significantly, and I will definitely purchase it again.
Read More
6
Consistent relief
32 people found this helpful
As an IBS and Candida sufferer, I found relief with this probiotic formula recommended by my naturopathic doctor. It helped a woman allergic to everything except spinach, and I was similarly impressed by how my system adapted. As my gut balanced, my immunity strengthened, and consequently, so did my allergies. I suggest starting slowly to help the body adjust.
Read More
9
Helps digestion and allergies
1 people found this helpful
Great price for these capsules! They are lactose-free and lack unnecessary fillers, which is crucial as I am treating my child's allergies. They significantly aid digestion and protein absorption!
Read More
9
Restores intestines
1 people found this helpful
It works! These capsules helped restore my intestines alongside probiotics and reduced my allergies effectively.
Read More

Frequently Asked Questions

9
Alleviates allergy issues
1 people found this helpful
An outstanding product! This probiotic helped me immensely with my allergy issues in a short time. Since I started it, my histamine problems have improved significantly, and I will definitely purchase it again.
7.5
Improved immunity
1 people found this helpful
My saviour for allergies! I previously took Eubikor but switched to these capsules with plantain fibre, which work far better. One saccharomycete tablet and a spoon of plantain powder have significantly improved my immune response.
7.5
Effective for allergies
2 people found this helpful
I adore the impact this product has. A doctor recommended it alongside other additives during my battle with allergies. I have purchased it several times, and it works well.
8
Probiotic aids allergic asthma management
We explored the effects of Saccharomyces boulardii on allergic asthma in a mouse model. The study revealed that S. boulardii improved inflammation and lung damage, while also restoring gut microbiota and metabolic balance.

By analyzing gut microbiota and metabolites, we found that S. boulardii up-regulated METTL3, playing a key role in alleviating symptoms. This suggests that probiotics like S. boulardii could offer new strategies to tackle allergic asthma through healthier gut dynamics.
9
Saccharomyces boulardii enhances allergy treatment
We explored the impact of combining Saccharomyces boulardii with cetirizine hydrochloride in treating allergic rhinitis in children. In a study involving 90 children, we divided them into two groups: one received only cetirizine, while the other was given both medications.

After four weeks, results showed that the group using Saccharomyces boulardii experienced a significantly higher rate of symptom improvement and better changes in immune markers compared to the control group. The combined treatment had an impressive 91.11% effectiveness rate compared to 68.89% for cetirizine alone, suggesting that this probiotic may enhance allergy management for children.
8
Saccharomyces boulardii shows partial benefits
We explored how a symbiotic preparation with S. boulardii lysate affects gut permeability linked to allergies. In our study with Sprague Dawley rats, stress led to increased gut permeability and significant changes in intestinal structure. However, this stress-induced damage was partly counteracted by the KC-1317 preparation. Although the treatment helped maintain some intestinal health markers, it did not fully restore the altered gut hormone levels caused by stress. Overall, while some benefits were observed, the impact of S. boulardii on allergy-related gut issues remains limited.

References

  1. Buttar PA, Mazhar MU, Khan JZ, Jamil M, Abid M, et al. Saccharomyces boulardii (CNCM I-745) ameliorates Ovalbumin-induced atopic dermatitis by modulating the NF-κB signaling in skin and colon. Arch Dermatol Res. 2025;317:500. 10.1007/s00403-025-04057-6
  2. Liu D, Hu L, Yang Y, Wang Y, Li Y, et al. Saccharomyces boulardii alleviates allergic asthma by restoring gut microbiota and metabolic homeostasis via up-regulation of METTL3 in an m6A-dependent manner. Immunol Lett. 2024;267:106853. 10.1016/j.imlet.2024.106853
  3. Fang GX, Li Z, Su C, Hu GH. [Clinical observation of saccharomyces boulardii combined with cetirizine hydrochloride in children allergic rhinitis]. Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2017;31:1649. 10.13201/j.issn.1001-1781.2017.21.007
  4. Takadanohara H, Catanzaro R, Chui de H, He F, Yadav H, et al. Beneficial effect of a symbiotic preparation with S. boulardii lysate in mild stress-induced gut hyper-permeability. Acta Biomed. 2012;83:208. PubMed
  5. Sandy CM, Guimarães CC, Fonseca VMB, Nicoli JR, Martins FS, et al. Perinatal administration of Saccharomyces cerevisiae UFMG A-905 prevents asthma development in the offspring of mice. Benef Microbes. 2024;16:125. 10.1163/18762891-bja00044
  6. Singh RG, Garcia-Campayo V, Green JB, Paton N, Saunders JD, et al. Efficacy of a yeast postbiotic on cold/flu symptoms in healthy children: A randomized-controlled trial. Pediatr Res. 2024;96:1739. 10.1038/s41390-024-03331-z
  7. Calazans APCT, Milani TMS, Prata AS, Clerici MTPS, Nicoli JR, et al. A Functional Bread Fermented with UFMG A-905 Prevents Allergic Asthma in Mice. Curr Dev Nutr. 2024;8:102142. 10.1016/j.cdnut.2024.102142
Data last updated:
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