Last update
3/29/2026
Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
USERS' SCORE
Good
Based on 2 Reviews
8.6
Supplement Facts
Serving Size: 2 Capsules
Amount Per Serving
%DV
Aged Garlic Extract™†† Powder (bulb)
600 mg
**
Top Medical Research Studies
9
Garlic compounds reduce allergy symptoms
We explored the use of two compounds derived from garlic, N-benzyl-N-methyldecan-1-amine (BMDA) and its derivative, in addressing atopic dermatitis (AD) symptoms in mice. The study focused on whether these garlic-based treatments could alleviate skin lesions induced by a known irritant, 2,4-dinitrochlorobenzene (DNCB).
Our findings showed that topical application of BMDA and its derivative significantly reduced swelling, redness, and scratching associated with AD-like conditions. We noticed a remarkable decrease in skin inflammation and a reduction in the number of mast cells, which play a key role in allergic responses. Notably, the treatments also lowered IgE levels, a marker often related to allergic reactions, suggesting that these compounds could affect the underlying allergic response.
Furthermore, by analyzing skin samples, we found that the garlic-derived compounds decreased the levels of several inflammatory cytokines that typically drive allergic reactions. This extended to major inflammation-related signaling molecules, indicating that the treatment helped calm the overactive immune response often seen in allergic conditions like AD.
Overall, our research suggests that BMDA and DMMA have potential as novel treatments for managing inflammatory responses associated with allergies, particularly atopic dermatitis. This is exciting because it opens the door to new, plant-based approaches for allergy treatment while emphasizing the health benefits of garlic and its derivatives.
Our findings showed that topical application of BMDA and its derivative significantly reduced swelling, redness, and scratching associated with AD-like conditions. We noticed a remarkable decrease in skin inflammation and a reduction in the number of mast cells, which play a key role in allergic responses. Notably, the treatments also lowered IgE levels, a marker often related to allergic reactions, suggesting that these compounds could affect the underlying allergic response.
Furthermore, by analyzing skin samples, we found that the garlic-derived compounds decreased the levels of several inflammatory cytokines that typically drive allergic reactions. This extended to major inflammation-related signaling molecules, indicating that the treatment helped calm the overactive immune response often seen in allergic conditions like AD.
Overall, our research suggests that BMDA and DMMA have potential as novel treatments for managing inflammatory responses associated with allergies, particularly atopic dermatitis. This is exciting because it opens the door to new, plant-based approaches for allergy treatment while emphasizing the health benefits of garlic and its derivatives.
Read More
8
Garlic protein selectively enhances cellular immunity
Researchers tested garlic's ability to enhance immune responses related to allergies. They compared fresh garlic and commercial tablets, finding that both strengthened delayed-type hypersensitivity—a key immune reaction—with the best results at 20 mg/kg doses.
A special 14-kDa protein isolated from garlic proved even more effective than whole garlic extract. Tissue samples showed the protein triggered immune cell growth in the spleen and lymph nodes. However, garlic did not boost antibody production, suggesting it works through one specific immune pathway rather than broadly enhancing all immune functions.
A special 14-kDa protein isolated from garlic proved even more effective than whole garlic extract. Tissue samples showed the protein triggered immune cell growth in the spleen and lymph nodes. However, garlic did not boost antibody production, suggesting it works through one specific immune pathway rather than broadly enhancing all immune functions.
Read More
Most Useful Reviews
9
Profound improvement
26 people found this helpful
I have started and stopped this supplement three times and noticed a significant improvement in my allergies each time I resumed taking it.
Read More
7.5
Helps immune response
The quality is excellent, as it raises immunity effectively. This supplement also improves allergies and supports skin health, along with benefitting blood pressure.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8.5
- All Researches
9
Garlic compounds reduce allergy symptoms
We explored the use of two compounds derived from garlic, N-benzyl-N-methyldecan-1-amine (BMDA) and its derivative, in addressing atopic dermatitis (AD) symptoms in mice. The study focused on whether these garlic-based treatments could alleviate skin lesions induced by a known irritant, 2,4-dinitrochlorobenzene (DNCB).
Our findings showed that topical application of BMDA and its derivative significantly reduced swelling, redness, and scratching associated with AD-like conditions. We noticed a remarkable decrease in skin inflammation and a reduction in the number of mast cells, which play a key role in allergic responses. Notably, the treatments also lowered IgE levels, a marker often related to allergic reactions, suggesting that these compounds could affect the underlying allergic response.
Furthermore, by analyzing skin samples, we found that the garlic-derived compounds decreased the levels of several inflammatory cytokines that typically drive allergic reactions. This extended to major inflammation-related signaling molecules, indicating that the treatment helped calm the overactive immune response often seen in allergic conditions like AD.
Overall, our research suggests that BMDA and DMMA have potential as novel treatments for managing inflammatory responses associated with allergies, particularly atopic dermatitis. This is exciting because it opens the door to new, plant-based approaches for allergy treatment while emphasizing the health benefits of garlic and its derivatives.
Our findings showed that topical application of BMDA and its derivative significantly reduced swelling, redness, and scratching associated with AD-like conditions. We noticed a remarkable decrease in skin inflammation and a reduction in the number of mast cells, which play a key role in allergic responses. Notably, the treatments also lowered IgE levels, a marker often related to allergic reactions, suggesting that these compounds could affect the underlying allergic response.
Furthermore, by analyzing skin samples, we found that the garlic-derived compounds decreased the levels of several inflammatory cytokines that typically drive allergic reactions. This extended to major inflammation-related signaling molecules, indicating that the treatment helped calm the overactive immune response often seen in allergic conditions like AD.
Overall, our research suggests that BMDA and DMMA have potential as novel treatments for managing inflammatory responses associated with allergies, particularly atopic dermatitis. This is exciting because it opens the door to new, plant-based approaches for allergy treatment while emphasizing the health benefits of garlic and its derivatives.
Read More
8
Garlic protein selectively enhances cellular immunity
Researchers tested garlic's ability to enhance immune responses related to allergies. They compared fresh garlic and commercial tablets, finding that both strengthened delayed-type hypersensitivity—a key immune reaction—with the best results at 20 mg/kg doses.
A special 14-kDa protein isolated from garlic proved even more effective than whole garlic extract. Tissue samples showed the protein triggered immune cell growth in the spleen and lymph nodes. However, garlic did not boost antibody production, suggesting it works through one specific immune pathway rather than broadly enhancing all immune functions.
A special 14-kDa protein isolated from garlic proved even more effective than whole garlic extract. Tissue samples showed the protein triggered immune cell growth in the spleen and lymph nodes. However, garlic did not boost antibody production, suggesting it works through one specific immune pathway rather than broadly enhancing all immune functions.
Read More
User Reviews
USERS' SCORE
Good
Based on 2 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9
Profound improvement
26 people found this helpful
I have started and stopped this supplement three times and noticed a significant improvement in my allergies each time I resumed taking it.
Read More
7.5
Helps immune response
The quality is excellent, as it raises immunity effectively. This supplement also improves allergies and supports skin health, along with benefitting blood pressure.
Read More
Frequently Asked Questions
No FAQs are available for this product and symptom.
References
- Kim JE, Budluang P, Park J, Lee KH, Pakdeepromma S, et al. N-benzyl-N-methyldecan-1-amine, derived from garlic, and its derivative alleviate 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin lesions in mice. Sci Rep. 2024;14:6776. 10.1038/s41598-024-56496-2
- Ghazanfari T, Hassan ZM, Ebrahimi M. Immunomodulatory activity of a protein isolated from garlic extract on delayed type hypersensitivity. Int Immunopharmacol. 2002;2:1541. PubMed
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