Last update
3/11/2026
Reviewed By
Infographics
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Moderately Good
Based on 28 Reviews
7.8
Supplement Facts
Serving Size: 2 Vegetarian Capsules
Amount Per Serving
%DV
Thiamine (vitamin B1) (as thiamine HCl)
100 mg
8333%
Riboflavin (vitamin B2) (as riboflavin and riboflavin 5'-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
100 mg•
625%
Vitamin B6 (as pyridoxine HCl and pyridoxal 5' phosphate)
100 mg
5882%
Folate (as L-5-methyltetrahydrofolate calcium salt)
680 mcg○
170%
Vitamin B12 (as methylcobalamin)
300 mcg
12500%
Biotin
1000 mcg
3333%
Pantothenic acid (as D-calcium pantothenate)
500 mg
10000%
Calcium (as D-calcium pantothenate, dicalcium phosphate)
50 mg
4%
Inositol
100 mg
**
PABA (para-aminobenzoic acid)
50 mg
**
Top Medical Research Studies
9
We aimed to evaluate how a panthenol-enriched mask, specifically La Roche-Posay Mask Pro, performs in improving skin barriers for different types, such as dry sensitive, oily sensitive, and oily acne-prone skin.
Over 177 participants used the mask under guidance, and we measured factors like hydration, sebum content, and redness at multiple intervals.
The results showed significant improvements across all skin types, particularly for oily acne skin, which saw reductions in sebum and redness. Importantly, there were no adverse effects reported, indicating that this mask can be a trusty companion for those with various skin concerns.
Over 177 participants used the mask under guidance, and we measured factors like hydration, sebum content, and redness at multiple intervals.
The results showed significant improvements across all skin types, particularly for oily acne skin, which saw reductions in sebum and redness. Importantly, there were no adverse effects reported, indicating that this mask can be a trusty companion for those with various skin concerns.
Read More
7
A split-face study on 20 acne patients compared two treatments applied to opposite sides of the face. The right side received four intense pulsed light (IPL) sessions spaced two weeks apart, while the left side received topical nicotinamide 4% (vitamin B3) cream applied twice daily for two months.
Both treatments significantly improved inflammatory acne lesions. However, IPL delivered noticeably better results than the nicotinamide cream, with patients expressing greater satisfaction with the light-based approach. The findings suggest IPL is a safe and effective option for mild to moderate acne, particularly when other systemic treatments aren't suitable.
Both treatments significantly improved inflammatory acne lesions. However, IPL delivered noticeably better results than the nicotinamide cream, with patients expressing greater satisfaction with the light-based approach. The findings suggest IPL is a safe and effective option for mild to moderate acne, particularly when other systemic treatments aren't suitable.
Read More
Most Useful Reviews
9
Significantly cleared acne
60 people found this helpful
Excellent! It truly works. This isn't my first order of this complex. I appreciate its composition and the manufacturing company inspires confidence. I’ve seen the results – for instance, my 15-year-old has practically eliminated acne while taking this complex.
Read More
8
Visible skin improvement
14 people found this helpful
I purchased this as an alternative to beauty medication, taking one pill daily post-breakfast. I can’t be certain of its effect alone, as I'm using other supplements too, but my skin has noticeably improved. Sebum production has decreased, my face looks less shiny in the evenings, and my acne has reduced. I’ll definitely continue!
Read More
2
No effect noticed
13 people found this helpful
It's unfortunate that they changed the lid. I bought it to improve my acne skin, but it didn't have any effect. I drink it after dinner and don’t feel tired the next day, so I keep buying it. However, the change in the container lid since November is a downside.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
- All Researches
9
We aimed to evaluate how a panthenol-enriched mask, specifically La Roche-Posay Mask Pro, performs in improving skin barriers for different types, such as dry sensitive, oily sensitive, and oily acne-prone skin.
Over 177 participants used the mask under guidance, and we measured factors like hydration, sebum content, and redness at multiple intervals.
The results showed significant improvements across all skin types, particularly for oily acne skin, which saw reductions in sebum and redness. Importantly, there were no adverse effects reported, indicating that this mask can be a trusty companion for those with various skin concerns.
Over 177 participants used the mask under guidance, and we measured factors like hydration, sebum content, and redness at multiple intervals.
The results showed significant improvements across all skin types, particularly for oily acne skin, which saw reductions in sebum and redness. Importantly, there were no adverse effects reported, indicating that this mask can be a trusty companion for those with various skin concerns.
Read More
7
A split-face study on 20 acne patients compared two treatments applied to opposite sides of the face. The right side received four intense pulsed light (IPL) sessions spaced two weeks apart, while the left side received topical nicotinamide 4% (vitamin B3) cream applied twice daily for two months.
Both treatments significantly improved inflammatory acne lesions. However, IPL delivered noticeably better results than the nicotinamide cream, with patients expressing greater satisfaction with the light-based approach. The findings suggest IPL is a safe and effective option for mild to moderate acne, particularly when other systemic treatments aren't suitable.
Both treatments significantly improved inflammatory acne lesions. However, IPL delivered noticeably better results than the nicotinamide cream, with patients expressing greater satisfaction with the light-based approach. The findings suggest IPL is a safe and effective option for mild to moderate acne, particularly when other systemic treatments aren't suitable.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 28 Reviews
7.8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Significantly cleared acne
60 people found this helpful
Excellent! It truly works. This isn't my first order of this complex. I appreciate its composition and the manufacturing company inspires confidence. I’ve seen the results – for instance, my 15-year-old has practically eliminated acne while taking this complex.
Read More
8
Visible skin improvement
14 people found this helpful
I purchased this as an alternative to beauty medication, taking one pill daily post-breakfast. I can’t be certain of its effect alone, as I'm using other supplements too, but my skin has noticeably improved. Sebum production has decreased, my face looks less shiny in the evenings, and my acne has reduced. I’ll definitely continue!
Read More
2
No effect noticed
13 people found this helpful
It's unfortunate that they changed the lid. I bought it to improve my acne skin, but it didn't have any effect. I drink it after dinner and don’t feel tired the next day, so I keep buying it. However, the change in the container lid since November is a downside.
Read More
8
Effective acne treatment
11 people found this helpful
I bought this to help treat my son's acne. Vitamin B is known to control sebum secretion. His acne, which didn’t improve with only the dermatologist's cartilage, cleared rapidly when used alongside it! I also occasionally take it for mouth ulcers, and it seems to speed up healing.
Read More
7
Improved skin tone
9 people found this helpful
I have acne-prone skin, so I bought this to clear it up. My skin condition has improved, and surprisingly, my entire body feels toned since I started taking the second course. I haven’t changed my body cream, so I wonder if this supplement is making a difference. Previously, I used supplements with a whitening effect, but I’ve never felt results like this before. My complexion and yellowing issues have been resolved.
Read More
Frequently Asked Questions
8
Reduced pimple size
4 people found this helpful
I recently bought this as my stomatitis and acne weren't healing well! I take it after meals without experiencing any niacin flush. By the third day of taking it, my pimples had shrunk considerably! I think I will continue taking it to see how it progresses.
7
Improved skin tone
9 people found this helpful
I have acne-prone skin, so I bought this to clear it up. My skin condition has improved, and surprisingly, my entire body feels toned since I started taking the second course. I haven’t changed my body cream, so I wonder if this supplement is making a difference. Previously, I used supplements with a whitening effect, but I’ve never felt results like this before. My complexion and yellowing issues have been resolved.
8
Tremendous improvement
2 people found this helpful
I initially thought B vitamins came from diet, but when my skin became rough, I started taking one capsule daily. As a result, my skin condition has improved tremendously! I rarely experience acne now, and the stiffness of my skin has significantly decreased. I'm delighted!
8
Visible skin improvement
14 people found this helpful
I purchased this as an alternative to beauty medication, taking one pill daily post-breakfast. I can’t be certain of its effect alone, as I'm using other supplements too, but my skin has noticeably improved. Sebum production has decreased, my face looks less shiny in the evenings, and my acne has reduced. I’ll definitely continue!
7
Effective for acne
3 people found this helpful
My acne is improving quickly! I initially started taking this for rough skin and overall health. Upon researching, I found it has numerous vitamin benefits. I take two supplements after meals each night, and despite their size, I’m used to them. I’m also taking omega-3 and vitamins C and D to boost my immune system and wellness.
9
We aimed to evaluate how a panthenol-enriched mask, specifically La Roche-Posay Mask Pro, performs in improving skin barriers for different types, such as dry sensitive, oily sensitive, and oily acne-prone skin.
Over 177 participants used the mask under guidance, and we measured factors like hydration, sebum content, and redness at multiple intervals.
The results showed significant improvements across all skin types, particularly for oily acne skin, which saw reductions in sebum and redness. Importantly, there were no adverse effects reported, indicating that this mask can be a trusty companion for those with various skin concerns.
Over 177 participants used the mask under guidance, and we measured factors like hydration, sebum content, and redness at multiple intervals.
The results showed significant improvements across all skin types, particularly for oily acne skin, which saw reductions in sebum and redness. Importantly, there were no adverse effects reported, indicating that this mask can be a trusty companion for those with various skin concerns.
References
- Zhang X, Tao H, Deng Y, He X, Zhang Z, et al. Efficacy and safety of a panthenol-enriched mask for individuals with distinct impaired skin barrier subtypes. J Cosmet Dermatol. 2024;23:2109. 10.1111/jocd.16231
- Al-Sharnoby HA, Al-Bakary RH, Nassar SO, Mesbah RAM. The Efficacy of Intense Pulsed Light Versus Topical Nicotinamide 4% in Treatment of Acne Vulgaris. Photodermatol Photoimmunol Photomed. 2025;41:e70025. 10.1111/phpp.70025
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