We explored how zinc affects acne through a systematic review and meta-analysis that looked at two main questions. First, we wanted to know if there are differences in zinc levels between people with acne and those without. Second, we examined how effective zinc treatments are for managing acne.
Our findings showed that individuals with acne had noticeably lower serum zinc levels compared to those in the control group. Furthermore, when we looked at treatments, those who received zinc showed a significant reduction in their inflammatory papule count—a common symptom of acne. Importantly, we noted that side effects from zinc supplementation were similar to those seen in other treatments, suggesting that zinc is safe to use.
Overall, acne patients appear to benefit from improved zinc levels, especially when zinc is used either on its own or alongside other acne treatments. This gives hope for those looking for effective ways to tackle acne issues!
Read More
9
Zinc shows promise against acne
An Open-label Study Comparing Oral Zinc to Lymecycline in the Treatment of Acne Vulgaris.
We aimed to explore how effective zinc sulphate is in treating mild to moderate acne compared to the well-known antibiotic lymecycline. In our study, we involved 100 participants who were randomly assigned to receive either zinc sulphate or lymecycline.
To measure the effectiveness of the treatments, we used the Global Acne Grading System and a special questionnaire focused on acne's impact on quality of life. After four and twelve weeks of treatment, we found that both treatments significantly reduced acne severity.
However, the results showed something interesting. The patients who took zinc sulphate reported greater improvements in their quality of life than those on lymecycline. This indicates that zinc not only helps with acne but may also lead to a better overall experience during treatment.
Our findings suggest that zinc sulphate could be a compelling alternative to lymecycline, providing similar clinical benefits without the risk of antibiotic resistance associated with long-term antibiotic use.
Read More
9
Zinc compounds as acne treatment
Zinc(II) Complexes of Amino Acids as New Active Ingredients for Anti-Acne Dermatological Preparations.
We examined the potential of zinc compounds, particularly zinc-amino acid complexes, to effectively treat acne. This study focused on how these zinc formulations could not only help with acne but also ensure safety for the skin.
Initially, we checked the cytotoxicity of the zinc complexes on human skin cells, demonstrating their safety. We then evaluated their antibacterial properties, which are crucial for combating acne-causing bacteria. After finding promising results, we selected zinc complexes with glycine and histidine to create unique gel formulations.
The next steps involved thorough testing of these gel preparations for stability, purity, and tolerability. We confirmed that they maintained their quality over time, showed no irritation or allergic reactions in a patch test with 25 volunteers, and exhibited high microbiological purity.
Ultimately, our findings suggest that these zinc-based gels can be a valuable topical option for acne treatment due to their strong antibacterial performance and minimal toxicity to skin cells. Our dermatological formulations appear safe and effective, contributing positively to acne management.
Read More
Most Useful Reviews
9
Effective for acne
165 people found this helpful
This unique supplement that includes copper has helped improve my skin seboregulation and cleared up my acne. I take one capsule every other day with meals and have experienced no side effects. Highly recommend!
Read More
9
Skin hydration improved
53 people found this helpful
As a fashion model, my skin health is crucial. After suffering from Lyme disease, I switched to alternative therapies including this lactoferrin and colostrum. The results have been outstanding; I have more energy and less joint pain. Additionally, my skin looks more hydrated and is even clearing up acne, making me very pleased with the results!
Read More
9
Hormonal acne relief
34 people found this helpful
I've consulted many doctors who all recommend this product. It contains the ideal doses for women and helped reduce my hormonal acne significantly.
We investigated the effectiveness of a novel microneedle patch designed for acne treatment, which incorporates zinc-based nanoparticles. This patch combines sodium hyaluronate with zinc porphyrin-based metal-organic frameworks and zinc oxide. By using ultrasound to release activated oxygen, we observed a remarkable antibacterial efficiency, achieving a 99.73% reduction in acne-causing bacteria within just 15 minutes.
Zinc plays a crucial role in this innovative approach. Not only does it help eliminate harmful bacteria, but it also appears to enhance skin health. The presence of zinc ions promotes the up-regulation of genes associated with DNA replication, which supports the growth of fibroblasts. This is a vital process for skin repair and rejuvenation, showing that zinc can potentially contribute to both the treatment and recovery of acne-affected skin.
Overall, our findings suggest that this microneedle patch, which utilizes zinc and ultrasound-responsive technology, represents a promising strategy for effectively managing acne without relying on traditional antibiotics.
We investigated how zinc treatment affects acne, particularly focusing on its potential benefits for those suffering from acne rosacea. The study observed that zinc sulfate solution at a concentration of 5% played a notable role in reducing the severity of acne rosacea symptoms.
Findings indicated that around 40% to 60% of patients experienced a moderate to good response after using zinc. This suggests that zinc could be helpful for individuals looking for alternatives or supplements in their acne treatment regimen.
However, it's important to acknowledge that while zinc showed positive results, the isolated effect of zinc alone cannot be fully determined. It might have worked in conjunction with other treatment factors, which complicates our understanding of its effectiveness.
Therefore, we emphasize the need for further studies to clarify exactly how zinc contributes to acne treatment outcomes and to evaluate its role alongside other therapies.
Read More
9
Zinc oxide nanoparticles combat acne
Development and Evaluation of Topical Zinc Oxide Nanogels Formulation Using and Its Effect on Acne Vulgaris.
We assessed the potential of zinc oxide nanoparticles in combating acne. Using biogenically synthesized zinc oxide, we mixed it with a polymer to create a topical nanogel aimed at treating acne. Through rigorous testing against acne-causing bacteria, we observed that these biogenic nanoparticles showed a promising antibacterial effect, particularly against Gram-positive bacteria.
Notably, the particle size of our biogenic zinc oxide nanoparticles measured around 20 nm, indicating a high degree of purity. When pitted against chemogenic counterparts, the biogenic version proved to be more effective. This suggests that zinc oxide, especially when produced biogenically, could be a valuable addition to skincare products targeting acne.
Moreover, the study highlights the environment-friendly aspect of using biogenic zinc oxide in skincare formulations, making it a preferable choice for those concerned about sustainability. Our findings suggest that these hybrid nanogels could serve as an effective solution against skin infections associated with acne, adding to their appeal in modern skincare.
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9
Zinc gel shows promise for acne
Assessment of the Benefit of a Deep Cleansing Gel Containing Salicylic Acid 2%, Zinc Gluconate 0.2% and Lipohydroxy Acids 0.05% in Patients with Mild to Moderate Truncal Acne: Results from an Exploratory Study.
We wanted to find out how effective a cleansing gel containing salicylic acid, zinc gluconate, and lipohydroxy acids is for treating truncal acne. Conducted over 84 days, our study included 51 individuals with mild to moderate acne, and we tracked various skin conditions like the number of acne lesions and the overall skin barrier health.
After regular use of the gel, we observed a significant reduction in total acne lesions—over half were improved by the end of the study. While non-inflammatory lesions saw a drop of 64% and inflammatory lesions were reduced by nearly 30%, the key point is that zinc gluconate was part of a trio of ingredients, making it challenging to pinpoint its specific contribution.
When we considered skin barrier function, a notable improvement was also measured—21.26% better at Day 84. Patients reported no significant side effects or intolerances, suggesting that the ingredients within the gel, including zinc, were well tolerated.
Overall, the evidence hints at zinc's potential benefits as part of a combination treatment against acne. But since it was used together with other active ingredients, we can't solely credit zinc for the results observed.
Read More
9
Zinc shows promise against acne
An Open-label Study Comparing Oral Zinc to Lymecycline in the Treatment of Acne Vulgaris.
We aimed to explore how effective zinc sulphate is in treating mild to moderate acne compared to the well-known antibiotic lymecycline. In our study, we involved 100 participants who were randomly assigned to receive either zinc sulphate or lymecycline.
To measure the effectiveness of the treatments, we used the Global Acne Grading System and a special questionnaire focused on acne's impact on quality of life. After four and twelve weeks of treatment, we found that both treatments significantly reduced acne severity.
However, the results showed something interesting. The patients who took zinc sulphate reported greater improvements in their quality of life than those on lymecycline. This indicates that zinc not only helps with acne but may also lead to a better overall experience during treatment.
Our findings suggest that zinc sulphate could be a compelling alternative to lymecycline, providing similar clinical benefits without the risk of antibiotic resistance associated with long-term antibiotic use.
This unique supplement that includes copper has helped improve my skin seboregulation and cleared up my acne. I take one capsule every other day with meals and have experienced no side effects. Highly recommend!
Read More
9
Skin hydration improved
53 people found this helpful
As a fashion model, my skin health is crucial. After suffering from Lyme disease, I switched to alternative therapies including this lactoferrin and colostrum. The results have been outstanding; I have more energy and less joint pain. Additionally, my skin looks more hydrated and is even clearing up acne, making me very pleased with the results!
Read More
9
Hormonal acne relief
34 people found this helpful
I've consulted many doctors who all recommend this product. It contains the ideal doses for women and helped reduce my hormonal acne significantly.
Read More
9
Helps acne reduction
4 people found this helpful
This supplement really helps reduce my acne. When I do have a breakout, it clears up much quicker than before. Avoid taking it on an empty stomach to prevent nausea.
Read More
9
Prevents acne
3 people found this helpful
Despite a slightly metallic taste, these capsules are small and have worked very well for me. I have tried four different brands, and this is by far the best for preventing acne and inflammation.
Acne is a common skin condition that affects people of all ages, though it's especially prevalent among teenagers and young adults. It occurs when hair follicles become clogged with oil and dead skin cells, leading to the formation of pimples, blackheads, and cysts. The main factors contributing to acne include excess oil production, hormonal changes, and the presence of bacteria on the skin. Acne can manifest in various forms, from mild cases with just a few breakouts to more severe forms that can cause significant inflammation and scarring.
Treatment for acne varies depending on its severity and can range from over-the-counter topical treatments like benzoyl peroxide and salicylic acid to prescription medications including retinoids and antibiotics. Lifestyle adjustments, such as maintaining a balanced diet and proper skin hygiene, may also contribute to managing and reducing breakouts. Despite being a common skin issue, the psychological impact of acne should not be underestimated, as it can affect self-esteem and overall quality of life.
Zinc is a versatile metal known for its various applications in industry and health. It is a bluish-white metallic element represented by the symbol Zn and atomic number 30 on the periodic table. Zinc is primarily used for galvanizing steel to prevent rusting, in the manufacturing of alloys, and as a component in batteries. Additionally, zinc plays a crucial role in biological processes, making it an essential trace element in the human diet. It is involved in immune function, protein synthesis, wound healing, and DNA synthesis, highlighting its importance in maintaining overall health and well-being.
Zinc has been recognized for its potential benefits in managing acne due to its anti-inflammatory properties and ability to reduce oil production in the skin. Several studies suggest that zinc supplements may help decrease the severity of acne lesions and improve overall skin health. Additionally, zinc plays a crucial role in the immune system, which can be beneficial in fighting off the bacteria that contribute to acne breakouts. For individuals struggling with moderate acne, opting for zinc supplements or using topical treatments containing zinc might offer some relief and improvement.
That said, while zinc can assist in managing acne, it is not a standalone solution, and results can vary. It’s important to combine any zinc treatment with a comprehensive skincare routine tailored to your skin type and acne severity. Consulting a dermatologist before starting any new supplement or treatment is wise, as they can offer personalized advice and the most effective treatment options for your specific situation.
Based on user reviews, individuals taking this supplement for acne have reported varying timelines for observing results. Many users note significant improvements within a few days to weeks of starting the supplement. For instance, one reviewer experienced noticeable skin improvements just three days after increasing their dose Read Review. Another mentioned that their acne healed immediately after beginning the zinc formula Read Review, indicating that users may see quick benefits.
Others have noted longer timelines, with some reporting better skin condition after a few weeks of taking the supplement consistently Read Review. Additionally, combining this supplement with other vitamins such as C and D appears to enhance its effectiveness for many users, leading to better overall results in managing acne Read Review. In summary, while some users report rapid improvement, a general timeframe of a few days to several weeks seems typical for noticing results from this supplement.
When it comes to using zinc as a supplement for treating acne, there is a notable body of scientific research that supports its potential benefits. A review of various studies indicates that zinc may have a role in reducing inflammatory symptoms associated with acne vulgaris. High doses of dietary zinc have shown promise in experimental models, suggesting that it could serve as an effective treatment option [1]. Additionally, systematic reviews have concluded that individuals with acne often have lower serum zinc levels, and those treated with zinc experienced significant reductions in acne lesions [16].
While many studies demonstrate zinc's efficacy in either standalone or combination therapies, it is crucial to highlight that the exact impact of zinc alone requires further exploration. For instance, some studies illustrate that the benefits of zinc may be enhanced when used alongside other treatments, such as isotretinoin, but its isolated effectiveness remains unclear [3]. Moreover, some investigations into the topical application of zinc compounds, including zinc oxide nanoparticles, show promising results as they tackle acne-causing bacteria effectively [5]. Overall, while zinc does appear to hold significant potential as an acne treatment, further structured clinical trials are necessary to fully establish its efficacy as a standalone solution.
Based on user reviews, many individuals have reported significant improvements in their acne symptoms after using a zinc and copper supplement. A common theme is the speed of improvement; for instance, one user noticed their acne healing almost immediately after starting the supplement Read Review. Another user highlighted that their skin condition improved markedly within just a few days, attributing this to decreased sebum production and overall better skin health Read Review. Additionally, many users noted quicker resolution of breakouts when they did occur Read Review.
Beyond speed, individuals have shared long-term benefits, including a reduction in hormonal acne and overall skin clarity Read Review. For instance, some users reported improvements in their skin after combining the supplement with other vitamins, suggesting the benefits of a comprehensive approach to skin health Read Review. While these experiences are encouraging, it's important to remember that individual results can vary based on different factors such as skin type, health conditions, and dietary habits.
While individual experiences vary, many users have reported positive outcomes when combining this zinc and copper supplement with other vitamins and nutrients for acne management. For instance, one reviewer noted significant improvements in their skin by taking the supplement alongside vitamin A, which helped decrease sebum production and improve acne within just a couple of weeks Read Review. Others have successfully paired it with vitamins C and D, enhancing their overall skin health and immune support Read Review.
A user who combined this supplement with iodine, selenium, and B vitamins reported an overall enhancement in their facial skin condition and immunity while experiencing fewer acne issues Read Review. Another reviewer highlighted the benefits of a comprehensive approach, suggesting that combining the supplement with other forms of care can lead to better results in managing acne Read Review. Overall, multiple users advocate for this synergistic approach, pointing to the efficacy of stackable nutrients in achieving clearer skin.
According to recent research, high-dose dietary zinc presents a promising approach for treating acne. Findings from studies indicate that this approach may help reduce inflammation linked to acne vulgaris, as evidenced by successful outcomes in an acne mouse model where high doses of zinc were employed [1]. A different study noted that zinc sulfate, particularly at a 5% concentration, contributed positively to reducing acne rosacea symptoms, with about 40% to 60% of patients experiencing significant relief [2]. While a specific optimal dose was not universally established, it is clear that higher doses could be beneficial.
Moreover, a systematic review highlights that individuals with acne generally show lower serum zinc levels, and treatments involving zinc correlate with a noteworthy decrease in inflammatory lesions [16]. However, it’s essential to approach zinc supplementation with caution, as gastrointestinal side effects were reported in some cases [5]. Overall, while high doses of dietary zinc appear to be effective for many, more targeted studies are required to delineate specific dosages and to better understand zinc’s role both as a standalone treatment and in combination with other therapies.
9
Skin improvement
5 people found this helpful
My skin has noticeably improved after taking this supplement along with vitamin A for my millet acne. Within just a few days, the sebum production decreased, and after two weeks, my skin is much better.
9
Quick acne healing
25 people found this helpful
I'm amazed at how quickly this zinc formula worked! I noticed my acne healing immediately after starting it.
9
Teenage acne solution
19 people found this helpful
Excellent quality with a bioavailable form of zinc. An ideal dosage for my teenage son, as his face is now very clear of acne. We take it alongside vitamins C and D for immunity.
9
Helps acne reduction
4 people found this helpful
This supplement really helps reduce my acne. When I do have a breakout, it clears up much quicker than before. Avoid taking it on an empty stomach to prevent nausea.
9
Hormonal acne relief
34 people found this helpful
I've consulted many doctors who all recommend this product. It contains the ideal doses for women and helped reduce my hormonal acne significantly.
9
Easily manageable acne
1 people found this helpful
The capsules are small and easy to take. I pair this with vitamin C, D, and omega-3, resulting in my acne clearing up. It's a beneficial supplement for my well-being.
9
Effective acne treatment
3 people found this helpful
Works well for acne. I took this supplement to address deficiencies and boost immunity alongside iodine, selenium, iron, B vitamins, vitamin D, lecithin, and vitamin C. It significantly improved my facial skin condition, with acne being less of an issue. I also noticed an enhancement in my immunity. No impact on grey hair, however.
8
Helpful factor
The quality is acceptable, and the ingredients are good. It helped me with my acne while I followed a comprehensive care routine.
8
Zinc treatment shows promise for acne
Comparative transcriptome analysis of acne vulgaris, rosacea, and hidradenitis suppurativa supports high-dose dietary zinc as a therapeutic agent.
We explored how zinc treatment may help with inflammatory skin conditions like acne vulgaris, rosacea, and hidradenitis suppurativa. These conditions can appear quite similar, which makes diagnosing them a bit tricky. By examining gene expression data across these three disorders, we noticed that certain zinc-binding proteins were consistently elevated in all cases.
Our hypothesis centers around these proteins possibly sequestering zinc, which could promote inflammation due to local zinc deficiency. To investigate this further, we identified high-dose dietary zinc as a potential therapeutic option. This was tested and validated in an acne mouse model, showing promising results for its effectiveness in reducing the inflammation associated with acne.
Although the study specifically highlighted the isolated effect of zinc, it strongly suggests that incorporating high doses of dietary zinc might offer a new avenue for treatment. This could be an encouraging option for those struggling with acne, pointing to a novel approach grounded in scientific findings.
8
Zinc effective for acne treatment
Serum zinc levels and efficacy of zinc treatment in acne vulgaris: A systematic review and meta-analysis.
We explored how zinc affects acne through a systematic review and meta-analysis that looked at two main questions. First, we wanted to know if there are differences in zinc levels between people with acne and those without. Second, we examined how effective zinc treatments are for managing acne.
Our findings showed that individuals with acne had noticeably lower serum zinc levels compared to those in the control group. Furthermore, when we looked at treatments, those who received zinc showed a significant reduction in their inflammatory papule count—a common symptom of acne. Importantly, we noted that side effects from zinc supplementation were similar to those seen in other treatments, suggesting that zinc is safe to use.
Overall, acne patients appear to benefit from improved zinc levels, especially when zinc is used either on its own or alongside other acne treatments. This gives hope for those looking for effective ways to tackle acne issues!
8
Zinc levels increased during treatment
Analysis of Isotretinoin-Induced Alterations in the Levels of Plasma Trace Elements: Investigation of the Relationship Between Magnesium, Phosphorus, Potassium, Zinc, and Treatment-Related Side Effects.
We observed the effects of isotretinoin on patients with acne vulgaris, particularly focusing on how zinc interacts with this treatment. During the study, plasma samples were collected from 35 participants before and after three months of isotretinoin therapy.
Interestingly, we found that zinc levels increased significantly after treatment, especially in male patients. This increase suggests that zinc may play a supportive role in managing acne alongside isotretinoin. However, it's important to note that the study did not isolate zinc's effects as a treatment on its own, which leaves some questions about its direct effectiveness for acne alone.
Additionally, we noted changes in other trace elements like phosphorus, magnesium, and potassium. These changes could indicate potential impacts on kidney function, which highlights the need for careful monitoring during isotretinoin treatment. Regardless of the promising rise in zinc levels, the overall effectiveness of zinc as a standalone treatment for acne remains unclear.
7
Zinc's role in acne unclear
Safety and Effectiveness of Oral Nutraceuticals for Treating Acne: A Systematic Review.
We delved into the effectiveness of oral zinc treatment for acne through a systematic review of randomized clinical trials. The study drew from numerous databases to pinpoint research that examined how zinc—and other nutraceuticals—could potentially alleviate acne symptoms.
Among the 42 studies reviewed, several demonstrated a possible benefit from various vitamins and botanicals, including zinc. Specifically, while zinc therapy was included, it was noted that gastrointestinal side effects were associated with it, which might deter some users. Overall, zinc's effectiveness in reducing acne lesions was not conclusively separated from other treatments, as the results showed mixed findings across different studies.
Therefore, while zinc may play a role in improving acne symptoms, it's essential for users to be aware of the potential adverse effects and the treatment's variability in individual responses. More extensive and well-structured trials are likely needed to clarify zinc's precise impact in treating acne.
We investigated how zinc treatment affects acne, particularly focusing on its potential benefits for those suffering from acne rosacea. The study observed that zinc sulfate solution at a concentration of 5% played a notable role in reducing the severity of acne rosacea symptoms.
Findings indicated that around 40% to 60% of patients experienced a moderate to good response after using zinc. This suggests that zinc could be helpful for individuals looking for alternatives or supplements in their acne treatment regimen.
However, it's important to acknowledge that while zinc showed positive results, the isolated effect of zinc alone cannot be fully determined. It might have worked in conjunction with other treatment factors, which complicates our understanding of its effectiveness.
Therefore, we emphasize the need for further studies to clarify exactly how zinc contributes to acne treatment outcomes and to evaluate its role alongside other therapies.
References
Li L, Hajam I, McGee JS, Tang Z, Zhang Y, et al. Comparative transcriptome analysis of acne vulgaris, rosacea, and hidradenitis suppurativa supports high-dose dietary zinc as a therapeutic agent. Exp Dermatol. 2024;33:e15145. doi:10.1111/exd.15145
Algarin YA, Pulumati A, Jaalouk D, Tan J, Nouri K. The role of vitamins and nutrients in rosacea. Arch Dermatol Res. 2024;316:142. doi:10.1007/s00403-024-02895-4
Akman TC, Yazici M, Atila A, Mertoglu C. Analysis of Isotretinoin-Induced Alterations in the Levels of Plasma Trace Elements: Investigation of the Relationship Between Magnesium, Phosphorus, Potassium, Zinc, and Treatment-Related Side Effects. Biol Trace Elem Res. 2024;202:4858. doi:10.1007/s12011-023-04053-9
Li L, Hajam I, McGee JS, Tang Z, Zhang Y, et al. Comparative Transcriptome Analysis of Acne vulgaris, Rosacea, and Hidradenitis Suppurativa Supports High Dose Dietary Zinc as a Therapeutic Agent. medRxiv. 2023. doi:10.1101/2023.11.28.23299152
Shields A, Ly S, Wafae B, Chang YF, Manjaly P, et al. Safety and Effectiveness of Oral Nutraceuticals for Treating Acne: A Systematic Review. JAMA Dermatol. 2023;159:1373. doi:10.1001/jamadermatol.2023.3949
Tan YY, Wong LS, Nyam KL, Wittayanarakul K, Zawawi NA, et al. Development and Evaluation of Topical Zinc Oxide Nanogels Formulation Using and Its Effect on Acne Vulgaris. Molecules. 2023;28. doi:10.3390/molecules28196749
Xiang Y, Lu J, Mao C, Zhu Y, Wang C, et al. Ultrasound-triggered interfacial engineering-based microneedle for bacterial infection acne treatment. Sci Adv. 2023;9:eadf0854. doi:10.1126/sciadv.adf0854
Towersey L, Correia P, Fajgenbaum Feiges M, Euzébio Gonçalves Junior J, Sant'Anna B, et al. Assessment of the Benefit of a Deep Cleansing Gel Containing Salicylic Acid 2%, Zinc Gluconate 0.2% and Lipohydroxy Acids 0.05% in Patients with Mild to Moderate Truncal Acne: Results from an Exploratory Study. Clin Cosmet Investig Dermatol. 2023;16:119. doi:10.2147/CCID.S394123
Salah E. Oral Zinc as a Novel Adjuvant and Sparing Therapy for Systemic Isotretinoin in Acne Vulgaris: A Preliminary Comparative Study. J Clin Aesthet Dermatol. 2022;15:58.
Naji HH, Al-Azawi RSA, Ibrahim NJ, Kzar HH. Investigation of the Role of Zn/Cu Index and its Correlation with Physiological Activity of SOD 1 and GRx in Males with Acne Vulgaris. Arch Razi Inst. 2022;77:623. doi:10.22092/ARI.2021.356857.1928
Searle T, Ali FR, Al-Niaimi F. Zinc in dermatology. J Dermatolog Treat. 2022;33:2455. doi:10.1080/09546634.2022.2062282
Poizeau F, Plantier F, Bell H, Moyal-Barracco M. Vulvar Fordyce adenitis: A cohort of 45 women. Ann Dermatol Venereol. 2021;148:221. doi:10.1016/j.annder.2021.04.001
Tolino E, Skroza N, Mambrin A, Proietti I, Bernardini N, et al. An Open-label Study Comparing Oral Zinc to Lymecycline in the Treatment of Acne Vulgaris. J Clin Aesthet Dermatol. 2021;14:56.
Maillard A, Pastor D, Merat R. Anti-PD-1-Induced Hidradenitis Suppurativa. Dermatopathology (Basel). 2021;8:37. doi:10.3390/dermatopathology8010007
Abendrot M, Płuciennik E, Felczak A, Zawadzka K, Piątczak E, et al. Zinc(II) Complexes of Amino Acids as New Active Ingredients for Anti-Acne Dermatological Preparations. Int J Mol Sci. 2021;22. doi:10.3390/ijms22041641
Yee BE, Richards P, Sui JY, Marsch AF. Serum zinc levels and efficacy of zinc treatment in acne vulgaris: A systematic review and meta-analysis. Dermatol Ther. 2020;33:e14252. doi:10.1111/dth.14252