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SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.9
USERS' SCORE
Good
Based on 1 Reviews
8.5
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Turmeric ExtractCurcuma longa (Rhizome)(95% [475 mg] Total Curcuminoids)
500 mg
†
Top Medical Research Studies
9
Curcumin may mitigate menopause effects
Curcumin Supplementation Decreases Intestinal Adiposity Accumulation, Serum Cholesterol Alterations, and Oxidative Stress in Ovariectomized Rats.
Highly relevant to menopause research
We focused on how curcumin, a natural compound found in turmeric, could help address menopause-related challenges, particularly oxidative stress and lipid profile issues. Our study utilized female Wistar rats, dividing them into two main groups: those who underwent ovariectomy (OVX)—a model for menopause—and those that were sham-operated.
We gave the OVX rats either a vehicle or varying doses of curcumin over 30 days and observed significant findings. The OVX rats showed increased intestinal fat and higher levels of harmful substances like IL-6 and LDL cholesterol compared to the sham group, highlighting the negative impact of menopause on health. However, curcumin supplementation appeared to notably reduce these adverse effects, bringing many parameters back to levels similar to those seen in the sham-operated rats.
Our findings suggest that curcumin may serve as a promising option for managing changes in lipid metabolism and reducing oxidative damage that often accompany menopause. This study indicates a potential path for further exploration into natural treatments for menopause-related health issues.
We gave the OVX rats either a vehicle or varying doses of curcumin over 30 days and observed significant findings. The OVX rats showed increased intestinal fat and higher levels of harmful substances like IL-6 and LDL cholesterol compared to the sham group, highlighting the negative impact of menopause on health. However, curcumin supplementation appeared to notably reduce these adverse effects, bringing many parameters back to levels similar to those seen in the sham-operated rats.
Our findings suggest that curcumin may serve as a promising option for managing changes in lipid metabolism and reducing oxidative damage that often accompany menopause. This study indicates a potential path for further exploration into natural treatments for menopause-related health issues.
Read More
9
Curcumin alleviates menopause symptoms
Oral administration of curcumin relieves behavioral alterations and oxidative stress in the frontal cortex, hippocampus, and striatum of ovariectomized Wistar rats.
High relevance to menopause treatment
In our exploration of curcumin's effects on menopause, we conducted a study involving female Wistar rats, some of whom underwent a procedure known as ovariectomy (OVX). This method mimics menopause and allows us to observe physiological changes related to anxiety and oxidative stress. We divided the rats into groups: a sham-operated group and OVX groups, some of which received curcumin supplements while others did not.
Over 30 days, we observed signs of increased anxiety and oxidative stress in the OVX rats. They exhibited reduced locomotor activity and changes in specific brain regions, indicated by markers of oxidative damage. Notably, after administering curcumin, we found a significant reduction in these concerning effects. Curcumin seemed to improve behavioral outcomes and alleviate oxidative stress, almost bringing the OVX rats' conditions in line with those of the sham-operated group.
Our findings suggest that curcumin could serve as a beneficial alternative treatment for anxiety and brain oxidative damage linked to menopause. As we explore natural alternatives to hormone therapies, the potential of curcumin stands out as a promising aid for managing menopause-related challenges.
Over 30 days, we observed signs of increased anxiety and oxidative stress in the OVX rats. They exhibited reduced locomotor activity and changes in specific brain regions, indicated by markers of oxidative damage. Notably, after administering curcumin, we found a significant reduction in these concerning effects. Curcumin seemed to improve behavioral outcomes and alleviate oxidative stress, almost bringing the OVX rats' conditions in line with those of the sham-operated group.
Our findings suggest that curcumin could serve as a beneficial alternative treatment for anxiety and brain oxidative damage linked to menopause. As we explore natural alternatives to hormone therapies, the potential of curcumin stands out as a promising aid for managing menopause-related challenges.
Read More
7
Curcumin improves vascular health
The Role of Curcumin in Modulating Vascular Function and Structure during Menopause: A Systematic Review.
Limited studies; further research needed.
We examined how curcumin, the active ingredient in turmeric, might help improve vascular health in women undergoing menopause. As women transition through menopause, they often experience an increased risk of cardiovascular disease, which is linked to changes in vascular structure and function. This study reviewed several clinical and preclinical studies specifically focusing on the effects of curcumin on blood vessel health during this critical phase.
Through our analysis, we found that curcumin appears to provide several benefits. It may enhance endothelial function, improve arterial compliance, and positively affect hemodynamic parameters—these are all crucial factors for maintaining good cardiovascular health. Furthermore, curcumin showed promise in reducing the formation of atherosclerotic lesions, which can lead to serious heart conditions.
However, it is important to note that while the findings are encouraging, they stem from a limited number of studies. We reviewed seven articles, including three animal studies and four clinical trials. To draw more definitive conclusions, larger clinical trials using rigorous methodologies are necessary.
In summary, curcumin could be a valuable supplement for improving vascular health in menopausal women, but more research is needed to fully understand its effectiveness.
Through our analysis, we found that curcumin appears to provide several benefits. It may enhance endothelial function, improve arterial compliance, and positively affect hemodynamic parameters—these are all crucial factors for maintaining good cardiovascular health. Furthermore, curcumin showed promise in reducing the formation of atherosclerotic lesions, which can lead to serious heart conditions.
However, it is important to note that while the findings are encouraging, they stem from a limited number of studies. We reviewed seven articles, including three animal studies and four clinical trials. To draw more definitive conclusions, larger clinical trials using rigorous methodologies are necessary.
In summary, curcumin could be a valuable supplement for improving vascular health in menopausal women, but more research is needed to fully understand its effectiveness.
Read More
Most Useful Reviews
8.8
Menopause symptom relief
Excellent! Curcumin is a promising ingredient for supporting a healthy inflammatory response. It's proven to have numerous healing properties, including benefits for women during menopause, by reducing symptoms such as PMS and hot flashes. Additionally, turmeric positively affects skin condition by supporting collagen synthesis. I take one capsule daily with meals and highly recommend it!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.9
9
Turmeric aids menopausal health
Combined supplementation with hesperidin, phytosterols and curcumin decreases adiposity and improves metabolic health in ovariectomized rats.
Curcumin effects less clear
We conducted a study to explore the potential benefits of combining turmeric (curcumin) with hesperidin and phytosterols in supporting metabolic health during menopause. Using ovariectomized (OVX) rats, which serve as a model for postmenopausal conditions, we administered a special supplement for 57 days to assess its impact on fat accumulation and metabolic issues linked to menopause.
The results were quite promising. We found that the rats receiving this multi-ingredient supplement experienced significantly reduced fat mass and improved markers of metabolic health. Specifically, they had lower total fat mass, decreased fat deposits in key areas, and reduced levels of leptin, a hormone associated with fat storage. These improvements were comparable to those seen in rats receiving estrogen treatment.
Notably, the supplement also increased lean body mass and improved the ratio of beneficial hormones. This suggests that the combination of curcumin, hesperidin, and phytosterols may be an effective strategy to help manage obesity and enhance cardiovascular health during menopause. Overall, our findings point to exciting possibilities for using this natural blend as an alternative therapy for menopausal women struggling with weight and metabolic challenges.
The results were quite promising. We found that the rats receiving this multi-ingredient supplement experienced significantly reduced fat mass and improved markers of metabolic health. Specifically, they had lower total fat mass, decreased fat deposits in key areas, and reduced levels of leptin, a hormone associated with fat storage. These improvements were comparable to those seen in rats receiving estrogen treatment.
Notably, the supplement also increased lean body mass and improved the ratio of beneficial hormones. This suggests that the combination of curcumin, hesperidin, and phytosterols may be an effective strategy to help manage obesity and enhance cardiovascular health during menopause. Overall, our findings point to exciting possibilities for using this natural blend as an alternative therapy for menopausal women struggling with weight and metabolic challenges.
Read More
9
Turmeric aids menopausal health
Curcuma comosa reduces visceral adipose tissue and improves dyslipidemia in ovariectomized rats.
Relevant effects on menopause explored
We investigated how Curcuma comosa, a plant commonly known as turmeric, impacts menopause by emphasizing its effects on weight and lipid levels. In a controlled study, adult female rats that underwent ovariectomy—a procedure that induces menopause—were treated with either Curcuma comosa extract, a specific phytoestrogen from the plant, or estrogen itself.
Over 12 weeks, we observed that the turmeric treatment not only reduced visceral fat but also improved lipid profiles in these estrogen-deprived rats. Specifically, the treatments helped to lower levels of harmful lipids while promoting beneficial ones. We found that the treatment led to changes in the expression of important proteins linked to fat metabolism, such as AMPK-α and PPAR-α, which play crucial roles in fat synthesis and burning.
Overall, our findings support the potential of Curcuma comosa as a natural aid for managing obesity and poor lipid health in postmenopausal women. Given these results, incorporating this plant into diets might offer a promising way to promote health after menopause.
Over 12 weeks, we observed that the turmeric treatment not only reduced visceral fat but also improved lipid profiles in these estrogen-deprived rats. Specifically, the treatments helped to lower levels of harmful lipids while promoting beneficial ones. We found that the treatment led to changes in the expression of important proteins linked to fat metabolism, such as AMPK-α and PPAR-α, which play crucial roles in fat synthesis and burning.
Overall, our findings support the potential of Curcuma comosa as a natural aid for managing obesity and poor lipid health in postmenopausal women. Given these results, incorporating this plant into diets might offer a promising way to promote health after menopause.
Read More
9
Curcumin alleviates menopause symptoms
Oral administration of curcumin relieves behavioral alterations and oxidative stress in the frontal cortex, hippocampus, and striatum of ovariectomized Wistar rats.
High relevance to menopause treatment
In our exploration of curcumin's effects on menopause, we conducted a study involving female Wistar rats, some of whom underwent a procedure known as ovariectomy (OVX). This method mimics menopause and allows us to observe physiological changes related to anxiety and oxidative stress. We divided the rats into groups: a sham-operated group and OVX groups, some of which received curcumin supplements while others did not.
Over 30 days, we observed signs of increased anxiety and oxidative stress in the OVX rats. They exhibited reduced locomotor activity and changes in specific brain regions, indicated by markers of oxidative damage. Notably, after administering curcumin, we found a significant reduction in these concerning effects. Curcumin seemed to improve behavioral outcomes and alleviate oxidative stress, almost bringing the OVX rats' conditions in line with those of the sham-operated group.
Our findings suggest that curcumin could serve as a beneficial alternative treatment for anxiety and brain oxidative damage linked to menopause. As we explore natural alternatives to hormone therapies, the potential of curcumin stands out as a promising aid for managing menopause-related challenges.
Over 30 days, we observed signs of increased anxiety and oxidative stress in the OVX rats. They exhibited reduced locomotor activity and changes in specific brain regions, indicated by markers of oxidative damage. Notably, after administering curcumin, we found a significant reduction in these concerning effects. Curcumin seemed to improve behavioral outcomes and alleviate oxidative stress, almost bringing the OVX rats' conditions in line with those of the sham-operated group.
Our findings suggest that curcumin could serve as a beneficial alternative treatment for anxiety and brain oxidative damage linked to menopause. As we explore natural alternatives to hormone therapies, the potential of curcumin stands out as a promising aid for managing menopause-related challenges.
Read More
9
Curcumin may mitigate menopause effects
Curcumin Supplementation Decreases Intestinal Adiposity Accumulation, Serum Cholesterol Alterations, and Oxidative Stress in Ovariectomized Rats.
Highly relevant to menopause research
We focused on how curcumin, a natural compound found in turmeric, could help address menopause-related challenges, particularly oxidative stress and lipid profile issues. Our study utilized female Wistar rats, dividing them into two main groups: those who underwent ovariectomy (OVX)—a model for menopause—and those that were sham-operated.
We gave the OVX rats either a vehicle or varying doses of curcumin over 30 days and observed significant findings. The OVX rats showed increased intestinal fat and higher levels of harmful substances like IL-6 and LDL cholesterol compared to the sham group, highlighting the negative impact of menopause on health. However, curcumin supplementation appeared to notably reduce these adverse effects, bringing many parameters back to levels similar to those seen in the sham-operated rats.
Our findings suggest that curcumin may serve as a promising option for managing changes in lipid metabolism and reducing oxidative damage that often accompany menopause. This study indicates a potential path for further exploration into natural treatments for menopause-related health issues.
We gave the OVX rats either a vehicle or varying doses of curcumin over 30 days and observed significant findings. The OVX rats showed increased intestinal fat and higher levels of harmful substances like IL-6 and LDL cholesterol compared to the sham group, highlighting the negative impact of menopause on health. However, curcumin supplementation appeared to notably reduce these adverse effects, bringing many parameters back to levels similar to those seen in the sham-operated rats.
Our findings suggest that curcumin may serve as a promising option for managing changes in lipid metabolism and reducing oxidative damage that often accompany menopause. This study indicates a potential path for further exploration into natural treatments for menopause-related health issues.
Read More
9
Tumeric compound boosts bone health
A diarylheptanoid phytoestrogen from Curcuma comosa, 1,7-diphenyl-4,6-heptadien-3-ol, accelerates human osteoblast proliferation and differentiation.
Moderate relevance to menopause effects
We examined how a specific compound from turmeric, called diarylheptanoid or DPHD, impacts bone health during menopause. Previous research indicated that turmeric could potentially relieve menopausal symptoms, but we wanted to focus on how DPHD affects osteoblasts, the cells that help form bone.
In our study, we found that DPHD significantly increased the proliferation and differentiation of human osteoblasts at low concentrations. This means that DPHD helps these bone cells grow and become more active, which is essential for maintaining bone density, especially in menopausal women.
Furthermore, we discovered that the effects of DPHD were comparable to those of 17β-estradiol, a well-known estrogen hormone. The compound not only elevated certain vital bone markers but also improved the balance of protective factors in bone metabolism.
Importantly, these benefits were negated when an estrogen receptor blocker was introduced, which highlights the importance of estrogen-related pathways in this process. We believe that DPHD holds promise as a natural alternative to support bone health for menopausal individuals.
In our study, we found that DPHD significantly increased the proliferation and differentiation of human osteoblasts at low concentrations. This means that DPHD helps these bone cells grow and become more active, which is essential for maintaining bone density, especially in menopausal women.
Furthermore, we discovered that the effects of DPHD were comparable to those of 17β-estradiol, a well-known estrogen hormone. The compound not only elevated certain vital bone markers but also improved the balance of protective factors in bone metabolism.
Importantly, these benefits were negated when an estrogen receptor blocker was introduced, which highlights the importance of estrogen-related pathways in this process. We believe that DPHD holds promise as a natural alternative to support bone health for menopausal individuals.
Read More
User Reviews
USERS' SCORE
Good
Based on 1 Reviews
8.5
8.8
Menopause symptom relief
Excellent! Curcumin is a promising ingredient for supporting a healthy inflammatory response. It's proven to have numerous healing properties, including benefits for women during menopause, by reducing symptoms such as PMS and hot flashes. Additionally, turmeric positively affects skin condition by supporting collagen synthesis. I take one capsule daily with meals and highly recommend it!
Read More
