Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Good
Based on 15 Reviews
8.3
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
L-Glutamine
1,000 mg

Top Medical Research Studies

8
Effectiveness of L-glutamine unclear
We examined a case report detailing the naturopathic management of functional dyspepsia, particularly focusing on a 25-year-old female graduate student experiencing several gastrointestinal issues such as bloating, epigastric pain, and reflux. While the report highlighted the use of L-glutamine along with other interventions, it did not provide specific data on how effective L-glutamine was on its own in alleviating reflux symptoms.

The patient underwent a treatment regimen that included an elimination diet and the use of apple cider vinegar alongside L-glutamine. Within a week of starting the treatment, the patient reported significant improvement in her symptoms. Notably, by the end of one month, she had resolved nearly all symptoms, with the exception of straining during bowel movements.

However, because L-glutamine was used in combination with other therapies, we cannot definitively assess its isolated impact on reflux symptoms. While the overall approach showed promise for symptom relief, the study’s design did not allow for a clear understanding of L-glutamine’s specific role in treating reflux.
Read More

Most Useful Reviews

8.8
Healing leaky gut
Healing intestinal hyperpermeability, or 'leaky gut'. I discovered I had leaky gut alongside an autoimmune thyroid disease. My only GI symptoms were a gradual onset of acid reflux and slight lactose intolerance. I initially used high doses of prilosec temporarily, then high-dose probiotics and digestive enzymes. Within weeks, I noticed significant improvements, better absorption of food and nutrients, and a reduction in acid reflux. I highly recommend L-glutamine for anyone dealing with leaky gut or similar issues.
Read More
9.5
Best IBS supplement
Simply the BEST supplement for IBS that I have ever used! Suffering from IBS-C for over 10 years, I faced numerous tests suggesting I was healthy while my symptoms worsened. Recently, I experienced severe acid reflux and intestinal sensitivities. I found L-glutamine which helps reduce IBS symptoms by healing the large intestine's mucous membrane. I noticed improvements almost immediately after starting it, making me believe it is a game changer for my gut health.
Read More
9.5
Eliminates reflux
Jarrow Formulas L-Glutamine 1000 has been excellent for my heartburn and reflux. I was previously on acid blockers, which provided some relief, yet I still experienced heartburn and reflux. Following a nutritionist's advice, I began taking both L-Glutamine and PepZinGI, ultimately stopping the acid blockers. Now, I no longer suffer from reflux and rarely have heartburn. I take four L-Glutamine capsules each morning on an empty stomach and two PepZinGI tablets with food. I've noticed that L-Glutamine alone performs exceptionally well, as I forgot to take PepZinGI a couple of times without experiencing symptoms. Nonetheless, PepZinGI is necessary, as I faced some recurring symptoms after a week without it.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
  • All Researches
8
Effectiveness of L-glutamine unclear
We examined a case report detailing the naturopathic management of functional dyspepsia, particularly focusing on a 25-year-old female graduate student experiencing several gastrointestinal issues such as bloating, epigastric pain, and reflux. While the report highlighted the use of L-glutamine along with other interventions, it did not provide specific data on how effective L-glutamine was on its own in alleviating reflux symptoms.

The patient underwent a treatment regimen that included an elimination diet and the use of apple cider vinegar alongside L-glutamine. Within a week of starting the treatment, the patient reported significant improvement in her symptoms. Notably, by the end of one month, she had resolved nearly all symptoms, with the exception of straining during bowel movements.

However, because L-glutamine was used in combination with other therapies, we cannot definitively assess its isolated impact on reflux symptoms. While the overall approach showed promise for symptom relief, the study’s design did not allow for a clear understanding of L-glutamine’s specific role in treating reflux.
Read More

User Reviews

USERS' SCORE
Good
Based on 15 Reviews
8.3
  • All Reviews
  • Positive Reviews
  • Negative Reviews
8.8
Healing leaky gut
Healing intestinal hyperpermeability, or 'leaky gut'. I discovered I had leaky gut alongside an autoimmune thyroid disease. My only GI symptoms were a gradual onset of acid reflux and slight lactose intolerance. I initially used high doses of prilosec temporarily, then high-dose probiotics and digestive enzymes. Within weeks, I noticed significant improvements, better absorption of food and nutrients, and a reduction in acid reflux. I highly recommend L-glutamine for anyone dealing with leaky gut or similar issues.
Read More
9.5
Best IBS supplement
Simply the BEST supplement for IBS that I have ever used! Suffering from IBS-C for over 10 years, I faced numerous tests suggesting I was healthy while my symptoms worsened. Recently, I experienced severe acid reflux and intestinal sensitivities. I found L-glutamine which helps reduce IBS symptoms by healing the large intestine's mucous membrane. I noticed improvements almost immediately after starting it, making me believe it is a game changer for my gut health.
Read More
9.5
Eliminates reflux
Jarrow Formulas L-Glutamine 1000 has been excellent for my heartburn and reflux. I was previously on acid blockers, which provided some relief, yet I still experienced heartburn and reflux. Following a nutritionist's advice, I began taking both L-Glutamine and PepZinGI, ultimately stopping the acid blockers. Now, I no longer suffer from reflux and rarely have heartburn. I take four L-Glutamine capsules each morning on an empty stomach and two PepZinGI tablets with food. I've noticed that L-Glutamine alone performs exceptionally well, as I forgot to take PepZinGI a couple of times without experiencing symptoms. Nonetheless, PepZinGI is necessary, as I faced some recurring symptoms after a week without it.
Read More
9.5
Significant improvement
Relief for leaky gut and acid reflux. I was diagnosed with both conditions and tried numerous supplements without success. After reading about L-Glutamine, I decided to try it. It has been a Godsend, bringing me significant improvement. I take it on an empty stomach and am extremely grateful for the relief it provides.
Read More
8.8
Controls reflux effectively
This product is a lifesaver for those suffering from gastroesophageal reflux. Although I initially tried Super Enzymes and later Pepsin HCL to see improvement, I still faced occasional issues, prompting me to increase the dosage. Now, I take one tablet of Jarrow Formulas L-Glutamine each morning and one on an empty stomach. After a week, I noticed that my gastroesophageal reflux was much better controlled, and increasing my coffee intake no longer triggers any reflux symptoms.
Read More

Frequently Asked Questions

Reflux, medically known as gastroesophageal reflux disease (GERD), occurs when stomach acid flows back into the esophagus, the tube that connects the throat to the stomach. This backflow can lead to symptoms such as heartburn, regurgitation, and difficulty swallowing. Reflux can affect people of all ages and may be triggered or worsened by factors such as diet, obesity, smoking, and certain medications. While occasional reflux is common and often manageable with lifestyle changes, chronic reflux can lead to more serious complications if not properly treated.

Managing reflux typically involves a combination of lifestyle modifications—such as avoiding trigger foods, eating smaller meals, and maintaining a healthy weight—and, in some cases, medication to reduce stomach acid production. In more severe cases, surgical options may be considered. If you suspect you have reflux or experience frequent symptoms, it’s advisable to consult a healthcare professional for an accurate diagnosis and personalized treatment plan.

L-glutamine is an amino acid that is classified as a conditionally essential amino acid, meaning that while the body usually produces enough of it, there may be times — like during illness, injury, or intense physical activity — when supplementation can be beneficial. It plays a crucial role in various physiological functions, including protein synthesis, immune system support, and maintaining gut health. Glutamine is particularly important for athletes and those engaging in heavy workouts, as it can help in muscle recovery and reduce muscle soreness after exercise.

In terms of dietary sources, L-glutamine is naturally found in high-protein foods such as beef, chicken, fish, eggs, dairy products, and certain plant-based foods like beans, lentils, and spinach. Many people choose to take L-glutamine supplements to bolster their intake, particularly when they are involved in rigorous training or are recovering from surgery or trauma. However, as with any supplement, it’s advisable to consult healthcare professionals before starting to ensure it aligns with your health needs and dietary goals.

L-Glutamine is an amino acid that plays a critical role in gut health and may contribute to healing the intestinal lining. While there is some evidence suggesting that L-Glutamine can help support digestive health and reduce intestinal permeability, its direct effect on reflux or gastroesophageal reflux disease (GERD) specifically is not well established. Some individuals report improvements in their overall digestive comfort with the inclusion of L-Glutamine in their regimen, but this varies from person to person.

If you are experiencing reflux, it is essential to approach treatment holistically. Alongside any supplements, considering dietary changes, lifestyle modifications, and consulting with a healthcare professional can provide a comprehensive management approach to reduce symptoms of reflux. As always, it’s advisable to discuss with your doctor before starting any new supplement, including L-Glutamine, especially if you have pre-existing health conditions or are taking medications. They can help you determine the best path forward based on your individual needs.

Based on user reviews, many individuals taking L-Glutamine for reflux have reported noticeable improvements within a week of consistent use. For instance, one user mentioned that after a week of taking the supplement, their gastroesophageal reflux was much better controlled, indicating that it took a short period to begin feeling relief (Read Review). Another user also emphasized experiencing a significant reduction in heartburn after beginning the supplement, further suggesting that users can potentially see results in approximately one week of regular intake (Read Review).

However, individual experiences may vary, and some users have indicated that a combination of L-Glutamine with other supplements resulted in even better outcomes, implying that the effectiveness might improve when used in tandem with supportive herbs or enzymes (Read Review). Overall, it appears that while initial relief can often be noted within a week, achieving optimal results might depend on individual circumstances and any additional remedies being utilized.

The available research on L-glutamine's efficacy for reflux is limited and does not provide a conclusive answer. A case report examined its use in conjunction with other treatments for a young woman experiencing gastrointestinal issues, including reflux. While the treatment approach showed some promise—resulting in significant symptom improvement—the study did not isolate L-glutamine's effects from other interventions, such as an elimination diet and apple cider vinegar [1]. This lack of specific data makes it difficult to determine whether L-glutamine is effective on its own for reflux relief.

Based on user reviews, many individuals have reported significant improvements in their symptoms of heartburn and gastroesophageal reflux after incorporating L-Glutamine into their daily routine. For example, one user detailed how the supplement helped them completely eliminate reflux symptoms and greatly reduce heartburn, allowing them to discontinue the use of acid blockers (Read Review). Another reviewer observed a marked reduction in their reflux symptoms after just one week of use, noting that even an increase in coffee consumption no longer triggered their reflux (Read Review).

Users have also mentioned varying degrees of relief, with some feeling pleased about the reduction in acid reflux without any side effects, while others indicated that combining L-Glutamine with enzymes enhanced the results (Read Review). Noteworthy is the experience of those suffering from more chronic conditions, such as reflux esophagitis, who reported notable alleviation of discomfort while taking the supplement (Read Review). While a majority are satisfied with the effectiveness of L-Glutamine, it's essential to remember that individual experiences can vary.

Users have reported varied experiences when combining L-Glutamine with other supplements to manage reflux symptoms. One user noted significant improvements, stating that while L-Glutamine alone provided substantial relief, adding PepZinGI was key to preventing recurring symptoms, underscoring the potential benefits of this combination (Read Review). Another user echoed this sentiment, indicating that pairing L-Glutamine with enzymes had enhanced their overall results (Read Review).

Additionally, a reviewer mentioned using L-Glutamine in conjunction with prescribed medications and enzymes for their mother's reflux esophagitis, yielding effective results (Read Review). This suggests that while L-Glutamine can be beneficial on its own, combining it with specific supportive supplements may offer users improved management of their reflux symptoms.

Users report varying doses of L-Glutamine for treating reflux, generally emphasizing that it has provided significant relief. One user mentioned that they take four capsules each morning on an empty stomach, noting the effectiveness of this dose in eliminating their symptoms of reflux and heartburn (Read Review). Another user found success with a lower dose, taking one tablet in the morning and another on an empty stomach, which they found sufficient to manage their gastroesophageal reflux effectively (Read Review).

Some users have also observed that the results of L-Glutamine can be enhanced when paired with other supplements. For instance, one reviewer noted an improvement in their symptoms when combining L-Glutamine with supportive herbs (Read Review). Overall, while individual responses to dosage can vary, a trend toward higher doses (like four capsules) and combinations with other aids appear to yield favorable outcomes for reflux sufferers.

8.8
Controls reflux effectively
This product is a lifesaver for those suffering from gastroesophageal reflux. Although I initially tried Super Enzymes and later Pepsin HCL to see improvement, I still faced occasional issues, prompting me to increase the dosage. Now, I take one tablet of Jarrow Formulas L-Glutamine each morning and one on an empty stomach. After a week, I noticed that my gastroesophageal reflux was much better controlled, and increasing my coffee intake no longer triggers any reflux symptoms.
9.5
Significant heartburn drop
My husband and I have noticed a considerable reduction in heartburn and acid reflux since we began taking L-Glutamine. Thankfully, we haven’t experienced any adverse side effects either!
5.5
Effective support
Alright. I took this for my reflux, and I found that this amino acid works more effectively when combined with other supportive herbs.
9.5
Eliminates reflux
Jarrow Formulas L-Glutamine 1000 has been excellent for my heartburn and reflux. I was previously on acid blockers, which provided some relief, yet I still experienced heartburn and reflux. Following a nutritionist's advice, I began taking both L-Glutamine and PepZinGI, ultimately stopping the acid blockers. Now, I no longer suffer from reflux and rarely have heartburn. I take four L-Glutamine capsules each morning on an empty stomach and two PepZinGI tablets with food. I've noticed that L-Glutamine alone performs exceptionally well, as I forgot to take PepZinGI a couple of times without experiencing symptoms. Nonetheless, PepZinGI is necessary, as I faced some recurring symptoms after a week without it.
9.5
Definitely effective
I purchased this for my mother, who has long-lasting symptoms of reflux esophagitis. She takes this in conjunction with two enzymes and prescribed medications, and the results have been evidently effective.
8
Effectiveness of L-glutamine unclear
We examined a case report detailing the naturopathic management of functional dyspepsia, particularly focusing on a 25-year-old female graduate student experiencing several gastrointestinal issues such as bloating, epigastric pain, and reflux. While the report highlighted the use of L-glutamine along with other interventions, it did not provide specific data on how effective L-glutamine was on its own in alleviating reflux symptoms.

The patient underwent a treatment regimen that included an elimination diet and the use of apple cider vinegar alongside L-glutamine. Within a week of starting the treatment, the patient reported significant improvement in her symptoms. Notably, by the end of one month, she had resolved nearly all symptoms, with the exception of straining during bowel movements.

However, because L-glutamine was used in combination with other therapies, we cannot definitively assess its isolated impact on reflux symptoms. While the overall approach showed promise for symptom relief, the study’s design did not allow for a clear understanding of L-glutamine’s specific role in treating reflux.

References

  1. Pistoia JC, Chandler L. Naturopathic Approach to Functional Dyspepsia: A Case Report. Integr Med (Encinitas). 2021;20:32.
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