Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.4
USERS' SCORE
Good
Based on 3 Reviews
8.2
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Zinc (as Zinc L-Methionine Sulfate)
15 mg
136%
Copper (as Gluconate)
1 mg
111%
Top Medical Research Studies
9
Zinc enhances vitamin D in menopause
We set out to understand how zinc supplementation could affect vitamin D status and leptin levels in postmenopausal women. The study involved 51 healthy postmenopausal women aged between 44 and 76 from Granada, Spain. They were divided into two groups: one receiving a zinc supplement of 50 mg daily for eight weeks and the other receiving a placebo.
Our findings revealed that zinc supplementation significantly improved vitamin D status in these women. Particularly, those who had reached menopause at a younger age saw a notable increase in their vitamin D levels after taking zinc.
Additionally, we discovered a connection between zinc and leptin levels, a hormone that regulates energy balance. Both dietary zinc intake and its plasma levels were found to be inversely related to serum leptin levels—meaning as zinc levels increased, leptin levels tended to decrease.
Overall, these results suggest that zinc supplementation may play a beneficial role during menopause by enhancing vitamin D levels and influencing leptin balance among postmenopausal women.
Our findings revealed that zinc supplementation significantly improved vitamin D status in these women. Particularly, those who had reached menopause at a younger age saw a notable increase in their vitamin D levels after taking zinc.
Additionally, we discovered a connection between zinc and leptin levels, a hormone that regulates energy balance. Both dietary zinc intake and its plasma levels were found to be inversely related to serum leptin levels—meaning as zinc levels increased, leptin levels tended to decrease.
Overall, these results suggest that zinc supplementation may play a beneficial role during menopause by enhancing vitamin D levels and influencing leptin balance among postmenopausal women.
Read More
9
We evaluated the impact of a zinc-containing vaginal moisturizer gel on postmenopausal women experiencing genitourinary symptoms of menopause (GSM). Some women hesitate to use hormonal treatments like vaginal estrogen, which can be highly effective. To explore an alternative, we asked 37 participants to apply the gel daily for two weeks while tracking their symptoms.
Throughout the study, we used various methods to assess improvement. The Vaginal Health Index, which measures vaginal health, showed significant improvement after treatment. We also noted that participants reported reduced levels of vaginal pain and dryness on a visual analog scale, with the most notable benefit occurring for vaginal dryness. Additionally, the vulvovaginal symptom questionnaire indicated a substantial decrease in overall symptoms. Notably, side effects were minor and infrequent, which is encouraging for those considering this option.
In summary, our findings suggest that a novel zinc-containing vaginal moisturizer gel can effectively alleviate postmenopausal vulvovaginal symptoms without serious side effects, providing a viable solution for women who prefer non-hormonal treatments.
Throughout the study, we used various methods to assess improvement. The Vaginal Health Index, which measures vaginal health, showed significant improvement after treatment. We also noted that participants reported reduced levels of vaginal pain and dryness on a visual analog scale, with the most notable benefit occurring for vaginal dryness. Additionally, the vulvovaginal symptom questionnaire indicated a substantial decrease in overall symptoms. Notably, side effects were minor and infrequent, which is encouraging for those considering this option.
In summary, our findings suggest that a novel zinc-containing vaginal moisturizer gel can effectively alleviate postmenopausal vulvovaginal symptoms without serious side effects, providing a viable solution for women who prefer non-hormonal treatments.
Read More
8
Zinc enhances antioxidant protection
We assessed how zinc (Zn) supplementation can impact the health of postmenopausal women, particularly regarding their antioxidant status. In this study, fifty-one women participating were split into two groups: one receiving a placebo treatment and the other receiving zinc supplements. This double-blind randomized trial lasted for eight weeks and focused on measuring changes in mineral status along with different antioxidant markers in the blood.
Before the intervention, we noticed that many participants had low zinc levels, which can lead to weakened antioxidant defenses—especially critical for postmenopausal women due to hormonal changes. After eight weeks of zinc supplementation, we saw a marked improvement in zinc levels among the women receiving the supplements. There were also significant positive correlations between zinc levels and overall antioxidant capacity, as well as specific antioxidant enzymes like glutathione peroxidase.
From our findings, it seems clear that zinc supplementation is a promising way to address deficiencies and bolster antioxidant defenses in postmenopausal women. This could not only support their nutritional health but might also contribute positively to their overall well-being during this transitional life stage.
Before the intervention, we noticed that many participants had low zinc levels, which can lead to weakened antioxidant defenses—especially critical for postmenopausal women due to hormonal changes. After eight weeks of zinc supplementation, we saw a marked improvement in zinc levels among the women receiving the supplements. There were also significant positive correlations between zinc levels and overall antioxidant capacity, as well as specific antioxidant enzymes like glutathione peroxidase.
From our findings, it seems clear that zinc supplementation is a promising way to address deficiencies and bolster antioxidant defenses in postmenopausal women. This could not only support their nutritional health but might also contribute positively to their overall well-being during this transitional life stage.
Read More
Most Useful Reviews
10
Helpful during menopause
I find this product incredibly helpful for my menopause. It has made me feel much better.
Read More
7.5
Healthy nails
26 people found this helpful
Fixing My Flaky Fingernails. Since starting menopause, my nails suffered greatly, losing integrity to the point where I couldn't get fake nails for my daughter's wedding. I already used biotin and other supplements, so this was my last resort. Though I haven't finished the bottle, I've seen remarkable improvement and healthy growth after just a week. This is the only solution showing results.
Read More
4
Supports healthy weight
This product regulates fat metabolism, helping to maintain a healthy weight; reduces the risk of osteoporosis during menopause; and promotes healthy skin, hair, and nails. Additionally, it supports the mother and fetus during pregnancy.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.4
- All Researches
9
Zinc enhances vitamin D in menopause
We set out to understand how zinc supplementation could affect vitamin D status and leptin levels in postmenopausal women. The study involved 51 healthy postmenopausal women aged between 44 and 76 from Granada, Spain. They were divided into two groups: one receiving a zinc supplement of 50 mg daily for eight weeks and the other receiving a placebo.
Our findings revealed that zinc supplementation significantly improved vitamin D status in these women. Particularly, those who had reached menopause at a younger age saw a notable increase in their vitamin D levels after taking zinc.
Additionally, we discovered a connection between zinc and leptin levels, a hormone that regulates energy balance. Both dietary zinc intake and its plasma levels were found to be inversely related to serum leptin levels—meaning as zinc levels increased, leptin levels tended to decrease.
Overall, these results suggest that zinc supplementation may play a beneficial role during menopause by enhancing vitamin D levels and influencing leptin balance among postmenopausal women.
Our findings revealed that zinc supplementation significantly improved vitamin D status in these women. Particularly, those who had reached menopause at a younger age saw a notable increase in their vitamin D levels after taking zinc.
Additionally, we discovered a connection between zinc and leptin levels, a hormone that regulates energy balance. Both dietary zinc intake and its plasma levels were found to be inversely related to serum leptin levels—meaning as zinc levels increased, leptin levels tended to decrease.
Overall, these results suggest that zinc supplementation may play a beneficial role during menopause by enhancing vitamin D levels and influencing leptin balance among postmenopausal women.
Read More
9
We evaluated the impact of a zinc-containing vaginal moisturizer gel on postmenopausal women experiencing genitourinary symptoms of menopause (GSM). Some women hesitate to use hormonal treatments like vaginal estrogen, which can be highly effective. To explore an alternative, we asked 37 participants to apply the gel daily for two weeks while tracking their symptoms.
Throughout the study, we used various methods to assess improvement. The Vaginal Health Index, which measures vaginal health, showed significant improvement after treatment. We also noted that participants reported reduced levels of vaginal pain and dryness on a visual analog scale, with the most notable benefit occurring for vaginal dryness. Additionally, the vulvovaginal symptom questionnaire indicated a substantial decrease in overall symptoms. Notably, side effects were minor and infrequent, which is encouraging for those considering this option.
In summary, our findings suggest that a novel zinc-containing vaginal moisturizer gel can effectively alleviate postmenopausal vulvovaginal symptoms without serious side effects, providing a viable solution for women who prefer non-hormonal treatments.
Throughout the study, we used various methods to assess improvement. The Vaginal Health Index, which measures vaginal health, showed significant improvement after treatment. We also noted that participants reported reduced levels of vaginal pain and dryness on a visual analog scale, with the most notable benefit occurring for vaginal dryness. Additionally, the vulvovaginal symptom questionnaire indicated a substantial decrease in overall symptoms. Notably, side effects were minor and infrequent, which is encouraging for those considering this option.
In summary, our findings suggest that a novel zinc-containing vaginal moisturizer gel can effectively alleviate postmenopausal vulvovaginal symptoms without serious side effects, providing a viable solution for women who prefer non-hormonal treatments.
Read More
8
Zinc enhances antioxidant protection
We assessed how zinc (Zn) supplementation can impact the health of postmenopausal women, particularly regarding their antioxidant status. In this study, fifty-one women participating were split into two groups: one receiving a placebo treatment and the other receiving zinc supplements. This double-blind randomized trial lasted for eight weeks and focused on measuring changes in mineral status along with different antioxidant markers in the blood.
Before the intervention, we noticed that many participants had low zinc levels, which can lead to weakened antioxidant defenses—especially critical for postmenopausal women due to hormonal changes. After eight weeks of zinc supplementation, we saw a marked improvement in zinc levels among the women receiving the supplements. There were also significant positive correlations between zinc levels and overall antioxidant capacity, as well as specific antioxidant enzymes like glutathione peroxidase.
From our findings, it seems clear that zinc supplementation is a promising way to address deficiencies and bolster antioxidant defenses in postmenopausal women. This could not only support their nutritional health but might also contribute positively to their overall well-being during this transitional life stage.
Before the intervention, we noticed that many participants had low zinc levels, which can lead to weakened antioxidant defenses—especially critical for postmenopausal women due to hormonal changes. After eight weeks of zinc supplementation, we saw a marked improvement in zinc levels among the women receiving the supplements. There were also significant positive correlations between zinc levels and overall antioxidant capacity, as well as specific antioxidant enzymes like glutathione peroxidase.
From our findings, it seems clear that zinc supplementation is a promising way to address deficiencies and bolster antioxidant defenses in postmenopausal women. This could not only support their nutritional health but might also contribute positively to their overall well-being during this transitional life stage.
Read More
8
Zinc improves nutritional markers post-menopause
In our study, we examined how zinc supplementation could affect menopausal women, particularly focusing on markers like homocysteine, vitamin B, and folate levels. We worked with 51 postmenopausal women aged between 44 and 76 years, dividing them into two groups: one received a placebo, while the other was given 50 mg of zinc daily for eight weeks.
After analyzing the results, we found that those who took zinc showed significantly higher folate levels compared to their baseline measurements. Additionally, we observed a noteworthy decrease in homocysteine levels when comparing the two groups after the intervention. Interestingly, we also noted a strong correlation between higher folate and vitamin B levels with lower homocysteine levels in the zinc group.
These findings suggest that zinc supplementation can have positive effects on certain nutritional markers in menopausal women. However, we emphasize the need for further research with larger sample sizes and refined dosing to validate and expand upon our results.
After analyzing the results, we found that those who took zinc showed significantly higher folate levels compared to their baseline measurements. Additionally, we observed a noteworthy decrease in homocysteine levels when comparing the two groups after the intervention. Interestingly, we also noted a strong correlation between higher folate and vitamin B levels with lower homocysteine levels in the zinc group.
These findings suggest that zinc supplementation can have positive effects on certain nutritional markers in menopausal women. However, we emphasize the need for further research with larger sample sizes and refined dosing to validate and expand upon our results.
Read More
7
We investigated the effects of dietary zinc on obesity related to menopause, particularly in female mice that underwent ovariectomy (Ovx). Our findings revealed that excess zinc led to significant weight gain and symptoms resembling Cushing's syndrome, even though these mice did not consume more food.
The accumulation of zinc in the adrenal glands played a crucial role by interfering with steroid production. This is particularly important since, in Ovx mice, adrenal steroids are the only source of estrogen. The lack of estrogen triggered adrenal hyperplasia and an increase in glucocorticoids, which contributed to the development of Cushing's-like symptoms.
Interestingly, our results showed that supplementing with adrenal steroids could counteract the negative impacts of excess zinc. We also found a positive correlation between plasma zinc levels and cortisol while noting a negative correlation with adrenal steroids and estrogen levels in overweight postmenopausal women.
These insights suggest that it may be beneficial for postmenopausal women to avoid high dietary zinc and consider adrenal steroid supplementation to help manage obesity effectively.
The accumulation of zinc in the adrenal glands played a crucial role by interfering with steroid production. This is particularly important since, in Ovx mice, adrenal steroids are the only source of estrogen. The lack of estrogen triggered adrenal hyperplasia and an increase in glucocorticoids, which contributed to the development of Cushing's-like symptoms.
Interestingly, our results showed that supplementing with adrenal steroids could counteract the negative impacts of excess zinc. We also found a positive correlation between plasma zinc levels and cortisol while noting a negative correlation with adrenal steroids and estrogen levels in overweight postmenopausal women.
These insights suggest that it may be beneficial for postmenopausal women to avoid high dietary zinc and consider adrenal steroid supplementation to help manage obesity effectively.
Read More
User Reviews
USERS' SCORE
Good
Based on 3 Reviews
8.2
- All Reviews
- Positive Reviews
- Negative Reviews
10
Helpful during menopause
I find this product incredibly helpful for my menopause. It has made me feel much better.
Read More
7.5
Healthy nails
26 people found this helpful
Fixing My Flaky Fingernails. Since starting menopause, my nails suffered greatly, losing integrity to the point where I couldn't get fake nails for my daughter's wedding. I already used biotin and other supplements, so this was my last resort. Though I haven't finished the bottle, I've seen remarkable improvement and healthy growth after just a week. This is the only solution showing results.
Read More
4
Supports healthy weight
This product regulates fat metabolism, helping to maintain a healthy weight; reduces the risk of osteoporosis during menopause; and promotes healthy skin, hair, and nails. Additionally, it supports the mother and fetus during pregnancy.
Read More
Frequently Asked Questions
10
Helpful during menopause
I find this product incredibly helpful for my menopause. It has made me feel much better.
4
Supports healthy weight
This product regulates fat metabolism, helping to maintain a healthy weight; reduces the risk of osteoporosis during menopause; and promotes healthy skin, hair, and nails. Additionally, it supports the mother and fetus during pregnancy.
8
Zinc enhances antioxidant protection
We assessed how zinc (Zn) supplementation can impact the health of postmenopausal women, particularly regarding their antioxidant status. In this study, fifty-one women participating were split into two groups: one receiving a placebo treatment and the other receiving zinc supplements. This double-blind randomized trial lasted for eight weeks and focused on measuring changes in mineral status along with different antioxidant markers in the blood.
Before the intervention, we noticed that many participants had low zinc levels, which can lead to weakened antioxidant defenses—especially critical for postmenopausal women due to hormonal changes. After eight weeks of zinc supplementation, we saw a marked improvement in zinc levels among the women receiving the supplements. There were also significant positive correlations between zinc levels and overall antioxidant capacity, as well as specific antioxidant enzymes like glutathione peroxidase.
From our findings, it seems clear that zinc supplementation is a promising way to address deficiencies and bolster antioxidant defenses in postmenopausal women. This could not only support their nutritional health but might also contribute positively to their overall well-being during this transitional life stage.
Before the intervention, we noticed that many participants had low zinc levels, which can lead to weakened antioxidant defenses—especially critical for postmenopausal women due to hormonal changes. After eight weeks of zinc supplementation, we saw a marked improvement in zinc levels among the women receiving the supplements. There were also significant positive correlations between zinc levels and overall antioxidant capacity, as well as specific antioxidant enzymes like glutathione peroxidase.
From our findings, it seems clear that zinc supplementation is a promising way to address deficiencies and bolster antioxidant defenses in postmenopausal women. This could not only support their nutritional health but might also contribute positively to their overall well-being during this transitional life stage.
9
Zinc enhances vitamin D in menopause
We set out to understand how zinc supplementation could affect vitamin D status and leptin levels in postmenopausal women. The study involved 51 healthy postmenopausal women aged between 44 and 76 from Granada, Spain. They were divided into two groups: one receiving a zinc supplement of 50 mg daily for eight weeks and the other receiving a placebo.
Our findings revealed that zinc supplementation significantly improved vitamin D status in these women. Particularly, those who had reached menopause at a younger age saw a notable increase in their vitamin D levels after taking zinc.
Additionally, we discovered a connection between zinc and leptin levels, a hormone that regulates energy balance. Both dietary zinc intake and its plasma levels were found to be inversely related to serum leptin levels—meaning as zinc levels increased, leptin levels tended to decrease.
Overall, these results suggest that zinc supplementation may play a beneficial role during menopause by enhancing vitamin D levels and influencing leptin balance among postmenopausal women.
Our findings revealed that zinc supplementation significantly improved vitamin D status in these women. Particularly, those who had reached menopause at a younger age saw a notable increase in their vitamin D levels after taking zinc.
Additionally, we discovered a connection between zinc and leptin levels, a hormone that regulates energy balance. Both dietary zinc intake and its plasma levels were found to be inversely related to serum leptin levels—meaning as zinc levels increased, leptin levels tended to decrease.
Overall, these results suggest that zinc supplementation may play a beneficial role during menopause by enhancing vitamin D levels and influencing leptin balance among postmenopausal women.
9
We evaluated the impact of a zinc-containing vaginal moisturizer gel on postmenopausal women experiencing genitourinary symptoms of menopause (GSM). Some women hesitate to use hormonal treatments like vaginal estrogen, which can be highly effective. To explore an alternative, we asked 37 participants to apply the gel daily for two weeks while tracking their symptoms.
Throughout the study, we used various methods to assess improvement. The Vaginal Health Index, which measures vaginal health, showed significant improvement after treatment. We also noted that participants reported reduced levels of vaginal pain and dryness on a visual analog scale, with the most notable benefit occurring for vaginal dryness. Additionally, the vulvovaginal symptom questionnaire indicated a substantial decrease in overall symptoms. Notably, side effects were minor and infrequent, which is encouraging for those considering this option.
In summary, our findings suggest that a novel zinc-containing vaginal moisturizer gel can effectively alleviate postmenopausal vulvovaginal symptoms without serious side effects, providing a viable solution for women who prefer non-hormonal treatments.
Throughout the study, we used various methods to assess improvement. The Vaginal Health Index, which measures vaginal health, showed significant improvement after treatment. We also noted that participants reported reduced levels of vaginal pain and dryness on a visual analog scale, with the most notable benefit occurring for vaginal dryness. Additionally, the vulvovaginal symptom questionnaire indicated a substantial decrease in overall symptoms. Notably, side effects were minor and infrequent, which is encouraging for those considering this option.
In summary, our findings suggest that a novel zinc-containing vaginal moisturizer gel can effectively alleviate postmenopausal vulvovaginal symptoms without serious side effects, providing a viable solution for women who prefer non-hormonal treatments.
8
Zinc improves nutritional markers post-menopause
In our study, we examined how zinc supplementation could affect menopausal women, particularly focusing on markers like homocysteine, vitamin B, and folate levels. We worked with 51 postmenopausal women aged between 44 and 76 years, dividing them into two groups: one received a placebo, while the other was given 50 mg of zinc daily for eight weeks.
After analyzing the results, we found that those who took zinc showed significantly higher folate levels compared to their baseline measurements. Additionally, we observed a noteworthy decrease in homocysteine levels when comparing the two groups after the intervention. Interestingly, we also noted a strong correlation between higher folate and vitamin B levels with lower homocysteine levels in the zinc group.
These findings suggest that zinc supplementation can have positive effects on certain nutritional markers in menopausal women. However, we emphasize the need for further research with larger sample sizes and refined dosing to validate and expand upon our results.
After analyzing the results, we found that those who took zinc showed significantly higher folate levels compared to their baseline measurements. Additionally, we observed a noteworthy decrease in homocysteine levels when comparing the two groups after the intervention. Interestingly, we also noted a strong correlation between higher folate and vitamin B levels with lower homocysteine levels in the zinc group.
These findings suggest that zinc supplementation can have positive effects on certain nutritional markers in menopausal women. However, we emphasize the need for further research with larger sample sizes and refined dosing to validate and expand upon our results.
7
We investigated the effects of dietary zinc on obesity related to menopause, particularly in female mice that underwent ovariectomy (Ovx). Our findings revealed that excess zinc led to significant weight gain and symptoms resembling Cushing's syndrome, even though these mice did not consume more food.
The accumulation of zinc in the adrenal glands played a crucial role by interfering with steroid production. This is particularly important since, in Ovx mice, adrenal steroids are the only source of estrogen. The lack of estrogen triggered adrenal hyperplasia and an increase in glucocorticoids, which contributed to the development of Cushing's-like symptoms.
Interestingly, our results showed that supplementing with adrenal steroids could counteract the negative impacts of excess zinc. We also found a positive correlation between plasma zinc levels and cortisol while noting a negative correlation with adrenal steroids and estrogen levels in overweight postmenopausal women.
These insights suggest that it may be beneficial for postmenopausal women to avoid high dietary zinc and consider adrenal steroid supplementation to help manage obesity effectively.
The accumulation of zinc in the adrenal glands played a crucial role by interfering with steroid production. This is particularly important since, in Ovx mice, adrenal steroids are the only source of estrogen. The lack of estrogen triggered adrenal hyperplasia and an increase in glucocorticoids, which contributed to the development of Cushing's-like symptoms.
Interestingly, our results showed that supplementing with adrenal steroids could counteract the negative impacts of excess zinc. We also found a positive correlation between plasma zinc levels and cortisol while noting a negative correlation with adrenal steroids and estrogen levels in overweight postmenopausal women.
These insights suggest that it may be beneficial for postmenopausal women to avoid high dietary zinc and consider adrenal steroid supplementation to help manage obesity effectively.
References
- Zhao Y, Wang Y, Hu L, Chen H, Xiao X, et al. Excess dietary zinc drives a Cushing's-like syndrome in ovariectomized mice - Implications for postmenopausal obesity. Biochem Biophys Res Commun. 2022;630:101. doi:10.1016/j.bbrc.2022.09.042
- Vázquez-Lorente H, Molina-López J, Herrera-Quintana L, Gamarra-Morales Y, Quintero-Osso B, et al. Erythrocyte Zn concentration and antioxidant response after supplementation with Zn in a postmenopausal population. A double-blind randomized trial. Exp Gerontol. 2022;162:111766. doi:10.1016/j.exger.2022.111766
- Vázquez-Lorente H, Herrera-Quintana L, Molina-López J, Gamarra Y, Planells E. Effect of zinc supplementation on circulating concentrations of homocysteine, vitamin B, and folate in a postmenopausal population. J Trace Elem Med Biol. 2022;71:126942. doi:10.1016/j.jtemb.2022.126942
- Vázquez-Lorente H, Molina-López J, Herrera-Quintana L, Gamarra-Morales Y, López-González B, et al. Effectiveness of eight-week zinc supplementation on vitamin D status and leptin levels in a population of postmenopausal women: a double-blind randomized trial. J Trace Elem Med Biol. 2021;65:126730. doi:10.1016/j.jtemb.2021.126730
- Csikós A, Kozma B, Pór Á, Kovács I, Lampé R, et al. Zinc Transporter 9 (SLC30A9) Expression Is Decreased in the Vaginal Tissues of Menopausal Women. Biol Trace Elem Res. 2021;199:4011. doi:10.1007/s12011-020-02525-w
- Damjanovich P, Sipos AG, Larson K, Cunningham TD, Takacs P, et al. Cervicovaginal lavage fluid zinc level as a marker of vaginal atrophy. Menopause. 2020;27:776. doi:10.1097/GME.0000000000001536
- Takacs P, Kozma B, Erdodi B, Jakab A, Larson K, et al. Zinc-containing Vaginal Moisturizer Gel Improves Postmenopausal Vulvovaginal Symptoms: A Pilot Study. J Menopausal Med. 2019;25:63. doi:10.6118/jmm.2019.25.1.63
