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SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.1
USERS' SCORE
Good
Based on 6 Reviews
8.4
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Red Yeast Rice (Monascus purpureus)
1,200 mg
†
Coenzyme Q10 (Ubiquinone)
100 mg
†
Top Medical Research Studies
8
Coenzyme Q10 shows effectiveness against migraines
A Comparative Study on the Efficacy of Coenzyme Q10 and Amitriptyline in the Prophylactic Treatment of Migraine Headaches in Children: A Randomized Controlled Trial.
Directly compares two treatments
We investigated the effectiveness of coenzyme Q10 in treating migraines in children, comparing it with the commonly prescribed medication, amitriptyline. Our study involved 72 children, aged 5 to 15, who met the criteria for migraine diagnosis set by the International Headache Society.
Over a three-month period, we observed that coenzyme Q10 had positive therapeutic effects, particularly for those requiring long-term treatment. While amitriptyline provided quicker results, the differences between the two treatments in effectiveness were not significantly noticeable after three months. Both treatments led to improvements in the quality of life for the children involved.
Importantly, we noted that children taking amitriptyline experienced more side effects compared to those receiving coenzyme Q10. This finding positions coenzyme Q10 as a promising option due to its comparable effectiveness and better tolerated adverse effect profile.
Over a three-month period, we observed that coenzyme Q10 had positive therapeutic effects, particularly for those requiring long-term treatment. While amitriptyline provided quicker results, the differences between the two treatments in effectiveness were not significantly noticeable after three months. Both treatments led to improvements in the quality of life for the children involved.
Importantly, we noted that children taking amitriptyline experienced more side effects compared to those receiving coenzyme Q10. This finding positions coenzyme Q10 as a promising option due to its comparable effectiveness and better tolerated adverse effect profile.
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7
Co-Q10 reduces oxidative stress in migraines
The Effects of Coenzyme Q10 Supplementation on Oxidative Status and Lipid Profile in Migraine Patients: A Randomized Double-Blinded Controlled Clinical Trial.
Directly investigates Co-Q10 effects
We aimed to understand how Coenzyme Q10 (Co-Q10) could help reduce oxidative stress and improve cholesterol levels in individuals suffering from migraines. This involved a well-structured clinical trial with 84 female participants, all diagnosed with episodic migraines. For a period of 12 weeks, half of the participants took a daily dose of Co-Q10, while the other half received a placebo.
After the trial, we discovered some interesting findings. The group that received Co-Q10 showed a significant reduction in levels of malondialdehyde (MDA), a marker related to oxidative stress, compared to the placebo group. However, Co-Q10 did not significantly impact overall antioxidant capacity.
In terms of cholesterol, those taking Co-Q10 experienced an increase in high-density lipoprotein cholesterol (HDL-C), known as the "good" cholesterol. They also had a notable reduction in body fat percentage. Nevertheless, other cholesterol levels and triglycerides did not show significant changes.
Overall, our results suggest that Co-Q10 supplementation can improve certain features associated with migraines, particularly oxidative stress and some lipid profiles. However, it appears that the effects are specific, and not all lipid parameters were influenced.
After the trial, we discovered some interesting findings. The group that received Co-Q10 showed a significant reduction in levels of malondialdehyde (MDA), a marker related to oxidative stress, compared to the placebo group. However, Co-Q10 did not significantly impact overall antioxidant capacity.
In terms of cholesterol, those taking Co-Q10 experienced an increase in high-density lipoprotein cholesterol (HDL-C), known as the "good" cholesterol. They also had a notable reduction in body fat percentage. Nevertheless, other cholesterol levels and triglycerides did not show significant changes.
Overall, our results suggest that Co-Q10 supplementation can improve certain features associated with migraines, particularly oxidative stress and some lipid profiles. However, it appears that the effects are specific, and not all lipid parameters were influenced.
Read More
8
Coenzyme Q10 aids migraine relief
Practical supplements for prevention and management of migraine attacks: a narrative review.
Addresses coenzyme Q10 effectiveness
We explored how coenzyme Q10 could potentially help alleviate headaches, particularly for those suffering from migraines. This study painted a detailed picture of migraine's link to nutritional deficiencies, particularly the role of vital nutrients in reducing the frequency and intensity of migraine attacks.
Coenzyme Q10 emerged as a noteworthy option due to its involvement in mitochondrial function and energy metabolism within the brain. By addressing oxidative stress and inflammation—two key contributors to migraines—this supplement shows promise for bringing relief to those who struggle with frequent headaches.
Alongside coenzyme Q10, other supplements like riboflavin, omega-3 fatty acids, and magnesium were also noted for their positive effects. However, the research highlights the need for more in-depth studies to fully understand how these nutrients impact headache sufferers.
Overall, coenzyme Q10 is one among several promising supplements that could form part of a well-rounded approach to migraine management.
Coenzyme Q10 emerged as a noteworthy option due to its involvement in mitochondrial function and energy metabolism within the brain. By addressing oxidative stress and inflammation—two key contributors to migraines—this supplement shows promise for bringing relief to those who struggle with frequent headaches.
Alongside coenzyme Q10, other supplements like riboflavin, omega-3 fatty acids, and magnesium were also noted for their positive effects. However, the research highlights the need for more in-depth studies to fully understand how these nutrients impact headache sufferers.
Overall, coenzyme Q10 is one among several promising supplements that could form part of a well-rounded approach to migraine management.
Read More
Most Useful Reviews
9.5
Headache relief
I had two health check-ups within three months. My cholesterol metabolism was poor, with a total of 279mg in my first blood test. After taking this red yeast rice for one month, my total cholesterol dropped to 224mg, and remarkably, the headache has disappeared. I will continue to take one pill daily to maintain my health and will keep buying it.
Read More
8.8
No side effects
I’ve used this product for several years as a statin alternative. It effectively reduces cholesterol without side effects, unlike the statins that caused me headaches, tremors, and stomach upsets. Though it works slowly, I highly recommend it for those wishing to lower cholesterol naturally.
Read More
9.5
Improved condition
I took red rice and nattokinase as my cholesterol was high. Now, my pressure is 110/70. Although I have not measured my cholesterol yet, my general condition has improved significantly. The headache has vanished, and I consider this a good product.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 16 Researches
8.1
9.5
Coenzyme Q10 reduces migraine symptoms
The effects of concurrent Coenzyme Q10, L-carnitine supplementation in migraine prophylaxis: A randomized, placebo-controlled, double-blind trial.
Combination effects complicate isolated analysis
We engaged in a study that aimed to explore the impact of Coenzyme Q10 when combined with L-carnitine on migraine symptoms. Our research involved 56 participants aged between 20 and 40 years, all experiencing migraine headaches. They were randomly divided into two groups: one received daily doses of 30 mg of Coenzyme Q10 and 500 mg of L-carnitine, while the other group got placebo tablets.
Over an 8-week period, we gathered data on the severity, duration, frequency of headache attacks, and even checked levels of lactate—a marker of mitochondrial metabolism. By the end of the study, we observed significant improvements across the board. Participants reported reductions in headache severity, duration, frequency, and lactate levels, highlighting the potential of these supplements in alleviating migraine symptoms.
The findings suggest that this combination therapy could be beneficial for those struggling with migraine headaches. This study not only provides evidence of the positive effects of Coenzyme Q10 and L-carnitine but also opens the door for further exploration into their use in headache management strategies.
Over an 8-week period, we gathered data on the severity, duration, frequency of headache attacks, and even checked levels of lactate—a marker of mitochondrial metabolism. By the end of the study, we observed significant improvements across the board. Participants reported reductions in headache severity, duration, frequency, and lactate levels, highlighting the potential of these supplements in alleviating migraine symptoms.
The findings suggest that this combination therapy could be beneficial for those struggling with migraine headaches. This study not only provides evidence of the positive effects of Coenzyme Q10 and L-carnitine but also opens the door for further exploration into their use in headache management strategies.
Read More
9
Nonprescription therapies reduce VM symptoms
Effects of nonprescription therapies on vestibular migraine: a questionnaire-based observational study.
Mixed results on coenzyme Q10
We assessed how nonprescription therapies, including coenzyme Q10, affect headaches related to vestibular migraine (VM). In a detailed study conducted over two years with participants diagnosed with VM, we encouraged patients to optimize their lifestyle through proper sleep, hydration, exercise, and nutrition.
Among the treatments, a combination product featuring riboflavin, magnesium, coenzyme Q10, and feverfew was used. After three months of treatment, our findings showed a notable reduction in symptoms. Specifically, measures of dizziness and severity of vertigo were significantly improved for many participants.
About half of the patients reported a positive change in their symptoms, suggesting that the combination's components—including coenzyme Q10—may help alleviate headache severity associated with VM. However, it's essential to remember that we cannot determine the specific impact of coenzyme Q10 alone due to its inclusion with other therapies.
Overall, this study offers encouraging preliminary evidence that nonprescription options can provide relief for VM sufferers, making it a vital area for further investigation.
Among the treatments, a combination product featuring riboflavin, magnesium, coenzyme Q10, and feverfew was used. After three months of treatment, our findings showed a notable reduction in symptoms. Specifically, measures of dizziness and severity of vertigo were significantly improved for many participants.
About half of the patients reported a positive change in their symptoms, suggesting that the combination's components—including coenzyme Q10—may help alleviate headache severity associated with VM. However, it's essential to remember that we cannot determine the specific impact of coenzyme Q10 alone due to its inclusion with other therapies.
Overall, this study offers encouraging preliminary evidence that nonprescription options can provide relief for VM sufferers, making it a vital area for further investigation.
Read More
9
CoQ10 aids migraine prevention
Review on Headache Related to Dietary Supplements.
Partially helpful, needs context
We delved into the role of Coenzyme Q10 (CoQ10) in managing headache symptoms, particularly migraines. This exploration stemmed from the understanding that migraines are complex and may be influenced by various factors, including energy deficits in the brain.
CoQ10 is recognized for its function in boosting mitochondrial energy metabolism, which is seen as a potential avenue for alleviating headaches. We learned that certain nutrients, including CoQ10, have shown promise in reducing the frequency and severity of migraine attacks. In fact, studies reported significant reductions in headache occurrences when individuals incorporated CoQ10 into their regimen.
While we found evidence supporting CoQ10's effectiveness, it's important to note that it’s often studied alongside other supplements. This means that while CoQ10 may play a beneficial role, it's challenging to pinpoint its isolated effects definitively. Nevertheless, the insights from the research suggest that adding CoQ10 to our preventive strategies for migraines could be a worthy consideration.
CoQ10 is recognized for its function in boosting mitochondrial energy metabolism, which is seen as a potential avenue for alleviating headaches. We learned that certain nutrients, including CoQ10, have shown promise in reducing the frequency and severity of migraine attacks. In fact, studies reported significant reductions in headache occurrences when individuals incorporated CoQ10 into their regimen.
While we found evidence supporting CoQ10's effectiveness, it's important to note that it’s often studied alongside other supplements. This means that while CoQ10 may play a beneficial role, it's challenging to pinpoint its isolated effects definitively. Nevertheless, the insights from the research suggest that adding CoQ10 to our preventive strategies for migraines could be a worthy consideration.
Read More
9
Combined supplement shows promise
Open Label Prospective Experience of Supplementation with a Fixed Combination of Magnesium, Vitamin B2, Feverfew, Andrographis Paniculata and Coenzyme Q10 for Episodic Migraine Prophylaxis.
Coenzyme Q10's exact role unclear
We explored the use of a dietary supplement combining magnesium, vitamin B2, feverfew, andrographis paniculata, and coenzyme Q10 to prevent episodic migraines. This pilot study involved 113 patients in Greece who followed the treatment for three months after a one-month baseline period.
Our main focus was on how this supplementation affected the number of migraine days each month. We also tracked changes in pain intensity, the use of acute medications for migraines, and the overall quality of life through various assessment tools.
The results indicated that the combination supplement, including coenzyme Q10, seemed effective in reducing monthly migraine days. However, since this was a single-arm study without a control group, we can't pinpoint the specific contribution of coenzyme Q10 alone. A randomized, placebo-controlled trial would be essential to confirm these promising findings and clarify the role of each component in the mix.
Our main focus was on how this supplementation affected the number of migraine days each month. We also tracked changes in pain intensity, the use of acute medications for migraines, and the overall quality of life through various assessment tools.
The results indicated that the combination supplement, including coenzyme Q10, seemed effective in reducing monthly migraine days. However, since this was a single-arm study without a control group, we can't pinpoint the specific contribution of coenzyme Q10 alone. A randomized, placebo-controlled trial would be essential to confirm these promising findings and clarify the role of each component in the mix.
Read More
9
Nutraceuticals aid pediatric headaches
Complementary and alternative medicine (CAM) in headache of children and adolescents: open-label Italian study.
Study complexity affects clarity
We evaluated how effectively Coenzyme Q10, along with several other nutraceuticals, can help in preventing headaches in children and adolescents. The study involved 99 children aged 6 to 17 who were experiencing primary headaches. Over a period of 12 months, we monitored their headache frequency and the need for pain relief medications both before and after treatment.
Among the different treatments we used, Coenzyme Q10 was included in a combination called compound n°3, alongside magnesium oxide, Partenium, and Vitamin B2. Our findings showed that all three treatment compounds significantly reduced headache frequency and the reliance on pain relief medications. However, Coenzyme Q10’s effectiveness varied; it was found to be less effective than other combinations for certain types of headaches.
Overall, we found that nutraceuticals like Coenzyme Q10 are generally well-received by both parents and children and they seem to provide a promising alternative in headache management. While not every combination showed uniform effectiveness, our research supports the potential of these supplements in making headaches more manageable for children.
Among the different treatments we used, Coenzyme Q10 was included in a combination called compound n°3, alongside magnesium oxide, Partenium, and Vitamin B2. Our findings showed that all three treatment compounds significantly reduced headache frequency and the reliance on pain relief medications. However, Coenzyme Q10’s effectiveness varied; it was found to be less effective than other combinations for certain types of headaches.
Overall, we found that nutraceuticals like Coenzyme Q10 are generally well-received by both parents and children and they seem to provide a promising alternative in headache management. While not every combination showed uniform effectiveness, our research supports the potential of these supplements in making headaches more manageable for children.
Read More
User Reviews
USERS' SCORE
Good
Based on 6 Reviews
8.4
9.5
Headache relief
I had two health check-ups within three months. My cholesterol metabolism was poor, with a total of 279mg in my first blood test. After taking this red yeast rice for one month, my total cholesterol dropped to 224mg, and remarkably, the headache has disappeared. I will continue to take one pill daily to maintain my health and will keep buying it.
Read More
9.5
Improved condition
I took red rice and nattokinase as my cholesterol was high. Now, my pressure is 110/70. Although I have not measured my cholesterol yet, my general condition has improved significantly. The headache has vanished, and I consider this a good product.
9.5
Noticeable improvement
I gave this to my mother to lower her blood lipids. I'm pleased to note that her headaches have improved. I will provide updates on her blood lipid levels after a follow-up test.
8.8
No side effects
I’ve used this product for several years as a statin alternative. It effectively reduces cholesterol without side effects, unlike the statins that caused me headaches, tremors, and stomach upsets. Though it works slowly, I highly recommend it for those wishing to lower cholesterol naturally.
Read More
8.3
Headache gone
I take hongguk for blood pressure and blood circulation, and after consistent consumption, my headache has definitely disappeared.
