SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8
USERS' SCORE
Good
Based on 27 Reviews
8.3
Supplement Facts
Serving Size: 2 Vegetarian Capsules
Amount Per Serving
%DV
Thiamine (vitamin B1) (as thiamine HCl)
100 mg
8333%
Riboflavin (vitamin B2) (as riboflavin and riboflavin 5'-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
100 mg•
625%
Vitamin B6 (as pyridoxine HCl and pyridoxal 5' phosphate)
100 mg
5882%
Folate (as L-5-methyltetrahydrofolate calcium salt)
680 mcg○
170%
Vitamin B12 (as methylcobalamin)
300 mcg
12500%
Biotin
1000 mcg
3333%
Pantothenic acid (as D-calcium pantothenate)
500 mg
10000%
Calcium (as D-calcium pantothenate, dicalcium phosphate)
50 mg
4%
Inositol
100 mg
**
PABA (para-aminobenzoic acid)
50 mg
**
Top Medical Research Studies
9
Vitamin B may alleviate depression symptoms
[Effects of Vitamin B on Behaviors, Brain Monoamine Neurotransmitters, and Brain-Derived Neurotrophic Factor in Depressive Rats].
Provides new insights on treatment.
Our investigation looked into how Vitamin B affects behavior and neurotransmitter levels in rats undergoing stress-induced depression.
We set up three groups: a control group, a stressed group, and a stressed group receiving Vitamin B.
The results showed that Vitamin B improved neurotransmitter levels and reduced anxiety and depression-like behaviors in the rats. This suggests that Vitamin B could be beneficial in improving symptoms of depression driven by stress.
We set up three groups: a control group, a stressed group, and a stressed group receiving Vitamin B.
The results showed that Vitamin B improved neurotransmitter levels and reduced anxiety and depression-like behaviors in the rats. This suggests that Vitamin B could be beneficial in improving symptoms of depression driven by stress.
Read More
8
Vitamin B6 intake linked to depression
Associations of Dietary Intake of Vitamin B6 and Plasma Pyridoxal 5'-Phosphate Level With Depression in US Adults: Findings From NHANES 2005-2010.
Relevance score indicates moderate significance.
This study examined how dietary vitamin B6 and plasma levels of pyridoxal 5’-phosphate relate to depression in US adults. We analyzed data from nearly 25,000 people over five years, revealing that those with the highest vitamin B6 intake and plasma levels experienced a lower risk of depression.
Although these results are promising and suggest the benefits of a vitamin B6-rich diet, we also noted that further randomized controlled trials are needed to better understand the effects of vitamin B6 supplementation on mood.
Although these results are promising and suggest the benefits of a vitamin B6-rich diet, we also noted that further randomized controlled trials are needed to better understand the effects of vitamin B6 supplementation on mood.
Read More
8
Niacin shows promise for depression
SIRT1/PARP-1/NLRP3 cascade as a potential target for niacin neuroprotective effect in lipopolysaccharide-induced depressive-like behavior in mice.
Study demonstrates niacin's effectiveness
We investigated how niacin (vitamin B3) impacts depression, particularly through a mouse model using lipopolysaccharide to induce depressive behaviors.
The study revealed that niacin significantly reduced signs of despair in mice, leading to more mobility in forced swimming tests.
It not only boosted important brain chemicals but also activated protective pathways that lessen neuroinflammation associated with depression.
Overall, the findings suggest that niacin could be a promising option for managing depression by addressing key neuroprotective mechanisms.
The study revealed that niacin significantly reduced signs of despair in mice, leading to more mobility in forced swimming tests.
It not only boosted important brain chemicals but also activated protective pathways that lessen neuroinflammation associated with depression.
Overall, the findings suggest that niacin could be a promising option for managing depression by addressing key neuroprotective mechanisms.
Read More
Most Useful Reviews
9.5
Significant health improvement
After a month of using this vitamin, I noticed a considerable improvement in my overall health. It specifically aided me in overcoming depression, which I had struggled with for a long time. If you seek a supplement that benefits not just your physical health but your overall well-being, I highly recommend this one.
Read More
8.8
Health maintenance
B-Complex vitamins are crucial in energy production and maintaining health. They alleviate migraine attacks, particularly B6, B9, and B12, and significantly reduce depression and anger, enhancing overall recovery and immunity.
Read More
9.5
Great formulation
This product delivers great value and has significantly improved my depression. I truly appreciate its formulation.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 12 Researches
8
- All Researches
9.5
Thiamine deficiency linked to depression
What can cause cancer patients to attempt suicide? Thiamine deficiency mimicking the symptoms of major depressive disorder.
High relevance due to treatment implications.
We explored a remarkable case of a 58-year-old cancer patient who exhibited depressive symptoms potentially linked to thiamine deficiency (TD). Initially suspected of having major depressive disorder, her condition transformed dramatically after receiving intravenous thiamine.
Within an hour of treatment, her distressing symptoms—palpitations, dyspnea, and suicidal thoughts—significantly improved. This observation underscores the importance of considering TD as a reversible cause when patients present with depression-like symptoms, especially in serious cases involving cancer.
Within an hour of treatment, her distressing symptoms—palpitations, dyspnea, and suicidal thoughts—significantly improved. This observation underscores the importance of considering TD as a reversible cause when patients present with depression-like symptoms, especially in serious cases involving cancer.
Read More
9
Vitamin B may alleviate depression symptoms
[Effects of Vitamin B on Behaviors, Brain Monoamine Neurotransmitters, and Brain-Derived Neurotrophic Factor in Depressive Rats].
Provides new insights on treatment.
Our investigation looked into how Vitamin B affects behavior and neurotransmitter levels in rats undergoing stress-induced depression.
We set up three groups: a control group, a stressed group, and a stressed group receiving Vitamin B.
The results showed that Vitamin B improved neurotransmitter levels and reduced anxiety and depression-like behaviors in the rats. This suggests that Vitamin B could be beneficial in improving symptoms of depression driven by stress.
We set up three groups: a control group, a stressed group, and a stressed group receiving Vitamin B.
The results showed that Vitamin B improved neurotransmitter levels and reduced anxiety and depression-like behaviors in the rats. This suggests that Vitamin B could be beneficial in improving symptoms of depression driven by stress.
Read More
8
Zinc complex shows antidepressant promise
Exploring Zn(II)-Acetyl l-carnitine complex for simultaneous management of depression, chronic pain, and neuroprotection.
High relevance for depression research
We explored the effects of a newly developed zinc-acetyl-l-carnitine complex on depression and neuroprotection. This innovative compound showed a remarkable 54% increase in antidepressant activity compared to standard acetyl-l-carnitine.
Additionally, it demonstrated the ability to alleviate pain and protect nerve cells against damage. While the results are promising, further studies are needed to fully understand its long-term effectiveness and safety for depression and related conditions.
Additionally, it demonstrated the ability to alleviate pain and protect nerve cells against damage. While the results are promising, further studies are needed to fully understand its long-term effectiveness and safety for depression and related conditions.
Read More
8
Methylfolate may enhance antidepressant effects
Effect of combination therapy of methylfolate with antidepressants in patients with depressive disorder.
Promising treatment strategy observed.
We explored whether combining antidepressants with low-dose methylfolate could improve outcomes for patients with depressive disorder. In this open-label trial, 44 participants received standard antidepressant treatment along with 800 µg of methylfolate daily for four weeks.
We used questionnaires to gauge depression levels throughout the study. The results suggested that this combination therapy might enhance treatment effectiveness compared to antidepressant monotherapy. Overall, it signals a promising avenue for those battling depression, pointing toward an approachable and potentially beneficial treatment strategy.
We used questionnaires to gauge depression levels throughout the study. The results suggested that this combination therapy might enhance treatment effectiveness compared to antidepressant monotherapy. Overall, it signals a promising avenue for those battling depression, pointing toward an approachable and potentially beneficial treatment strategy.
Read More
8
Vitamin B6 intake linked to depression
Associations of Dietary Intake of Vitamin B6 and Plasma Pyridoxal 5'-Phosphate Level With Depression in US Adults: Findings From NHANES 2005-2010.
Relevance score indicates moderate significance.
This study examined how dietary vitamin B6 and plasma levels of pyridoxal 5’-phosphate relate to depression in US adults. We analyzed data from nearly 25,000 people over five years, revealing that those with the highest vitamin B6 intake and plasma levels experienced a lower risk of depression.
Although these results are promising and suggest the benefits of a vitamin B6-rich diet, we also noted that further randomized controlled trials are needed to better understand the effects of vitamin B6 supplementation on mood.
Although these results are promising and suggest the benefits of a vitamin B6-rich diet, we also noted that further randomized controlled trials are needed to better understand the effects of vitamin B6 supplementation on mood.
Read More
User Reviews
USERS' SCORE
Good
Based on 27 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Significant health improvement
After a month of using this vitamin, I noticed a considerable improvement in my overall health. It specifically aided me in overcoming depression, which I had struggled with for a long time. If you seek a supplement that benefits not just your physical health but your overall well-being, I highly recommend this one.
Read More
8.8
Health maintenance
B-Complex vitamins are crucial in energy production and maintaining health. They alleviate migraine attacks, particularly B6, B9, and B12, and significantly reduce depression and anger, enhancing overall recovery and immunity.
9.5
Great formulation
This product delivers great value and has significantly improved my depression. I truly appreciate its formulation.
8.8
Lifts mental fog
This product works excellently without side effects. I suffer from Pyrrole disorder and need activated B6. When I run out, my energy plummets and I can barely stay awake. It significantly helps lift the mental fog associated with my depression.
10
Improves mood significantly
Excellent for improving mood, my mother uses it and it effectively relieves depression while helping her visualise things.
Frequently Asked Questions
No FAQs are available for this product and symptom.
