Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 20 Researches
7.7
USERS' SCORE
Moderately Good
Based on 9 Reviews
7.9
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
Vitamin B6 (as Pyridoxal-5-Phosphate)
1.5 mg
88%
Folate (400 mcg as (6S)-5-MTHF [from (6S)-5-Methyltetrahydrofolate Glucosamine Salt])
680 mcg DFE‡
170%
Vitamin B12 (as Methylcobalamin)
1,000 mcg
41,667%
Top Medical Research Studies
9
We explored how Myo-inositol (MI) might help manage diabetes by studying its effects in db/db mice, a common model for type 2 diabetes. Findings showed that MI reduced high blood sugar and insulin levels, and it even improved insulin resistance, much like metformin does.
Additionally, MI lowered high triglyceride and cholesterol levels, which can benefit overall heart health. Interestingly, while it reduced fat cell formation, it didn't help control obesity in these mice. Overall, MI shows promise as a supportive treatment for hyperglycemia and related issues in diabetes patients.
Additionally, MI lowered high triglyceride and cholesterol levels, which can benefit overall heart health. Interestingly, while it reduced fat cell formation, it didn't help control obesity in these mice. Overall, MI shows promise as a supportive treatment for hyperglycemia and related issues in diabetes patients.
Read More
7
Annona muricata aids diabetes treatment
We explored the antidiabetic properties of Annona muricata leaf extract using a metabolomics approach on diabetes-induced rats. The study involved administering two doses of the extract to evaluate its impacts on metabolic profiles over four weeks.
Remarkably, the lower dose showed significant benefits, lowering serum urea levels while exhibiting effects similar to metformin. We found that the extract positively influenced various metabolic pathways, confirming its traditional use for managing diabetes. Overall, the research highlights promising insights into how this natural treatment could aid in diabetes management.
Remarkably, the lower dose showed significant benefits, lowering serum urea levels while exhibiting effects similar to metformin. We found that the extract positively influenced various metabolic pathways, confirming its traditional use for managing diabetes. Overall, the research highlights promising insights into how this natural treatment could aid in diabetes management.
Read More
7
We explored the connection between folate metabolites and diabetic kidney disease (DKD), a serious complication that affects around 40% of individuals with type 2 diabetes. Our investigation drew on data from a large U.S. survey spanning nearly a decade, from 2011 to 2020, focusing on various forms of folate to see how they relate to DKD.
Through our research, we discovered that higher levels of total folate and 5-Methyl-THF were associated with a lower risk of DKD. Specifically, those in the highest quintile of these folate forms had an odds ratio (OR) of 0.73, indicating a protective effect. In contrast, certain other forms of folate, like RBC folate and UMFA, were linked to an increased risk of DKD, with ORs exceeding 1.4. This suggests that not all folate is beneficial when it comes to this condition.
Overall, our findings highlight the potential importance of promoting 5-Methyl-THF while minimizing UMFA for better diabetes management. It's clear that a balanced approach to folate intake could be crucial for maintaining kidney health in those with diabetes.
Through our research, we discovered that higher levels of total folate and 5-Methyl-THF were associated with a lower risk of DKD. Specifically, those in the highest quintile of these folate forms had an odds ratio (OR) of 0.73, indicating a protective effect. In contrast, certain other forms of folate, like RBC folate and UMFA, were linked to an increased risk of DKD, with ORs exceeding 1.4. This suggests that not all folate is beneficial when it comes to this condition.
Overall, our findings highlight the potential importance of promoting 5-Methyl-THF while minimizing UMFA for better diabetes management. It's clear that a balanced approach to folate intake could be crucial for maintaining kidney health in those with diabetes.
Read More
Most Useful Reviews
7.5
Improved blood counts
26 people found this helpful
My husband has type 2 diabetes. He takes Glucofazhlong 1000 regularly, which has decreased his vitamin B12 and folic acid levels. He uses this product once daily under the tongue for three months with two-month intervals. His blood counts have improved, and his homocysteine levels have decreased. Additionally, he takes Q10, necessary for those with metabolic syndrome due to diabetes. I highly recommend it!
Read More
9
Positive results expected
I purchased these vitamins due to my diabetes mellitus, as my doctor advised taking B vitamins every six months. These vitamins are well-formulated for absorption, featuring B12-methylcobalamin, B6-P-5-P, and folic acid in folate form. The composition is excellent. I have begun taking them, and the flavour is pleasant, reminiscent of lemon sweets. They are easy to tolerate, and I believe that after completing the entire pack, I will see positive results.
Read More
7.5
Helps with depression
This product has adequate doses of all actives; I find that the 1.5mg of vitamin B6 here does not cause me insomnia, unlike doses above 5mg. It significantly aids those with depression and diabetes, especially as metformin may lower B12 levels and depression can be exacerbated by low B12 and folate.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 20 Researches
7.7
- All Researches
9
Thiamine treatment aids diabetes management
We examined a rare condition known as thiamine-responsive megaloblastic anaemia (TRMA) in a young man with type 1 diabetes and unexplained pancytopenia. After thorough testing revealed genetic factors, we found that daily thiamine supplementation effectively resolved his anemia.
More importantly, this treatment not only improved his blood counts but also lowered his insulin needs. This highlights the significance of identifying genetic causes in young patients presenting with such symptoms.
More importantly, this treatment not only improved his blood counts but also lowered his insulin needs. This highlights the significance of identifying genetic causes in young patients presenting with such symptoms.
Read More
9
We explored how Myo-inositol (MI) might help manage diabetes by studying its effects in db/db mice, a common model for type 2 diabetes. Findings showed that MI reduced high blood sugar and insulin levels, and it even improved insulin resistance, much like metformin does.
Additionally, MI lowered high triglyceride and cholesterol levels, which can benefit overall heart health. Interestingly, while it reduced fat cell formation, it didn't help control obesity in these mice. Overall, MI shows promise as a supportive treatment for hyperglycemia and related issues in diabetes patients.
Additionally, MI lowered high triglyceride and cholesterol levels, which can benefit overall heart health. Interestingly, while it reduced fat cell formation, it didn't help control obesity in these mice. Overall, MI shows promise as a supportive treatment for hyperglycemia and related issues in diabetes patients.
Read More
9
We evaluated the impact of 5-methyltetrahydrofolate (5-MTHF) and an aqueous extract on diabetes by examining their effects in a rat model with induced diabetes. Our findings were based on a combination of in silico docking studies and in vitro assays, which indicated that folates bind effectively with proteins that regulate glucose metabolism.
In our tests, we observed that 5-MTHF demonstrated stronger inhibitory action on alpha-amylase than folic acid, indicating its potential for managing blood sugar levels. When we administered 5-MTHF and the aqueous extract to diabetic Wistar rats, both supplements contributed to significant reductions in fasting blood glucose and improvements in glucose tolerance.
Furthermore, alongside controlling blood sugar, we noted that supplementation helped reduce obesity, address hyperlipidemia, and enhance antioxidant enzyme levels. Remarkably, the higher dosage of 5-MTHF provided better results than the aqueous extract and higher doses of folic acid, suggesting its effectiveness as a treatment option. By incorporating the aqueous extract, we also found an increase in serum folate levels, indicating its role as a folate source enriched with other beneficial phytochemicals.
Overall, we highlighted the promising effects of both the aqueous extract and 5-MTHF, emphasizing their potential as dietary supplements for diabetes management and its associated complications.
In our tests, we observed that 5-MTHF demonstrated stronger inhibitory action on alpha-amylase than folic acid, indicating its potential for managing blood sugar levels. When we administered 5-MTHF and the aqueous extract to diabetic Wistar rats, both supplements contributed to significant reductions in fasting blood glucose and improvements in glucose tolerance.
Furthermore, alongside controlling blood sugar, we noted that supplementation helped reduce obesity, address hyperlipidemia, and enhance antioxidant enzyme levels. Remarkably, the higher dosage of 5-MTHF provided better results than the aqueous extract and higher doses of folic acid, suggesting its effectiveness as a treatment option. By incorporating the aqueous extract, we also found an increase in serum folate levels, indicating its role as a folate source enriched with other beneficial phytochemicals.
Overall, we highlighted the promising effects of both the aqueous extract and 5-MTHF, emphasizing their potential as dietary supplements for diabetes management and its associated complications.
Read More
9
We explored the potential connection between red blood cell (RBC) folate levels and diabetic nephropathy (DN) in individuals with type 2 diabetes mellitus. Using data from the National Health and Nutrition Examination Survey (NHANES) spanning from 2011 to 2018, we carried out a cross-sectional analysis involving 3,070 adults diagnosed with type 2 diabetes.
Our findings reveal a noteworthy positive relationship between RBC folate levels and the risk of developing diabetic nephropathy. Specifically, even after adjusting for various influencing factors, our analysis indicated that higher levels of RBC folate were linked to an increased risk of DN, with a significant odds ratio of 1.38. This suggests that as RBC folate levels rise, so does the likelihood of experiencing complications related to kidney function in diabetes.
Furthermore, our subgroup analysis supported these findings, showing consistent patterns across different groups. The curve fitting we conducted also pointed to a linear relationship between RBC folate and diabetic nephropathy, indicating that higher folate concentrations in the blood are indeed associated with heightened risk.
Overall, our study suggests that RBC folate might serve as an important indicator of folate status and its implications for kidney health in those with type 2 diabetes. As we delve deeper into the implications of these findings, it becomes clear that folate levels deserve consideration in the broader context of diabetes management.
Our findings reveal a noteworthy positive relationship between RBC folate levels and the risk of developing diabetic nephropathy. Specifically, even after adjusting for various influencing factors, our analysis indicated that higher levels of RBC folate were linked to an increased risk of DN, with a significant odds ratio of 1.38. This suggests that as RBC folate levels rise, so does the likelihood of experiencing complications related to kidney function in diabetes.
Furthermore, our subgroup analysis supported these findings, showing consistent patterns across different groups. The curve fitting we conducted also pointed to a linear relationship between RBC folate and diabetic nephropathy, indicating that higher folate concentrations in the blood are indeed associated with heightened risk.
Overall, our study suggests that RBC folate might serve as an important indicator of folate status and its implications for kidney health in those with type 2 diabetes. As we delve deeper into the implications of these findings, it becomes clear that folate levels deserve consideration in the broader context of diabetes management.
Read More
9
We explored the effectiveness of vitamin B12 in treating diabetic ocular nerve palsy, a complication that can occur in people with diabetes. In a recent study, fifty individuals with this condition were divided into two groups. One group received steroid treatments while the other was treated with vitamin B12 injections.
After assessing ocular movements at three points during treatment, we observed a notable improvement in those receiving vitamin B12 compared to those receiving steroids. Specifically, the vitamin B12 group showed an enhancement of eye movements by an average of 1.04, while the steroid group had a lesser improvement of 0.75. This difference was statistically significant, suggesting that vitamin B12 may be more effective in aiding recovery of eye movement in these patients.
Importantly, treating diabetic neuropathy with vitamin supplementation not only addresses possible nutritional deficiencies but could also improve overall quality of life for patients. This study highlights the potential benefits of vitamin B12 therapy, making it an appealing option for individuals dealing with the effects of diabetic-related nerve issues.
After assessing ocular movements at three points during treatment, we observed a notable improvement in those receiving vitamin B12 compared to those receiving steroids. Specifically, the vitamin B12 group showed an enhancement of eye movements by an average of 1.04, while the steroid group had a lesser improvement of 0.75. This difference was statistically significant, suggesting that vitamin B12 may be more effective in aiding recovery of eye movement in these patients.
Importantly, treating diabetic neuropathy with vitamin supplementation not only addresses possible nutritional deficiencies but could also improve overall quality of life for patients. This study highlights the potential benefits of vitamin B12 therapy, making it an appealing option for individuals dealing with the effects of diabetic-related nerve issues.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 9 Reviews
7.9
- All Reviews
- Positive Reviews
- Negative Reviews
7.5
Improved blood counts
26 people found this helpful
My husband has type 2 diabetes. He takes Glucofazhlong 1000 regularly, which has decreased his vitamin B12 and folic acid levels. He uses this product once daily under the tongue for three months with two-month intervals. His blood counts have improved, and his homocysteine levels have decreased. Additionally, he takes Q10, necessary for those with metabolic syndrome due to diabetes. I highly recommend it!
Read More
9
Positive results expected
I purchased these vitamins due to my diabetes mellitus, as my doctor advised taking B vitamins every six months. These vitamins are well-formulated for absorption, featuring B12-methylcobalamin, B6-P-5-P, and folic acid in folate form. The composition is excellent. I have begun taking them, and the flavour is pleasant, reminiscent of lemon sweets. They are easy to tolerate, and I believe that after completing the entire pack, I will see positive results.
Read More
7.5
Helps with depression
This product has adequate doses of all actives; I find that the 1.5mg of vitamin B6 here does not cause me insomnia, unlike doses above 5mg. It significantly aids those with depression and diabetes, especially as metformin may lower B12 levels and depression can be exacerbated by low B12 and folate.
Read More
7.5
Convenient B12 source
These work brilliantly; with type 2 diabetes, my B12 levels decrease, and this form effectively replenishes my deficiencies. The product is easy to take.
Read More
6
Convenient for forgetful
6 people found this helpful
For those who tend to forget, this product is excellent for type 2 diabetes. I often forget to take B12 and folic acid, so having both in one is handy. However, B12 is better absorbed when the tablet dissolves. Generally, I recommend it.
Read More
Frequently Asked Questions
7.5
Improved blood counts
26 people found this helpful
My husband has type 2 diabetes. He takes Glucofazhlong 1000 regularly, which has decreased his vitamin B12 and folic acid levels. He uses this product once daily under the tongue for three months with two-month intervals. His blood counts have improved, and his homocysteine levels have decreased. Additionally, he takes Q10, necessary for those with metabolic syndrome due to diabetes. I highly recommend it!
9
Positive results expected
I purchased these vitamins due to my diabetes mellitus, as my doctor advised taking B vitamins every six months. These vitamins are well-formulated for absorption, featuring B12-methylcobalamin, B6-P-5-P, and folic acid in folate form. The composition is excellent. I have begun taking them, and the flavour is pleasant, reminiscent of lemon sweets. They are easy to tolerate, and I believe that after completing the entire pack, I will see positive results.
6
Effective for nerves
An effective product for boosting B12 levels and protecting nerves in individuals with diabetes.
7.5
Helps with depression
This product has adequate doses of all actives; I find that the 1.5mg of vitamin B6 here does not cause me insomnia, unlike doses above 5mg. It significantly aids those with depression and diabetes, especially as metformin may lower B12 levels and depression can be exacerbated by low B12 and folate.
6
Convenient for forgetful
6 people found this helpful
For those who tend to forget, this product is excellent for type 2 diabetes. I often forget to take B12 and folic acid, so having both in one is handy. However, B12 is better absorbed when the tablet dissolves. Generally, I recommend it.
7.5
Convenient B12 source
These work brilliantly; with type 2 diabetes, my B12 levels decrease, and this form effectively replenishes my deficiencies. The product is easy to take.
6
Accessible vitamin B12
As I take medication for type 2 diabetes, I've experienced a lack of vitamin B12 in my body. This product combines B12 with folic acid in a convenient form, plus it tastes pleasant.
7
Annona muricata aids diabetes treatment
We explored the antidiabetic properties of Annona muricata leaf extract using a metabolomics approach on diabetes-induced rats. The study involved administering two doses of the extract to evaluate its impacts on metabolic profiles over four weeks.
Remarkably, the lower dose showed significant benefits, lowering serum urea levels while exhibiting effects similar to metformin. We found that the extract positively influenced various metabolic pathways, confirming its traditional use for managing diabetes. Overall, the research highlights promising insights into how this natural treatment could aid in diabetes management.
Remarkably, the lower dose showed significant benefits, lowering serum urea levels while exhibiting effects similar to metformin. We found that the extract positively influenced various metabolic pathways, confirming its traditional use for managing diabetes. Overall, the research highlights promising insights into how this natural treatment could aid in diabetes management.
8
We explored how nicotinamide riboside (NR), a vitamin precursor to NAD, influences bone loss in type 2 diabetic mice. By administering NR to mice with diabetes induced by a high-fat diet and streptozotocin, we observed impressive results.
NR not only improved insulin resistance, but also enhanced bone quality and microarchitecture. Plus, it helped reduce bone resorption and positively influenced crucial signaling pathways related to bone health.
Overall, our findings suggest that NR has potential as a treatment for diabetes-related bone issues, but further studies are needed to solidify these results.
NR not only improved insulin resistance, but also enhanced bone quality and microarchitecture. Plus, it helped reduce bone resorption and positively influenced crucial signaling pathways related to bone health.
Overall, our findings suggest that NR has potential as a treatment for diabetes-related bone issues, but further studies are needed to solidify these results.
7
We reviewed data from a 2009-2010 survey to understand how vitamin B6 influences the link between type 2 diabetes and periodontitis, a serious gum disease.
Our findings revealed that individuals with diabetes have an increased risk of periodontitis. Importantly, higher levels of vitamin B6 appeared to reduce this risk.
This suggests that maintaining adequate vitamin B6 intake may benefit those with diabetes by potentially lowering their chances of developing gum disease.
Our findings revealed that individuals with diabetes have an increased risk of periodontitis. Importantly, higher levels of vitamin B6 appeared to reduce this risk.
This suggests that maintaining adequate vitamin B6 intake may benefit those with diabetes by potentially lowering their chances of developing gum disease.
8
We examined the impact of folate, a water-soluble vitamin, on glycemic control and insulin resistance in individuals with type 2 diabetes. By systematically reviewing various studies, we uncovered that supplementing with folic acid could enhance insulin sensitivity.
Our analysis included a range of systematic reviews and meta-analyses focusing on the effects of different water-soluble vitamins, like B-1, B-3, biotin, B-9 (folate), and vitamin C. The findings highlighted that vitamin C also shows positive outcomes in managing blood sugar levels, but we observed that folic acid stood out in its ability to combat insulin resistance effectively.
Overall, while folic acid supplementation appears promising, we emphasized the need for further high-quality randomized controlled trials. This will help solidify our understanding and ensure that we can rely on folate as an effective treatment option for diabetes management.
Our analysis included a range of systematic reviews and meta-analyses focusing on the effects of different water-soluble vitamins, like B-1, B-3, biotin, B-9 (folate), and vitamin C. The findings highlighted that vitamin C also shows positive outcomes in managing blood sugar levels, but we observed that folic acid stood out in its ability to combat insulin resistance effectively.
Overall, while folic acid supplementation appears promising, we emphasized the need for further high-quality randomized controlled trials. This will help solidify our understanding and ensure that we can rely on folate as an effective treatment option for diabetes management.
9
We explored how Myo-inositol (MI) might help manage diabetes by studying its effects in db/db mice, a common model for type 2 diabetes. Findings showed that MI reduced high blood sugar and insulin levels, and it even improved insulin resistance, much like metformin does.
Additionally, MI lowered high triglyceride and cholesterol levels, which can benefit overall heart health. Interestingly, while it reduced fat cell formation, it didn't help control obesity in these mice. Overall, MI shows promise as a supportive treatment for hyperglycemia and related issues in diabetes patients.
Additionally, MI lowered high triglyceride and cholesterol levels, which can benefit overall heart health. Interestingly, while it reduced fat cell formation, it didn't help control obesity in these mice. Overall, MI shows promise as a supportive treatment for hyperglycemia and related issues in diabetes patients.
References
- Zubaidi SN, Wong PL, Qadi WSM, Dawoud EAD, Hamezah HS, et al. Deciphering the mechanism of Annona muricata leaf extract in alloxan-nicotinamide-induced diabetic rat model with H-NMR-based metabolomics approach. J Pharm Biomed Anal. 2025;260:116806. doi:10.1016/j.jpba.2025.116806
- Zhu J, Xu W, Wu S, Song D. Vitamin B6 status, type 2 diabetes mellitus, and periodontitis: evidence from the NHANES database 2009-2010. BMC Oral Health. 2025;25:299. doi:10.1186/s12903-025-05597-z
- Gao J, Meng X, Yang X, Xie C, Tian C, et al. The protection of nicotinamide riboside against diabetes mellitus-induced bone loss via OXPHOS. Bone. 2025;193:117411. doi:10.1016/j.bone.2025.117411
- Lee D, Kim SJ, Choi YJ, Rho YH, Kang TS, et al. The Glucose-Lowering Effect of and D-Pinitol: Studies on Insulin Secretion in INS-1 Cells and the Reduction of Blood Glucose in Diabetic Rats. Nutrients. 2025;17. doi:10.3390/nu17010193
- Brossfield AV, McMahon DJ, Fernando J, Omeragic B, Majeed R, et al. The Effects of the AGE Inhibitor Pyridoxamine on Bone in Older Women With Type 2 Diabetes: A Randomized Clinical Trial. J Clin Endocrinol Metab. 2025;110:961. doi:10.1210/clinem/dgae700
- Pascoe MA, Hall AM, Gray A. Thiamine-responsive megaloblastic anaemia in a young adult with acute pancytopenia. BMJ Case Rep. 2024;17. doi:10.1136/bcr-2024-261435
- Didangelos T, Karlafti E, Kotzakioulafi E, Giannoulaki P, Kontoninas Z, et al. Efficacy and Safety of the Combination of Palmitoylethanolamide, Superoxide Dismutase, Alpha Lipoic Acid, Vitamins B12, B1, B6, E, Mg, Zn and Nicotinamide for 6 Months in People with Diabetic Neuropathy. Nutrients. 2024;16. doi:10.3390/nu16183045
- D'Haese S, Claes L, Jaeken E, Deluyker D, Evens L, et al. Pyridoxamine Alleviates Cardiac Fibrosis and Oxidative Stress in Western Diet-Induced Prediabetic Rats. Int J Mol Sci. 2024;25. doi:10.3390/ijms25158508
- Rad MG, Sharifi M, Meamar R, Soltani N. Long term administration of thiamine disulfide improves FOXO1/PEPCK pathway in liver to reduce insulin resistance in type 1 diabetes rat model. Biomed Pharmacother. 2024;177:117053. doi:10.1016/j.biopha.2024.117053
- Zhu Y, Ying T, Xu M, Chen Q, Wu M, et al. Joint B Vitamin Intake and Type 2 Diabetes Risk: The Mediating Role of Inflammation in a Prospective Shanghai Cohort. Nutrients. 2024;16. doi:10.3390/nu16121901
- Long L, Huang Q, Song T, Dai Z. Myo-inositol rescued insulin resistance and dyslipidemia in db/db mice. J Appl Biomed. 2024;22:74. doi:10.32725/jab.2024.009
- Chai Y, Chen C, Yin X, Wang X, Yu W, et al. Effects of water-soluble vitamins on glycemic control and insulin resistance in adult type 2 diabetes: an umbrella review of meta-analyses. Asia Pac J Clin Nutr. 2025;34:118. doi:10.6133/apjcn.202502_34(1).0012
- Chen L, Liu R, He X, Fang J, Zhou L, et al. Synergistically effects of n-3 PUFA and B vitamins prevent diabetic cognitive dysfunction through promoting TET2-mediated active DNA demethylation. Clin Nutr. 2025;45:111. doi:10.1016/j.clnu.2025.01.002
- Pathikkal A, Bhaskar TK, Prasanthan A, Haritha PK, Puthusseri B, et al. 5-Methyltetrahydrofolate and aqueous extract of () ameliorate diabetes and associated complications in STZ-induced diabetic rats. 3 Biotech. 2025;15:15. doi:10.1007/s13205-024-04170-9
- Liang Y, Ding L, Tao M, Zhu Y. The association of metabolic profile of folate with diabetic kidney disease: evidence from 2011-2020 cycles of the NHANES. Ren Fail. 2024;46:2420830. doi:10.1080/0886022X.2024.2420830
- Yu P, Ji Y, Wang H, Liu K. Association between RBC folate and diabetic nephropathy in Type2 diabetes mellitus patients: a cross-sectional study. Sci Rep. 2024;14:24692. doi:10.1038/s41598-024-76456-0
- N I, Shyam Kumar S. The Effectiveness of Steroid Versus Vitamin Therapy in the Improvement of Extraocular Movements in Patients With Diabetic Cranial Nerve Palsy: A Comparative Study. Cureus. 2024;16:e75656. doi:10.7759/cureus.75656
- Abu-Zahab ZA, Qureshi H, Adham GM, Elzefzafy WM, Zalam SS, et al. Frequency of comorbid diseases with high serum Vitamin B12 levels in patients attending King Salman Medical City (KSAMC), at Madinah. Int J Health Sci (Qassim). 2025;19:15.
- Zhao X, An X, Cui Y, Dong L, Fang Z, et al. TangBi Formula for Painful Diabetic Distal Symmetric Polyneuropathy: A Multicenter, Randomized, Double-Blind, Placebo-Controlled and Parallel-Group Trial. J Diabetes. 2025;17:e70045. doi:10.1111/1753-0407.70045
- Asghar S, Tanvir H, Riaz A, Ejaz MH, Akram M, et al. Prevalence of Vitamin B12 Deficiency in Patients With Type 2 Diabetes Mellitus on Metformin Therapy: A Cross-Sectional Study. Cureus. 2024;16:e72184. doi:10.7759/cureus.72184
