SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.6
USERS' SCORE
Good
Based on 12 Reviews
8.3
Supplement Facts
Serving Size: 2 Vegetarian Capsules
Amount Per Serving
%DV
Thiamine (vitamin B1) (as thiamine HCl)
100 mg
8333%
Riboflavin (vitamin B2) (as riboflavin and riboflavin 5'-phosphate)
75 mg
5769%
Niacin (as niacinamide and niacin)
100 mg•
625%
Vitamin B6 (as pyridoxine HCl and pyridoxal 5' phosphate)
100 mg
5882%
Folate (as L-5-methyltetrahydrofolate calcium salt)
680 mcg○
170%
Vitamin B12 (as methylcobalamin)
300 mcg
12500%
Biotin
1000 mcg
3333%
Pantothenic acid (as D-calcium pantothenate)
500 mg
10000%
Calcium (as D-calcium pantothenate, dicalcium phosphate)
50 mg
4%
Inositol
100 mg
**
PABA (para-aminobenzoic acid)
50 mg
**
Top Medical Research Studies
9
Myo-inositol aids diabetes management
Myo-inositol rescued insulin resistance and dyslipidemia in db/db mice.
High relevance for diabetes treatment
We explored how Myo-inositol (MI) might help manage diabetes by studying its effects in db/db mice, a common model for type 2 diabetes. Findings showed that MI reduced high blood sugar and insulin levels, and it even improved insulin resistance, much like metformin does.
Additionally, MI lowered high triglyceride and cholesterol levels, which can benefit overall heart health. Interestingly, while it reduced fat cell formation, it didn't help control obesity in these mice. Overall, MI shows promise as a supportive treatment for hyperglycemia and related issues in diabetes patients.
Additionally, MI lowered high triglyceride and cholesterol levels, which can benefit overall heart health. Interestingly, while it reduced fat cell formation, it didn't help control obesity in these mice. Overall, MI shows promise as a supportive treatment for hyperglycemia and related issues in diabetes patients.
Read More
7
Annona muricata aids diabetes treatment
Deciphering the mechanism of Annona muricata leaf extract in alloxan-nicotinamide-induced diabetic rat model with H-NMR-based metabolomics approach.
High relevance for diabetes research
We explored the antidiabetic properties of Annona muricata leaf extract using a metabolomics approach on diabetes-induced rats. The study involved administering two doses of the extract to evaluate its impacts on metabolic profiles over four weeks.
Remarkably, the lower dose showed significant benefits, lowering serum urea levels while exhibiting effects similar to metformin. We found that the extract positively influenced various metabolic pathways, confirming its traditional use for managing diabetes. Overall, the research highlights promising insights into how this natural treatment could aid in diabetes management.
Remarkably, the lower dose showed significant benefits, lowering serum urea levels while exhibiting effects similar to metformin. We found that the extract positively influenced various metabolic pathways, confirming its traditional use for managing diabetes. Overall, the research highlights promising insights into how this natural treatment could aid in diabetes management.
Read More
8
NR may prevent diabetic bone loss
The protection of nicotinamide riboside against diabetes mellitus-induced bone loss via OXPHOS.
High relevance for diabetes research
We explored how nicotinamide riboside (NR), a vitamin precursor to NAD, influences bone loss in type 2 diabetic mice. By administering NR to mice with diabetes induced by a high-fat diet and streptozotocin, we observed impressive results.
NR not only improved insulin resistance, but also enhanced bone quality and microarchitecture. Plus, it helped reduce bone resorption and positively influenced crucial signaling pathways related to bone health.
Overall, our findings suggest that NR has potential as a treatment for diabetes-related bone issues, but further studies are needed to solidify these results.
NR not only improved insulin resistance, but also enhanced bone quality and microarchitecture. Plus, it helped reduce bone resorption and positively influenced crucial signaling pathways related to bone health.
Overall, our findings suggest that NR has potential as a treatment for diabetes-related bone issues, but further studies are needed to solidify these results.
Read More
Most Useful Reviews
8.8
Nervous system enhancement
I found this product remarkable; it hasn't improved the pie at all ❤. It's one of the highest quality types. My father's condition, affected by diabetes, has worn him out; however, this has proved wonderful for his nervous system, and if he continues taking it, I believe his condition will significantly improve.
Read More
9.5
Protects nerve damage
Excellent for me, as I have diabetes and it protects against nerve damage after Allah.
Read More
8.8
Improved overall health
Since I started taking it, I've noticed a marked improvement in my health, especially as I have diabetes and have been experiencing severe hair loss and breakage. I've combined it with two biotin supplements from the same company, and I feel optimistic about the benefits.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 11 Researches
7.6
- All Researches
9
Thiamine treatment aids diabetes management
Thiamine-responsive megaloblastic anaemia in a young adult with acute pancytopenia.
High relevance due to genetics
We examined a rare condition known as thiamine-responsive megaloblastic anaemia (TRMA) in a young man with type 1 diabetes and unexplained pancytopenia. After thorough testing revealed genetic factors, we found that daily thiamine supplementation effectively resolved his anemia.
More importantly, this treatment not only improved his blood counts but also lowered his insulin needs. This highlights the significance of identifying genetic causes in young patients presenting with such symptoms.
More importantly, this treatment not only improved his blood counts but also lowered his insulin needs. This highlights the significance of identifying genetic causes in young patients presenting with such symptoms.
Read More
9
Myo-inositol aids diabetes management
Myo-inositol rescued insulin resistance and dyslipidemia in db/db mice.
High relevance for diabetes treatment
We explored how Myo-inositol (MI) might help manage diabetes by studying its effects in db/db mice, a common model for type 2 diabetes. Findings showed that MI reduced high blood sugar and insulin levels, and it even improved insulin resistance, much like metformin does.
Additionally, MI lowered high triglyceride and cholesterol levels, which can benefit overall heart health. Interestingly, while it reduced fat cell formation, it didn't help control obesity in these mice. Overall, MI shows promise as a supportive treatment for hyperglycemia and related issues in diabetes patients.
Additionally, MI lowered high triglyceride and cholesterol levels, which can benefit overall heart health. Interestingly, while it reduced fat cell formation, it didn't help control obesity in these mice. Overall, MI shows promise as a supportive treatment for hyperglycemia and related issues in diabetes patients.
Read More
8
NR may prevent diabetic bone loss
The protection of nicotinamide riboside against diabetes mellitus-induced bone loss via OXPHOS.
High relevance for diabetes research
We explored how nicotinamide riboside (NR), a vitamin precursor to NAD, influences bone loss in type 2 diabetic mice. By administering NR to mice with diabetes induced by a high-fat diet and streptozotocin, we observed impressive results.
NR not only improved insulin resistance, but also enhanced bone quality and microarchitecture. Plus, it helped reduce bone resorption and positively influenced crucial signaling pathways related to bone health.
Overall, our findings suggest that NR has potential as a treatment for diabetes-related bone issues, but further studies are needed to solidify these results.
NR not only improved insulin resistance, but also enhanced bone quality and microarchitecture. Plus, it helped reduce bone resorption and positively influenced crucial signaling pathways related to bone health.
Overall, our findings suggest that NR has potential as a treatment for diabetes-related bone issues, but further studies are needed to solidify these results.
Read More
8
D-pinitol shows insulin-secreting potential
The Glucose-Lowering Effect of and D-Pinitol: Studies on Insulin Secretion in INS-1 Cells and the Reduction of Blood Glucose in Diabetic Rats.
High relevance to diabetes management
We examined how ice plant extract and its active component, D-pinitol, influence insulin secretion and glucose levels in diabetic rats. The study found that both IPE and D-pinitol significantly boosted insulin secretion in rat insulin-secreting cells.
Additionally, these substances improved glucose tolerance and displayed positive effects on liver function and lipid profiles. Overall, the findings suggest that IPE and D-pinitol show promise as functional foods that could help manage diabetes.
Additionally, these substances improved glucose tolerance and displayed positive effects on liver function and lipid profiles. Overall, the findings suggest that IPE and D-pinitol show promise as functional foods that could help manage diabetes.
Read More
8
Thiamine disulfide shows promise for diabetes
Long term administration of thiamine disulfide improves FOXO1/PEPCK pathway in liver to reduce insulin resistance in type 1 diabetes rat model.
High relevance for diabetes treatment
We investigated whether thiamine disulfide (TD) can lower blood sugar and improve insulin resistance in rats with type 1 diabetes. By assigning rats to different treatment groups, we used various tests to measure blood sugar, insulin sensitivity, and gene expression related to diabetes.
Results showed that TD effectively reduced blood glucose levels and improved several metabolic markers. However, it didn't affect the expression of the Glut4 gene, which plays a role in glucose uptake. Overall, TD demonstrated potential as a diabetes treatment, particularly in reducing insulin resistance.
Results showed that TD effectively reduced blood glucose levels and improved several metabolic markers. However, it didn't affect the expression of the Glut4 gene, which plays a role in glucose uptake. Overall, TD demonstrated potential as a diabetes treatment, particularly in reducing insulin resistance.
Read More
User Reviews
USERS' SCORE
Good
Based on 12 Reviews
8.3
- All Reviews
- Positive Reviews
- Negative Reviews
8.8
Nervous system enhancement
I found this product remarkable; it hasn't improved the pie at all ❤. It's one of the highest quality types. My father's condition, affected by diabetes, has worn him out; however, this has proved wonderful for his nervous system, and if he continues taking it, I believe his condition will significantly improve.
Read More
9.5
Protects nerve damage
Excellent for me, as I have diabetes and it protects against nerve damage after Allah.
8.8
Improved overall health
Since I started taking it, I've noticed a marked improvement in my health, especially as I have diabetes and have been experiencing severe hair loss and breakage. I've combined it with two biotin supplements from the same company, and I feel optimistic about the benefits.
8.8
B vitamins necessity
I have bought this product more than once because most of the B vitamin doses are at 100, which are crucial for managing panic, depression, and obsessive behaviours, particularly for patients with type 2 diabetes who require high doses of these vitamins.
8.8
Nervous system support
Very good complex. We took it for my mother, as she has diabetes and requires this vitamin. B vitamins are pivotal for energy synthesis, the proper functioning of the central nervous system and brain, and are crucial for the circulatory and cardiovascular systems. A deficiency in B vitamins often affects mood and mental health, leading to emotions such as irritability or depression. Additionally, signs like insomnia, fatigue, and poor hair and skin condition might indicate insufficient B vitamin levels.
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Frequently Asked Questions
No FAQs are available for this product and symptom.
