We examined the impact of taurine, a naturally occurring amino acid, on hypothyroidism induced by thiouracil in rats. The study specifically looked at how dietary taurine influenced hypercholesterolemia, a condition where cholesterol levels are dangerously high.
Our observations revealed that hypothyroid rats experienced a notable increase in overall cholesterol levels and HDL cholesterol. Alongside these changes, we found that the rats excreted significantly fewer bile acids, which are important for digesting fats and regulating cholesterol levels.
Interestingly, taurine did not lead to any reduction in cholesterol levels, which may seem disappointing. However, it did significantly improve the excretion of bile acids. This suggests that while taurine may not tackle hypercholesterolemia head-on, it plays a role in enhancing bile acid output in the context of hypothyroidism.
Overall, our study sheds light on taurine’s selective benefits, underscoring its role in bile acid excretion despite the ongoing hypercholesterolemia in these rats. This highlights the potential therapeutic avenues for managing thyroid-induced cholesterol imbalances through dietary interventions.
Read More
9
Taurine aids hypothyroid enzyme activity
High-dose taurine supplementation increases serum paraoxonase and arylesterase activities in experimental hypothyroidism.
We explored the impact of taurine supplementation on hypothyroidism, focusing on its effects on serum enzyme activities and lipid profiles. In this study, male Sprague-Dawley rats were divided into groups, with some receiving normal diet while others were given propylthiouracil (PTU) to induce hypothyroidism. Additional groups received varying doses of taurine along with PTU.
Our findings revealed that taurine significantly increased the activities of important enzymes, paraoxonase and arylesterase, in a dose-dependent manner among the hypothyroid rats. Moreover, we observed that taurine helped lower levels of malondialdehyde, which indicates reduced oxidative stress, as well as having a positive influence on lowering triglyceride levels in the serum.
These results suggest that taurine could play a beneficial role in managing some of the metabolic disturbances associated with hypothyroidism. However, further studies, especially in human subjects, are necessary to fully understand the potential benefits of taurine in this condition.
Read More
7
Taurine may reduce oxidative stress
The effect of taurine supplementation on oxidative stress in experimental hypothyroidism.
In our research, we set out to understand how taurine, an amino acid, impacts oxidative stress in cases of experimental hypothyroidism. To do this, we used a total of forty male Sprague Dawley rats, dividing them into four groups. This included a control group, a taurine-supplemented control group, a group with induced hypothyroidism, and finally, a hypothyroid group receiving taurine.
We induced hypothyroidism in the rats using a substance called propylthiouracil (PTU) over eight weeks. Following this, we added taurine to the drinking water of one of the hypothyroid groups for five weeks. Our findings revealed that while the hypothyroid rats showed a significant increase in markers of oxidative stress in their plasma and red blood cells, taurine supplementation helped lower those levels.
However, it’s important to note that although taurine improved some oxidative stress indicators, it did not significantly change certain enzyme activities related to antioxidant properties. Overall, our study suggests that taurine may offer some protective benefits against the oxidative stress associated with hypothyroidism, making it an interesting area for further exploration in rat models.
Read More
Most Useful Reviews
9
Increased energy levels
10 people found this helpful
Really Works! I was pleasantly surprised at the effects, feeling a difference by the second day of taking it. My energy levels increased dramatically, and I felt revitalised! This is absolute happiness! My hypothyroidism seems more manageable now.
Read More
7.5
Effective diuretic
5 people found this helpful
Taurine has a diuretic effect. I took it specifically to reduce edema associated with my hypothyroidism. After enjoying the benefits for two months and gradually increasing my dose to 2000 mg, I was delighted to have lost 5 kg.
Read More
7.5
Supports metabolic health
Great Supplement! It helps to normalise blood sugar and lower insulin levels, facilitating weight loss and the excretion of excess fluid, which can affect iron levels and copper concentration in cells, thereby reducing oxidative stress. Low taurine levels are observed in hypothyroidism, dyspepsia, and anxiety; taurine plays multiple roles in the body, affecting potassium metabolism, which is necessary for energy production by thyroid hormones in the mitochondria. It retains potassium in cells and aids in energy production. Taurine is also crucial for producing glutathione, an antioxidant that helps combat free radicals and cellular damage. Additionally, it is involved in liver detoxification, supports gallbladder function, stabilises cell membranes, and promotes heart health. Taurine aids iron absorption and increases ferritin levels in AIT and hypothyroidism. Found in meat, fish, and dairy, it should not be used with bleeding issues.
We explored the impact of taurine supplementation on hypothyroidism, focusing on its effects on serum enzyme activities and lipid profiles. In this study, male Sprague-Dawley rats were divided into groups, with some receiving normal diet while others were given propylthiouracil (PTU) to induce hypothyroidism. Additional groups received varying doses of taurine along with PTU.
Our findings revealed that taurine significantly increased the activities of important enzymes, paraoxonase and arylesterase, in a dose-dependent manner among the hypothyroid rats. Moreover, we observed that taurine helped lower levels of malondialdehyde, which indicates reduced oxidative stress, as well as having a positive influence on lowering triglyceride levels in the serum.
These results suggest that taurine could play a beneficial role in managing some of the metabolic disturbances associated with hypothyroidism. However, further studies, especially in human subjects, are necessary to fully understand the potential benefits of taurine in this condition.
Read More
7
Taurine may reduce oxidative stress
The effect of taurine supplementation on oxidative stress in experimental hypothyroidism.
In our research, we set out to understand how taurine, an amino acid, impacts oxidative stress in cases of experimental hypothyroidism. To do this, we used a total of forty male Sprague Dawley rats, dividing them into four groups. This included a control group, a taurine-supplemented control group, a group with induced hypothyroidism, and finally, a hypothyroid group receiving taurine.
We induced hypothyroidism in the rats using a substance called propylthiouracil (PTU) over eight weeks. Following this, we added taurine to the drinking water of one of the hypothyroid groups for five weeks. Our findings revealed that while the hypothyroid rats showed a significant increase in markers of oxidative stress in their plasma and red blood cells, taurine supplementation helped lower those levels.
However, it’s important to note that although taurine improved some oxidative stress indicators, it did not significantly change certain enzyme activities related to antioxidant properties. Overall, our study suggests that taurine may offer some protective benefits against the oxidative stress associated with hypothyroidism, making it an interesting area for further exploration in rat models.
Read More
4
Taurine improves bile acid excretion
Improved suppression by dietary taurine of the fecal excretion of bile acids from hypothyroid rats.
We examined the impact of taurine, a naturally occurring amino acid, on hypothyroidism induced by thiouracil in rats. The study specifically looked at how dietary taurine influenced hypercholesterolemia, a condition where cholesterol levels are dangerously high.
Our observations revealed that hypothyroid rats experienced a notable increase in overall cholesterol levels and HDL cholesterol. Alongside these changes, we found that the rats excreted significantly fewer bile acids, which are important for digesting fats and regulating cholesterol levels.
Interestingly, taurine did not lead to any reduction in cholesterol levels, which may seem disappointing. However, it did significantly improve the excretion of bile acids. This suggests that while taurine may not tackle hypercholesterolemia head-on, it plays a role in enhancing bile acid output in the context of hypothyroidism.
Overall, our study sheds light on taurine’s selective benefits, underscoring its role in bile acid excretion despite the ongoing hypercholesterolemia in these rats. This highlights the potential therapeutic avenues for managing thyroid-induced cholesterol imbalances through dietary interventions.
Read More
User Reviews
USERS' SCORE
Good
Based on 4 Reviews
8.4
All Reviews
Positive Reviews
Negative Reviews
9
Increased energy levels
10 people found this helpful
Really Works! I was pleasantly surprised at the effects, feeling a difference by the second day of taking it. My energy levels increased dramatically, and I felt revitalised! This is absolute happiness! My hypothyroidism seems more manageable now.
Read More
7.5
Effective diuretic
5 people found this helpful
Taurine has a diuretic effect. I took it specifically to reduce edema associated with my hypothyroidism. After enjoying the benefits for two months and gradually increasing my dose to 2000 mg, I was delighted to have lost 5 kg.
Read More
7.5
Supports metabolic health
Great Supplement! It helps to normalise blood sugar and lower insulin levels, facilitating weight loss and the excretion of excess fluid, which can affect iron levels and copper concentration in cells, thereby reducing oxidative stress. Low taurine levels are observed in hypothyroidism, dyspepsia, and anxiety; taurine plays multiple roles in the body, affecting potassium metabolism, which is necessary for energy production by thyroid hormones in the mitochondria. It retains potassium in cells and aids in energy production. Taurine is also crucial for producing glutathione, an antioxidant that helps combat free radicals and cellular damage. Additionally, it is involved in liver detoxification, supports gallbladder function, stabilises cell membranes, and promotes heart health. Taurine aids iron absorption and increases ferritin levels in AIT and hypothyroidism. Found in meat, fish, and dairy, it should not be used with bleeding issues.
Read More
7.5
Effective for weight loss
9 people found this helpful
Works! I have AIT hypothyroidism and took Taurine to help cope with edema. In just one month of taking it, I lost 5kg (hurray!), likely due to excess water leaving my body. I usually have low blood pressure, but this supplement does not seem to affect it. I take it in the morning on an empty stomach.
Read More
Frequently Asked Questions
Hypothyroidism is a medical condition that occurs when the thyroid gland, a small butterfly-shaped gland located at the base of the neck, does not produce enough thyroid hormones. These hormones, mainly thyroxine (T4) and triiodothyronine (T3), play a critical role in regulating various bodily functions, including metabolism, energy production, and overall growth and development. When hormone levels drop, it can lead to a slow metabolism, weight gain, fatigue, depression, and a host of other symptoms that can significantly affect quality of life.
The condition can be caused by a variety of factors, including autoimmune diseases like Hashimoto's thyroiditis, certain medications, radiation treatment, or iodine deficiency. Diagnosis typically involves blood tests to check levels of thyroid-stimulating hormone (TSH) and thyroid hormones. Treatment primarily includes hormone replacement therapy, with synthetic thyroid hormones such as levothyroxine being the most common form of treatment. With proper management, individuals with hypothyroidism can lead normal, healthy lives by ensuring they receive the necessary hormones their bodies need to function optimally.
L-Taurine is a sulfonic acid and an amino acid often categorized as a conditionally essential amino acid due to its important roles in various bodily functions. Unlike most amino acids, L-Taurine is not used to synthesize proteins but is critical for several physiological processes, including bile salt formation, osmoregulation, and antioxidant defense. It’s naturally found in high concentrations in the brain, muscles, heart, and blood, playing a vital role in cardiovascular health and the maintenance of neurological function.
L-Taurine is often included in dietary supplements and energy drinks due to its potential benefits, such as enhancing exercise performance, improving recovery, and supporting overall energy levels. While the body can produce taurine from other amino acids like cysteine, some people may choose to supplement with it, particularly athletes or those seeking additional health benefits. As always, it's important to consult with a healthcare provider before starting any new supplement regimen to ensure safety and appropriateness for your individual health needs.
Based on user reviews, individuals taking taurine as a supplement for hypothyroidism generally report experiencing results within a relatively short timeframe. For instance, one user noted feeling a noticeable difference just by the second day of taking the supplement, including increased energy levels and a more manageable condition overall Read Review. Another reviewer mentioned achieving significant benefits for weight loss and reduced edema after two months of consistent use, with adjustments made to their dosage Read Review.
Additionally, several users highlighted that they observed beneficial effects, such as lower insulin levels and improved blood sugar, within a short duration of use. One user particularly mentioned that after a month of supplementation, they experienced tangible results, including a noticeable weight loss attributed to the supplement's diuretic properties Read Review. Overall, while results can vary, many users suggest that improvements can often be felt within the first month or even sooner.
Taurine has shown some promising effects in studies related to hypothyroidism, particularly in animal models. In research conducted on hypothyroid rats, taurine supplementation was found to significantly enhance the activities of important enzymes and reduce oxidative stress indicators, thus suggesting potential metabolic benefits associated with hypothyroidism management [1]. Another study demonstrated that taurine helped mitigate markers of oxidative stress in hypothyroid conditions, although it did not significantly alter certain antioxidant enzyme activities [2].
Furthermore, while taurine did not reduce cholesterol levels in hypothyroid rats, it was observed to improve bile acid excretion, hinting at possible benefits in managing cholesterol imbalances commonly associated with thyroid dysfunction [3]. However, it is essential to note that these findings are primarily based on animal studies, and more research, particularly in human subjects, is necessary to definitively establish taurine's efficacy as a supplement for hypothyroidism.
Based on user reviews, individuals using taurine supplements for hypothyroidism report a range of improvements in their symptoms, particularly in terms of energy levels and weight management. For instance, one user experienced a significant boost in energy just two days after starting the supplement, noting an overall reduction in the challenges posed by hypothyroidism Read Review. Additionally, another reviewer highlighted the diuretic properties of taurine, stating that after two months, they not only managed to lose 5 kg but also saw a reduction in edema associated with their condition Read Review.
Moreover, several users shared observations related to blood sugar regulation and overall metabolic health. One user specifically mentioned the effectiveness of taurine in normalizing blood sugar levels and reducing insulin, further supporting their weight loss journey and fluid retention issues Read Review. Another noted similar weight loss results within just a month of supplementation while managing to maintain stable blood pressure Read Review. While results can vary significantly from person to person, many users seem to experience positive changes reasonably quickly after incorporating taurine into their routine.
Users report that combining taurine with other supplements can yield synergistic benefits for managing hypothyroidism symptoms. For instance, one reviewer mentioned that taurine effectively normalizes blood sugar levels and lowers insulin, which plays a crucial role in weight loss and helps manage fluid retention associated with their condition Read Review. This suggests that a comprehensive approach, possibly involving additional supplements for blood sugar management, might enhance overall effectiveness in dealing with hypothyroidism.
Additionally, anecdotal evidence from users indicates that taurine's diuretic properties, when combined with a well-rounded supplement regimen, can lead to significant weight loss and reduction in edema Read Review. One user specifically noted a 5 kg weight loss alongside managing their hypothyroidism symptoms effectively while taking taurine, highlighting how its effects may be amplified when used alongside other supportive supplements for thyroid health Read Review. However, as always, it's important for users to consult healthcare providers to tailor their supplement combinations effectively.
Based on user reviews regarding the dosage of L-Taurine for treating hypothyroidism, it seems that many individuals have gradually increased their intake to find their optimal dose. One user noted that after two months of taking Taurine, they increased their dosage to 2000 mg, which contributed to their weight loss and was effective in managing edema associated with their condition Read Review. Another user, who took Taurine specifically for hypothyroidism, also reported losing weight and managing their symptoms, though they did not specify a dosage Read Review.
Overall, it appears that users advocate for a personalized approach to determining the right dose, with some users finding success at the 2000 mg mark, while others simply report positive effects without mentioning specific dosages. Those with varying responses may want to start with a lower dose and adjust as needed, keeping in mind their individual health conditions and monitoring any changes Read Review.
9
Increased energy levels
10 people found this helpful
Really Works! I was pleasantly surprised at the effects, feeling a difference by the second day of taking it. My energy levels increased dramatically, and I felt revitalised! This is absolute happiness! My hypothyroidism seems more manageable now.
7.5
Effective diuretic
5 people found this helpful
Taurine has a diuretic effect. I took it specifically to reduce edema associated with my hypothyroidism. After enjoying the benefits for two months and gradually increasing my dose to 2000 mg, I was delighted to have lost 5 kg.
7.5
Effective for weight loss
9 people found this helpful
Works! I have AIT hypothyroidism and took Taurine to help cope with edema. In just one month of taking it, I lost 5kg (hurray!), likely due to excess water leaving my body. I usually have low blood pressure, but this supplement does not seem to affect it. I take it in the morning on an empty stomach.
7.5
Supports metabolic health
Great Supplement! It helps to normalise blood sugar and lower insulin levels, facilitating weight loss and the excretion of excess fluid, which can affect iron levels and copper concentration in cells, thereby reducing oxidative stress. Low taurine levels are observed in hypothyroidism, dyspepsia, and anxiety; taurine plays multiple roles in the body, affecting potassium metabolism, which is necessary for energy production by thyroid hormones in the mitochondria. It retains potassium in cells and aids in energy production. Taurine is also crucial for producing glutathione, an antioxidant that helps combat free radicals and cellular damage. Additionally, it is involved in liver detoxification, supports gallbladder function, stabilises cell membranes, and promotes heart health. Taurine aids iron absorption and increases ferritin levels in AIT and hypothyroidism. Found in meat, fish, and dairy, it should not be used with bleeding issues.
9
Taurine aids hypothyroid enzyme activity
High-dose taurine supplementation increases serum paraoxonase and arylesterase activities in experimental hypothyroidism.
We explored the impact of taurine supplementation on hypothyroidism, focusing on its effects on serum enzyme activities and lipid profiles. In this study, male Sprague-Dawley rats were divided into groups, with some receiving normal diet while others were given propylthiouracil (PTU) to induce hypothyroidism. Additional groups received varying doses of taurine along with PTU.
Our findings revealed that taurine significantly increased the activities of important enzymes, paraoxonase and arylesterase, in a dose-dependent manner among the hypothyroid rats. Moreover, we observed that taurine helped lower levels of malondialdehyde, which indicates reduced oxidative stress, as well as having a positive influence on lowering triglyceride levels in the serum.
These results suggest that taurine could play a beneficial role in managing some of the metabolic disturbances associated with hypothyroidism. However, further studies, especially in human subjects, are necessary to fully understand the potential benefits of taurine in this condition.
7
Taurine may reduce oxidative stress
The effect of taurine supplementation on oxidative stress in experimental hypothyroidism.
In our research, we set out to understand how taurine, an amino acid, impacts oxidative stress in cases of experimental hypothyroidism. To do this, we used a total of forty male Sprague Dawley rats, dividing them into four groups. This included a control group, a taurine-supplemented control group, a group with induced hypothyroidism, and finally, a hypothyroid group receiving taurine.
We induced hypothyroidism in the rats using a substance called propylthiouracil (PTU) over eight weeks. Following this, we added taurine to the drinking water of one of the hypothyroid groups for five weeks. Our findings revealed that while the hypothyroid rats showed a significant increase in markers of oxidative stress in their plasma and red blood cells, taurine supplementation helped lower those levels.
However, it’s important to note that although taurine improved some oxidative stress indicators, it did not significantly change certain enzyme activities related to antioxidant properties. Overall, our study suggests that taurine may offer some protective benefits against the oxidative stress associated with hypothyroidism, making it an interesting area for further exploration in rat models.
4
Taurine improves bile acid excretion
Improved suppression by dietary taurine of the fecal excretion of bile acids from hypothyroid rats.
We examined the impact of taurine, a naturally occurring amino acid, on hypothyroidism induced by thiouracil in rats. The study specifically looked at how dietary taurine influenced hypercholesterolemia, a condition where cholesterol levels are dangerously high.
Our observations revealed that hypothyroid rats experienced a notable increase in overall cholesterol levels and HDL cholesterol. Alongside these changes, we found that the rats excreted significantly fewer bile acids, which are important for digesting fats and regulating cholesterol levels.
Interestingly, taurine did not lead to any reduction in cholesterol levels, which may seem disappointing. However, it did significantly improve the excretion of bile acids. This suggests that while taurine may not tackle hypercholesterolemia head-on, it plays a role in enhancing bile acid output in the context of hypothyroidism.
Overall, our study sheds light on taurine’s selective benefits, underscoring its role in bile acid excretion despite the ongoing hypercholesterolemia in these rats. This highlights the potential therapeutic avenues for managing thyroid-induced cholesterol imbalances through dietary interventions.
References
Dirican M, Taş S, Sarandöl E. High-dose taurine supplementation increases serum paraoxonase and arylesterase activities in experimental hypothyroidism. Clin Exp Pharmacol Physiol. 2007;34:833.
Taş S, Dirican M, Sarandöl E, Serdar Z. The effect of taurine supplementation on oxidative stress in experimental hypothyroidism. Cell Biochem Funct. 2006;24:153.
Mochizuki H, Takido J, Yokogoshi H. Improved suppression by dietary taurine of the fecal excretion of bile acids from hypothyroid rats. Biosci Biotechnol Biochem. 1999;63:753.