In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.
We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.
The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
Read More
8
Euglena extract aids flu defense
Antiviral Activity and Underlying Action Mechanism of Euglena Extract against Influenza Virus.
We set out to uncover how Euglena extract might help combat influenza, particularly focusing on its components like zinc. This microalga, known for its nutritional benefits, has shown promise in alleviating flu symptoms in mice. Our investigation revealed that Euglena extract significantly inhibited various strains of the influenza virus, including those that resist traditional antiviral medications like oseltamivir and amantadine.
Through our research involving Madin-Darby canine kidney (MDCK) cells, we discovered that the extract doesn't disrupt the virus's replication cycle directly. Instead, it appears to bolster the host's defenses, which means it enhances our body's natural ability to fight off the virus. One of the key contributors to this antiviral activity seems to be the minerals present in the extract, particularly zinc.
Overall, this study suggests that Euglena extract could be a promising tool for flu prevention and treatment. Its potential benefits highlight the need for new approaches in tackling influenza, especially with the rise of drug-resistant strains. Our findings advocate for further exploration into how zinc and other components in Euglena can enhance our defenses against influenza.
Read More
8
Zinc's impact on flu symptoms
Zinc and Respiratory Viral Infections: Important Trace Element in Anti-viral Response and Immune Regulation.
We explored the role of zinc in supporting our immune system, especially in the fight against influenza. The studies suggest that zinc might be beneficial in reducing the viral load during flu infections.
Evidence shows that zinc can decrease the severity of symptoms associated with viral pneumonia, which is often a complication of influenza. Additionally, it appears to have a positive impact on the overall recovery process, potentially shortening the duration of illness.
We also noted that zinc may enhance the effectiveness of certain COVID-19 treatments, which gives further credence to its immune-boosting properties. However, the precise relationship between zinc levels and vaccine effectiveness, particularly for flu vaccines, remains complex and requires more investigation.
Ultimately, our understanding indicates that incorporating zinc into our regimen could provide an additional layer of defense against the flu virus while supporting our immune health.
Read More
Most Useful Reviews
9
Effective against flu
2 people found this helpful
This is the only brand that helps stop colds and flu. Life Extension offers typical high-quality supplements. This formula is uniquely effective in keeping the cold and flu at bay. Research reveals that other forms of Zinc aren’t as effective as Acetate, so it’s essential to use this effective option.
Read More
9
Effective for flu
1 people found this helpful
These are typically high-quality supplements from Life Extension. This formula is the only one that effectively keeps colds and flu at bay. The nuances matter - other forms of zinc are less effective than the Acetate variety. Do your research, and you’ll find this is the one that works.
Read More
9
Affordable flu remedy
An amazing product that is affordable and works perfectly well for cold and flu.
We investigated the potential of zinc in combination with herbal polyphenols and copper to reduce the infectivity of respiratory RNA viruses, including the flu. This study is particularly timely due to the ongoing challenges posed by viruses like SARS-CoV-2, highlighting the need for effective therapeutic solutions.
Zinc ions are known to play a role in modulating viral RNA replication, which makes them an appealing option for decreasing viral loads and infectivity. However, a significant challenge is that the natural concentration of zinc in our cells is often too low for effective results. To tackle this, we combined zinc picolinate, a form of zinc that’s easier for the body to absorb, with a range of flavonoids—natural compounds renowned for their antioxidant properties and existing antiviral effects.
We ensured that these combinations were safe by assessing their impact on cultured cells, confirming that they didn’t harm cell viability. When tested further, our results revealed an impressive 50-95% reduction in viral genome replication levels across a variety of respiratory RNA viruses, including the flu virus, which suggests that this combination therapy could be promising in the fight against such illnesses.
Overall, our findings highlight an innovative approach to treating viral infections that is non-toxic, derived from nature, and may remain effective against emerging viral strains.
Read More
8
Zinc mouthwash reduces flu symptoms
Efficacy of regular gargling with a cetylpyridinium chloride plus zinc containing mouthwash can reduce upper respiratory symptoms.
In our evaluation of how zinc can impact flu symptoms, we observed a study that examined the effects of gargling with an antimicrobial mouthwash containing zinc and cetylpyridinium chloride.
A total of 150 individuals participated, divided into two groups: one group followed a regular oral hygiene routine with fluoride toothpaste, while the other group followed the same routine but added gargling with a mouthwash containing 0.075% zinc.
The results revealed that regular gargling with this mouthwash helped reduce the frequency and severity of upper respiratory symptoms, with participants using the mouthwash showing a 21.5% lower frequency and 11% reduced severity in symptoms.
However, it's important to note that the study did not isolate the effects of zinc, leaving questions about the specific contributions of this mineral to the overall findings. Therefore, while we can see that the mouthwash appears beneficial, we cannot definitively attribute its effects solely to zinc.
Read More
8
Zinc treatment impacts flu virus entry
Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry.
In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.
We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.
The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
Read More
8
Euglena extract aids flu defense
Antiviral Activity and Underlying Action Mechanism of Euglena Extract against Influenza Virus.
We set out to uncover how Euglena extract might help combat influenza, particularly focusing on its components like zinc. This microalga, known for its nutritional benefits, has shown promise in alleviating flu symptoms in mice. Our investigation revealed that Euglena extract significantly inhibited various strains of the influenza virus, including those that resist traditional antiviral medications like oseltamivir and amantadine.
Through our research involving Madin-Darby canine kidney (MDCK) cells, we discovered that the extract doesn't disrupt the virus's replication cycle directly. Instead, it appears to bolster the host's defenses, which means it enhances our body's natural ability to fight off the virus. One of the key contributors to this antiviral activity seems to be the minerals present in the extract, particularly zinc.
Overall, this study suggests that Euglena extract could be a promising tool for flu prevention and treatment. Its potential benefits highlight the need for new approaches in tackling influenza, especially with the rise of drug-resistant strains. Our findings advocate for further exploration into how zinc and other components in Euglena can enhance our defenses against influenza.
Read More
8
Zinc's impact on flu symptoms
Zinc and Respiratory Viral Infections: Important Trace Element in Anti-viral Response and Immune Regulation.
We explored the role of zinc in supporting our immune system, especially in the fight against influenza. The studies suggest that zinc might be beneficial in reducing the viral load during flu infections.
Evidence shows that zinc can decrease the severity of symptoms associated with viral pneumonia, which is often a complication of influenza. Additionally, it appears to have a positive impact on the overall recovery process, potentially shortening the duration of illness.
We also noted that zinc may enhance the effectiveness of certain COVID-19 treatments, which gives further credence to its immune-boosting properties. However, the precise relationship between zinc levels and vaccine effectiveness, particularly for flu vaccines, remains complex and requires more investigation.
Ultimately, our understanding indicates that incorporating zinc into our regimen could provide an additional layer of defense against the flu virus while supporting our immune health.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 16 Reviews
7.9
All Reviews
Positive Reviews
Negative Reviews
9
Effective against flu
2 people found this helpful
This is the only brand that helps stop colds and flu. Life Extension offers typical high-quality supplements. This formula is uniquely effective in keeping the cold and flu at bay. Research reveals that other forms of Zinc aren’t as effective as Acetate, so it’s essential to use this effective option.
Read More
9
Effective for flu
1 people found this helpful
These are typically high-quality supplements from Life Extension. This formula is the only one that effectively keeps colds and flu at bay. The nuances matter - other forms of zinc are less effective than the Acetate variety. Do your research, and you’ll find this is the one that works.
Read More
9
Affordable flu remedy
An amazing product that is affordable and works perfectly well for cold and flu.
Read More
9
Personal flu relief
I believe it helped me and my daughter through our bad flu.
Read More
7.5
Small yet effective
The pill is small, but the dosage is right for boosting immunity when infected with the flu.
The flu, short for influenza, is a contagious respiratory illness caused by influenza viruses. It affects the nose, throat, and sometimes the lungs, leading to a range of symptoms that can vary in severity. Common symptoms include fever, chills, muscle aches, cough, congestion, runny nose, headaches, and fatigue. The flu can lead to serious complications, particularly in vulnerable populations such as young children, the elderly, pregnant women, and those with underlying health conditions.
The flu virus spreads primarily through respiratory droplets when an infected person coughs, sneezes, or talks. It can also be transmitted by touching surfaces contaminated with the virus and then touching one's face. Vaccination is the most effective way to prevent the flu, and the vaccine is typically updated annually to provide protection against the most common circulating strains. In addition to vaccination, practicing good hygiene, such as frequent handwashing and respiratory etiquette, can help minimize the risk of infection.
Zinc is a versatile metal known for its various applications in industry and health. It is a bluish-white metallic element represented by the symbol Zn and atomic number 30 on the periodic table. Zinc is primarily used for galvanizing steel to prevent rusting, in the manufacturing of alloys, and as a component in batteries. Additionally, zinc plays a crucial role in biological processes, making it an essential trace element in the human diet. It is involved in immune function, protein synthesis, wound healing, and DNA synthesis, highlighting its importance in maintaining overall health and well-being.
Zinc has been studied for its potential benefits in managing cold and flu symptoms, and there is some evidence to suggest that it may help reduce the severity and duration of these illnesses. Several clinical studies have indicated that zinc supplements can shorten the duration of cold symptoms if taken within the first 24 hours of their onset. While zinc may not necessarily prevent you from getting the flu, it could aid in alleviating symptoms and supporting your immune system during illness.
It's important to consider the appropriate dosage and consult with a healthcare provider before starting any supplementation, as excessive zinc intake can lead to adverse effects. Zinc lozenges and supplements can be helpful, but they should be part of a broader approach to flu prevention that includes vaccinations, maintaining a healthy lifestyle, and good hygiene practices. If you experience flu symptoms, it's always a good idea to consult a healthcare professional for tailored advice and treatment options.
Based on user reviews, the timeframe for seeing results from zinc lozenges during a flu illness varies. Many users report feeling the effects relatively quickly—often within a few hours to a day. For instance, one user mentions that these lozenges helped them and their daughter through a bad flu, suggesting a fast-acting nature Read Review. Similarly, others have noted that they typically take the lozenges at the first sign of illness to help boost immunity Read Review, indicating prompt use can lead to quicker relief.
However, while many users have reported quick benefits, it is essential to note that results can depend on individual health conditions and the timing of when the supplements are taken. Some users advocate regular use during cold and flu seasons for the best outcome Read Review. Overall, while effectiveness varies, most seem to appreciate swift results from regular usage during acute phases of illness.
The available research suggests that zinc plays a potential role in combating flu symptoms and enhancing immune response. For instance, a study on gargling with a mouthwash containing zinc showed a notable reduction in both the frequency and severity of upper respiratory symptoms related to the flu, although it did not isolate zinc as the sole contributing factor [1]. Similarly, other studies indicate that zinc may lower the expression of Cav1.2, a crucial molecule for the influenza virus to enter cells, implying that therapies involving zinc could limit flu infections [2].
Furthermore, a combination of zinc and natural compounds has demonstrated a significant reduction in viral genome replication for respiratory RNA viruses, including the flu, showcasing zinc’s potential as a therapeutic option [3]. Moreover, research on Euglena extract highlights zinc's role in bolstering host defenses against the influenza virus, particularly against resistant strains [4]. Lastly, zinc is shown to support the immune system and may help in reducing the severity of flu-related symptoms [5]. Overall, while evidence supports zinc's beneficial properties for flu prevention and treatment, more research is needed to understand its efficacy fully.
Based on user reviews, many have reported positive improvements in symptoms associated with colds and flu after using zinc lozenges. For instance, one user noted that the lozenges were instrumental in helping both them and their daughter through a bad flu, highlighting effective results during times of illness Read Review. Others have found these lozenges particularly beneficial in boosting immunity throughout the cold and flu seasons, suggesting consistent use offers a protective effect Read Review.
The lozenges have been praised for their palatable taste, with users appreciating the convenience and ease of consumption that comes with a time when sickness often makes swallowing pills challenging Read Review. Additionally, some individuals have reported experiencing fewer illnesses or milder symptoms when these lozenges are part of their regimen, indicating their potential effectiveness in supporting immunity Read Review. Nonetheless, it is important to note that results can vary widely from person to person, and efficacy may depend on individual health circumstances and the timing of use.
Based on user reviews, it appears that many individuals report positive experiences when combining zinc lozenges with other supplements to manage flu symptoms. Users frequently advocate for taking zinc alongside vitamin C, emphasizing that this combination enhances immune support, particularly at the onset of illness Read Review. Several reviewers noted the importance of maintaining immune health during the flu season, suggesting regular use of these lozenges not only for treating symptoms but also as a preventive measure for the entire family Read Review.
Additionally, some users have highlighted the effectiveness of zinc lozenges in conjunction with other health practices. For instance, a reviewer mentioned that their doctor recommended these lozenges as part of a comprehensive approach for adults during flu illnesses, indicating that the lozenges serve as an adjunct to overall health management Read Review. Overall, while users express satisfaction with the zinc lozenges' standalone benefits, the consensus leans toward combining them with other supplements like vitamin C for an even stronger defense against flu symptoms.
According to user reviews, the right dose of Zinc for treating flu seems to vary based on individual responses and preferences. Many users commend the effectiveness of zinc lozenges, particularly those containing Acetate, which are believed to be more effective than other forms like Zinc oxide (review id='47257490-2c96-494d-900e-c1bf3b015fdd' and review id='16441d55-a39b-4908-afd9-ac20e6ef805e'). Several reviews emphasize the importance of dosage; for example, one user noted that although each lozenge provides 18.75 mg, this may not be sufficient if someone is already suffering from the flu, suggesting one may need higher amounts for optimal effect Read Review.
Additionally, users seem to indicate that taking zinc more frequently can provide better immunity support during flu seasons. For instance, one reviewer mentioned using lozenges 3-4 times a week for immune boosts, particularly in winter Read Review. Others highlighted that the convenience and taste of these lozenges encourage consistent use during illness Read Review. Overall, user consensus points to regular intake of zinc, particularly in lozenge form, as beneficial for managing flu symptoms.
9
Personal flu relief
I believe it helped me and my daughter through our bad flu.
7.5
Essential for immunity
Zinc is vital for maintaining our immunity, especially at the first sign of illness during the cold and flu season. It is best taken with vitamin C, and zinc acts against copper and iron.
9
Prevention advice
Great citrus-flavoured zinc lozenges! They are ideal for protection and recovery from influenza and SARS. I take them every autumn-winter season for my whole family. They are very tasty and are essential during the cold season; I wholeheartedly advise everyone to purchase them!
7.5
Increased immunity
We’ve purchased these excellent quality lozenges before, and they really do help us get sick much less, particularly enhancing our immunity during the flu or COVID epidemics. The taste is sweet and sour with a hint of bitterness. The shape and size are small for easy dissolution. The results are consistently pleasing!
6
Easy zinc lozenges
Taste great! These lozenges are an easy way to take zinc; the flavour is delightful. I consume a couple of these a day when I have a cold or flu. They dissolve in the mouth or can be chewed, making them suitable for those who dislike swallowing capsules or tablets. They are good for immunity, so I take them daily.
7.5
Nice taste for flu
Great! Tastes nice. I use it for flu and it helps with my immune system.
4
Deficiency prevention
1 people found this helpful
Zinc oxide may not be the optimal form of zinc regarding results and absorption, but it can assist with deficiency prevention. Each lozenge contains 18.75mg, which might not suffice if you have existing issues or are already ill with the flu or a cold, yet it makes a good option for immune support. The taste is decent.
7.5
Winter flu aid
I always carry these lozenges in my purse and use them 3-4 times a week or whenever I seek an immune boost. The extra zinc helps during the winter flu season. Some zinc supplements upset my stomach, but the Life Extension lozenges taste great and do not cause me any issues. Great product!
8
Zinc mouthwash reduces flu symptoms
Efficacy of regular gargling with a cetylpyridinium chloride plus zinc containing mouthwash can reduce upper respiratory symptoms.
In our evaluation of how zinc can impact flu symptoms, we observed a study that examined the effects of gargling with an antimicrobial mouthwash containing zinc and cetylpyridinium chloride.
A total of 150 individuals participated, divided into two groups: one group followed a regular oral hygiene routine with fluoride toothpaste, while the other group followed the same routine but added gargling with a mouthwash containing 0.075% zinc.
The results revealed that regular gargling with this mouthwash helped reduce the frequency and severity of upper respiratory symptoms, with participants using the mouthwash showing a 21.5% lower frequency and 11% reduced severity in symptoms.
However, it's important to note that the study did not isolate the effects of zinc, leaving questions about the specific contributions of this mineral to the overall findings. Therefore, while we can see that the mouthwash appears beneficial, we cannot definitively attribute its effects solely to zinc.
8
Zinc treatment impacts flu virus entry
Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry.
In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.
We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.
The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
9
Zinc and flavonoids combat flu
Inhibition of Respiratory RNA Viruses by a Composition of Ionophoric Polyphenols with Metal Ions.
We investigated the potential of zinc in combination with herbal polyphenols and copper to reduce the infectivity of respiratory RNA viruses, including the flu. This study is particularly timely due to the ongoing challenges posed by viruses like SARS-CoV-2, highlighting the need for effective therapeutic solutions.
Zinc ions are known to play a role in modulating viral RNA replication, which makes them an appealing option for decreasing viral loads and infectivity. However, a significant challenge is that the natural concentration of zinc in our cells is often too low for effective results. To tackle this, we combined zinc picolinate, a form of zinc that’s easier for the body to absorb, with a range of flavonoids—natural compounds renowned for their antioxidant properties and existing antiviral effects.
We ensured that these combinations were safe by assessing their impact on cultured cells, confirming that they didn’t harm cell viability. When tested further, our results revealed an impressive 50-95% reduction in viral genome replication levels across a variety of respiratory RNA viruses, including the flu virus, which suggests that this combination therapy could be promising in the fight against such illnesses.
Overall, our findings highlight an innovative approach to treating viral infections that is non-toxic, derived from nature, and may remain effective against emerging viral strains.
8
Euglena extract aids flu defense
Antiviral Activity and Underlying Action Mechanism of Euglena Extract against Influenza Virus.
We set out to uncover how Euglena extract might help combat influenza, particularly focusing on its components like zinc. This microalga, known for its nutritional benefits, has shown promise in alleviating flu symptoms in mice. Our investigation revealed that Euglena extract significantly inhibited various strains of the influenza virus, including those that resist traditional antiviral medications like oseltamivir and amantadine.
Through our research involving Madin-Darby canine kidney (MDCK) cells, we discovered that the extract doesn't disrupt the virus's replication cycle directly. Instead, it appears to bolster the host's defenses, which means it enhances our body's natural ability to fight off the virus. One of the key contributors to this antiviral activity seems to be the minerals present in the extract, particularly zinc.
Overall, this study suggests that Euglena extract could be a promising tool for flu prevention and treatment. Its potential benefits highlight the need for new approaches in tackling influenza, especially with the rise of drug-resistant strains. Our findings advocate for further exploration into how zinc and other components in Euglena can enhance our defenses against influenza.
8
Zinc's impact on flu symptoms
Zinc and Respiratory Viral Infections: Important Trace Element in Anti-viral Response and Immune Regulation.
We explored the role of zinc in supporting our immune system, especially in the fight against influenza. The studies suggest that zinc might be beneficial in reducing the viral load during flu infections.
Evidence shows that zinc can decrease the severity of symptoms associated with viral pneumonia, which is often a complication of influenza. Additionally, it appears to have a positive impact on the overall recovery process, potentially shortening the duration of illness.
We also noted that zinc may enhance the effectiveness of certain COVID-19 treatments, which gives further credence to its immune-boosting properties. However, the precise relationship between zinc levels and vaccine effectiveness, particularly for flu vaccines, remains complex and requires more investigation.
Ultimately, our understanding indicates that incorporating zinc into our regimen could provide an additional layer of defense against the flu virus while supporting our immune health.
References
Muniz FWMG, Casarin M, Pola NM, Rösing CK, Silveira TMD, et al. Efficacy of regular gargling with a cetylpyridinium chloride plus zinc containing mouthwash can reduce upper respiratory symptoms. PLoS One. 2025;20:e0316807. doi:10.1371/journal.pone.0316807
Nishi K, Yoshimoto S, Nishi S, Nishi T, Nishi R, et al. Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry. In Vivo. 2022;36:2357. doi:10.21873/invivo.12967
Kreiser T, Zaguri D, Sachdeva S, Zamostiano R, Mograbi J, et al. Inhibition of Respiratory RNA Viruses by a Composition of Ionophoric Polyphenols with Metal Ions. Pharmaceuticals (Basel). 2022;15. doi:10.3390/ph15030377
Nakashima A, Horio Y, Suzuki K, Isegawa Y. Antiviral Activity and Underlying Action Mechanism of Euglena Extract against Influenza Virus. Nutrients. 2021;13. doi:10.3390/nu13113911
Sadeghsoltani F, Mohammadzadeh I, Safari MM, Hassanpour P, Izadpanah M, et al. Zinc and Respiratory Viral Infections: Important Trace Element in Anti-viral Response and Immune Regulation. Biol Trace Elem Res. 2022;200:2556. doi:10.1007/s12011-021-02859-z