Coenzyme Q10 shows effectiveness against migraines
A Comparative Study on the Efficacy of Coenzyme Q10 and Amitriptyline in the Prophylactic Treatment of Migraine Headaches in Children: A Randomized Controlled Trial.
We investigated the effectiveness of coenzyme Q10 in treating migraines in children, comparing it with the commonly prescribed medication, amitriptyline. Our study involved 72 children, aged 5 to 15, who met the criteria for migraine diagnosis set by the International Headache Society.
Over a three-month period, we observed that coenzyme Q10 had positive therapeutic effects, particularly for those requiring long-term treatment. While amitriptyline provided quicker results, the differences between the two treatments in effectiveness were not significantly noticeable after three months. Both treatments led to improvements in the quality of life for the children involved.
Importantly, we noted that children taking amitriptyline experienced more side effects compared to those receiving coenzyme Q10. This finding positions coenzyme Q10 as a promising option due to its comparable effectiveness and better tolerated adverse effect profile.
Read More
7
Co-Q10 reduces oxidative stress in migraines
The Effects of Coenzyme Q10 Supplementation on Oxidative Status and Lipid Profile in Migraine Patients: A Randomized Double-Blinded Controlled Clinical Trial.
We aimed to understand how Coenzyme Q10 (Co-Q10) could help reduce oxidative stress and improve cholesterol levels in individuals suffering from migraines. This involved a well-structured clinical trial with 84 female participants, all diagnosed with episodic migraines. For a period of 12 weeks, half of the participants took a daily dose of Co-Q10, while the other half received a placebo.
After the trial, we discovered some interesting findings. The group that received Co-Q10 showed a significant reduction in levels of malondialdehyde (MDA), a marker related to oxidative stress, compared to the placebo group. However, Co-Q10 did not significantly impact overall antioxidant capacity.
In terms of cholesterol, those taking Co-Q10 experienced an increase in high-density lipoprotein cholesterol (HDL-C), known as the "good" cholesterol. They also had a notable reduction in body fat percentage. Nevertheless, other cholesterol levels and triglycerides did not show significant changes.
Overall, our results suggest that Co-Q10 supplementation can improve certain features associated with migraines, particularly oxidative stress and some lipid profiles. However, it appears that the effects are specific, and not all lipid parameters were influenced.
Read More
8
Coenzyme Q10 aids migraine relief
Practical supplements for prevention and management of migraine attacks: a narrative review.
We explored how coenzyme Q10 could potentially help alleviate headaches, particularly for those suffering from migraines. This study painted a detailed picture of migraine's link to nutritional deficiencies, particularly the role of vital nutrients in reducing the frequency and intensity of migraine attacks.
Coenzyme Q10 emerged as a noteworthy option due to its involvement in mitochondrial function and energy metabolism within the brain. By addressing oxidative stress and inflammation—two key contributors to migraines—this supplement shows promise for bringing relief to those who struggle with frequent headaches.
Alongside coenzyme Q10, other supplements like riboflavin, omega-3 fatty acids, and magnesium were also noted for their positive effects. However, the research highlights the need for more in-depth studies to fully understand how these nutrients impact headache sufferers.
Overall, coenzyme Q10 is one among several promising supplements that could form part of a well-rounded approach to migraine management.
Read More
Most Useful Reviews
10
No side effects
5 people found this helpful
I’ve used this product for several years as a statin alternative. It effectively reduces cholesterol without side effects, unlike the statins that caused me headaches, tremors, and stomach upsets. Though it works slowly, I highly recommend it for those wishing to lower cholesterol naturally.
Read More
9
Headache relief
5 people found this helpful
I had two health check-ups within three months. My cholesterol metabolism was poor, with a total of 279mg in my first blood test. After taking this red yeast rice for one month, my total cholesterol dropped to 224mg, and remarkably, the headache has disappeared. I will continue to take one pill daily to maintain my health and will keep buying it.
Read More
9
Improved condition
1 people found this helpful
I took red rice and nattokinase as my cholesterol was high. Now, my pressure is 110/70. Although I have not measured my cholesterol yet, my general condition has improved significantly. The headache has vanished, and I consider this a good product.
We engaged in a study that aimed to explore the impact of Coenzyme Q10 when combined with L-carnitine on migraine symptoms. Our research involved 56 participants aged between 20 and 40 years, all experiencing migraine headaches. They were randomly divided into two groups: one received daily doses of 30 mg of Coenzyme Q10 and 500 mg of L-carnitine, while the other group got placebo tablets.
Over an 8-week period, we gathered data on the severity, duration, frequency of headache attacks, and even checked levels of lactate—a marker of mitochondrial metabolism. By the end of the study, we observed significant improvements across the board. Participants reported reductions in headache severity, duration, frequency, and lactate levels, highlighting the potential of these supplements in alleviating migraine symptoms.
The findings suggest that this combination therapy could be beneficial for those struggling with migraine headaches. This study not only provides evidence of the positive effects of Coenzyme Q10 and L-carnitine but also opens the door for further exploration into their use in headache management strategies.
Read More
9
Nonprescription therapies reduce VM symptoms
Effects of nonprescription therapies on vestibular migraine: a questionnaire-based observational study.
We assessed how nonprescription therapies, including coenzyme Q10, affect headaches related to vestibular migraine (VM). In a detailed study conducted over two years with participants diagnosed with VM, we encouraged patients to optimize their lifestyle through proper sleep, hydration, exercise, and nutrition.
Among the treatments, a combination product featuring riboflavin, magnesium, coenzyme Q10, and feverfew was used. After three months of treatment, our findings showed a notable reduction in symptoms. Specifically, measures of dizziness and severity of vertigo were significantly improved for many participants.
About half of the patients reported a positive change in their symptoms, suggesting that the combination's components—including coenzyme Q10—may help alleviate headache severity associated with VM. However, it's essential to remember that we cannot determine the specific impact of coenzyme Q10 alone due to its inclusion with other therapies.
Overall, this study offers encouraging preliminary evidence that nonprescription options can provide relief for VM sufferers, making it a vital area for further investigation.
Read More
9
CoQ10 aids migraine prevention
Review on Headache Related to Dietary Supplements.
We delved into the role of Coenzyme Q10 (CoQ10) in managing headache symptoms, particularly migraines. This exploration stemmed from the understanding that migraines are complex and may be influenced by various factors, including energy deficits in the brain.
CoQ10 is recognized for its function in boosting mitochondrial energy metabolism, which is seen as a potential avenue for alleviating headaches. We learned that certain nutrients, including CoQ10, have shown promise in reducing the frequency and severity of migraine attacks. In fact, studies reported significant reductions in headache occurrences when individuals incorporated CoQ10 into their regimen.
While we found evidence supporting CoQ10's effectiveness, it's important to note that it’s often studied alongside other supplements. This means that while CoQ10 may play a beneficial role, it's challenging to pinpoint its isolated effects definitively. Nevertheless, the insights from the research suggest that adding CoQ10 to our preventive strategies for migraines could be a worthy consideration.
Read More
9
Combined supplement shows promise
Open Label Prospective Experience of Supplementation with a Fixed Combination of Magnesium, Vitamin B2, Feverfew, Andrographis Paniculata and Coenzyme Q10 for Episodic Migraine Prophylaxis.
We explored the use of a dietary supplement combining magnesium, vitamin B2, feverfew, andrographis paniculata, and coenzyme Q10 to prevent episodic migraines. This pilot study involved 113 patients in Greece who followed the treatment for three months after a one-month baseline period.
Our main focus was on how this supplementation affected the number of migraine days each month. We also tracked changes in pain intensity, the use of acute medications for migraines, and the overall quality of life through various assessment tools.
The results indicated that the combination supplement, including coenzyme Q10, seemed effective in reducing monthly migraine days. However, since this was a single-arm study without a control group, we can't pinpoint the specific contribution of coenzyme Q10 alone. A randomized, placebo-controlled trial would be essential to confirm these promising findings and clarify the role of each component in the mix.
Read More
9
Nutraceuticals aid pediatric headaches
Complementary and alternative medicine (CAM) in headache of children and adolescents: open-label Italian study.
We evaluated how effectively Coenzyme Q10, along with several other nutraceuticals, can help in preventing headaches in children and adolescents. The study involved 99 children aged 6 to 17 who were experiencing primary headaches. Over a period of 12 months, we monitored their headache frequency and the need for pain relief medications both before and after treatment.
Among the different treatments we used, Coenzyme Q10 was included in a combination called compound n°3, alongside magnesium oxide, Partenium, and Vitamin B2. Our findings showed that all three treatment compounds significantly reduced headache frequency and the reliance on pain relief medications. However, Coenzyme Q10’s effectiveness varied; it was found to be less effective than other combinations for certain types of headaches.
Overall, we found that nutraceuticals like Coenzyme Q10 are generally well-received by both parents and children and they seem to provide a promising alternative in headache management. While not every combination showed uniform effectiveness, our research supports the potential of these supplements in making headaches more manageable for children.
I’ve used this product for several years as a statin alternative. It effectively reduces cholesterol without side effects, unlike the statins that caused me headaches, tremors, and stomach upsets. Though it works slowly, I highly recommend it for those wishing to lower cholesterol naturally.
Read More
9
Headache relief
5 people found this helpful
I had two health check-ups within three months. My cholesterol metabolism was poor, with a total of 279mg in my first blood test. After taking this red yeast rice for one month, my total cholesterol dropped to 224mg, and remarkably, the headache has disappeared. I will continue to take one pill daily to maintain my health and will keep buying it.
Read More
9
Improved condition
1 people found this helpful
I took red rice and nattokinase as my cholesterol was high. Now, my pressure is 110/70. Although I have not measured my cholesterol yet, my general condition has improved significantly. The headache has vanished, and I consider this a good product.
Read More
0
Headache issue
1 people found this helpful
Not for me. It's acceptable but it gives me headaches and dries out my sinuses. It took me over a month to figure out this supplement was the cause. I don't know if it worked on my cholesterol numbers or not - haven't received the results.
Read More
9
Noticeable improvement
I gave this to my mother to lower her blood lipids. I'm pleased to note that her headaches have improved. I will provide updates on her blood lipid levels after a follow-up test.
A headache is a common condition characterized by pain or discomfort in the head, scalp, or neck. It can vary in intensity, frequency, and duration, and is often classified into two primary categories: primary and secondary headaches. Primary headaches, such as tension-type headaches, migraines, and cluster headaches, are not caused by other medical conditions. Instead, they are conditions in themselves, often resulting from factors like stress, hormonal changes, or environmental triggers. Secondary headaches, on the other hand, are symptoms of an underlying issue, such as an infection, injury, or other medical conditions.
The experience of a headache can differ widely among individuals. Depending on the type, headaches can be throbbing or constant and may be accompanied by other symptoms like nausea, sensitivity to light, or aura effects before the headache strikes. Effective management strategies vary by headache type and may include over-the-counter pain relievers, lifestyle changes, and in some cases, prescription medications. Understanding the specific triggers and patterns related to your headaches can be crucial for prevention and treatment, so maintaining a headache diary may be beneficial for those experiencing frequent or severe episodes.
Red yeast rice is a traditional Chinese food and herbal supplement made by fermenting rice with a specific type of mold called Monascus purpureus. This fermentation process gives the rice its distinctive red color, as well as its potential health benefits. Historically, it has been used in Asian cuisine as a coloring agent and flavor enhancer, but it has gained popularity in the wellness community mainly for its cholesterol-lowering effects. The active compounds in red yeast rice include monacolins, particularly monacolin K, which is chemically similar to the active ingredient in statin medications used to manage cholesterol levels.
Numerous studies suggest that red yeast rice may effectively reduce total cholesterol and LDL (commonly referred to as "bad" cholesterol) levels. However, results can vary based on the dosage and specific product formulation, as the amount of active compounds in supplements can differ significantly. As with any supplement, it’s essential to consult with a healthcare professional before adding red yeast rice to your regimen, especially for individuals with existing health conditions or those taking medication, as it may interact with other treatments. Overall, while red yeast rice could offer benefits for heart health, it should be approached with consideration and care.
Based on user reviews, individuals typically report seeing results for headaches within a one to three-month timeframe after starting supplementation. One user noted that after just one month of taking red yeast rice, their headache had disappeared alongside improvements to their cholesterol levels Read Review. Another review indicated that consistent use was necessary, with some users experiencing gradual headaches relief over the course of years Read Review.
Furthermore, several users shared that headaches resolved alongside other health improvements, with one stating that their headaches vanished as their general condition significantly improved Read Review. Another review attributed the lack of headache to consistent usage of a different supplement for blood pressure and circulation Read Review. Overall, while immediate relief may be possible for some, many users emphasize the importance of consistent long-term use for optimal results.
Coenzyme Q10 (CoQ10) has garnered attention as a potential supplement for headache relief, particularly in the context of migraines. Multiple studies suggest that CoQ10 may help reduce the frequency and intensity of migraine attacks. For instance, a well-structured clinical trial indicated that participants taking CoQ10 showed significant reductions in oxidative stress markers associated with migraines, as well as improvements in specific lipid profiles, which are known to be linked to headache management [5]. Additionally, a review highlighted CoQ10’s role in energy metabolism within the brain, suggesting that its antioxidant properties could play a beneficial role in alleviating migraine discomfort [3].
While the existing research presents encouraging findings, it is essential to note that most studies evaluate CoQ10 in combination with other supplements, which complicates the isolation of its specific effects [6]. Furthermore, the evidence supporting CoQ10 is classified as Level C, indicating that more rigorous clinical trials are necessary to thoroughly understand its efficacy [1]. Overall, CoQ10 appears to be a promising option for individuals suffering from headaches, but one should approach its use cautiously and consider it as potentially part of a broader treatment strategy rather than a standalone solution.
Users generally report significant improvements in symptoms after using red yeast rice and other supplements, particularly in relation to headaches and cholesterol levels. Several individuals have shared experiences of headache relief coinciding with their cholesterol management. For instance, one user noted that after just one month of taking red yeast rice, their headache completely disappeared alongside a considerable reduction in cholesterol levels from 279mg to 224mg Read Review. Another user, who had been using the product for several years, reported that they found it to effectively lower cholesterol without the side effects commonly associated with traditional statins, thereby avoiding headaches that they previously experienced Read Review.
Additionally, other users also noted that their headaches improved significantly. One reviewer mentioned that their headaches vanished as their overall health condition improved, reaffirming the positive benefits of this supplement in conjunction with others Read Review. Another user highlighted the positive results for their mother, who experienced fewer headaches after taking the supplement, and they plan to evaluate her blood lipid levels after further testing Read Review. While these results are encouraging, it is essential to keep in mind that individual results may vary.
Users report positive experiences when combining red yeast rice with other supplements for managing headaches. Several individuals noted that their headaches diminished significantly alongside improvements in cholesterol levels and overall health. For instance, one user highlighted that after taking red yeast rice for a month, they no longer experienced headaches as their cholesterol dropped considerably Read Review. Another user, who combined red yeast rice with nattokinase, mentioned that their headache vanished as their blood pressure normalized Read Review.
Furthermore, one review suggested that headaches improved significantly for a user’s mother after starting the supplement aimed at lowering blood lipids Read Review. Another individual reported that a different supplement for blood pressure and circulation led to the disappearance of their headaches as well Read Review. Overall, users seem to emphasize the interplay between these supplements in achieving relief from headaches, alongside other health benefits.
Users report varying experiences regarding the effectiveness of Red Yeast Rice for treating headaches, with many indicating positive results. For instance, one user noted that after a month of taking a single pill daily, their headache disappeared alongside a significant drop in total cholesterol levels from 279mg to 224mg Read Review. Another review mentions that headaches that were initially caused by statin medications were alleviated after switching to Red Yeast Rice, indicating its potential as a gentler alternative for cholesterol management Read Review.
Additionally, users reported improvements in their overall condition alongside headache relief. One reviewer highlighted that their headaches vanished after starting Red Yeast Rice in conjunction with another supplement, suggesting a comprehensive impact on well-being Read Review. Similarly, another user observed improvement in their mother's headaches after incorporating Red Yeast Rice into her routine to lower blood lipids Read Review. Overall, while individual responses may vary, many users found that taking Red Yeast Rice—often at a dosage of one pill daily—has contributed to both lowered cholesterol and headache relief.
9
Headache relief
5 people found this helpful
I had two health check-ups within three months. My cholesterol metabolism was poor, with a total of 279mg in my first blood test. After taking this red yeast rice for one month, my total cholesterol dropped to 224mg, and remarkably, the headache has disappeared. I will continue to take one pill daily to maintain my health and will keep buying it.
10
No side effects
5 people found this helpful
I’ve used this product for several years as a statin alternative. It effectively reduces cholesterol without side effects, unlike the statins that caused me headaches, tremors, and stomach upsets. Though it works slowly, I highly recommend it for those wishing to lower cholesterol naturally.
9
Improved condition
1 people found this helpful
I took red rice and nattokinase as my cholesterol was high. Now, my pressure is 110/70. Although I have not measured my cholesterol yet, my general condition has improved significantly. The headache has vanished, and I consider this a good product.
9
Headache gone
I take hongguk for blood pressure and blood circulation, and after consistent consumption, my headache has definitely disappeared.
9
Noticeable improvement
I gave this to my mother to lower her blood lipids. I'm pleased to note that her headaches have improved. I will provide updates on her blood lipid levels after a follow-up test.
7
Co-Q10 reduces oxidative stress in migraines
The Effects of Coenzyme Q10 Supplementation on Oxidative Status and Lipid Profile in Migraine Patients: A Randomized Double-Blinded Controlled Clinical Trial.
We aimed to understand how Coenzyme Q10 (Co-Q10) could help reduce oxidative stress and improve cholesterol levels in individuals suffering from migraines. This involved a well-structured clinical trial with 84 female participants, all diagnosed with episodic migraines. For a period of 12 weeks, half of the participants took a daily dose of Co-Q10, while the other half received a placebo.
After the trial, we discovered some interesting findings. The group that received Co-Q10 showed a significant reduction in levels of malondialdehyde (MDA), a marker related to oxidative stress, compared to the placebo group. However, Co-Q10 did not significantly impact overall antioxidant capacity.
In terms of cholesterol, those taking Co-Q10 experienced an increase in high-density lipoprotein cholesterol (HDL-C), known as the "good" cholesterol. They also had a notable reduction in body fat percentage. Nevertheless, other cholesterol levels and triglycerides did not show significant changes.
Overall, our results suggest that Co-Q10 supplementation can improve certain features associated with migraines, particularly oxidative stress and some lipid profiles. However, it appears that the effects are specific, and not all lipid parameters were influenced.
8
Coenzyme Q10 aids migraine relief
Practical supplements for prevention and management of migraine attacks: a narrative review.
We explored how coenzyme Q10 could potentially help alleviate headaches, particularly for those suffering from migraines. This study painted a detailed picture of migraine's link to nutritional deficiencies, particularly the role of vital nutrients in reducing the frequency and intensity of migraine attacks.
Coenzyme Q10 emerged as a noteworthy option due to its involvement in mitochondrial function and energy metabolism within the brain. By addressing oxidative stress and inflammation—two key contributors to migraines—this supplement shows promise for bringing relief to those who struggle with frequent headaches.
Alongside coenzyme Q10, other supplements like riboflavin, omega-3 fatty acids, and magnesium were also noted for their positive effects. However, the research highlights the need for more in-depth studies to fully understand how these nutrients impact headache sufferers.
Overall, coenzyme Q10 is one among several promising supplements that could form part of a well-rounded approach to migraine management.
7
Coenzyme Q10 may reduce headaches
[Complementary and supplementary procedures in the treatment of headache].
We explored the impact of coenzyme Q10 in treating headaches, particularly in children and adolescents. The review highlighted various complementary therapies for primary headaches and indicated that coenzyme Q10, along with other dietary supplements like riboflavin, magnesium, and vitamin D, may offer some benefits.
While evidence suggests that coenzyme Q10 could aid in reducing headaches, it’s important to understand that it was evaluated alongside other treatments. This means the exact contribution of coenzyme Q10 on its own might be less clear. We noted that patients experiencing headaches often turn to complementary therapies due to a perceived lack of adequate medical care.
Overall, our findings suggest that coenzyme Q10 could be a part of a broader strategy to manage headaches. Its potential effectiveness highlights the need for more in-depth studies to isolate its benefits and understand how it fits into headache treatment plans.
7
Coenzyme Q10 shows potential benefits
Nutraceuticals and Headache 2024: Riboflavin, Coenzyme Q10, Feverfew, Magnesium, Melatonin, and Butterbur.
We observed that coenzyme Q10 may have potential benefits for individuals suffering from headaches, specifically migraines. Although the evidence for its effectiveness is categorized as Level C, suggesting that it has not undergone extensive testing, the preliminary outcomes show a low rate of adverse events associated with its use.
While we acknowledge that the available studies do not provide definitive conclusions, this antioxidant has been noted for its role in energy production and mitochondrial function, which may be responsible for its positive effects on migraine prevention. However, we recognize the need for more rigorous clinical trials to better establish its efficacy before making broad recommendations.
In summary, coenzyme Q10 appears to offer a promising avenue for headache relief, but it is crucial to approach its use with caution until more conclusive evidence is available.
References
Tepper SJ, Tepper K. Nutraceuticals and Headache 2024: Riboflavin, Coenzyme Q10, Feverfew, Magnesium, Melatonin, and Butterbur. Curr Pain Headache Rep. 2025;29:33. doi:10.1007/s11916-025-01358-3
Tavasoli A, Rezazadeh M, Kachuei M. Eyebrow bleeding as a rare migraine symptom: a case report. Ann Med Surg (Lond). 2024;86:7377. doi:10.1097/MS9.0000000000002655
Hajhashemy Z, Golpour-Hamedani S, Eshaghian N, Sadeghi O, Khorvash F, et al. Practical supplements for prevention and management of migraine attacks: a narrative review. Front Nutr. 2024;11:1433390. doi:10.3389/fnut.2024.1433390
Hannigan IP, Rosengren SM, Di Tanna GL, Watson SRD, Welgampola MS. Effects of nonprescription therapies on vestibular migraine: a questionnaire-based observational study. Intern Med J. 2024;54:916. doi:10.1111/imj.16314
Dahri M, Sarafan Sadeghi A, Pahlavani N, Nattagh-Eshtivani E, Hashemilar M, et al. The Effects of Coenzyme Q10 Supplementation on Oxidative Status and Lipid Profile in Migraine Patients: A Randomized Double-Blinded Controlled Clinical Trial. Clin Nutr Res. 2023;12:257. doi:10.7762/cnr.2023.12.4.257
Gaul C, Zaranek L, Goßrau G. [Complementary and supplementary procedures in the treatment of headache]. Schmerz. 2023;37:448. doi:10.1007/s00482-023-00738-1
Yaghini O, Hoseini N, Ghazavi MR, Mansouri V, Nasiri J, et al. A Comparative Study on the Efficacy of Coenzyme Q10 and Amitriptyline in the Prophylactic Treatment of Migraine Headaches in Children: A Randomized Controlled Trial. Adv Biomed Res. 2022;11:43. doi:10.4103/abr.abr_235_20
Quintana S, Russo M, Torelli P. Nutraceuticals and migraine: further strategy for the treatment of specific conditions. Neurol Sci. 2022;43:6565. doi:10.1007/s10072-022-06250-1
Ariyanfar S, Razeghi Jahromi S, Togha M, Ghorbani Z. Review on Headache Related to Dietary Supplements. Curr Pain Headache Rep. 2022;26:193. doi:10.1007/s11916-022-01019-9
Kaur K, Hernandez V, Al Hajaj SW, Ebrahim AM, Razack M, et al. The Efficacy of Herbal Supplements and Nutraceuticals for Prevention of Migraine: Can They Help?. Cureus. 2021;13:e14868. doi:10.7759/cureus.14868
Sazali S, Badrin S, Norhayati MN, Idris NS. Coenzyme Q10 supplementation for prophylaxis in adult patients with migraine-a meta-analysis. BMJ Open. 2021;11:e039358. doi:10.1136/bmjopen-2020-039358
Vikelis M, Dermitzakis EV, Vlachos GS, Soldatos P, Spingos KC, et al. Open Label Prospective Experience of Supplementation with a Fixed Combination of Magnesium, Vitamin B2, Feverfew, Andrographis Paniculata and Coenzyme Q10 for Episodic Migraine Prophylaxis. J Clin Med. 2020;10. doi:10.3390/jcm10010067
Onofri A, Necozione S, Tozzi E. Complementary and alternative medicine (CAM) in headache of children and adolescents: open-label Italian study. Clin Ter. 2020;171:e393. doi:10.7417/CT.2020.2246
Lisicki M, Schoenen J. Metabolic treatments of migraine. Expert Rev Neurother. 2020;20:295. doi:10.1080/14737175.2020.1729130
Moscano F, Guiducci M, Maltoni L, Striano P, Ledda MG, et al. An observational study of fixed-dose Tanacetum parthenium nutraceutical preparation for prophylaxis of pediatric headache. Ital J Pediatr. 2019;45:36. doi:10.1186/s13052-019-0624-z
Hajihashemi P, Askari G, Khorvash F, Reza Maracy M, Nourian M. The effects of concurrent Coenzyme Q10, L-carnitine supplementation in migraine prophylaxis: A randomized, placebo-controlled, double-blind trial. Cephalalgia. 2019;39:648. doi:10.1177/0333102418821661