Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 22 Researches
7.6
USERS' SCORE
Good
Based on 28 Reviews
8.2
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Proprietary Probiotic Blend
134 mg (1 Billion CFU§)
†
Lactobacillus rhamnosus (GR-1®)
Lactobacillus reuteri (RC-14®)
Top Medical Research Studies
9
We investigated the effects of Lactobacillus reuteri on bone health in menopausal mice. Our findings revealed that this probiotic significantly curtails bone loss linked to estrogen deficiency.
Specifically, L. reuteri treatment led to lower levels of bone resorption markers and reduced the factors that promote osteoclast formation, which are responsible for bone deterioration.
These results suggest that L. reuteri not only helps maintain bone density but also positively influences gut health during menopause, showcasing its potential as an accessible method for women to combat post-menopausal bone loss.
Specifically, L. reuteri treatment led to lower levels of bone resorption markers and reduced the factors that promote osteoclast formation, which are responsible for bone deterioration.
These results suggest that L. reuteri not only helps maintain bone density but also positively influences gut health during menopause, showcasing its potential as an accessible method for women to combat post-menopausal bone loss.
Read More
9
Probiotic may stabilize estrogen levels
We examined whether a probiotic containing the strain KABP052 could help stabilize estrogen levels in peri- and postmenopausal women. In a thorough randomized, double-blind study, we compared women taking the probiotic to those given a placebo.
Over 12 weeks, those who received KABP052 showed notably higher estradiol and estrone levels, suggesting that this probiotic can effectively modulate estrogen during menopause. This promising finding opens new avenues for using probiotics to support menopausal health.
Over 12 weeks, those who received KABP052 showed notably higher estradiol and estrone levels, suggesting that this probiotic can effectively modulate estrogen during menopause. This promising finding opens new avenues for using probiotics to support menopausal health.
Read More
9
We investigated how orally administered probiotics, particularly Lactobacillus rhamnosus, can impact the vaginal flora of postmenopausal women. In a randomized, double-blind study, participants received either probiotic capsules or a placebo for 14 days.
Our findings revealed that 60% of the women taking the probiotics experienced a significant improvement in their vaginal flora, compared to just 16% in the placebo group. This suggests that Lactobacillus rhamnosus may effectively support vaginal health during menopause.
Our findings revealed that 60% of the women taking the probiotics experienced a significant improvement in their vaginal flora, compared to just 16% in the placebo group. This suggests that Lactobacillus rhamnosus may effectively support vaginal health during menopause.
Read More
Most Useful Reviews
9
Vaginal burning treatment
26 people found this helpful
I'm cured, and I will take this product forever. This stuff is fantastic! At 66, I started suffering from severe vaginal burning. It felt unbearable. Avoiding doctors, I did some research thinking it might be a yeast infection. Fem-Dophilus was recommended, but it took too long to arrive, so I bought it at Whole Foods. After 10 days of treatment (including vaginal insertion 2x daily for 3 days), I was cured. I will continue using this daily for life to avoid that misery. It’s a safe product with no scary chemicals, but it must be kept cold.
Read More
9
Reduced secretions
17 people found this helpful
Excellent! I used this for my mother during menopause to help control secretions. Along with evening primrose oil for dry skin and hot flashes, this product significantly reduced secretions. I take two tablets daily after a meal and plan to continue this course. I hope it benefits others as well.
Read More
9
Moisture increased
9 people found this helpful
After menopause, I experienced dryness and discomfort around my vagina. Within a week of taking this supplement, the odour vanished, and I felt moisture return. If I forget to take it, the smell reappears, making this supplement essential. It appears I needed the lactic acid bacteria it provides.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 22 Researches
7.6
- All Researches
9
Probiotics improve post-menopausal vaginal health
We explored the potential of probiotics to enhance vaginal health in post-menopausal women. Through a clinical trial involving 50 participants aged 45 to 65, we administered a daily probiotic supplement for 28 days.
The results were promising, showing a noteworthy reduction in menopause-related symptoms, including a 50% improvement in vaginal well-being. Remarkably, we also noted significant decreases in inflammatory markers alongside a positive shift in vaginal microbiota, with increased lactobacilli.
Our findings suggest that these specific probiotic strains can effectively support post-menopausal women’s health.
The results were promising, showing a noteworthy reduction in menopause-related symptoms, including a 50% improvement in vaginal well-being. Remarkably, we also noted significant decreases in inflammatory markers alongside a positive shift in vaginal microbiota, with increased lactobacilli.
Our findings suggest that these specific probiotic strains can effectively support post-menopausal women’s health.
Read More
9
Lactobacillus effective for vaginal health
We evaluated the effects of VagiBIOM, a Lactobacillus-based vaginal suppository, on vaginal health among peri- and premenopausal women facing bacterial vaginosis (BV). In a randomized, double-blind, placebo-controlled trial with 66 participants, we measured changes in vaginal pH and health after 4 weeks of treatment.
Results showed significant improvements in vaginal health index scores and reductions in vaginal pH and itching symptoms. Notably, two Lactobacillus species identified in the treatment group indicated enhanced vaginal microbiome diversity. VagiBIOM appears effective in relieving BV-related symptoms in women experiencing menopause.
Results showed significant improvements in vaginal health index scores and reductions in vaginal pH and itching symptoms. Notably, two Lactobacillus species identified in the treatment group indicated enhanced vaginal microbiome diversity. VagiBIOM appears effective in relieving BV-related symptoms in women experiencing menopause.
Read More
9
Probiotic may stabilize estrogen levels
We examined whether a probiotic containing the strain KABP052 could help stabilize estrogen levels in peri- and postmenopausal women. In a thorough randomized, double-blind study, we compared women taking the probiotic to those given a placebo.
Over 12 weeks, those who received KABP052 showed notably higher estradiol and estrone levels, suggesting that this probiotic can effectively modulate estrogen during menopause. This promising finding opens new avenues for using probiotics to support menopausal health.
Over 12 weeks, those who received KABP052 showed notably higher estradiol and estrone levels, suggesting that this probiotic can effectively modulate estrogen during menopause. This promising finding opens new avenues for using probiotics to support menopausal health.
Read More
9
We investigated how orally administered probiotics, particularly Lactobacillus rhamnosus, can impact the vaginal flora of postmenopausal women. In a randomized, double-blind study, participants received either probiotic capsules or a placebo for 14 days.
Our findings revealed that 60% of the women taking the probiotics experienced a significant improvement in their vaginal flora, compared to just 16% in the placebo group. This suggests that Lactobacillus rhamnosus may effectively support vaginal health during menopause.
Our findings revealed that 60% of the women taking the probiotics experienced a significant improvement in their vaginal flora, compared to just 16% in the placebo group. This suggests that Lactobacillus rhamnosus may effectively support vaginal health during menopause.
Read More
9
We explored how Limosilactobacillus reuteri affects bone loss related to menopause by studying its impact in ovariectomized mice. Our research involved a control group and two treatment groups to assess both live and heat-killed forms of this probiotic.
We observed that both forms of L. reuteri significantly improved bone density compared to the untreated ovariectomized group. However, we found no differences in specific gene expressions related to inflammation, indicating that the probiotic's protective effects on bone were independent of these particular pathways.
Overall, L. reuteri showed promise as a potential treatment for managing bone health during menopause.
We observed that both forms of L. reuteri significantly improved bone density compared to the untreated ovariectomized group. However, we found no differences in specific gene expressions related to inflammation, indicating that the probiotic's protective effects on bone were independent of these particular pathways.
Overall, L. reuteri showed promise as a potential treatment for managing bone health during menopause.
Read More
User Reviews
USERS' SCORE
Good
Based on 28 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
9
Vaginal burning treatment
26 people found this helpful
I'm cured, and I will take this product forever. This stuff is fantastic! At 66, I started suffering from severe vaginal burning. It felt unbearable. Avoiding doctors, I did some research thinking it might be a yeast infection. Fem-Dophilus was recommended, but it took too long to arrive, so I bought it at Whole Foods. After 10 days of treatment (including vaginal insertion 2x daily for 3 days), I was cured. I will continue using this daily for life to avoid that misery. It’s a safe product with no scary chemicals, but it must be kept cold.
Read More
9
Reduced secretions
17 people found this helpful
Excellent! I used this for my mother during menopause to help control secretions. Along with evening primrose oil for dry skin and hot flashes, this product significantly reduced secretions. I take two tablets daily after a meal and plan to continue this course. I hope it benefits others as well.
Read More
9
Moisture increased
9 people found this helpful
After menopause, I experienced dryness and discomfort around my vagina. Within a week of taking this supplement, the odour vanished, and I felt moisture return. If I forget to take it, the smell reappears, making this supplement essential. It appears I needed the lactic acid bacteria it provides.
Read More
7.5
Prevention tool
9 people found this helpful
I had both cystitis and vaginitis simultaneously and wanted to avoid recurrence, so I quickly purchased this. I take one capsule morning and evening, and I am currently doing well without any recurrence. As noted in other reviews, it truly enhances my comfort. As I'm approaching menopause, this has become essential for prevention.
Read More
9
Odour resolved
6 people found this helpful
The unpleasant smell has disappeared since I started taking this small, easy-to-swallow capsule. After learning about the impact of menopause on my vaginal flora, I was relieved to find that this supplement worked. It not only improved the odour but may also benefit my oral health, which I maintain proactively.
Read More
Frequently Asked Questions
7.5
Odour reduction
3 people found this helpful
The unpleasant odour from my genitals disappeared within 2-3 days! At 48, I was anxious about the stronger smell of my vaginal discharge as I approached menopause. Despite trying to improve my health, the smell persisted until I took this supplement. Now, if I feel the smell returning, taking an additional pill helps immediately. I highly recommend it!
9
Inflammation relief
3 people found this helpful
Navigating menopause has brought discomfort in my private areas that necessitated antibiotics and suppositories. However, I decided against that route and tried this product. After a week, my situation improved considerably; the doctor noted a significant reduction in inflammation. It enhanced my quality of life, and I recommend it to others.
9
Odour manageable
4 people found this helpful
I began taking this due to concerns about odour as I entered menopause. It’s purported that vaginal lactic acid bacteria can help restore good bacteria levels. After a month, the odour is no longer an issue for me. The tablets are small and easy to ingest.
7.5
Reduced dryness
3 people found this helpful
Suffering from dryness and itching post-menopause, I started this supplement and found that my symptoms gradually diminished. I'm considering continued use for further improvement.
9
Moisture increased
9 people found this helpful
After menopause, I experienced dryness and discomfort around my vagina. Within a week of taking this supplement, the odour vanished, and I felt moisture return. If I forget to take it, the smell reappears, making this supplement essential. It appears I needed the lactic acid bacteria it provides.
7.5
Environment improved
5 people found this helpful
During menopause, I experienced cystitis for two consecutive months, worsened by antibiotics. I sought a supplement to improve my vaginal environment, and after reading reviews, I purchased this one. By the third day of taking it before bed, the smell and itchiness subsided, and I have since avoided cystitis.
4
No significant effect
I switched to this supplement during menopause, but unfortunately, it hasn’t provided significant effects for me, so I will only use it this once.
9
Reduced secretions
17 people found this helpful
Excellent! I used this for my mother during menopause to help control secretions. Along with evening primrose oil for dry skin and hot flashes, this product significantly reduced secretions. I take two tablets daily after a meal and plan to continue this course. I hope it benefits others as well.
7.5
Menopause support
This probiotic pairs well with menopause medication. It significantly improves my condition during menopause.
6
Fertility support
2 people found this helpful
Exceptional quality! I bought it for myself and my sister, who fell pregnant after using it. I advise all women nearing menopause to consider taking this alongside Moringa to aid in fertility.
7.5
Prevention tool
9 people found this helpful
I had both cystitis and vaginitis simultaneously and wanted to avoid recurrence, so I quickly purchased this. I take one capsule morning and evening, and I am currently doing well without any recurrence. As noted in other reviews, it truly enhances my comfort. As I'm approaching menopause, this has become essential for prevention.
9
Odour eliminated
1 people found this helpful
Femcare is an overseas supplement with small, easy-to-take capsules. I read that it reduces the smell of vaginal discharge post-menopause. After taking it, I was pleased to find the odour disappeared. Once I stopped, the smell returned, so now I take it continuously. I suspect I won’t see further benefits until my intestinal health improves.
7
We investigated how vaginal microbiota, particularly the presence of Lactobacillus, relates to the symptoms of genitourinary syndrome of menopause (GSM) in women. In a study of 96 women, we analyzed their vaginal microbiomes and explored the effects of Lactobacillus capsules on GSM symptoms.
Our findings suggest that imbalances in vaginal bacteria could play a role in GSM, especially regarding genital and sexual symptoms. We believe Lactobacillus may offer a non-hormonal treatment option for those experiencing such symptoms during menopause.
Our findings suggest that imbalances in vaginal bacteria could play a role in GSM, especially regarding genital and sexual symptoms. We believe Lactobacillus may offer a non-hormonal treatment option for those experiencing such symptoms during menopause.
9
Probiotics improve post-menopausal vaginal health
We explored the potential of probiotics to enhance vaginal health in post-menopausal women. Through a clinical trial involving 50 participants aged 45 to 65, we administered a daily probiotic supplement for 28 days.
The results were promising, showing a noteworthy reduction in menopause-related symptoms, including a 50% improvement in vaginal well-being. Remarkably, we also noted significant decreases in inflammatory markers alongside a positive shift in vaginal microbiota, with increased lactobacilli.
Our findings suggest that these specific probiotic strains can effectively support post-menopausal women’s health.
The results were promising, showing a noteworthy reduction in menopause-related symptoms, including a 50% improvement in vaginal well-being. Remarkably, we also noted significant decreases in inflammatory markers alongside a positive shift in vaginal microbiota, with increased lactobacilli.
Our findings suggest that these specific probiotic strains can effectively support post-menopausal women’s health.
7
Lactobacillus and bone health study
We are investigating how lactobacillus strains impact bone health in early postmenopausal women. In a carefully designed double-blind, randomized controlled trial, 124 participants will receive daily doses of either probiotics or a placebo over a 12-month period.
Our main focus is on changes in bone mineral density and the structure of bone. While previous animal studies have shown promise, it's crucial to see if these benefits hold true in humans. We hope to shed light on the potential of probiotics as a strategy to safeguard against osteoporosis.
Our main focus is on changes in bone mineral density and the structure of bone. While previous animal studies have shown promise, it's crucial to see if these benefits hold true in humans. We hope to shed light on the potential of probiotics as a strategy to safeguard against osteoporosis.
References
- Sandrine MNY, Michel BG, Bibi-Farouck AO, Ngo Bahebeck P, Emmanuel OP, et al. In silico molecular docking and predictive ADME properties, in vitro antioxidant scavenging capacities, and in vivo pharmacological activities to study the potential of Pterocarpus mildbraedii's Harms (Fabaceae) in preventing vaginal dysbiosis and risk factors for cardiovascular disease in an estropause rat model. Fitoterapia. 2025;183:106496. doi:10.1016/j.fitote.2025.106496
- Dabeer S, Tripathi AK, Weiss D, Vikulina T, Ofotokun I, et al. Combined Sequential Antiretroviral Therapy-Induced Immune Reconstitution Bone Loss and Estrogen Deficiency Bone Loss are Cumulative in Mice Models. J Infect Dis. 2024. doi:10.1093/infdis/jiae643
- Zeng Q, Shu H, Pan H, Zhang Y, Fan L, et al. Associations of vaginal microbiota with the onset, severity, and type of symptoms of genitourinary syndrome of menopause in women. Front Cell Infect Microbiol. 2024;14:1402389. doi:10.3389/fcimb.2024.1402389
- De Leo V, Governini L, Ponchia R, Recalcati D, Murina F. Effectiveness of Combination of Tibolone and Plus Lactoferrin in Postmenopausal Women with Vulvar Vestibular Pain: A Preliminary Report. Nutrients. 2024;16. doi:10.3390/nu16142378
- Harahap IA, Moszak M, Czlapka-Matyasik M, Skrypnik K, Bogdański P, et al. Effects of daily probiotic supplementation with on calcium status, bone metabolism biomarkers, and bone mineral density in postmenopausal women: a controlled and randomized clinical study. Front Nutr. 2024;11:1401920. doi:10.3389/fnut.2024.1401920
- Byrne EH, Song H, Srinivasan S, Fredricks DN, Reed SD, et al. Association between vaginal microbiota and vaginal inflammatory immune markers in postmenopausal women. Menopause. 2024;31:575. doi:10.1097/GME.0000000000002362
- Resciniti SM, Biesiekierski JR, Ghasem-Zadeh A, Moschonis G. The Effectiveness of a Lactobacilli-Based Probiotic Food Supplement on Bone Mineral Density and Bone Metabolism in Australian Early Postmenopausal Women: Protocol for a Double-Blind Randomized Placebo-Controlled Trial. Nutrients. 2024;16. doi:10.3390/nu16081150
- Vicariotto F, Malfa P, Viciani E, Dell'Atti F, Squarzanti DF, et al. Efficacy of PBS067, subsp. BL050, and LRH020 in the Amelioration of Vaginal Microbiota in Post-Menopausal Women: A Prospective Observational Clinical Trial. Nutrients. 2024;16. doi:10.3390/nu16030402
- Vivekanandan V, Khan ZH, Venugopal G, Musunuru B, Mishra P, et al. VagiBIOM Lactobacillus suppository improves vaginal health index in perimenopausal women with bacterial vaginosis: a randomized control trial. Sci Rep. 2024;14:3317. doi:10.1038/s41598-024-53770-1
- Bayat Z, Damirchi A, Hasannejad-Bibalan M, Babaei P. Metabotropic Effect of Probiotic Supplementation and High-Intensity Interval Training in Menopause-Induced Metabolic Syndrome in Rats. J Menopausal Med. 2023;29:29. doi:10.6118/jmm.22037
- Sawada D, Sugawara T, Hirota T, Nakamura Y. Effects of CP2305 on Mild Menopausal Symptoms in Middle-Aged Women. Nutrients. 2022;14. doi:10.3390/nu14091695
- Bhardwaj A, Sapra L, Madan D, Ahuja V, Sharma HP, et al. Gut-resident Tregs (GTregs) play a pivotal role in maintaining bone health under post-menopausal osteoporotic conditions. J Leukoc Biol. 2025. doi:10.1093/jleuko/qiaf008
- Honda S, Tominaga Y, Espadaler-Mazo J, Huedo P, Aguiló M, et al. Supplementation with a Probiotic Formula Having β-Glucuronidase Activity Modulates Serum Estrogen Levels in Healthy Peri- and Postmenopausal Women. J Med Food. 2024;27:720. doi:10.1089/jmf.2023.k.0320
- Kwak YK, Daroczy K, Colque P, Kühn I, Möllby R, et al. Persistence of Lactobacilli in Postmenopausal Women - A Double-Blind, Randomized, Pilot Study. Gynecol Obstet Invest. 2017;82:144. doi:10.1159/000446946
- Bisanz JE, Seney S, McMillan A, Vongsa R, Koenig D, et al. A systems biology approach investigating the effect of probiotics on the vaginal microbiome and host responses in a double blind, placebo-controlled clinical trial of post-menopausal women. PLoS One. 2014;9:e104511. doi:10.1371/journal.pone.0104511
- Parma M, Dindelli M, Caputo L, Redaelli A, Quaranta L, et al. The role of vaginal Lactobacillus Rhamnosus (Normogin®) in preventing Bacterial Vaginosis in women with history of recurrences, undergoing surgical menopause: a prospective pilot study. Eur Rev Med Pharmacol Sci. 2013;17:1399.
- Petricevic L, Unger FM, Viernstein H, Kiss H. Randomized, double-blind, placebo-controlled study of oral lactobacilli to improve the vaginal flora of postmenopausal women. Eur J Obstet Gynecol Reprod Biol. 2008;141:54. doi:10.1016/j.ejogrb.2008.06.003
- Reid G, Burton J, Hammond JA, Bruce AW. Nucleic acid-based diagnosis of bacterial vaginosis and improved management using probiotic lactobacilli. J Med Food. 2004;7:223.
- Ribeiro JL, Santos TA, Garcia MT, Carvalho BFDC, Esteves JECS, et al. Heat-killed Limosilactobacillus reuteri ATCC PTA 6475 prevents bone loss in ovariectomized mice: A preliminary study. PLoS One. 2024;19:e0304358. doi:10.1371/journal.pone.0304358
- Rahmani D, Faal B, Zali H, Tackallou SH, Niknam Z. The beneficial effects of simultaneous supplementation of Lactobacillus reuteri and calcium fluoride nanoparticles on ovariectomy-induced osteoporosis. BMC Complement Med Ther. 2023;23:340. doi:10.1186/s12906-023-04167-6
- Sovijit WN, Sovijit WE, Pu S, Usuda K, Inoue R, et al. Ovarian progesterone suppresses depression and anxiety-like behaviors by increasing the Lactobacillus population of gut microbiota in ovariectomized mice. Neurosci Res. 2021;168:76. doi:10.1016/j.neures.2019.04.005
- Britton RA, Irwin R, Quach D, Schaefer L, Zhang J, et al. Probiotic L. reuteri treatment prevents bone loss in a menopausal ovariectomized mouse model. J Cell Physiol. 2014;229:1822. doi:10.1002/jcp.24636
