We explored the impact of taurine on glial cell health in the retinas of diabetic rats and cell cultures exposed to high glucose. By conducting a thorough analysis, we found that taurine treatment significantly reduced cell death compared to untreated diabetic counterparts.
Over 8 and 12 weeks, we observed virtually no harmful cell changes in taurine-treated groups. Additionally, when retinal cells were exposed to high glucose conditions, taurine effectively reduced apoptosis across various concentrations. This suggests that taurine not only protects against cell death but also boosts the expression of a crucial taurine transporter in diabetic conditions.
Read More
9
N-acetyltaurine impacts obesity control
PTER is a N-acetyltaurine hydrolase that regulates feeding and obesity.
We investigated the connection between taurine metabolites and their impact on feeding behavior and obesity, focusing specifically on a compound called N-acetyltaurine. Our findings revealed that N-acetyltaurine's levels in the body are influenced by various factors, including diet and exercise. One key player in the metabolism of this compound is an enzyme known as phosphotriesterase-related (PTER).
PTER serves as a crucial hydrolase, breaking down N-acetyltaurine into taurine and acetate. We discovered that when PTER is genetically removed in mice, there's a noticeable increase in N-acetyltaurine levels. This change dramatically affects the creatures' dietary habits and weight management, as these knockout mice showed reduced food intake and resented gaining weight, even when offered a high-calorie diet.
Additionally, administering N-acetyltaurine to healthy mice led to a reduction in their food consumption and overall body weight. These findings tie PTER and N-acetyltaurine into the larger narrative of how taurine influences energy balance and weight control, making them significant to understanding our metabolism and the management of obesity.
Read More
9
Taurine aids spinal cord recovery
Improvement of diabetes-induced spinal cord axon injury with taurine via nerve growth factor-dependent Akt/mTOR pathway.
We explored the impact of taurine on spinal cord axon injury, particularly in the context of diabetic neuropathy, a common complication arising from diabetes mellitus. Using a rat model induced by streptozotocin—essentially a tool to mimic diabetes—we found that taurine significantly reduced axonal damage observed in the spinal cord.
Our analysis included both morphological and functional assessments, revealing that taurine not only ameliorated damage but also promoted neurite outgrowth in neurons exposed to high glucose levels. This suggests that taurine could play a beneficial role in repairing neural injuries associated with diabetes.
We also noted that taurine boosts the expression of nerve growth factor (NGF) and GAP-43, essential proteins for nerve growth and repair. The observed improvements seem linked to the activation of specific signaling pathways, namely the NGF-pAkt-mTOR axis. Interestingly, blocking this pathway with certain inhibitors dampened the positive effects of taurine, highlighting its crucial role in the protection and repair of neural tissues in diabetic conditions.
Overall, our findings indicate that taurine could be a promising therapeutic agent for enhancing spinal cord recovery from diabetic-induced injuries, providing hope for better management of diabetic neuropathy.
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Most Useful Reviews
9
Effective against obesity
5 people found this helpful
I'm ordering taurine again to follow Kornilova's "Insulin Resistance" scheme, which previously lowered my insulin levels and weight. I recommend it for anyone facing metabolic syndrome and related health risks like diabetes and high blood pressure. Taurine effectively combats these issues by lowering triglycerides, reducing insulin resistance for better glucose regulation, and improving overall metabolic health. If you find this review helpful, please like it.
Read More
7.5
Supports heart health
5 people found this helpful
Taurine is a beneficial amino acid for various diseases, including diabetes. Within two weeks of intake, blood glucose levels significantly decreased, and it helps mitigate diabetic vascular complications. Beyond diabetes, taurine has favourable effects on heart disease, improving metabolic processes and stabilising heart rate while lowering blood pressure. It aids in liver function, including in conditions like diabetes and enhances nutrient absorption, making it invaluable for overall health.
Read More
9
Normalises blood pressure
4 people found this helpful
My father began taking taurine post-stroke, which helped stabilise his blood pressure and reduced reliance on medication. Relatives with similar issues found taurine effective at normalising their blood pressure too. Additionally, my husband with diabetes uses taurine to help lower blood sugar effectively. I highly recommend it, although those with low blood pressure should be cautious.
We explored the impact of taurine on glial cell health in the retinas of diabetic rats and cell cultures exposed to high glucose. By conducting a thorough analysis, we found that taurine treatment significantly reduced cell death compared to untreated diabetic counterparts.
Over 8 and 12 weeks, we observed virtually no harmful cell changes in taurine-treated groups. Additionally, when retinal cells were exposed to high glucose conditions, taurine effectively reduced apoptosis across various concentrations. This suggests that taurine not only protects against cell death but also boosts the expression of a crucial taurine transporter in diabetic conditions.
Read More
9
Taurine's role in diabetic wound healing
Multifunctional Hydrogel Microneedle Patches Modulating Oxi-inflamm-aging for Diabetic Wound Healing.
We explored the role of taurine, a naturally occurring amino acid, in healing diabetic wounds. The study developed innovative patches that combine taurine with cerium dioxide, creating a unique treatment tool designed to tackle the challenges of wound healing in diabetes.
By using microneedle technology, these patches ensure that the beneficial components penetrate deep into the wound tissue. This method enhances the effectiveness of taurine, allowing it to help reduce oxidative stress and low-level inflammation commonly associated with non-healing diabetic wounds.
Our findings revealed that these specially designed patches not only stimulate healing but also improve the overall immune environment, making it easier for the body to repair damaged tissue. Ultimately, the approach harnesses taurine's antioxidant and anti-inflammatory properties, showing promising results in facilitating wound closure in diabetic patients.
Overall, the study highlights the potential of combining taurine with advanced delivery methods in overcoming obstacles to effective diabetic wound healing.
Read More
9
N-acetyltaurine impacts obesity control
PTER is a N-acetyltaurine hydrolase that regulates feeding and obesity.
We investigated the connection between taurine metabolites and their impact on feeding behavior and obesity, focusing specifically on a compound called N-acetyltaurine. Our findings revealed that N-acetyltaurine's levels in the body are influenced by various factors, including diet and exercise. One key player in the metabolism of this compound is an enzyme known as phosphotriesterase-related (PTER).
PTER serves as a crucial hydrolase, breaking down N-acetyltaurine into taurine and acetate. We discovered that when PTER is genetically removed in mice, there's a noticeable increase in N-acetyltaurine levels. This change dramatically affects the creatures' dietary habits and weight management, as these knockout mice showed reduced food intake and resented gaining weight, even when offered a high-calorie diet.
Additionally, administering N-acetyltaurine to healthy mice led to a reduction in their food consumption and overall body weight. These findings tie PTER and N-acetyltaurine into the larger narrative of how taurine influences energy balance and weight control, making them significant to understanding our metabolism and the management of obesity.
Read More
9
Taurine aids diabetic wound healing
Chitosan-taurine nanoparticles cross-linked carboxymethyl chitosan hydrogels facilitate both acute and chronic diabetic wound healing.
We delved into how taurine, paired with chitosan, can assist in healing wounds, especially in the context of diabetes. The study involved creating chitosan-taurine nanoparticles, which were then mixed into carboxymethyl chitosan hydrogels. This innovative combination aimed to enhance how well and how quickly wounds heal.
Our findings showed that these special hydrogel dressings not only supported better biodegradation and biocompatibility, but they also encouraged healing processes like angiogenesis—the formation of new blood vessels. The inclusion of taurine appears to have anti-inflammatory properties and promotes the movement and growth of cells essential for healing.
Importantly, tests on mice demonstrated that these dressings significantly improved wound healing in both acute and chronic diabetic conditions. We observed that the sustained release of taurine from the hydrogels has great potential for clinical applications in treating various types of wounds, making our study an exciting step forward in wound care.
I'm ordering taurine again to follow Kornilova's "Insulin Resistance" scheme, which previously lowered my insulin levels and weight. I recommend it for anyone facing metabolic syndrome and related health risks like diabetes and high blood pressure. Taurine effectively combats these issues by lowering triglycerides, reducing insulin resistance for better glucose regulation, and improving overall metabolic health. If you find this review helpful, please like it.
Read More
7.5
Supports heart health
5 people found this helpful
Taurine is a beneficial amino acid for various diseases, including diabetes. Within two weeks of intake, blood glucose levels significantly decreased, and it helps mitigate diabetic vascular complications. Beyond diabetes, taurine has favourable effects on heart disease, improving metabolic processes and stabilising heart rate while lowering blood pressure. It aids in liver function, including in conditions like diabetes and enhances nutrient absorption, making it invaluable for overall health.
Read More
9
Normalises blood pressure
4 people found this helpful
My father began taking taurine post-stroke, which helped stabilise his blood pressure and reduced reliance on medication. Relatives with similar issues found taurine effective at normalising their blood pressure too. Additionally, my husband with diabetes uses taurine to help lower blood sugar effectively. I highly recommend it, although those with low blood pressure should be cautious.
Read More
7.5
Protects pancreatic health
2 people found this helpful
Taurine plays an important role in medications and supplements, particularly for diabetes. With type 1 and type 2 diabetes, taurine levels significantly diminish in the body. Prolonged use lowers glycated haemoglobin and protects pancreatic beta cells, supporting insulin production effectively.
Read More
9
Essential for diabetes
1 people found this helpful
I have type 2 diabetes mellitus and take 1000mg of Taurine every night alongside metformin. Taurine is crucial for the body; it enhances carbohydrate and lipid metabolism while improving cardiovascular health. I highly recommend it.
Diabetes is a chronic medical condition that occurs when the body either does not produce enough insulin or cannot effectively use the insulin it produces. Insulin is a hormone made by the pancreas that helps glucose from food enter the cells, providing them with energy. When diabetes is present, it leads to elevated levels of glucose in the blood, which can cause serious health complications if left unmanaged. There are primarily two types: Type 1 diabetes, which is an autoimmune condition where the body attacks insulin-producing cells, and Type 2 diabetes, which is often associated with lifestyle factors such as obesity and lack of physical activity, leading to insulin resistance.
Managing diabetes typically involves a combination of lifestyle changes, such as a balanced diet and regular exercise, along with monitoring blood sugar levels and, in many cases, medication or insulin therapy. Education is crucial for those with diabetes to understand how their condition works and how to manage it effectively. The goal of diabetes management is to keep blood sugar levels within a target range, helping to prevent complications such as heart disease, nerve damage, and kidney failure. Regular check-ups and consultations with healthcare professionals are essential to ensure optimal care.
L-Taurine is a sulfonic acid and an amino acid often categorized as a conditionally essential amino acid due to its important roles in various bodily functions. Unlike most amino acids, L-Taurine is not used to synthesize proteins but is critical for several physiological processes, including bile salt formation, osmoregulation, and antioxidant defense. It’s naturally found in high concentrations in the brain, muscles, heart, and blood, playing a vital role in cardiovascular health and the maintenance of neurological function.
L-Taurine is often included in dietary supplements and energy drinks due to its potential benefits, such as enhancing exercise performance, improving recovery, and supporting overall energy levels. While the body can produce taurine from other amino acids like cysteine, some people may choose to supplement with it, particularly athletes or those seeking additional health benefits. As always, it's important to consult with a healthcare provider before starting any new supplement regimen to ensure safety and appropriateness for your individual health needs.
There is some emerging evidence suggesting that L-Taurine may have beneficial effects for individuals with diabetes, though it is not a cure or primary treatment. L-Taurine, an amino acid found in various foods and produced naturally in the body, has shown properties that could potentially aid in glucose regulation and improve insulin sensitivity. Some studies suggest that it can help lower blood sugar levels, reduce oxidative stress, and impact lipid metabolism positively, which could be beneficial for people managing diabetes. However, while these findings are promising, more extensive clinical trials are needed to establish definitive conclusions about its effectiveness and dosage.
It's essential for anyone considering L-Taurine supplementation to consult their healthcare provider, particularly if they have existing medical conditions like diabetes. The interaction with diabetic medications or overall metabolic health should be carefully monitored. Remember, maintaining a balanced diet, regular physical activity, and adhering to prescribed medications remain the cornerstone of diabetes management.
Based on user reviews, the timeline for seeing results from taking taurine for diabetes varies, but many users report noticeable improvements within a few weeks. One review indicates that significant reductions in blood glucose levels were achieved within just two weeks of starting the supplement (Read Review). Another user mentioned that after a month of use, their mother's blood sugar levels normalized (Read Review).
Additionally, some users suggest that while initial positive effects can be observed within a short timeframe, sustained use is beneficial for longer-term management of glucose levels and related health issues, such as in the case of one user who took taurine for several months and experienced a drop in glucose from 10 to 7 (Read Review). Overall, it appears that with regular supplementation, outcomes can be significant in a few weeks to a month, although individual experiences may vary.
Recent studies have begun to illuminate the potential benefits of various supplements in managing diabetes, particularly diabetes type 2. One promising candidate is cornel iridoid glycosides (CIG), which demonstrated significant antidiabetic effects in a rat model, suggesting a positive influence on metabolic disorders related to diabetes [1]. Similarly, a specialized fermented milk product improved weight loss and body composition in type 2 diabetic patients, showcasing how dietary adjustments can play an essential role in diabetes management [2].
Taurine, a naturally occurring amino acid, has also shown potential in multiple studies. It appears to enhance insulin sensitivity, improve metabolic health, and protect against oxidative damage linked to diabetes complications [15]. Moreover, taurine's combination with treatments like metformin may offer even more effective strategies for controlling blood sugar and related issues [13]. With these findings, taurine and related substances like CIG and specialized dairy products could serve as valuable supplements for those managing diabetes, alongside conventional approaches.
Based on user reviews, many individuals taking taurine report significant improvements in their symptoms related to diabetes and metabolic health. Users frequently cite reductions in blood glucose levels and insulin resistance, with one user noting that their mother normalized her blood sugar levels after a month on taurine (Read Review). Another user highlighted a substantial decrease in glucose levels from 10 to 7 over three months of supplementation (Read Review). Some participants even reported stabilization of blood pressure and a reduction in reliance on medication, showcasing taurine's potential for broader health benefits related to metabolic syndrome (Read Review).
Additionally, users attest to taurine's positive effects on weight management and other cardiovascular functions. One review indicated that consistent use led to a five-kilogram weight loss in two months, while maintaining normal sugar levels (Read Review). Many reviews emphasize that taurine not only helps regulate glucose levels but also aids in various bodily functions, from enhancing energy processes to supporting liver health and cholesterol levels. Overall, the consensus from users seems to highlight its strong role in managing diabetes and improving metabolic health, although individual results can vary.
Based on user reviews, many individuals have reported positive experiences when combining taurine with other supplements, particularly for managing diabetes. For example, one user mentioned taking taurine alongside metformin, stating that it enhances carbohydrate and lipid metabolism while improving cardiovascular health (Read Review). Another user emphasized that taurine effectively combats insulin resistance, which can be particularly beneficial for those facing metabolic syndrome and diabetes (Read Review). Additionally, users highlighted taurine’s role in supporting insulin production and protecting pancreatic beta cells, making it a promising supplemental option for individuals with diabetes in conjunction with other treatments (Read Review).
Furthermore, many users attest that taurine can enhance the effectiveness of diabetes management when used with other medications or supplements. Reports indicate that taurine helped stabilize blood sugar levels and reduce reliance on other medications, showcasing its complementary benefits (Read Review). The consensus among users suggests that taurine not only aids in maintaining glucose levels but also supports broader metabolic health, making it a valuable addition to a diabetes care regimen alongside conventional treatments (Read Review).
Based on user reviews, many individuals report that a daily dose of approximately 1000mg of L-Taurine is effective for managing diabetes and supporting metabolic health. For instance, one user noted significant improvements in blood sugar levels after consistently taking 1000mg alongside metformin, stating that taurine enhances carbohydrate and lipid metabolism while promoting overall cardiovascular health Read Review. Another review mentioned a user with type 2 diabetes successfully normalizing blood glucose levels after a month of taurine supplementation at this dosage Read Review.
Additionally, users highlighted taurine's role in reducing insulin resistance and improving the overall metabolic profile, suggesting its efficacy not just for active diabetics but also for those at risk of developing the condition Read Review. This dual effect of supporting blood sugar control and enhancing metabolic functions makes taurine a recommended supplement for individuals looking to manage diabetes or metabolic syndrome effectively. Overall, while many users found success at the 1000mg mark, they also stressed the importance of personalizing dosages under professional guidance to accommodate individual health needs and conditions.
7.5
Supports heart health
5 people found this helpful
Taurine is a beneficial amino acid for various diseases, including diabetes. Within two weeks of intake, blood glucose levels significantly decreased, and it helps mitigate diabetic vascular complications. Beyond diabetes, taurine has favourable effects on heart disease, improving metabolic processes and stabilising heart rate while lowering blood pressure. It aids in liver function, including in conditions like diabetes and enhances nutrient absorption, making it invaluable for overall health.
9
Regulates blood sugar
1 people found this helpful
My mother, who has type 2 diabetes, took Taurine for a month and her blood sugar levels are now normal.
7.5
Glucose regulation
Taurine helps regulate glucose levels. My mother, with type 2 diabetes, has been taking it for three months, and her glucose has decreased from 10 to 7. I plan to continue.
9
Normalises blood pressure
4 people found this helpful
My father began taking taurine post-stroke, which helped stabilise his blood pressure and reduced reliance on medication. Relatives with similar issues found taurine effective at normalising their blood pressure too. Additionally, my husband with diabetes uses taurine to help lower blood sugar effectively. I highly recommend it, although those with low blood pressure should be cautious.
9
Weight loss aid
1 people found this helpful
At 52 and weighing over 120 kg, I've been taking Taurine and metformin for over 9 years. My glycated haemoglobin remains stable at 4.9-5.1 mmol/L. Recently, I started a 1000mg dosage of Taurine daily, leading to a weight loss of 5 kg in 2 months while keeping my sugar levels normal. Taurine is not just for athletes but also beneficial for prediabetes and obesity.
9
Essential for diabetes
1 people found this helpful
I have type 2 diabetes mellitus and take 1000mg of Taurine every night alongside metformin. Taurine is crucial for the body; it enhances carbohydrate and lipid metabolism while improving cardiovascular health. I highly recommend it.
9
Effective against obesity
5 people found this helpful
I'm ordering taurine again to follow Kornilova's "Insulin Resistance" scheme, which previously lowered my insulin levels and weight. I recommend it for anyone facing metabolic syndrome and related health risks like diabetes and high blood pressure. Taurine effectively combats these issues by lowering triglycerides, reducing insulin resistance for better glucose regulation, and improving overall metabolic health. If you find this review helpful, please like it.
7.5
Protects pancreatic health
2 people found this helpful
Taurine plays an important role in medications and supplements, particularly for diabetes. With type 1 and type 2 diabetes, taurine levels significantly diminish in the body. Prolonged use lowers glycated haemoglobin and protects pancreatic beta cells, supporting insulin production effectively.
6
Improves insulin resistance
101 people found this helpful
Taurine is fantastic for enhancing bile flow and rheology. It positively impacts insulin resistance, lowers blood sugar in hyperglycaemia, and does not affect sugar levels at normal blood concentrations. This makes it especially helpful for individuals at risk of diabetes or those with impaired carbohydrate metabolism. It aids in the absorption of fats and fat-soluble vitamins, promotes bile outflow, and lowers cholesterol and triglycerides. I've seen only benefits from using it as recommended by my doctor, who suggested a daily intake of 1000 mg before meals.
8
Cornel iridoid glycosides effective for diabetes
Investigating the mechanism of cornel iridoid glycosides on type 2 diabetes mellitus using serum and urine metabolites in rats.
We delved into the effects of cornel iridoid glycosides (CIG) on type 2 diabetes using a rat model. After inducing diabetes with a high-fat diet and streptozotocin, we examined various health indicators and conducted detailed metabolomic analyses of serum and urine.
Our findings suggested that CIG has significant antidiabetic effects, helping to control metabolic disorders in these diabetic rats. This research paves the way for clinical applications of CIG and enhances our understanding of its metabolic mechanisms.
8
Specialized milk improves diabetes outcomes
[Assessment of the clinical effectiveness of a specialized fermented milk product for the dietary correction of carbohydrate and fat metabolism disorders].
We aimed to assess the benefits of a specialized fermented milk product on patients with type 2 diabetes who also experience abdominal obesity. Over 21 days, 40 patients were divided into two groups; one consumed the milk product while the other did not.
Good tolerability was noted, and both groups experienced significant weight loss and improvements in body composition. However, those who consumed the milk product showcased even greater benefits, such as increased vitamin levels and improved markers for fat and carbohydrate metabolism. Overall, this specialized product can be a helpful addition to diet therapy for those managing diabetes.
8
Taurine may enhance diabetes outcomes
Mitigating diabetes-related complications: Empowering metformin with cholecalciferol and taurine supplementation in type 2 diabetic rats.
We explored the potential of taurine supplementation alongside metformin to enhance diabetes management and reduce complications. In our study, we used a group of sixty rats, half of which were diabetic and received different treatments. Some rats got metformin only, while others received metformin with taurine, cholecalciferol (Vitamin D), or both.
Observations revealed that diabetic rats had serious metabolic issues, including high glucose and fat levels, as well as low antioxidant enzyme activity. However, those treated with metformin combined with taurine and cholecalciferol showed significant improvements. Their metabolic parameters, including insulin levels and islet mass, responded positively to the combined supplements.
The findings suggest that the combination of taurine and metformin may help in controlling diabetes better by reducing inflammation and oxidative stress. This approach could lead to a more effective management strategy for patients struggling with diabetes-related complications.
8
Taurine's role in diabetes therapy
Enhancing metformin efficacy with cholecalciferol and taurine in diabetes therapy: Potential and limitations.
The recent research focused on the effects of taurine, in combination with metformin and cholecalciferol (vitamin D3), on managing type 2 diabetes mellitus (T2DM) in a rat model. This interesting approach aimed to address more than just blood sugar levels, hoping to tackle related complications such as oxidative stress and inflammation.
We observed that the combination treatment showed promise in improving glycemic control and minimizing lipid issues. However, it's essential to recognize that the study does not provide a clear picture of taurine's isolated impact on diabetes, as its effects were only examined in conjunction with other substances.
Furthermore, the study was limited by a lack of safety data and detailed information about how taurine works at a molecular level. While the findings suggest potential benefits, we need to be cautious and seek further research to fully understand taurine's role and ensure its safe use in diabetes therapy.
References
Hou Y, Huang Y, Shang Z, Ma S, Cui T, et al. Investigating the mechanism of cornel iridoid glycosides on type 2 diabetes mellitus using serum and urine metabolites in rats. J Ethnopharmacol. 2024;328:118065. doi:10.1016/j.jep.2024.118065
Sharafetdinov KK, Novokshanova AL, Kochetkova AA, Plotnikova OA, Alekseeva RI, et al. [Assessment of the clinical effectiveness of a specialized fermented milk product for the dietary correction of carbohydrate and fat metabolism disorders]. Vopr Pitan. 2024;93:67. doi:10.33029/0042-8833-2024-93-6-67-75
Li YX, Lu YP, Tang D, Hu B, Zhang ZY, et al. Anthocyanin improves kidney function in diabetic kidney disease by regulating amino acid metabolism. J Transl Med. 2022;20:510. doi:10.1186/s12967-022-03717-9
Tian J, Dang H, O'Laco KA, Song M, Tiu BC, et al. Homotaurine Treatment Enhances CD4 and CD8 Regulatory T Cell Responses and Synergizes with Low-Dose Anti-CD3 to Enhance Diabetes Remission in Type 1 Diabetic Mice. Immunohorizons. 2019;3:498. doi:10.4049/immunohorizons.1900019
Zheng Y, Ceglarek U, Huang T, Wang T, Heianza Y, et al. Plasma Taurine, Diabetes Genetic Predisposition, and Changes of Insulin Sensitivity in Response to Weight-Loss Diets. J Clin Endocrinol Metab. 2016;101:3820.
Abd El-Twab SM, Mohamed HM, Mahmoud AM. Taurine and pioglitazone attenuate diabetes-induced testicular damage by abrogation of oxidative stress and up-regulation of the pituitary-gonadal axis. Can J Physiol Pharmacol. 2016;94:651. doi:10.1139/cjpp-2015-0503
Adrian TE, Gariballa S, Parekh KA, Thomas SA, Saadi H, et al. Rectal taurocholate increases L cell and insulin secretion, and decreases blood glucose and food intake in obese type 2 diabetic volunteers. Diabetologia. 2012;55:2343. doi:10.1007/s00125-012-2593-2
Song MK, Salam NK, Roufogalis BD, Huang TH. Lycium barbarum (Goji Berry) extracts and its taurine component inhibit PPAR-γ-dependent gene transcription in human retinal pigment epithelial cells: Possible implications for diabetic retinopathy treatment. Biochem Pharmacol. 2011;82:1209. doi:10.1016/j.bcp.2011.07.089
Zeng K, Xu H, Chen K, Zhu J, Zhou Y, et al. Effects of taurine on glutamate uptake and degradation in Müller cells under diabetic conditions via antioxidant mechanism. Mol Cell Neurosci. 2010;45:192. doi:10.1016/j.mcn.2010.06.010
Zeng K, Xu H, Mi M, Chen K, Zhu J, et al. Effects of taurine on glial cells apoptosis and taurine transporter expression in retina under diabetic conditions. Neurochem Res. 2010;35:1566. doi:10.1007/s11064-010-0216-1
Gaamoussi F, Israili ZH, Lyoussi B. Hypoglycemic and hypolipidemic effects of an aqueous extract of Chamaerops humilis leaves in obese, hyperglycemic and hyperlipidemic Meriones shawi rats. Pak J Pharm Sci. 2010;23:212.
Wang LJ, Yu YH, Zhang LG, Wang Y, Niu N, et al. Taurine rescues vascular endothelial dysfunction in streptozocin-induced diabetic rats: correlated with downregulation of LOX-1 and ICAM-1 expression on aortas. Eur J Pharmacol. 2008;597:75. doi:10.1016/j.ejphar.2008.08.031
El-Akabawy G, Eid N. Enhancing metformin efficacy with cholecalciferol and taurine in diabetes therapy: Potential and limitations. World J Diabetes. 2025;16:100066. doi:10.4239/wjd.v16.i1.100066
Tian S, Mei J, Zhang L, Wang S, Yuan Y, et al. Multifunctional Hydrogel Microneedle Patches Modulating Oxi-inflamm-aging for Diabetic Wound Healing. Small. 2024;20:e2407340. doi:10.1002/smll.202407340
Attia MS, Ayman F, Attia MS, Yahya G, Zahra MH, et al. Mitigating diabetes-related complications: Empowering metformin with cholecalciferol and taurine supplementation in type 2 diabetic rats. World J Diabetes. 2024;15:1778. doi:10.4239/wjd.v15.i8.1778
Wei W, Lyu X, Markhard AL, Fu S, Mardjuki RE, et al. PTER is a N-acetyltaurine hydrolase that regulates feeding and obesity. Nature. 2024;633:182. doi:10.1038/s41586-024-07801-6
Yuan J, Hou Q, He X, Zhong L, Li M, et al. Chitosan-taurine nanoparticles cross-linked carboxymethyl chitosan hydrogels facilitate both acute and chronic diabetic wound healing. Int J Biol Macromol. 2024;273:132762. doi:10.1016/j.ijbiomac.2024.132762
Simões BES, Muniz MRR, Araujo TD, Magalhães Carneiro E, Simionato AVC. Evaluation of tauroursodeoxycholic acid in liver cells' cultures by MEKC: Initial hints to comprehend its role in diabetes mellitus of obese individuals. Electrophoresis. 2024;45:1252. doi:10.1002/elps.202300223
Wang Y, Gao B, Chen X, Shi X, Li S, et al. Improvement of diabetes-induced spinal cord axon injury with taurine via nerve growth factor-dependent Akt/mTOR pathway. Amino Acids. 2024;56:32. doi:10.1007/s00726-024-03392-8
Wei W, Lyu X, Markhard AL, Fu S, Mardjuki RE, et al. A PTER-dependent pathway of taurine metabolism linked to energy balance. bioRxiv. 2024. doi:10.1101/2024.03.21.586194
Ouyang G, Wang N, Tong J, Sun W, Yang J, et al. Alleviation of taurine on liver injury of type 2 diabetic rats by improving antioxidant and anti-inflammatory capacity. Heliyon. 2024;10:e28400. doi:10.1016/j.heliyon.2024.e28400