The study focused on understanding how dietary copper affects physiological issues tied to reduced levels of peptidylglycine alpha-amidating monooxygenase (PAM), especially regarding hypothyroidism.
We evaluated the impact of PAM deficiencies in mice and found that those with reduced PAM levels struggled with thyroid regulation and body temperature, particularly when they were hypothyroid due to dietary restrictions. Interestingly, while these mice showed normal hormone response to cold, they couldn't maintain their body temperature effectively as compared to their healthy counterparts in colder environments.
However, when we introduced additional dietary copper, these PAM-deficient mice were able to stabilize their body temperature just as effectively as the normal mice. It appeared that copper supplementation helped restore some of the physiological functions that were impaired by low PAM levels.
Overall, our findings indicate that low dietary copper might exacerbate the challenges faced by those with PAM deficiencies, suggesting that copper intake could be an important factor in managing related hypothyroidism symptoms.
Read More
7
Zinc's uncertain role in hypothyroidism
The Effect of Some Micronutrients Multi-Supplementation on Thyroid Function, Metabolic Features and Quality of Life in Patients Treating With Levothyroxine and Vitamin D: A Double-blind, Randomized Controlled Trial.
We conducted a study to investigate the effects of micronutrient supplementation, including zinc, on thyroid function and overall quality of life in patients with hypothyroidism. Our trial involved 104 participants who were receiving levothyroxine and vitamin D. They were randomly assigned to either a group that received a mix of essential nutrients or a placebo group over eight weeks.
We measured various health markers before and after this period, including thyroid hormone levels, cholesterol, insulin resistance, and blood pressure. Our findings suggested that the group receiving the micronutrient supplement experienced improvements in insulin resistance and overall quality of life. However, it’s important to note that the specific effects of zinc alone are somewhat difficult to isolate, as it was part of a combination of nutrients being tested.
Ultimately, while the study indicates potential benefits of micronutrient supplementation for thyroid function in hypothyroid patients, further trials are necessary to clearly define the role of zinc and other nutrients in this context.
Read More
Most Useful Reviews
9
Immune support benefits
20 people found this helpful
Excellent zinc composition! Chelated zinc can be taken alongside copper. I purchased it during viral infections, and it has been immensely helpful. For optimal immunity against colds and flu, I recommend 30 mg of zinc with 1000 mg of Vitamin C every two hours. I also appreciate its benefits for hypothyroidism, gut health, and overall wellbeing.
Read More
9
Essential supplement
The value for money is excellent! Zinc is crucial for my hypothyroidism, and I can’t recommend it highly enough.
Read More
9
Mineral synergy
I recommend this zinc and copper complex! It’s essential for my hypothyroidism. This high-quality supplement, along with selenium, magnesium, and vitamin D, has improved my tests and overall immunity. The capsules are easy to swallow.
The study focused on understanding how dietary copper affects physiological issues tied to reduced levels of peptidylglycine alpha-amidating monooxygenase (PAM), especially regarding hypothyroidism.
We evaluated the impact of PAM deficiencies in mice and found that those with reduced PAM levels struggled with thyroid regulation and body temperature, particularly when they were hypothyroid due to dietary restrictions. Interestingly, while these mice showed normal hormone response to cold, they couldn't maintain their body temperature effectively as compared to their healthy counterparts in colder environments.
However, when we introduced additional dietary copper, these PAM-deficient mice were able to stabilize their body temperature just as effectively as the normal mice. It appeared that copper supplementation helped restore some of the physiological functions that were impaired by low PAM levels.
Overall, our findings indicate that low dietary copper might exacerbate the challenges faced by those with PAM deficiencies, suggesting that copper intake could be an important factor in managing related hypothyroidism symptoms.
Read More
7
Zinc's uncertain role in hypothyroidism
The Effect of Some Micronutrients Multi-Supplementation on Thyroid Function, Metabolic Features and Quality of Life in Patients Treating With Levothyroxine and Vitamin D: A Double-blind, Randomized Controlled Trial.
We conducted a study to investigate the effects of micronutrient supplementation, including zinc, on thyroid function and overall quality of life in patients with hypothyroidism. Our trial involved 104 participants who were receiving levothyroxine and vitamin D. They were randomly assigned to either a group that received a mix of essential nutrients or a placebo group over eight weeks.
We measured various health markers before and after this period, including thyroid hormone levels, cholesterol, insulin resistance, and blood pressure. Our findings suggested that the group receiving the micronutrient supplement experienced improvements in insulin resistance and overall quality of life. However, it’s important to note that the specific effects of zinc alone are somewhat difficult to isolate, as it was part of a combination of nutrients being tested.
Ultimately, while the study indicates potential benefits of micronutrient supplementation for thyroid function in hypothyroid patients, further trials are necessary to clearly define the role of zinc and other nutrients in this context.
Read More
User Reviews
USERS' SCORE
Good
Based on 10 Reviews
8.4
All Reviews
Positive Reviews
Negative Reviews
9
Immune support benefits
20 people found this helpful
Excellent zinc composition! Chelated zinc can be taken alongside copper. I purchased it during viral infections, and it has been immensely helpful. For optimal immunity against colds and flu, I recommend 30 mg of zinc with 1000 mg of Vitamin C every two hours. I also appreciate its benefits for hypothyroidism, gut health, and overall wellbeing.
Read More
9
Essential supplement
The value for money is excellent! Zinc is crucial for my hypothyroidism, and I can’t recommend it highly enough.
Read More
9
Mineral synergy
I recommend this zinc and copper complex! It’s essential for my hypothyroidism. This high-quality supplement, along with selenium, magnesium, and vitamin D, has improved my tests and overall immunity. The capsules are easy to swallow.
Read More
9
Affordable quality
This high-quality zinc and copper supplement is affordable. It’s the perfect option for managing hypothyroidism. Easy to take, with no taste or odour, I trust Jarrow Formulas and have consistently been satisfied with their products.
Read More
9
Energy restoration
An excellent supplement! Prescribed for my hypothyroidism and to improve thyroid function, I'm noticing heightened vitality and a significant lift in my spirits after a month of use.
Hypothyroidism is a medical condition that occurs when the thyroid gland, a small butterfly-shaped gland located at the base of the neck, does not produce enough thyroid hormones. These hormones, mainly thyroxine (T4) and triiodothyronine (T3), play a critical role in regulating various bodily functions, including metabolism, energy production, and overall growth and development. When hormone levels drop, it can lead to a slow metabolism, weight gain, fatigue, depression, and a host of other symptoms that can significantly affect quality of life.
The condition can be caused by a variety of factors, including autoimmune diseases like Hashimoto's thyroiditis, certain medications, radiation treatment, or iodine deficiency. Diagnosis typically involves blood tests to check levels of thyroid-stimulating hormone (TSH) and thyroid hormones. Treatment primarily includes hormone replacement therapy, with synthetic thyroid hormones such as levothyroxine being the most common form of treatment. With proper management, individuals with hypothyroidism can lead normal, healthy lives by ensuring they receive the necessary hormones their bodies need to function optimally.
Zinc is a versatile metal known for its various applications in industry and health. It is a bluish-white metallic element represented by the symbol Zn and atomic number 30 on the periodic table. Zinc is primarily used for galvanizing steel to prevent rusting, in the manufacturing of alloys, and as a component in batteries. Additionally, zinc plays a crucial role in biological processes, making it an essential trace element in the human diet. It is involved in immune function, protein synthesis, wound healing, and DNA synthesis, highlighting its importance in maintaining overall health and well-being.
While zinc is an essential mineral important for various bodily functions, including immune response and protein synthesis, its role in managing hypothyroidism is not straightforward. Some studies suggest that zinc is vital for the synthesis of thyroid hormones and may help in the conversion of T4 (thyroxine) to T3 (triiodothyronine), the more active form of thyroid hormone. Therefore, maintaining adequate zinc levels could potentially support thyroid function, particularly in individuals who are zinc deficient.
However, supplementation should not replace conventional treatments for hypothyroidism, such as thyroid hormone replacement therapy. Always consult with a healthcare provider before starting any new supplements, especially if you have an existing medical condition or are on medication. They can guide you on appropriate doses, dietary sources of zinc, and determine if supplementation is necessary based on your individual health needs and lab results.
Based on user reviews for zinc supplements taken for hypothyroidism, many users report noticing positive changes in their health after about a month of consistent use. One user mentioned feeling heightened vitality and a significant improvement in their mood after a month of use, suggesting this timeframe as a typical duration for observing benefits Read Review. Another user emphasized the importance of taking zinc regularly to support thyroid health, which is essential for those managing hypothyroidism Read Review.
While individuals may experience varying results depending on their health status, diet, and the severity of their deficiency, the general consensus seems to point towards a month as a reasonable time frame to expect to see results from supplementing with zinc. Users highlight that, with consistent daily use, the supplements have played a crucial role in supporting their overall wellbeing alongside other treatments Read Review.
The scientific research surrounding supplements for hypothyroidism shows promising avenues, particularly regarding micronutrient supplementation. A study involving 104 participants with hypothyroidism highlighted potential benefits of a mixed micronutrient supplement, which included zinc. Over eight weeks, participants receiving the supplement exhibited improvements in insulin resistance and overall quality of life. However, the specific impact of zinc alone could not be distinctly measured, as it was part of a broader group of nutrients tested ([1]). This indicates that while micronutrient supplements may support thyroid health, more research is needed to determine the isolated effects of specific elements like zinc on hypothyroidism.
Additionally, dietary copper was found to play a significant role in managing hypothyroidism symptoms linked to deficiencies in peptidylglycine alpha-amidating monooxygenase (PAM). In mice studies, those with PAM deficiencies exhibited struggles with thyroid regulation, yet supplemental copper helped restore some of those physiological functions, indicating its potential relevance for individuals facing similar challenges in hypothyroidism management ([2]). Overall, while there are indications that supplements could benefit hypothyroid patients, further targeted studies are essential to clarify their effectiveness and optimal use.
Based on user reviews, individuals supplementing with zinc for hypothyroidism generally report positive improvements in their symptoms. Many users indicate feeling better overall, with one noting a marked boost in vitality and mood after consistently using the supplement for a month Read Review. Another user mentioned that zinc is crucial for supporting the thyroid gland and has helped improve their wellbeing during viral infections Read Review. Additionally, users have highlighted enhanced immunity and overall health, emphasizing zinc's essential role in thyroid hormone production and gut health, especially for those at risk of deficiency Read Review.
Most reviewers point to zinc as beneficial in managing their hypothyroid symptoms, with many also pairing it with other supplements, like copper and selenium, for added health improvements Read Review. It's important to note, however, that individual results can vary depending on health conditions, the severity of deficiency, and personal responsiveness to the supplement. While many appreciate the improved recovery times from colds, consistency in taking zinc seems to be a critical factor in achieving these benefits Read Review.
Users report positive outcomes when combining this zinc supplement with other nutrients to effectively manage their hypothyroidism. A number of reviewers have highlighted the synergy of zinc with copper, selenium, and magnesium, stating that these combinations can enhance overall health. For example, one user shared that their regimen included zinc and copper along with selenium and vitamin D, which notably improved their test results and boosted their immunity Read Review. Another reviewer noted taking zinc alongside vitamin C for its immunity benefits during cold season, explicitly mentioning how these supplements collectively support their health Read Review.
Furthermore, users emphasize the importance of maintaining balanced levels of these minerals, as some express concerns about zinc potentially displacing copper with higher doses Read Review. Nevertheless, many continue to advocate for the integration of these supplements, affirming that they play a crucial role in managing hypothyroid symptoms and supporting thyroid function Read Review. Overall, the consensus from user reviews suggests that a thoughtful combination of zinc with other essential supplements can lead to improved outcomes for those dealing with hypothyroidism.
Users report varying recommendations for the right dose of Zinc for treating hypothyroidism, emphasizing its importance in managing the condition. One user suggests taking 30 mg of zinc alongside 1000 mg of Vitamin C every two hours, especially during viral infections and for overall immunological support Read Review. Another user mentions taking one capsule daily as prescribed by their endocrinologist, indicating this dosage to be effective and beneficial Read Review.
Several reviews highlight the significance of zinc in thyroid hormone production and overall health for those dealing with hypothyroidism. Users have noted improvements in their conditions and vitality with consistent zinc supplementation, which further underscores the importance of proper dosing Read Review. Overall, while specific dosages may vary, the consensus suggests that a daily intake of zinc, whether combined with other minerals or taken alone, can be immensely beneficial for those managing hypothyroidism.
9
Energy restoration
An excellent supplement! Prescribed for my hypothyroidism and to improve thyroid function, I'm noticing heightened vitality and a significant lift in my spirits after a month of use.
7.5
Thyroid health aid
1 people found this helpful
I always keep zinc in my medicine cabinet. Whenever I catch a cold, I start taking it. This product has copper which can be concerning as zinc may displace it, but the dosage is small. Zinc is crucial for supporting the thyroid gland, especially for those with hypothyroidism.
9
Immune support benefits
20 people found this helpful
Excellent zinc composition! Chelated zinc can be taken alongside copper. I purchased it during viral infections, and it has been immensely helpful. For optimal immunity against colds and flu, I recommend 30 mg of zinc with 1000 mg of Vitamin C every two hours. I also appreciate its benefits for hypothyroidism, gut health, and overall wellbeing.
7.5
Deficiency prevention
1 people found this helpful
Zinc is vital for gut health, immune function, and thyroid hormone production, especially for those with hypothyroidism who are at risk of deficiency. Symptoms of insufficiency include poor healing and brittle hair. I take zinc to ensure I maintain adequate levels while managing my condition.
9
Mineral synergy
I recommend this zinc and copper complex! It’s essential for my hypothyroidism. This high-quality supplement, along with selenium, magnesium, and vitamin D, has improved my tests and overall immunity. The capsules are easy to swallow.
6
Form concerns
2 people found this helpful
My doctor recommended this zinc, but I've read that zinc sulfate might be toxic and cause nausea. I take it for my hypothyroidism; I notice less recovery time from colds, but I will switch forms after finishing this one.
7.5
Recommended dosage
1 people found this helpful
I take one capsule daily after meals, as prescribed by my endocrinologist for my hypothyroidism. The dosage is effective and beneficial.
7
Zinc's uncertain role in hypothyroidism
The Effect of Some Micronutrients Multi-Supplementation on Thyroid Function, Metabolic Features and Quality of Life in Patients Treating With Levothyroxine and Vitamin D: A Double-blind, Randomized Controlled Trial.
We conducted a study to investigate the effects of micronutrient supplementation, including zinc, on thyroid function and overall quality of life in patients with hypothyroidism. Our trial involved 104 participants who were receiving levothyroxine and vitamin D. They were randomly assigned to either a group that received a mix of essential nutrients or a placebo group over eight weeks.
We measured various health markers before and after this period, including thyroid hormone levels, cholesterol, insulin resistance, and blood pressure. Our findings suggested that the group receiving the micronutrient supplement experienced improvements in insulin resistance and overall quality of life. However, it’s important to note that the specific effects of zinc alone are somewhat difficult to isolate, as it was part of a combination of nutrients being tested.
Ultimately, while the study indicates potential benefits of micronutrient supplementation for thyroid function in hypothyroid patients, further trials are necessary to clearly define the role of zinc and other nutrients in this context.
8
Copper supplementation aids hypothyroidism
Reversal of physiological deficits caused by diminished levels of peptidylglycine alpha-amidating monooxygenase by dietary copper.
The study focused on understanding how dietary copper affects physiological issues tied to reduced levels of peptidylglycine alpha-amidating monooxygenase (PAM), especially regarding hypothyroidism.
We evaluated the impact of PAM deficiencies in mice and found that those with reduced PAM levels struggled with thyroid regulation and body temperature, particularly when they were hypothyroid due to dietary restrictions. Interestingly, while these mice showed normal hormone response to cold, they couldn't maintain their body temperature effectively as compared to their healthy counterparts in colder environments.
However, when we introduced additional dietary copper, these PAM-deficient mice were able to stabilize their body temperature just as effectively as the normal mice. It appeared that copper supplementation helped restore some of the physiological functions that were impaired by low PAM levels.
Overall, our findings indicate that low dietary copper might exacerbate the challenges faced by those with PAM deficiencies, suggesting that copper intake could be an important factor in managing related hypothyroidism symptoms.
References
Nikkhah M, Vafa M, Abiri B, Golgiri F, Sarbakhsh P, et al. The Effect of Some Micronutrients Multi-Supplementation on Thyroid Function, Metabolic Features and Quality of Life in Patients Treating With Levothyroxine and Vitamin D: A Double-blind, Randomized Controlled Trial. Med J Islam Repub Iran. 2024;38:133. doi:10.47176/mjiri.38.133
Bousquet-Moore D, Ma XM, Nillni EA, Czyzyk TA, Pintar JE, et al. Reversal of physiological deficits caused by diminished levels of peptidylglycine alpha-amidating monooxygenase by dietary copper. Endocrinology. 2009;150:1739. doi:10.1210/en.2008-1202