Last update
6/22/2026
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Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
USERS' SCORE
Questionable
Based on 31 Reviews
5.8
Supplement Facts
Serving Size: 2 Vegetarian Capsules
Amount Per Serving
%DV
Thiamine (vitamin B1) (as thiamine HCl)
100 mg
8333%
Riboflavin (vitamin B2) (as riboflavin and riboflavin 5'-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
100 mg•
625%
Vitamin B6 (as pyridoxine HCl and pyridoxal 5' phosphate)
100 mg
5882%
Folate (as L-5-methyltetrahydrofolate calcium salt)
680 mcg○
170%
Vitamin B12 (as methylcobalamin)
300 mcg
12500%
Biotin
1000 mcg
3333%
Pantothenic acid (as D-calcium pantothenate)
500 mg
10000%
Calcium (as D-calcium pantothenate, dicalcium phosphate)
50 mg
4%
Inositol
100 mg
**
PABA (para-aminobenzoic acid)
50 mg
**
Top Medical Research Studies
8
We evaluated how D-Pinitol affects allergic rhinitis (AR) in a controlled study using mice.
By sensitizing BALB/c mice with ovalbumin (OVA), we created an AR model. After giving treatment groups various doses of pinitol or montelukast, we found that higher doses of pinitol significantly reduced symptoms like sneezing and nasal discharge.
Notably, it also balanced specific immune responses typically seen in allergies. However, montelukast showed clearer results in some areas, indicating that while pinitol is promising, more research is necessary.
By sensitizing BALB/c mice with ovalbumin (OVA), we created an AR model. After giving treatment groups various doses of pinitol or montelukast, we found that higher doses of pinitol significantly reduced symptoms like sneezing and nasal discharge.
Notably, it also balanced specific immune responses typically seen in allergies. However, montelukast showed clearer results in some areas, indicating that while pinitol is promising, more research is necessary.
Read More
Most Useful Reviews
0
Severe allergy reaction
6 people found this helpful
The allergy I experienced was terrible. I urge others to be cautious when trying it multiple times since symptoms included intense redness and itching all over my body.
Read More
0
Immediate allergy response
5 people found this helpful
This complex did not suit me; I developed an allergy just two hours after taking it. The packaging was small, and the taste neutral, but I cannot comment on its effectiveness.
Read More
0
Allergy to complex
5 people found this helpful
Wonderful! This is supposedly the best vitamin B complex, yet it did not suit me; I experienced allergies all over my body in the form of hives.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 1 Research
8
- All Researches
8
We evaluated how D-Pinitol affects allergic rhinitis (AR) in a controlled study using mice.
By sensitizing BALB/c mice with ovalbumin (OVA), we created an AR model. After giving treatment groups various doses of pinitol or montelukast, we found that higher doses of pinitol significantly reduced symptoms like sneezing and nasal discharge.
Notably, it also balanced specific immune responses typically seen in allergies. However, montelukast showed clearer results in some areas, indicating that while pinitol is promising, more research is necessary.
By sensitizing BALB/c mice with ovalbumin (OVA), we created an AR model. After giving treatment groups various doses of pinitol or montelukast, we found that higher doses of pinitol significantly reduced symptoms like sneezing and nasal discharge.
Notably, it also balanced specific immune responses typically seen in allergies. However, montelukast showed clearer results in some areas, indicating that while pinitol is promising, more research is necessary.
Read More
User Reviews
USERS' SCORE
Questionable
Based on 31 Reviews
5.8
- All Reviews
- Positive Reviews
- Negative Reviews
0
Severe allergy reaction
6 people found this helpful
The allergy I experienced was terrible. I urge others to be cautious when trying it multiple times since symptoms included intense redness and itching all over my body.
Read More
0
Immediate allergy response
5 people found this helpful
This complex did not suit me; I developed an allergy just two hours after taking it. The packaging was small, and the taste neutral, but I cannot comment on its effectiveness.
Read More
0
Allergy to complex
5 people found this helpful
Wonderful! This is supposedly the best vitamin B complex, yet it did not suit me; I experienced allergies all over my body in the form of hives.
Read More
0
Allergy symptoms
4 people found this helpful
After taking just one capsule instead of the recommended two, I experienced redness and itching on my face and neck, similar to an allergic reaction. I disposed of it immediately.
Read More
0
Itching problem
3 people found this helpful
I had to stop using it as my wife and I both experienced allergies. I normally have no allergies, but four days on this made my armpits very itchy, so I had to quit.
Read More
Frequently Asked Questions
0
Great allergy
1 people found this helpful
The allergy from this manufacturer was significant; even after taking magnesium powder, I experienced a severe allergic reaction.
0
Severe allergic reaction
3 people found this helpful
I generally don't suffer from allergies, but after taking one capsule, I experienced a terrible allergic reaction within half an hour. Despite this, the B vitamins seem to be effective.
0
Redness and burning
1 people found this helpful
After four days of taking this product, I experienced an uncomfortable allergy with red spots and burning skin, and I wouldn't recommend it for allergy sufferers.
9
No allergies noted
1 people found this helpful
After COVID, my doctor advised B vitamins. I experienced no allergies taking them, but I find one capsule daily sufficient for me.
0
Failed expectations
1 people found this helpful
This was a complete failure for me as I unexpectedly developed allergies to these B vitamins, despite needing them due to a folate cycle defect.
0
Severe allergy reaction
6 people found this helpful
The allergy I experienced was terrible. I urge others to be cautious when trying it multiple times since symptoms included intense redness and itching all over my body.
8
We evaluated how D-Pinitol affects allergic rhinitis (AR) in a controlled study using mice.
By sensitizing BALB/c mice with ovalbumin (OVA), we created an AR model. After giving treatment groups various doses of pinitol or montelukast, we found that higher doses of pinitol significantly reduced symptoms like sneezing and nasal discharge.
Notably, it also balanced specific immune responses typically seen in allergies. However, montelukast showed clearer results in some areas, indicating that while pinitol is promising, more research is necessary.
By sensitizing BALB/c mice with ovalbumin (OVA), we created an AR model. After giving treatment groups various doses of pinitol or montelukast, we found that higher doses of pinitol significantly reduced symptoms like sneezing and nasal discharge.
Notably, it also balanced specific immune responses typically seen in allergies. However, montelukast showed clearer results in some areas, indicating that while pinitol is promising, more research is necessary.
References
- You X, Sun X, Kong J, Tian J, Shi Y, et al. D-Pinitol Attenuated Ovalbumin-induced Allergic Rhinitis in Experimental Mice via Balancing Th1/Th2 Response. Iran J Allergy Asthma Immunol. 2021;20:672. 10.18502/ijaai.v20i6.8017
