Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 29 Researches
7.6
USERS' SCORE
Moderately Good
Based on 14 Reviews
7.6
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Proprietary Probiotic Blend
134 mg (1 Billion CFU§)
†
Lactobacillus rhamnosus (GR-1®)
Lactobacillus reuteri (RC-14®)
Top Medical Research Studies
9.5
We assessed the effectiveness of a probiotic blend of two Lactobacillus strains in treating diarrhea-predominant irritable bowel syndrome (IBS-D) through a randomized, single-blinded trial. Involving 100 patients, one group received standard IBS treatment while the other added probiotics.
After 12 weeks, both groups experienced symptom relief, but the probiotic group showed a greater decrease in their IBS symptoms. Remarkably, all patients on probiotics either found complete symptom relief or had mild symptoms, compared to over 14% of those on standard treatment who still experienced moderate IBS.
After 12 weeks, both groups experienced symptom relief, but the probiotic group showed a greater decrease in their IBS symptoms. Remarkably, all patients on probiotics either found complete symptom relief or had mild symptoms, compared to over 14% of those on standard treatment who still experienced moderate IBS.
Read More
9
We aimed to understand how Lacticaseibacillus rhamnosus IDCC 3201 (RH 3201) affects irritable bowel syndrome with constipation (IBS-C) through a thorough study. In a randomized, double-blind trial, 30 participants took either RH 3201 or a placebo for 8 weeks.
Those taking RH 3201 experienced significant improvements, including fewer bowel discomforts and reduced bloating issues. We also observed an increase in certain beneficial gut bacteria and a link between specific metabolites and symptom relief. Overall, RH 3201 shows promise as an effective treatment for IBS-C.
Those taking RH 3201 experienced significant improvements, including fewer bowel discomforts and reduced bloating issues. We also observed an increase in certain beneficial gut bacteria and a link between specific metabolites and symptom relief. Overall, RH 3201 shows promise as an effective treatment for IBS-C.
Read More
We evaluated how the probiotic Neobiotic Lactobalance® can help patients with irritable bowel syndrome (IBS) experiencing diarrhea and those suffering from antibiotic-associated diarrhea (AAD). Over a 21-day period, 54 participants took one capsule daily.
The results were promising, as symptoms like abdominal pain and diarrheal disorders significantly improved. Patients experienced a notable drop in symptom severity, and beneficial changes in gut bacteria were also observed.
Overall, Lactobalance® appears to support a healthier gut microbiome and alleviate symptoms for these patients.
The results were promising, as symptoms like abdominal pain and diarrheal disorders significantly improved. Patients experienced a notable drop in symptom severity, and beneficial changes in gut bacteria were also observed.
Overall, Lactobalance® appears to support a healthier gut microbiome and alleviate symptoms for these patients.
Read More
Most Useful Reviews
7.5
Improved bowel movements
5 people found this helpful
A urine test revealed a bacterial reaction, so I began taking this. Although I'm unsure of the long-term effects yet, I prefer to avoid antibiotics if possible and hope Acidophilus will assist. I've experienced an immediate improvement in my bowel movements. For years, I dealt with loose stools and constipation, but now I feel well each day when I drink this. The small grain size makes it easy to consume.
Read More
7.5
Quick bowel relief
5 people found this helpful
Many recommended this probiotic for vaginal inflammation, and I saw a difference just two days in. The discharge has significantly reduced, and it doesn't require refrigeration. They are small, tasteless, and easy to swallow, and I've experienced smooth bowel movements the next morning. I intend to continue taking it for maintenance.
Read More
6
Regulated bowel movements
5 people found this helpful
This is an excellent probiotic for women. I noticed a significant difference after taking them for a couple of weeks. Despite often suffering from insomnia, I slept well during this time. My gut feels better, and my bowel movements are regular without constipation. The tablets are small, easy to swallow, and have no unpleasant aftertaste.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 29 Researches
7.6
- All Researches
9.5
Our evaluation focused on the effectiveness of combining probiotics with trimebutine for treating irritable bowel syndrome (IBS). Through a systematic review of 37 randomized controlled trials involving 4,360 participants, we found that this combination therapy significantly outperformed trimebutine alone.
The effective rate was an impressive 93.5% for those receiving both treatments compared to just 73.8% for trimebutine alone. Notably, while side effects were mild in both groups, the combination therapy displayed a favorable safety profile. This suggests that using specific probiotic strains can enhance the treatment outcome for individuals with IBS.
The effective rate was an impressive 93.5% for those receiving both treatments compared to just 73.8% for trimebutine alone. Notably, while side effects were mild in both groups, the combination therapy displayed a favorable safety profile. This suggests that using specific probiotic strains can enhance the treatment outcome for individuals with IBS.
Read More
9.5
We assessed the effectiveness of a probiotic blend of two Lactobacillus strains in treating diarrhea-predominant irritable bowel syndrome (IBS-D) through a randomized, single-blinded trial. Involving 100 patients, one group received standard IBS treatment while the other added probiotics.
After 12 weeks, both groups experienced symptom relief, but the probiotic group showed a greater decrease in their IBS symptoms. Remarkably, all patients on probiotics either found complete symptom relief or had mild symptoms, compared to over 14% of those on standard treatment who still experienced moderate IBS.
After 12 weeks, both groups experienced symptom relief, but the probiotic group showed a greater decrease in their IBS symptoms. Remarkably, all patients on probiotics either found complete symptom relief or had mild symptoms, compared to over 14% of those on standard treatment who still experienced moderate IBS.
Read More
9
Probiotics support intestinal health
We assessed how a multi-strain probiotic, Serobioma, affects gut health in individuals with Irritable Bowel Syndrome (IBS). This study involved IBS patients and healthy controls, looking at how Serobioma interacts with mucosal mediators from IBS patients' biopsies.
Remarkably, Serobioma improved the integrity of intestinal cell layers affected by IBS mediators, particularly in patients with diarrhea and mixed bowel habits. It successfully countered increased permeability, indicating its potential to support gut barrier function in IBS.
Remarkably, Serobioma improved the integrity of intestinal cell layers affected by IBS mediators, particularly in patients with diarrhea and mixed bowel habits. It successfully countered increased permeability, indicating its potential to support gut barrier function in IBS.
Read More
9
Synbiotic reduced IBS pain effectively
We explored the effects of a new synbiotic combination of chitin-glucan (CG) and NCFM in a rat model of irritable bowel syndrome (IBS).
After nine weeks, we found that both CG and NCFM reduced abdominal pain when used separately, but together, they significantly lessened visceral pain and intestinal inflammation.
Not only did this combination improve pain perception, but it also reduced colon lesions and inflammation markers. Overall, our findings suggest that this synbiotic approach holds promise for alleviating IBS symptoms.
After nine weeks, we found that both CG and NCFM reduced abdominal pain when used separately, but together, they significantly lessened visceral pain and intestinal inflammation.
Not only did this combination improve pain perception, but it also reduced colon lesions and inflammation markers. Overall, our findings suggest that this synbiotic approach holds promise for alleviating IBS symptoms.
Read More
We evaluated how the probiotic Neobiotic Lactobalance® can help patients with irritable bowel syndrome (IBS) experiencing diarrhea and those suffering from antibiotic-associated diarrhea (AAD). Over a 21-day period, 54 participants took one capsule daily.
The results were promising, as symptoms like abdominal pain and diarrheal disorders significantly improved. Patients experienced a notable drop in symptom severity, and beneficial changes in gut bacteria were also observed.
Overall, Lactobalance® appears to support a healthier gut microbiome and alleviate symptoms for these patients.
The results were promising, as symptoms like abdominal pain and diarrheal disorders significantly improved. Patients experienced a notable drop in symptom severity, and beneficial changes in gut bacteria were also observed.
Overall, Lactobalance® appears to support a healthier gut microbiome and alleviate symptoms for these patients.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 14 Reviews
7.6
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Improved bowel movements
5 people found this helpful
A urine test revealed a bacterial reaction, so I began taking this. Although I'm unsure of the long-term effects yet, I prefer to avoid antibiotics if possible and hope Acidophilus will assist. I've experienced an immediate improvement in my bowel movements. For years, I dealt with loose stools and constipation, but now I feel well each day when I drink this. The small grain size makes it easy to consume.
Read More
7.5
Quick bowel relief
5 people found this helpful
Many recommended this probiotic for vaginal inflammation, and I saw a difference just two days in. The discharge has significantly reduced, and it doesn't require refrigeration. They are small, tasteless, and easy to swallow, and I've experienced smooth bowel movements the next morning. I intend to continue taking it for maintenance.
Read More
6
Regulated bowel movements
5 people found this helpful
This is an excellent probiotic for women. I noticed a significant difference after taking them for a couple of weeks. Despite often suffering from insomnia, I slept well during this time. My gut feels better, and my bowel movements are regular without constipation. The tablets are small, easy to swallow, and have no unpleasant aftertaste.
Read More
7.5
Stable bowel health
4 people found this helpful
Though it's pricey, this probiotic has been the best for stabilising my bowels, surpassing other supplements. I started to ease my cystitis symptoms and improve daily comfort. If I miss a dose, the effects quickly revert, reinforcing my decision to maintain it as part of my routine.
Read More
9
Bowel improvement noted
2 people found this helpful
Last year, I suffered repeated bacterial vaginosis leading to pyelonephritis and hospitalisation. To avoid long-term antibiotics, I tried this supplement. Since starting it, my vaginal discharge improved, and unexpectedly, my bowel movements have also enhanced. I used to struggle with hemorrhoids in winter, but I’ve been fine this year. I've realised just how crucial bacterial balance is for health.
Read More
Frequently Asked Questions
7.5
Quick bowel relief
5 people found this helpful
Many recommended this probiotic for vaginal inflammation, and I saw a difference just two days in. The discharge has significantly reduced, and it doesn't require refrigeration. They are small, tasteless, and easy to swallow, and I've experienced smooth bowel movements the next morning. I intend to continue taking it for maintenance.
6
Regulated bowel movements
5 people found this helpful
This is an excellent probiotic for women. I noticed a significant difference after taking them for a couple of weeks. Despite often suffering from insomnia, I slept well during this time. My gut feels better, and my bowel movements are regular without constipation. The tablets are small, easy to swallow, and have no unpleasant aftertaste.
7.5
Improved bowel movements
5 people found this helpful
A urine test revealed a bacterial reaction, so I began taking this. Although I'm unsure of the long-term effects yet, I prefer to avoid antibiotics if possible and hope Acidophilus will assist. I've experienced an immediate improvement in my bowel movements. For years, I dealt with loose stools and constipation, but now I feel well each day when I drink this. The small grain size makes it easy to consume.
7.5
Stable bowel health
4 people found this helpful
Though it's pricey, this probiotic has been the best for stabilising my bowels, surpassing other supplements. I started to ease my cystitis symptoms and improve daily comfort. If I miss a dose, the effects quickly revert, reinforcing my decision to maintain it as part of my routine.
9
Bowel improvement noted
2 people found this helpful
Last year, I suffered repeated bacterial vaginosis leading to pyelonephritis and hospitalisation. To avoid long-term antibiotics, I tried this supplement. Since starting it, my vaginal discharge improved, and unexpectedly, my bowel movements have also enhanced. I used to struggle with hemorrhoids in winter, but I’ve been fine this year. I've realised just how crucial bacterial balance is for health.
7
Enhanced bowel function
10 people found this helpful
I started taking this due to concerns about unpleasant odours. It's effective for my bowel movements; both the smell and my bowel function have significantly improved. While undergoing fertility treatment, I believe this positively affects my vaginal environment, so I've committed to one tablet daily.
6
Smoother movements
I take regular lactobacillus in the morning and before bed, and I've noticed that the symptoms of vaginitis have disappeared, while my bowel movements are now smoother.
2
No improvement
Unfortunately, this probiotic did not help with my bowel movements.
9
Probiotics support intestinal health
We assessed how a multi-strain probiotic, Serobioma, affects gut health in individuals with Irritable Bowel Syndrome (IBS). This study involved IBS patients and healthy controls, looking at how Serobioma interacts with mucosal mediators from IBS patients' biopsies.
Remarkably, Serobioma improved the integrity of intestinal cell layers affected by IBS mediators, particularly in patients with diarrhea and mixed bowel habits. It successfully countered increased permeability, indicating its potential to support gut barrier function in IBS.
Remarkably, Serobioma improved the integrity of intestinal cell layers affected by IBS mediators, particularly in patients with diarrhea and mixed bowel habits. It successfully countered increased permeability, indicating its potential to support gut barrier function in IBS.
8
We conducted a thorough review to assess how different treatments, like probiotics, prebiotics, synbiotics, and fecal microbiota transplantation, affect irritable bowel syndrome (IBS) symptoms.
Our analysis involved 54 studies on probiotics, where we discovered clear improvements in IBS symptoms, particularly with certain strains. However, prebiotics and synbiotics did not demonstrate significant benefits.
The network meta-analysis highlighted that probiotics and fecal microbiota transplantation are promising options for managing IBS, although the best probiotic strain remains uncertain.
Our analysis involved 54 studies on probiotics, where we discovered clear improvements in IBS symptoms, particularly with certain strains. However, prebiotics and synbiotics did not demonstrate significant benefits.
The network meta-analysis highlighted that probiotics and fecal microbiota transplantation are promising options for managing IBS, although the best probiotic strain remains uncertain.
9.5
Our evaluation focused on the effectiveness of combining probiotics with trimebutine for treating irritable bowel syndrome (IBS). Through a systematic review of 37 randomized controlled trials involving 4,360 participants, we found that this combination therapy significantly outperformed trimebutine alone.
The effective rate was an impressive 93.5% for those receiving both treatments compared to just 73.8% for trimebutine alone. Notably, while side effects were mild in both groups, the combination therapy displayed a favorable safety profile. This suggests that using specific probiotic strains can enhance the treatment outcome for individuals with IBS.
The effective rate was an impressive 93.5% for those receiving both treatments compared to just 73.8% for trimebutine alone. Notably, while side effects were mild in both groups, the combination therapy displayed a favorable safety profile. This suggests that using specific probiotic strains can enhance the treatment outcome for individuals with IBS.
5
We examined the effectiveness of Lactobacillus and other probiotics in treating irritable bowel syndrome (IBS) through a thorough review of 82 clinical trials involving over 10,000 patients. The results indicated that while some probiotics, particularly certain Escherichia strains, showed moderate benefits for general symptoms, the effectiveness of Lactobacillus strains was generally rated as low to very low. Importantly, the risk of adverse events did not increase significantly with probiotic use. Overall, evidence supporting probiotics for IBS remains uncertain.
9
Probiotics effective for IBS relief
We aimed to explore the effectiveness of probiotics in managing irritable bowel syndrome (IBS). By reviewing 52 rigorous trials with nearly 6,300 participants, we found that probiotics significantly enhanced overall symptom relief, improved subjective well-being, and alleviated abdominal pain.
Notably, a daily dose of 10 billion cfu seemed particularly beneficial, with effects visible as early as four weeks into treatment. While probiotics demonstrated clear advantages, the roles of prebiotics and synbiotics remain less certain due to limited studies.
Notably, a daily dose of 10 billion cfu seemed particularly beneficial, with effects visible as early as four weeks into treatment. While probiotics demonstrated clear advantages, the roles of prebiotics and synbiotics remain less certain due to limited studies.
7
Lactobacillus rhamnosus shows positive IBS effects
We explored how a mix of Lactobacillus probiotics, including Lactobacillus rhamnosus, could help improve symptoms of irritable bowel syndrome (IBS) in a study involving 113 participants.
Participants took either the probiotic or a placebo for 12 weeks, with results showing that those on the active treatment experienced significant relief in several areas, particularly in managing pain and enhancing quality of life.
The most notable improvements were seen in women and those with diarrhea-predominant IBS. While some subjects reported mild adverse effects, serious complications were absent, confirming the treatment's safety.
Participants took either the probiotic or a placebo for 12 weeks, with results showing that those on the active treatment experienced significant relief in several areas, particularly in managing pain and enhancing quality of life.
The most notable improvements were seen in women and those with diarrhea-predominant IBS. While some subjects reported mild adverse effects, serious complications were absent, confirming the treatment's safety.
9.5
We assessed the effectiveness of a probiotic blend of two Lactobacillus strains in treating diarrhea-predominant irritable bowel syndrome (IBS-D) through a randomized, single-blinded trial. Involving 100 patients, one group received standard IBS treatment while the other added probiotics.
After 12 weeks, both groups experienced symptom relief, but the probiotic group showed a greater decrease in their IBS symptoms. Remarkably, all patients on probiotics either found complete symptom relief or had mild symptoms, compared to over 14% of those on standard treatment who still experienced moderate IBS.
After 12 weeks, both groups experienced symptom relief, but the probiotic group showed a greater decrease in their IBS symptoms. Remarkably, all patients on probiotics either found complete symptom relief or had mild symptoms, compared to over 14% of those on standard treatment who still experienced moderate IBS.
References
- Barbaro MR, Bianco F, Cremon C, Marasco G, Stanghellini V, et al. A Probiotic Mixture of LR 32, BL 04, and BB 536 Counteracts the Increase in Permeability Induced by the Mucosal Mediators of Irritable Bowel Syndrome by Acting on Zonula Occludens 1. Int J Mol Sci. 2025;26. doi:10.3390/ijms26062656
- Wei JJ, Zhang PH, Yang ZY, Liu LP, Lian TT, et al. Colonoscopic administration of probiotics to treat irritable bowel syndrome with predominant diarrhea: a randomized placebo-controlled clinical trial. Surg Endosc. 2025;39:1893. doi:10.1007/s00464-025-11542-6
- Gąsiorowska A, Romanowski M, Walecka-Kapica E, Kaczka A, Chojnacki C, et al. Efficacy and Safety of a Mixture of Microencapsulated Sodium Butyrate, Probiotics, and Short Chain Fructooligosaccharides in Patients with Irritable Bowel Syndrome-A Randomized, Double-Blind, Placebo-Controlled Study. J Clin Med. 2024;14. doi:10.3390/jcm14010006
- Yu QX, Wang DD, Dong PJ, Zheng LH. Probiotics Combined With Trimebutine for the Treatment of Irritable Bowel Syndrome Patients: A Systematic Review and Meta-Analysis. J Gastroenterol Hepatol. 2025;40:677. doi:10.1111/jgh.16858
- Capirchio L, Rousseaux C, Dubuquoy C, Ouwehand AC, Maquet V, et al. A Synbiotic Combining Chitin-Glucan and NCFM Induces a Colonic Molecular Signature Soothing Intestinal Pain and Inflammation in an Animal Model of IBS. Int J Mol Sci. 2024;25. doi:10.3390/ijms251910732
- Biskou O, Walter S, Israelsen H, Winberg ME, Bednarska O, et al. ReFerm: a postbiotic fermented oat gruel composition is reducing mast cell degranulation in the colon of patients with irritable bowel syndrome. Front Med (Lausanne). 2024;11:1408623. doi:10.3389/fmed.2024.1408623
- Wu Y, Li Y, Zheng Q, Li L. The Efficacy of Probiotics, Prebiotics, Synbiotics, and Fecal Microbiota Transplantation in Irritable Bowel Syndrome: A Systematic Review and Network Meta-Analysis. Nutrients. 2024;16. doi:10.3390/nu16132114
- Zhang H, Xia Y, Wang G, Xiong Z, Wei G, et al. AR495 improves colonic transport hyperactivity in irritable bowel syndrome through tryptophan metabolism. Food Funct. 2024;15:7416. doi:10.1039/d4fo01087f
- Torres-Maravilla E, Carvalho FA, Holowacz S, Delannoy J, Lenoir L, et al. Screening of probiotic strains to improve visceral hypersensitivity in irritable bowel syndrome by using in vitro and in vivo approaches. Benef Microbes. 2024;15:293. doi:10.1163/18762891-bja00006
- Sarkawi M, Raja Ali RA, Abdul Wahab N, Abdul Rathi ND, Mokhtar NM. A randomized, double-blinded, placebo-controlled clinical trial on Lactobacillus-containing cultured milk drink as adjuvant therapy for depression in irritable bowel syndrome. Sci Rep. 2024;14:9478. doi:10.1038/s41598-024-60029-2
- Jouët P, Altman C, Bruley DES Varannes S, Juhel C, Henri F. Probiotics plus vitamin D in irritable bowel syndrome: a prospective multicentric non-interventional study. Minerva Gastroenterol (Torino). 2024;70:332. doi:10.23736/S2724-5985.24.03581-2
- Shanshal SA, Alsaaty MH, Al-Qazaz H, Al-Zidan RN. Two Lactobacilli strains as adjuvant therapy in the management of irritable bowel syndrome: a randomized control trial. Ceska Slov Farm. 2024;72:233.
- Chang YH, Choi YJ, Shin CM, Moon JS, Kim TY, et al. Efficacy of Quadruple-coated Probiotics in Patients With Irritable Bowel Syndrome: A Randomized, Double-blind, Placebo-controlled, Parallel-group Study. J Neurogastroenterol Motil. 2024;30:73. doi:10.5056/jnm23036
- Drozdov VN, Shikh EV, Astapovskii AA, Khalaidzheva KN, Solovieva SA, et al. [Clinical efficacy of a modern probiotic for the correction of intestinal microflora in patients with irritable bowel syndrome with diarrhea and antibiotic-associated diarrhea]. Vopr Pitan. 2023;92:92. doi:10.33029/0042-8833-2023-92-4-92-103
- Zhang WX, Shi LB, Zhou MS, Wu J, Shi HY. Efficacy of probiotics, prebiotics and synbiotics in irritable bowel syndrome: a systematic review and meta-analysis of randomized, double-blind, placebo-controlled trials. J Med Microbiol. 2023;72. doi:10.1099/jmm.0.001758
- Goodoory VC, Khasawneh M, Black CJ, Quigley EMM, Moayyedi P, et al. Efficacy of Probiotics in Irritable Bowel Syndrome: Systematic Review and Meta-analysis. Gastroenterology. 2023;165:1206. doi:10.1053/j.gastro.2023.07.018
- Kwon H, Nam EH, Kim H, Jo H, Bang WY, et al. Effect of Lacticaseibacillus rhamnosus IDCC 3201 on irritable bowel syndrome with constipation: a randomized, double-blind, and placebo-controlled trial. Sci Rep. 2024;14:22384. doi:10.1038/s41598-024-72887-x
- Zhang L, Ni X, Jiang M, Du M, Zhang S, et al. Strains for Alleviation of Irritable Bowel Disease and Chronic Fatigue Syndrome. Microorganisms. 2024;12. doi:10.3390/microorganisms12061081
- Skrzydło-Radomańska B, Prozorow-Król B, Cichoż-Lach H, Majsiak E, Bierła JB, et al. The Effectiveness of Synbiotic Preparation Containing and Probiotic Strains and Short Chain Fructooligosaccharides in Patients with Diarrhea Predominant Irritable Bowel Syndrome-A Randomized Double-Blind, Placebo-Controlled Study. Nutrients. 2020;12. doi:10.3390/nu12071999
- Bonfrate L, Di Palo DM, Celano G, Albert A, Vitellio P, et al. Effects of Bifidobacterium longum BB536 and Lactobacillus rhamnosus HN001 in IBS patients. Eur J Clin Invest. 2020;50:e13201. doi:10.1111/eci.13201
- Ding FCL, Karkhaneh M, Zorzela L, Jou H, Vohra S. Probiotics for paediatric functional abdominal pain disorders: A rapid review. Paediatr Child Health. 2019;24:383. doi:10.1093/pch/pxz036
- Nocerino R, Di Costanzo M, Bedogni G, Cosenza L, Maddalena Y, et al. Dietary Treatment with Extensively Hydrolyzed Casein Formula Containing the Probiotic Lactobacillus rhamnosus GG Prevents the Occurrence of Functional Gastrointestinal Disorders in Children with Cow's Milk Allergy. J Pediatr. 2019;213:137. doi:10.1016/j.jpeds.2019.06.004
- Hojsak I. Probiotics in Functional Gastrointestinal Disorders. Adv Exp Med Biol. 2019;1125:121. doi:10.1007/5584_2018_321
- Han X, Lee A, Huang S, Gao J, Spence JR, et al. Lactobacillus rhamnosus GG prevents epithelial barrier dysfunction induced by interferon-gamma and fecal supernatants from irritable bowel syndrome patients in human intestinal enteroids and colonoids. Gut Microbes. 2019;10:59. doi:10.1080/19490976.2018.1479625
- Preston K, Krumian R, Hattner J, de Montigny D, Stewart M, et al. Lactobacillus acidophilus CL1285, Lactobacillus casei LBC80R and Lactobacillus rhamnosus CLR2 improve quality-of-life and IBS symptoms: a double-blind, randomised, placebo-controlled study. Benef Microbes. 2018;9:697. doi:10.3920/BM2017.0105
- Wegh CAM, Benninga MA, Tabbers MM. Effectiveness of Probiotics in Children With Functional Abdominal Pain Disorders and Functional Constipation: A Systematic Review. J Clin Gastroenterol. 2018;52 Suppl 1, Proceedings from the 9th Probiotics, Prebiotics and New Foods, Nutraceuticals and Botanicals for Nutrition & Human and Microbiota Health Meeting, held in Rome, Italy from September 10 to 12, 2017:S10. doi:10.1097/MCG.0000000000001054
- Darbaky Y, Evrard B, Patrier S, Falenta J, Garcin S, et al. Oral probiotic treatment of Lactobacillus rhamnosus Lcr35 prevents visceral hypersensitivity to a colonic inflammation and an acute psychological stress. J Appl Microbiol. 2017;122:188. doi:10.1111/jam.13320
- Yoon H, Park YS, Lee DH, Seo JG, Shin CM, et al. Effect of administering a multi-species probiotic mixture on the changes in fecal microbiota and symptoms of irritable bowel syndrome: a randomized, double-blind, placebo-controlled trial. J Clin Biochem Nutr. 2015;57:129. doi:10.3164/jcbn.15-14
- Cruchet S, Furnes R, Maruy A, Hebel E, Palacios J, et al. The use of probiotics in pediatric gastroenterology: a review of the literature and recommendations by Latin-American experts. Paediatr Drugs. 2015;17:199. doi:10.1007/s40272-015-0124-6
