We conducted a pilot trial to explore the effectiveness of zinc acetate in treating chronic refractory cough, a condition that causes significant discomfort for many people. In this study, we compared zinc acetate against a placebo over a period of six weeks, with the aim of measuring improvements in quality of life and cough symptoms using several established questionnaires.
Our group included 34 participants who were primarily white females suffering from moderate to severe cough. Throughout the trial, we noted that those taking zinc acetate did experience a rise in serum zinc levels, which indicates that the treatment was effective in that regard. However, when assessing the overall impact on cough symptoms and quality of life, both the zinc and placebo groups showed improvements, but those improvements were minimal.
Importantly, the treatment effects observed did not reach the clinically meaningful thresholds that would suggest zinc acetate significantly benefits cough management. Therefore, we concluded that there is no substantial advantage to using zinc therapy over placebo for people dealing with chronic cough, and suggest that larger trials are unnecessary at this time.
Read More
9
Zinc therapy shows promise for cough
A Potential Novel Treatment for Chronic Cough in Long COVID Patients: Clearance of Epipharyngeal Residual SARS-CoV-2 Spike RNA by Epipharyngeal Abrasive Therapy.
We explored the effectiveness of Epipharyngeal Abrasive Therapy (EAT) in addressing chronic cough, particularly in the context of Long COVID. This treatment, prevalent in Japan, uses zinc chloride to reduce inflammation in the epipharyngeal mucosa. We followed a 21-year-old man whose chronic cough persisted for four months after a mild COVID-19 infection. Upon diagnosis, we identified chronic epipharyngitis as the culprit behind his ongoing cough.
The EAT involved weekly treatments for three months. We observed that this therapy not only cleared residual SARS-CoV-2 spike RNA from the epipharyngeal mucosa but also led to a decrease in inflammation and proinflammatory cytokines. While the application of zinc chloride was a significant part of the treatment, it was combined with other elements of EAT, making it challenging to isolate zinc's specific impact on cough relief.
Overall, we found that EAT could be a promising avenue for individuals suffering from chronic cough related to Long COVID, highlighting an innovative way to utilize zinc in managing this persistent symptom.
Read More
8
Zinc in mixed COVID treatment
Efficacy and Safety of Aspirin, Promethazine, and Micronutrients for Rapid Clinical Recovery in Mild to Moderate COVID-19 Patients: A Randomized Controlled Clinical Trial.
We conducted a rigorous randomized controlled trial to evaluate the effectiveness of an innovative treatment involving a combination of two tablets: one with Aspirin and Promethazine, and another packed with essential micronutrients like vitamin D3, C, B3, zinc, and selenium. Our aim was to determine how this combination affects the symptoms of mild to moderate COVID-19, particularly cough.
Our study included 260 patients and followed a strict methodology, comparing this new treatment to the standard clinical management recommended by the Indian Council of Medical Research. Over a treatment period of 10 days, we observed notable improvements in symptoms, including cough, myalgia, headache, and anosmia, among those who received the APMV2020 treatment alongside standard care.
While zinc was included in the treatment, this study does not isolate its effect on cough specifically since it was part of a comprehensive combination. However, our findings indicated that APMV2020 treatment led to a significant reduction in cough symptoms and inflammatory markers. This positions APMV2020 as a promising candidate for inclusion in COVID-19 management protocols, not only for rapid recovery but also for its potential long-term benefits in reducing complications associated with the virus.
Read More
Most Useful Reviews
9
Relieves choking cough
Large lozenges, effective for a pharyngeal or laryngeal sensation, should be absorbed slowly. They have been my salvation from a choking cough at night. I highly recommend them.
Read More
9
Quick relief
A magic tool! With a sore throat and cold, it works very quickly. I recommend it! No need for sugary cough drops anymore.
Read More
9
Immediate relief
This lozenge is extremely effective for coughs and works immediately, especially with NAC.
A Potential Novel Treatment for Chronic Cough in Long COVID Patients: Clearance of Epipharyngeal Residual SARS-CoV-2 Spike RNA by Epipharyngeal Abrasive Therapy.
We explored the effectiveness of Epipharyngeal Abrasive Therapy (EAT) in addressing chronic cough, particularly in the context of Long COVID. This treatment, prevalent in Japan, uses zinc chloride to reduce inflammation in the epipharyngeal mucosa. We followed a 21-year-old man whose chronic cough persisted for four months after a mild COVID-19 infection. Upon diagnosis, we identified chronic epipharyngitis as the culprit behind his ongoing cough.
The EAT involved weekly treatments for three months. We observed that this therapy not only cleared residual SARS-CoV-2 spike RNA from the epipharyngeal mucosa but also led to a decrease in inflammation and proinflammatory cytokines. While the application of zinc chloride was a significant part of the treatment, it was combined with other elements of EAT, making it challenging to isolate zinc's specific impact on cough relief.
Overall, we found that EAT could be a promising avenue for individuals suffering from chronic cough related to Long COVID, highlighting an innovative way to utilize zinc in managing this persistent symptom.
Read More
8
Zinc in mixed COVID treatment
Efficacy and Safety of Aspirin, Promethazine, and Micronutrients for Rapid Clinical Recovery in Mild to Moderate COVID-19 Patients: A Randomized Controlled Clinical Trial.
We conducted a rigorous randomized controlled trial to evaluate the effectiveness of an innovative treatment involving a combination of two tablets: one with Aspirin and Promethazine, and another packed with essential micronutrients like vitamin D3, C, B3, zinc, and selenium. Our aim was to determine how this combination affects the symptoms of mild to moderate COVID-19, particularly cough.
Our study included 260 patients and followed a strict methodology, comparing this new treatment to the standard clinical management recommended by the Indian Council of Medical Research. Over a treatment period of 10 days, we observed notable improvements in symptoms, including cough, myalgia, headache, and anosmia, among those who received the APMV2020 treatment alongside standard care.
While zinc was included in the treatment, this study does not isolate its effect on cough specifically since it was part of a comprehensive combination. However, our findings indicated that APMV2020 treatment led to a significant reduction in cough symptoms and inflammatory markers. This positions APMV2020 as a promising candidate for inclusion in COVID-19 management protocols, not only for rapid recovery but also for its potential long-term benefits in reducing complications associated with the virus.
Read More
2
Zinc acetate ineffective for cough
Efficacy and tolerability of zinc acetate for treatment of chronic refractory cough: pilot randomised futility trial.
We conducted a pilot trial to explore the effectiveness of zinc acetate in treating chronic refractory cough, a condition that causes significant discomfort for many people. In this study, we compared zinc acetate against a placebo over a period of six weeks, with the aim of measuring improvements in quality of life and cough symptoms using several established questionnaires.
Our group included 34 participants who were primarily white females suffering from moderate to severe cough. Throughout the trial, we noted that those taking zinc acetate did experience a rise in serum zinc levels, which indicates that the treatment was effective in that regard. However, when assessing the overall impact on cough symptoms and quality of life, both the zinc and placebo groups showed improvements, but those improvements were minimal.
Importantly, the treatment effects observed did not reach the clinically meaningful thresholds that would suggest zinc acetate significantly benefits cough management. Therefore, we concluded that there is no substantial advantage to using zinc therapy over placebo for people dealing with chronic cough, and suggest that larger trials are unnecessary at this time.
Read More
User Reviews
USERS' SCORE
Good
Based on 9 Reviews
8.3
All Reviews
Positive Reviews
Negative Reviews
9
Relieves choking cough
Large lozenges, effective for a pharyngeal or laryngeal sensation, should be absorbed slowly. They have been my salvation from a choking cough at night. I highly recommend them.
Read More
9
Quick relief
A magic tool! With a sore throat and cold, it works very quickly. I recommend it! No need for sugary cough drops anymore.
Read More
9
Immediate relief
This lozenge is extremely effective for coughs and works immediately, especially with NAC.
Read More
9
Cough relief
One lozenge helped with a cough that had tormented me all day. It dissolves quickly, tastes better than zinc with mint.
Read More
7.5
Zinc for cough
At the first signs of bronchitis, I always take lozenges with zinc which alleviate the cough, strengthen the body, and help the illness to recede.
Coughing is a reflex action that helps clear the airways of mucus, irritants, or foreign particles. It is a natural mechanism the body uses to protect itself and can be triggered by various factors, including infections, allergies, or environmental irritants. There are two main types of coughs: acute coughs, which typically last less than three weeks and often result from a cold or respiratory infection, and chronic coughs, which persist for more than eight weeks and may indicate a more serious underlying condition.
Coughs can also be classified as dry or productive. A dry cough does not produce mucus, while a productive cough does. Treatment options depend on the underlying cause; over-the-counter medications, home remedies, or medical intervention may be recommended based on the severity and duration of the cough. If a cough is persistent, accompanied by other symptoms like fever, shortness of breath, or chest pain, it’s advisable to seek medical advice for a proper diagnosis and treatment plan.
Zinc is a versatile metal known for its various applications in industry and health. It is a bluish-white metallic element represented by the symbol Zn and atomic number 30 on the periodic table. Zinc is primarily used for galvanizing steel to prevent rusting, in the manufacturing of alloys, and as a component in batteries. Additionally, zinc plays a crucial role in biological processes, making it an essential trace element in the human diet. It is involved in immune function, protein synthesis, wound healing, and DNA synthesis, highlighting its importance in maintaining overall health and well-being.
Zinc has garnered attention for its potential role in reducing the duration and severity of colds, which often include symptoms like cough. Some studies suggest that zinc may help by modulating the immune response and reducing inflammation in the throat and respiratory tract. While there are mixed results regarding its efficacy specifically for cough relief, it is commonly found in over-the-counter cold remedies. It’s important to note that more research is needed to confirm these benefits conclusively.
According to user reviews, many individuals report experiencing quick relief from cough symptoms after taking this supplement. Some users state that they notice results almost immediately after using the lozenges, especially for coughs related to throat irritation or cold symptoms. For example, one review highlights that the lozenge "works very quickly" for sore throats and cold Read Review, while another indicates effectiveness for coughs "immediately" Read Review.
Additionally, users frequently mention that even a single lozenge can provide substantial relief, with one reviewer noting that just one lozenge helped alleviate a persistent cough that had been troubling them all day Read Review. Overall, while individual experiences may vary, many users seem to find relief from cough symptoms quickly after administration of the product.
No, the supplement zinc acetate is not strongly supported by scientific research for treating cough. A pilot study evaluated its efficacy in managing chronic refractory cough, but while participants experienced an increase in serum zinc levels, the improvements in cough symptoms were minimal and did not reach clinically meaningful thresholds. The researchers concluded that there is no substantial advantage in using zinc therapy over placebo for chronic cough management [1].
In another context, zinc chloride was utilized in a novel treatment for chronic cough related to Long COVID. Although the treatment showed some promise, it was combined with other therapies, making it difficult to determine the specific impact of zinc on cough relief [2]. Furthermore, a study involving a combination therapy that included zinc also demonstrated effectiveness in improving cough symptoms, but again, it was part of a broader treatment and did not isolate zinc's effects [3]. Overall, while zinc may play a role in some cough treatments, current research does not provide strong evidence for its standalone efficacy in managing cough symptoms.
Users report a variety of improvements in their symptoms after using this lozenge. Many have found it beneficial for alleviating coughs, with one reviewer stating that it has been a "salvation from a choking cough at night" Read Review. Others have noted that it is especially effective for sore throats and cold-related discomfort, with one user describing it as a "magic tool" that works "very quickly" Read Review.
Furthermore, users often mention a rapid response to the lozenge, suggesting it can provide relief almost immediately for coughs Read Review and helps manage persistent symptoms throughout the day Read Review. Overall, while individual results may vary, these anecdotal experiences highlight a general consensus that the lozenge offers effective support against coughs and throat irritation.
According to user reviews, combining this supplement with other products can enhance its effectiveness in handling coughs. One reviewer highlights that this lozenge works immediately, especially when used alongside NAC (N-acetylcysteine), suggesting that the pairing might provide quicker relief for cough symptoms Read Review. Other users mention the benefits of including zinc, with one noting its effectiveness for coughs and mouth infections, as well as its role in relieving inflammation Read Review.
Additionally, there's evidence that using these lozenges in conjunction with other remedies can support recovery from respiratory ailments. One user points out that they take lozenges with zinc at the first signs of bronchitis to alleviate cough and strengthen their body Read Review. Collectively, these reviews indicate that users often find improved results when combining this lozenge with other supplements, particularly zinc and NAC, to effectively address cough symptoms.
Based on user reviews, there is a consensus that zinc lozenges can be effective for treating coughs, particularly when absorbed slowly to provide maximum relief. Users have noted their effectiveness in alleviating coughs associated with colds and infections, especially in soothing irritated throats Read Review. One reviewer mentioned that a single lozenge was able to help mitigate a persistent cough, indicating that for some, a lower dose might suffice Read Review.
Moreover, several users highlighted the importance of dosage timing and stomach condition, suggesting that zinc should not be taken on an empty stomach for optimal results Read Review. The feedback suggests that effective doses can lead to rapid relief from cough symptoms, while also contributing to overall immune support against colds Read Review. This indicates that while the right dose may vary among individuals, many find zinc lozenges to be a beneficial adjunct in cough treatment.
9
Quick relief
A magic tool! With a sore throat and cold, it works very quickly. I recommend it! No need for sugary cough drops anymore.
9
Immediate relief
This lozenge is extremely effective for coughs and works immediately, especially with NAC.
9
Cough relief
One lozenge helped with a cough that had tormented me all day. It dissolves quickly, tastes better than zinc with mint.
9
Relieves choking cough
Large lozenges, effective for a pharyngeal or laryngeal sensation, should be absorbed slowly. They have been my salvation from a choking cough at night. I highly recommend them.
7.5
Pleasant taste
Zinc is effective for coughs and mouth infections, disinfecting and relieving inflammation. Plus, the taste is pleasant.
7.5
Zinc for cough
At the first signs of bronchitis, I always take lozenges with zinc which alleviate the cough, strengthen the body, and help the illness to recede.
6
Effective for coughs
1 people found this helpful
Everyone notes how useful this drug is. I would advise against taking it on an empty stomach; otherwise, everything is fine! It helps with the initial symptoms of colds and coughs.
7.5
Immunity booster
This really helps improve your immunity, particularly against coughs and colds. It has a pleasant taste.
2
Zinc acetate ineffective for cough
Efficacy and tolerability of zinc acetate for treatment of chronic refractory cough: pilot randomised futility trial.
We conducted a pilot trial to explore the effectiveness of zinc acetate in treating chronic refractory cough, a condition that causes significant discomfort for many people. In this study, we compared zinc acetate against a placebo over a period of six weeks, with the aim of measuring improvements in quality of life and cough symptoms using several established questionnaires.
Our group included 34 participants who were primarily white females suffering from moderate to severe cough. Throughout the trial, we noted that those taking zinc acetate did experience a rise in serum zinc levels, which indicates that the treatment was effective in that regard. However, when assessing the overall impact on cough symptoms and quality of life, both the zinc and placebo groups showed improvements, but those improvements were minimal.
Importantly, the treatment effects observed did not reach the clinically meaningful thresholds that would suggest zinc acetate significantly benefits cough management. Therefore, we concluded that there is no substantial advantage to using zinc therapy over placebo for people dealing with chronic cough, and suggest that larger trials are unnecessary at this time.
9
Zinc therapy shows promise for cough
A Potential Novel Treatment for Chronic Cough in Long COVID Patients: Clearance of Epipharyngeal Residual SARS-CoV-2 Spike RNA by Epipharyngeal Abrasive Therapy.
We explored the effectiveness of Epipharyngeal Abrasive Therapy (EAT) in addressing chronic cough, particularly in the context of Long COVID. This treatment, prevalent in Japan, uses zinc chloride to reduce inflammation in the epipharyngeal mucosa. We followed a 21-year-old man whose chronic cough persisted for four months after a mild COVID-19 infection. Upon diagnosis, we identified chronic epipharyngitis as the culprit behind his ongoing cough.
The EAT involved weekly treatments for three months. We observed that this therapy not only cleared residual SARS-CoV-2 spike RNA from the epipharyngeal mucosa but also led to a decrease in inflammation and proinflammatory cytokines. While the application of zinc chloride was a significant part of the treatment, it was combined with other elements of EAT, making it challenging to isolate zinc's specific impact on cough relief.
Overall, we found that EAT could be a promising avenue for individuals suffering from chronic cough related to Long COVID, highlighting an innovative way to utilize zinc in managing this persistent symptom.
8
Zinc in mixed COVID treatment
Efficacy and Safety of Aspirin, Promethazine, and Micronutrients for Rapid Clinical Recovery in Mild to Moderate COVID-19 Patients: A Randomized Controlled Clinical Trial.
We conducted a rigorous randomized controlled trial to evaluate the effectiveness of an innovative treatment involving a combination of two tablets: one with Aspirin and Promethazine, and another packed with essential micronutrients like vitamin D3, C, B3, zinc, and selenium. Our aim was to determine how this combination affects the symptoms of mild to moderate COVID-19, particularly cough.
Our study included 260 patients and followed a strict methodology, comparing this new treatment to the standard clinical management recommended by the Indian Council of Medical Research. Over a treatment period of 10 days, we observed notable improvements in symptoms, including cough, myalgia, headache, and anosmia, among those who received the APMV2020 treatment alongside standard care.
While zinc was included in the treatment, this study does not isolate its effect on cough specifically since it was part of a comprehensive combination. However, our findings indicated that APMV2020 treatment led to a significant reduction in cough symptoms and inflammatory markers. This positions APMV2020 as a promising candidate for inclusion in COVID-19 management protocols, not only for rapid recovery but also for its potential long-term benefits in reducing complications associated with the virus.
References
Balasubramanian A, Holbrook JT, Canning BJ, Que LG, Castro M, et al. Efficacy and tolerability of zinc acetate for treatment of chronic refractory cough: pilot randomised futility trial. ERJ Open Res. 2023;9. doi:10.1183/23120541.00678-2022
Nishi K, Yoshimoto S, Tanaka T, Kimura S, Shinchi Y, et al. A Potential Novel Treatment for Chronic Cough in Long COVID Patients: Clearance of Epipharyngeal Residual SARS-CoV-2 Spike RNA by Epipharyngeal Abrasive Therapy. Cureus. 2023;15:e33421. doi:10.7759/cureus.33421
Kumar GS, Vadgaonkar A, Purunaik S, Shelatkar R, Vaidya VG, et al. Efficacy and Safety of Aspirin, Promethazine, and Micronutrients for Rapid Clinical Recovery in Mild to Moderate COVID-19 Patients: A Randomized Controlled Clinical Trial. Cureus. 2022;14:e25467. doi:10.7759/cureus.25467