SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.8
USERS' SCORE
Good
Based on 7 Reviews
8.5
Supplement Facts
Serving Size: 1 Vegetarian Capsule
Amount Per Serving
%DV
Vitamin E (as D-alpha tocopheryl succinate)
20.1 mg
134%
Selenium (as Se-Methyl L-Selenocysteine, L-selenomethionine (yeast-free), sodium selenite)
200 mcg
364%
Top Medical Research Studies
8
Selenium aids gestational diabetes management
Selenium Supplementation and Gestational Diabetes: A Randomised Controlled Trial.
High relevance for diabetes treatment
We explored whether selenium supplementation could improve blood glucose levels in pregnant women with gestational diabetes. In this randomized controlled trial conducted at an Istanbul university, women diagnosed with gestational diabetes received either diet alone or diet plus 200 µg of selenium daily for four weeks.
Findings showed that pregnant women had lower selenium levels compared to healthy counterparts. Those taking selenium experienced a more significant decrease in blood sugar levels than those on diet alone, indicating a beneficial effect of selenium on managing gestational diabetes.
Findings showed that pregnant women had lower selenium levels compared to healthy counterparts. Those taking selenium experienced a more significant decrease in blood sugar levels than those on diet alone, indicating a beneficial effect of selenium on managing gestational diabetes.
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9
Antidiabetic effects of selenium
Physicochemical properties, structural characterization, and antidiabetic activity of selenylated low molecular weight apple pectin in HFD/STZ-induced type 2 diabetic mice.
High relevance to diabetes treatment
We investigated the impact of a novel selenylated low molecular weight apple pectin on diabetes management. The study focused on mice induced with type 2 diabetes through a high-fat diet and streptozotocin treatment.
Our findings revealed that this modified pectin significantly improved several diabetic symptoms. It reduced weight loss, lower blood sugar levels, and oxidative stress, while also protecting organs like the liver and kidneys.
Additionally, we observed enhanced glucose tolerance and improvements in lipid metabolism and insulin sensitivity among the mice receiving the treatment. The selenylated apple pectin not only had a notable effect on glucose metabolism but also appeared to offer protective benefits against inflammation and tissue damage.
Our findings revealed that this modified pectin significantly improved several diabetic symptoms. It reduced weight loss, lower blood sugar levels, and oxidative stress, while also protecting organs like the liver and kidneys.
Additionally, we observed enhanced glucose tolerance and improvements in lipid metabolism and insulin sensitivity among the mice receiving the treatment. The selenylated apple pectin not only had a notable effect on glucose metabolism but also appeared to offer protective benefits against inflammation and tissue damage.
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9
Selenium polysaccharides aid diabetes management
Selenium polysaccharide form sweet corn cob mediated hypoglycemic effects in vitro and untargeted metabolomics study on type 2 diabetes.
Strong focus on diabetes treatment
We explored the effects of selenium polysaccharides derived from sweet corn cob on type 2 diabetes (T2D) through a combination of laboratory tests and animal studies. The goal was to determine how this unique compound could influence blood sugar levels in those dealing with T2D.
Our findings indicated that selenium polysaccharides help regulate enzymes that break down carbohydrates, specifically α-amylase and α-glucosidase, which play a significant role in digesting sugars. By inhibiting these enzymes, the compound appears to reduce sugar absorption into the bloodstream.
In animal models, we observed that selenium polysaccharides not only curbed blood sugar spikes but also significantly altered various metabolic pathways, impacting substances like adenine and others linked to energy and lipid metabolism. Additionally, when we compared selenium polysaccharides to a common diabetes medication, metformin, we found that the polysaccharides provided more effective metabolic interventions.
Overall, our study suggests that selenium-treated polysaccharides could play a meaningful role in managing T2D and reducing its complications while improving blood glucose levels.
Our findings indicated that selenium polysaccharides help regulate enzymes that break down carbohydrates, specifically α-amylase and α-glucosidase, which play a significant role in digesting sugars. By inhibiting these enzymes, the compound appears to reduce sugar absorption into the bloodstream.
In animal models, we observed that selenium polysaccharides not only curbed blood sugar spikes but also significantly altered various metabolic pathways, impacting substances like adenine and others linked to energy and lipid metabolism. Additionally, when we compared selenium polysaccharides to a common diabetes medication, metformin, we found that the polysaccharides provided more effective metabolic interventions.
Overall, our study suggests that selenium-treated polysaccharides could play a meaningful role in managing T2D and reducing its complications while improving blood glucose levels.
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Most Useful Reviews
9.5
Effective treatment
Excellent! This complex preparation is of suitable dosage and provides good results. I take it for diabetes and highly recommend it.
Read More
9.5
Trusted product
The manufacturer is reliable, and the capsules are small and easy to swallow. I purchased other products from this company to help manage diabetes. Everything works well together, and there have been no negative effects.
Read More
8
Improved health
Great product and quality. Thank you, iHerb, for providing such reliable products. Selenium is essential for thyroid function, and I purchased it for this reason. It's particularly important for those suffering from diabetes and cancer, acting as a vital antioxidant that may protect against heart disease. If you enjoy this comment, please like it. Thank you.
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Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.8
- All Researches
9.5
Selenium nanofibers enhance wound healing
Selenium-containing polyurethane nanofibers with MnO nanoparticles and gelsevirine promote diabetic wound healing by modulation of ROS and inflammation.
High relevance for diabetic wound healing
We explored how selenium-containing polyurethane nanofibers can aid in diabetic wound healing. The study developed unique nanofibers designed to tackle harmful reactive oxygen species (ROS) and inflammation, both of which impede recovery.
These nanofibers demonstrated excellent ability to reduce ROS levels, leading to remarkable healing results—showing up to 92% improvement within 14 days. Additionally, they maintained high cell viability, indicating safety. Overall, this innovative approach could significantly enhance treatment for diabetic wounds.
These nanofibers demonstrated excellent ability to reduce ROS levels, leading to remarkable healing results—showing up to 92% improvement within 14 days. Additionally, they maintained high cell viability, indicating safety. Overall, this innovative approach could significantly enhance treatment for diabetic wounds.
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9.5
Effective hydrogel for diabetic wounds
Influence of chitosan and hydroxyethyl cellulose modifications towards the design of cross-linked double networks hydrogel for diabetic wound healing.
Highly relevant to wound healing
We investigated the effectiveness of a new hydrogel designed for diabetic wound healing, made from oxidized hydroxyethyl cellulose (OHEC) and chitosan with selenium nanoparticles.
This hydrogel demonstrated impressive properties, including superior antioxidant and antibacterial abilities, which contribute to faster wound healing.
Our findings showed a remarkable 100% wound closure in laboratory tests within 12 hours and almost complete healing in animal models within 14 days.
Overall, this study highlights the hydrogel's multifunctional benefits, making it a promising option for treating chronic and infected wounds.
This hydrogel demonstrated impressive properties, including superior antioxidant and antibacterial abilities, which contribute to faster wound healing.
Our findings showed a remarkable 100% wound closure in laboratory tests within 12 hours and almost complete healing in animal models within 14 days.
Overall, this study highlights the hydrogel's multifunctional benefits, making it a promising option for treating chronic and infected wounds.
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9
Selenium's role in diabetes treatment
Nanometerizing Taxifolin Into Selenized Liposomes to Ameliorate Its Hypoglycemic Effect by Optimizing Drug Release and Bioavailability.
Limited understanding of selenium's effect
We sought to understand how selenium, when combined with taxifolin, might improve treatment options for diabetes mellitus. The focus was on creating selenized liposomes, or Tax-Se@LPs, that would enhance the delivery and effectiveness of taxifolin, a natural compound known for its potential health benefits.
Through a specialized manufacturing technique, we developed these nanometric liposomes and assessed their performance in preclinical settings. Our findings indicated that Tax-Se@LPs not only improved the absorption of taxifolin in the digestive system but also significantly reduced blood glucose levels in diabetic models. With a relative bioavailability of 216.65%, the selenized formulation demonstrated a more prolonged effect compared to other delivery methods.
Despite these promising results, our study did not isolate the effectiveness of selenium on its own. The benefits observed were largely attributed to the advanced delivery system rather than the selenium content alone. Therefore, while increased bioavailability and hypoglycemic effects are evident from using Tax-Se@LPs, the specific role that selenium plays in these outcomes needs further exploration for a clearer understanding.
Through a specialized manufacturing technique, we developed these nanometric liposomes and assessed their performance in preclinical settings. Our findings indicated that Tax-Se@LPs not only improved the absorption of taxifolin in the digestive system but also significantly reduced blood glucose levels in diabetic models. With a relative bioavailability of 216.65%, the selenized formulation demonstrated a more prolonged effect compared to other delivery methods.
Despite these promising results, our study did not isolate the effectiveness of selenium on its own. The benefits observed were largely attributed to the advanced delivery system rather than the selenium content alone. Therefore, while increased bioavailability and hypoglycemic effects are evident from using Tax-Se@LPs, the specific role that selenium plays in these outcomes needs further exploration for a clearer understanding.
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9
Selenium's Role in Diabetes Control
Molecular Observations on the Regulation of hIAPP Aggregation Process and Enhancement of Autophagy by the Short Peptide LPFYPN and Its Modified Peptides of Coix Seed Prolamins.
Assessment of peptide efficacy
We investigated how selenium-modified peptides affect the aggregation of the human islet amyloid polypeptide (hIAPP), which is known to have a role in diabetes. Our study focused on the active peptide derived from coix seed prolamins called LPFYPN (LP6) and its modified versions.
Through our experiments, we observed that both LP6 and its modified peptides, particularly the selenium-enhanced version, significantly inhibited the harmful aggregation of hIAPP. This aggregation is linked to the cytotoxic effects that can worsen diabetes conditions.
The findings showed that the selenium-modified peptide not only reduced these harmful aggregates but also helped to boost the body's autophagy processes—essentially improving how cells eliminate these damaging proteins. By doing so, it reduced cell toxicity and promoted healthier cell function.
Overall, our results suggest that selenium holds potential in developing new dietary approaches to manage type 2 diabetes and possibly other amyloid-related diseases. This could mean that including selenium-rich ingredients in our diet may provide valuable health benefits in tackling diabetes health challenges.
Through our experiments, we observed that both LP6 and its modified peptides, particularly the selenium-enhanced version, significantly inhibited the harmful aggregation of hIAPP. This aggregation is linked to the cytotoxic effects that can worsen diabetes conditions.
The findings showed that the selenium-modified peptide not only reduced these harmful aggregates but also helped to boost the body's autophagy processes—essentially improving how cells eliminate these damaging proteins. By doing so, it reduced cell toxicity and promoted healthier cell function.
Overall, our results suggest that selenium holds potential in developing new dietary approaches to manage type 2 diabetes and possibly other amyloid-related diseases. This could mean that including selenium-rich ingredients in our diet may provide valuable health benefits in tackling diabetes health challenges.
Read More
9
Antidiabetic effects of selenium
Physicochemical properties, structural characterization, and antidiabetic activity of selenylated low molecular weight apple pectin in HFD/STZ-induced type 2 diabetic mice.
High relevance to diabetes treatment
We investigated the impact of a novel selenylated low molecular weight apple pectin on diabetes management. The study focused on mice induced with type 2 diabetes through a high-fat diet and streptozotocin treatment.
Our findings revealed that this modified pectin significantly improved several diabetic symptoms. It reduced weight loss, lower blood sugar levels, and oxidative stress, while also protecting organs like the liver and kidneys.
Additionally, we observed enhanced glucose tolerance and improvements in lipid metabolism and insulin sensitivity among the mice receiving the treatment. The selenylated apple pectin not only had a notable effect on glucose metabolism but also appeared to offer protective benefits against inflammation and tissue damage.
Our findings revealed that this modified pectin significantly improved several diabetic symptoms. It reduced weight loss, lower blood sugar levels, and oxidative stress, while also protecting organs like the liver and kidneys.
Additionally, we observed enhanced glucose tolerance and improvements in lipid metabolism and insulin sensitivity among the mice receiving the treatment. The selenylated apple pectin not only had a notable effect on glucose metabolism but also appeared to offer protective benefits against inflammation and tissue damage.
Read More
User Reviews
USERS' SCORE
Good
Based on 7 Reviews
8.5
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Effective treatment
Excellent! This complex preparation is of suitable dosage and provides good results. I take it for diabetes and highly recommend it.
9.5
Trusted product
The manufacturer is reliable, and the capsules are small and easy to swallow. I purchased other products from this company to help manage diabetes. Everything works well together, and there have been no negative effects.
8
Improved health
Great product and quality. Thank you, iHerb, for providing such reliable products. Selenium is essential for thyroid function, and I purchased it for this reason. It's particularly important for those suffering from diabetes and cancer, acting as a vital antioxidant that may protect against heart disease. If you enjoy this comment, please like it. Thank you.
Read More
8.8
Boosted immunity
Daily health care can help prevent cancer and enhance immunity. Selenium is an essential trace element crucial for overall health. It plays a significant role in countering free radicals and can aid in regulating blood sugar levels, thus helping to prevent complications of diabetes. Additionally, selenium has a unique affinity for heavy metals and aids in detoxification.
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8.8
Restored pancreas
I bought it for my mother to help restore her pancreas due to her diabetes mellitus. I read that selenium helps restore pancreatic cells, which is crucial for her health. She takes it in courses with no side effects. Selenium also benefits the immune system, making it valuable in many health complexes.
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Frequently Asked Questions
No FAQs are available for this product and symptom.
