Last update
5/3/2025

Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Moderately Good
Based on 15 Reviews
7.1
Supplement Facts
Serving Size: 1 Tablet
Amount Per Serving
%DV
L-Glutamine
1,000 mg

Top Medical Research Studies

8
Effectiveness of L-glutamine unclear
We examined a case report detailing the naturopathic management of functional dyspepsia, particularly focusing on a 25-year-old female graduate student experiencing several gastrointestinal issues such as bloating, epigastric pain, and reflux. While the report highlighted the use of L-glutamine along with other interventions, it did not provide specific data on how effective L-glutamine was on its own in alleviating reflux symptoms.

The patient underwent a treatment regimen that included an elimination diet and the use of apple cider vinegar alongside L-glutamine. Within a week of starting the treatment, the patient reported significant improvement in her symptoms. Notably, by the end of one month, she had resolved nearly all symptoms, with the exception of straining during bowel movements.

However, because L-glutamine was used in combination with other therapies, we cannot definitively assess its isolated impact on reflux symptoms. While the overall approach showed promise for symptom relief, the study’s design did not allow for a clear understanding of L-glutamine’s specific role in treating reflux.
Read More

Most Useful Reviews

7.5
Healing leaky gut
162 people found this helpful
Healing intestinal hyperpermeability, or 'leaky gut'. I discovered I had leaky gut alongside an autoimmune thyroid disease. My only GI symptoms were a gradual onset of acid reflux and slight lactose intolerance. I initially used high doses of prilosec temporarily, then high-dose probiotics and digestive enzymes. Within weeks, I noticed significant improvements, better absorption of food and nutrients, and a reduction in acid reflux. I highly recommend L-glutamine for anyone dealing with leaky gut or similar issues.
Read More
9
Best IBS supplement
141 people found this helpful
Simply the BEST supplement for IBS that I have ever used! Suffering from IBS-C for over 10 years, I faced numerous tests suggesting I was healthy while my symptoms worsened. Recently, I experienced severe acid reflux and intestinal sensitivities. I found L-glutamine which helps reduce IBS symptoms by healing the large intestine's mucous membrane. I noticed improvements almost immediately after starting it, making me believe it is a game changer for my gut health.
Read More
9
Eliminates reflux
17 people found this helpful
Jarrow Formulas L-Glutamine 1000 has been excellent for my heartburn and reflux. I was previously on acid blockers, which provided some relief, yet I still experienced heartburn and reflux. Following a nutritionist's advice, I began taking both L-Glutamine and PepZinGI, ultimately stopping the acid blockers. Now, I no longer suffer from reflux and rarely have heartburn. I take four L-Glutamine capsules each morning on an empty stomach and two PepZinGI tablets with food. I've noticed that L-Glutamine alone performs exceptionally well, as I forgot to take PepZinGI a couple of times without experiencing symptoms. Nonetheless, PepZinGI is necessary, as I faced some recurring symptoms after a week without it.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
  • All Researches
8
Effectiveness of L-glutamine unclear
We examined a case report detailing the naturopathic management of functional dyspepsia, particularly focusing on a 25-year-old female graduate student experiencing several gastrointestinal issues such as bloating, epigastric pain, and reflux. While the report highlighted the use of L-glutamine along with other interventions, it did not provide specific data on how effective L-glutamine was on its own in alleviating reflux symptoms.

The patient underwent a treatment regimen that included an elimination diet and the use of apple cider vinegar alongside L-glutamine. Within a week of starting the treatment, the patient reported significant improvement in her symptoms. Notably, by the end of one month, she had resolved nearly all symptoms, with the exception of straining during bowel movements.

However, because L-glutamine was used in combination with other therapies, we cannot definitively assess its isolated impact on reflux symptoms. While the overall approach showed promise for symptom relief, the study’s design did not allow for a clear understanding of L-glutamine’s specific role in treating reflux.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 15 Reviews
7.1
  • All Reviews
  • Positive Reviews
  • Negative Reviews
7.5
Healing leaky gut
162 people found this helpful
Healing intestinal hyperpermeability, or 'leaky gut'. I discovered I had leaky gut alongside an autoimmune thyroid disease. My only GI symptoms were a gradual onset of acid reflux and slight lactose intolerance. I initially used high doses of prilosec temporarily, then high-dose probiotics and digestive enzymes. Within weeks, I noticed significant improvements, better absorption of food and nutrients, and a reduction in acid reflux. I highly recommend L-glutamine for anyone dealing with leaky gut or similar issues.
Read More
9
Best IBS supplement
141 people found this helpful
Simply the BEST supplement for IBS that I have ever used! Suffering from IBS-C for over 10 years, I faced numerous tests suggesting I was healthy while my symptoms worsened. Recently, I experienced severe acid reflux and intestinal sensitivities. I found L-glutamine which helps reduce IBS symptoms by healing the large intestine's mucous membrane. I noticed improvements almost immediately after starting it, making me believe it is a game changer for my gut health.
Read More
9
Eliminates reflux
17 people found this helpful
Jarrow Formulas L-Glutamine 1000 has been excellent for my heartburn and reflux. I was previously on acid blockers, which provided some relief, yet I still experienced heartburn and reflux. Following a nutritionist's advice, I began taking both L-Glutamine and PepZinGI, ultimately stopping the acid blockers. Now, I no longer suffer from reflux and rarely have heartburn. I take four L-Glutamine capsules each morning on an empty stomach and two PepZinGI tablets with food. I've noticed that L-Glutamine alone performs exceptionally well, as I forgot to take PepZinGI a couple of times without experiencing symptoms. Nonetheless, PepZinGI is necessary, as I faced some recurring symptoms after a week without it.
Read More
9
Significant improvement
13 people found this helpful
Relief for leaky gut and acid reflux. I was diagnosed with both conditions and tried numerous supplements without success. After reading about L-Glutamine, I decided to try it. It has been a Godsend, bringing me significant improvement. I take it on an empty stomach and am extremely grateful for the relief it provides.
Read More
7.5
Controls reflux effectively
5 people found this helpful
This product is a lifesaver for those suffering from gastroesophageal reflux. Although I initially tried Super Enzymes and later Pepsin HCL to see improvement, I still faced occasional issues, prompting me to increase the dosage. Now, I take one tablet of Jarrow Formulas L-Glutamine each morning and one on an empty stomach. After a week, I noticed that my gastroesophageal reflux was much better controlled, and increasing my coffee intake no longer triggers any reflux symptoms.
Read More

Frequently Asked Questions

7.5
Controls reflux effectively
5 people found this helpful
This product is a lifesaver for those suffering from gastroesophageal reflux. Although I initially tried Super Enzymes and later Pepsin HCL to see improvement, I still faced occasional issues, prompting me to increase the dosage. Now, I take one tablet of Jarrow Formulas L-Glutamine each morning and one on an empty stomach. After a week, I noticed that my gastroesophageal reflux was much better controlled, and increasing my coffee intake no longer triggers any reflux symptoms.
9
Significant heartburn drop
3 people found this helpful
My husband and I have noticed a considerable reduction in heartburn and acid reflux since we began taking L-Glutamine. Thankfully, we haven’t experienced any adverse side effects either!
6
Effective support
Alright. I took this for my reflux, and I found that this amino acid works more effectively when combined with other supportive herbs.
9
Eliminates reflux
17 people found this helpful
Jarrow Formulas L-Glutamine 1000 has been excellent for my heartburn and reflux. I was previously on acid blockers, which provided some relief, yet I still experienced heartburn and reflux. Following a nutritionist's advice, I began taking both L-Glutamine and PepZinGI, ultimately stopping the acid blockers. Now, I no longer suffer from reflux and rarely have heartburn. I take four L-Glutamine capsules each morning on an empty stomach and two PepZinGI tablets with food. I've noticed that L-Glutamine alone performs exceptionally well, as I forgot to take PepZinGI a couple of times without experiencing symptoms. Nonetheless, PepZinGI is necessary, as I faced some recurring symptoms after a week without it.
9
Definitely effective
I purchased this for my mother, who has long-lasting symptoms of reflux esophagitis. She takes this in conjunction with two enzymes and prescribed medications, and the results have been evidently effective.
8
Effectiveness of L-glutamine unclear
We examined a case report detailing the naturopathic management of functional dyspepsia, particularly focusing on a 25-year-old female graduate student experiencing several gastrointestinal issues such as bloating, epigastric pain, and reflux. While the report highlighted the use of L-glutamine along with other interventions, it did not provide specific data on how effective L-glutamine was on its own in alleviating reflux symptoms.

The patient underwent a treatment regimen that included an elimination diet and the use of apple cider vinegar alongside L-glutamine. Within a week of starting the treatment, the patient reported significant improvement in her symptoms. Notably, by the end of one month, she had resolved nearly all symptoms, with the exception of straining during bowel movements.

However, because L-glutamine was used in combination with other therapies, we cannot definitively assess its isolated impact on reflux symptoms. While the overall approach showed promise for symptom relief, the study’s design did not allow for a clear understanding of L-glutamine’s specific role in treating reflux.

References

  1. Pistoia JC, Chandler L. Naturopathic Approach to Functional Dyspepsia: A Case Report. Integr Med (Encinitas). 2021;20:32.
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