Overview

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.2
USERS' SCORE
Moderately Good
Based on 16 Reviews
7.9
Supplement Facts
Serving Size: 1 Vegetarian Lozenge
Amount Per Serving
%DV
Zinc (as zinc oxide, gluconate)
18.75 mg
170%

Top Medical Research Studies

8
Zinc treatment impacts flu virus entry
In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.

We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.

The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
Read More
8
Euglena extract aids flu defense
We set out to uncover how Euglena extract might help combat influenza, particularly focusing on its components like zinc. This microalga, known for its nutritional benefits, has shown promise in alleviating flu symptoms in mice. Our investigation revealed that Euglena extract significantly inhibited various strains of the influenza virus, including those that resist traditional antiviral medications like oseltamivir and amantadine.

Through our research involving Madin-Darby canine kidney (MDCK) cells, we discovered that the extract doesn't disrupt the virus's replication cycle directly. Instead, it appears to bolster the host's defenses, which means it enhances our body's natural ability to fight off the virus. One of the key contributors to this antiviral activity seems to be the minerals present in the extract, particularly zinc.

Overall, this study suggests that Euglena extract could be a promising tool for flu prevention and treatment. Its potential benefits highlight the need for new approaches in tackling influenza, especially with the rise of drug-resistant strains. Our findings advocate for further exploration into how zinc and other components in Euglena can enhance our defenses against influenza.
Read More
We explored the role of zinc in supporting our immune system, especially in the fight against influenza. The studies suggest that zinc might be beneficial in reducing the viral load during flu infections.

Evidence shows that zinc can decrease the severity of symptoms associated with viral pneumonia, which is often a complication of influenza. Additionally, it appears to have a positive impact on the overall recovery process, potentially shortening the duration of illness.

We also noted that zinc may enhance the effectiveness of certain COVID-19 treatments, which gives further credence to its immune-boosting properties. However, the precise relationship between zinc levels and vaccine effectiveness, particularly for flu vaccines, remains complex and requires more investigation.

Ultimately, our understanding indicates that incorporating zinc into our regimen could provide an additional layer of defense against the flu virus while supporting our immune health.
Read More

Most Useful Reviews

9
Effective against flu
2 people found this helpful
This is the only brand that helps stop colds and flu. Life Extension offers typical high-quality supplements. This formula is uniquely effective in keeping the cold and flu at bay. Research reveals that other forms of Zinc aren’t as effective as Acetate, so it’s essential to use this effective option.
Read More
9
Effective for flu
1 people found this helpful
These are typically high-quality supplements from Life Extension. This formula is the only one that effectively keeps colds and flu at bay. The nuances matter - other forms of zinc are less effective than the Acetate variety. Do your research, and you’ll find this is the one that works.
Read More
9
Affordable flu remedy
An amazing product that is affordable and works perfectly well for cold and flu.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 5 Researches
8.2
  • All Researches
We investigated the potential of zinc in combination with herbal polyphenols and copper to reduce the infectivity of respiratory RNA viruses, including the flu. This study is particularly timely due to the ongoing challenges posed by viruses like SARS-CoV-2, highlighting the need for effective therapeutic solutions.

Zinc ions are known to play a role in modulating viral RNA replication, which makes them an appealing option for decreasing viral loads and infectivity. However, a significant challenge is that the natural concentration of zinc in our cells is often too low for effective results. To tackle this, we combined zinc picolinate, a form of zinc that’s easier for the body to absorb, with a range of flavonoids—natural compounds renowned for their antioxidant properties and existing antiviral effects.

We ensured that these combinations were safe by assessing their impact on cultured cells, confirming that they didn’t harm cell viability. When tested further, our results revealed an impressive 50-95% reduction in viral genome replication levels across a variety of respiratory RNA viruses, including the flu virus, which suggests that this combination therapy could be promising in the fight against such illnesses.

Overall, our findings highlight an innovative approach to treating viral infections that is non-toxic, derived from nature, and may remain effective against emerging viral strains.
Read More
In our evaluation of how zinc can impact flu symptoms, we observed a study that examined the effects of gargling with an antimicrobial mouthwash containing zinc and cetylpyridinium chloride.

A total of 150 individuals participated, divided into two groups: one group followed a regular oral hygiene routine with fluoride toothpaste, while the other group followed the same routine but added gargling with a mouthwash containing 0.075% zinc.

The results revealed that regular gargling with this mouthwash helped reduce the frequency and severity of upper respiratory symptoms, with participants using the mouthwash showing a 21.5% lower frequency and 11% reduced severity in symptoms.

However, it's important to note that the study did not isolate the effects of zinc, leaving questions about the specific contributions of this mineral to the overall findings. Therefore, while we can see that the mouthwash appears beneficial, we cannot definitively attribute its effects solely to zinc.
Read More
8
Zinc treatment impacts flu virus entry
In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.

We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.

The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
Read More
8
Euglena extract aids flu defense
We set out to uncover how Euglena extract might help combat influenza, particularly focusing on its components like zinc. This microalga, known for its nutritional benefits, has shown promise in alleviating flu symptoms in mice. Our investigation revealed that Euglena extract significantly inhibited various strains of the influenza virus, including those that resist traditional antiviral medications like oseltamivir and amantadine.

Through our research involving Madin-Darby canine kidney (MDCK) cells, we discovered that the extract doesn't disrupt the virus's replication cycle directly. Instead, it appears to bolster the host's defenses, which means it enhances our body's natural ability to fight off the virus. One of the key contributors to this antiviral activity seems to be the minerals present in the extract, particularly zinc.

Overall, this study suggests that Euglena extract could be a promising tool for flu prevention and treatment. Its potential benefits highlight the need for new approaches in tackling influenza, especially with the rise of drug-resistant strains. Our findings advocate for further exploration into how zinc and other components in Euglena can enhance our defenses against influenza.
Read More
We explored the role of zinc in supporting our immune system, especially in the fight against influenza. The studies suggest that zinc might be beneficial in reducing the viral load during flu infections.

Evidence shows that zinc can decrease the severity of symptoms associated with viral pneumonia, which is often a complication of influenza. Additionally, it appears to have a positive impact on the overall recovery process, potentially shortening the duration of illness.

We also noted that zinc may enhance the effectiveness of certain COVID-19 treatments, which gives further credence to its immune-boosting properties. However, the precise relationship between zinc levels and vaccine effectiveness, particularly for flu vaccines, remains complex and requires more investigation.

Ultimately, our understanding indicates that incorporating zinc into our regimen could provide an additional layer of defense against the flu virus while supporting our immune health.
Read More

User Reviews

USERS' SCORE
Moderately Good
Based on 16 Reviews
7.9
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Effective against flu
2 people found this helpful
This is the only brand that helps stop colds and flu. Life Extension offers typical high-quality supplements. This formula is uniquely effective in keeping the cold and flu at bay. Research reveals that other forms of Zinc aren’t as effective as Acetate, so it’s essential to use this effective option.
Read More
9
Effective for flu
1 people found this helpful
These are typically high-quality supplements from Life Extension. This formula is the only one that effectively keeps colds and flu at bay. The nuances matter - other forms of zinc are less effective than the Acetate variety. Do your research, and you’ll find this is the one that works.
Read More
9
Affordable flu remedy
An amazing product that is affordable and works perfectly well for cold and flu.
Read More
9
Personal flu relief
I believe it helped me and my daughter through our bad flu.
Read More
7.5
Small yet effective
The pill is small, but the dosage is right for boosting immunity when infected with the flu.
Read More

Frequently Asked Questions

9
Personal flu relief
I believe it helped me and my daughter through our bad flu.
7.5
Essential for immunity
Zinc is vital for maintaining our immunity, especially at the first sign of illness during the cold and flu season. It is best taken with vitamin C, and zinc acts against copper and iron.
9
Prevention advice
Great citrus-flavoured zinc lozenges! They are ideal for protection and recovery from influenza and SARS. I take them every autumn-winter season for my whole family. They are very tasty and are essential during the cold season; I wholeheartedly advise everyone to purchase them!
7.5
Increased immunity
We’ve purchased these excellent quality lozenges before, and they really do help us get sick much less, particularly enhancing our immunity during the flu or COVID epidemics. The taste is sweet and sour with a hint of bitterness. The shape and size are small for easy dissolution. The results are consistently pleasing!
6
Easy zinc lozenges
Taste great! These lozenges are an easy way to take zinc; the flavour is delightful. I consume a couple of these a day when I have a cold or flu. They dissolve in the mouth or can be chewed, making them suitable for those who dislike swallowing capsules or tablets. They are good for immunity, so I take them daily.
7.5
Nice taste for flu
Great! Tastes nice. I use it for flu and it helps with my immune system.
4
Deficiency prevention
1 people found this helpful
Zinc oxide may not be the optimal form of zinc regarding results and absorption, but it can assist with deficiency prevention. Each lozenge contains 18.75mg, which might not suffice if you have existing issues or are already ill with the flu or a cold, yet it makes a good option for immune support. The taste is decent.
7.5
Winter flu aid
I always carry these lozenges in my purse and use them 3-4 times a week or whenever I seek an immune boost. The extra zinc helps during the winter flu season. Some zinc supplements upset my stomach, but the Life Extension lozenges taste great and do not cause me any issues. Great product!
In our evaluation of how zinc can impact flu symptoms, we observed a study that examined the effects of gargling with an antimicrobial mouthwash containing zinc and cetylpyridinium chloride.

A total of 150 individuals participated, divided into two groups: one group followed a regular oral hygiene routine with fluoride toothpaste, while the other group followed the same routine but added gargling with a mouthwash containing 0.075% zinc.

The results revealed that regular gargling with this mouthwash helped reduce the frequency and severity of upper respiratory symptoms, with participants using the mouthwash showing a 21.5% lower frequency and 11% reduced severity in symptoms.

However, it's important to note that the study did not isolate the effects of zinc, leaving questions about the specific contributions of this mineral to the overall findings. Therefore, while we can see that the mouthwash appears beneficial, we cannot definitively attribute its effects solely to zinc.
8
Zinc treatment impacts flu virus entry
In our study, we examined how epipharyngeal abrasive therapy (EAT), which includes the use of zinc chloride, affects the expression of a key molecule known as Cav1.2. This molecule is essential for the influenza virus to enter cells, making it a crucial target in flu prevention strategies.

We compared two groups of patients: those who received EAT and those who did not. Our findings revealed that the levels of Cav1.2 were significantly lower in the EAT group, at a striking 4.19 times less than in the non-treated group. This suggests that the squamous metaplasia induced by EAT—which is a process of changing the epithelium—could be a beneficial approach to limiting flu infections.

The results of the study highlight zinc's potential indirect role in flu prevention by remarking on its contribution to lowering the expression of a critical receptor for the virus. Although we didn't isolate the effects of zinc alone, the findings indicate that treatments involving zinc, like EAT, may offer a straightforward way to help limit the impact of influenza.
We investigated the potential of zinc in combination with herbal polyphenols and copper to reduce the infectivity of respiratory RNA viruses, including the flu. This study is particularly timely due to the ongoing challenges posed by viruses like SARS-CoV-2, highlighting the need for effective therapeutic solutions.

Zinc ions are known to play a role in modulating viral RNA replication, which makes them an appealing option for decreasing viral loads and infectivity. However, a significant challenge is that the natural concentration of zinc in our cells is often too low for effective results. To tackle this, we combined zinc picolinate, a form of zinc that’s easier for the body to absorb, with a range of flavonoids—natural compounds renowned for their antioxidant properties and existing antiviral effects.

We ensured that these combinations were safe by assessing their impact on cultured cells, confirming that they didn’t harm cell viability. When tested further, our results revealed an impressive 50-95% reduction in viral genome replication levels across a variety of respiratory RNA viruses, including the flu virus, which suggests that this combination therapy could be promising in the fight against such illnesses.

Overall, our findings highlight an innovative approach to treating viral infections that is non-toxic, derived from nature, and may remain effective against emerging viral strains.
8
Euglena extract aids flu defense
We set out to uncover how Euglena extract might help combat influenza, particularly focusing on its components like zinc. This microalga, known for its nutritional benefits, has shown promise in alleviating flu symptoms in mice. Our investigation revealed that Euglena extract significantly inhibited various strains of the influenza virus, including those that resist traditional antiviral medications like oseltamivir and amantadine.

Through our research involving Madin-Darby canine kidney (MDCK) cells, we discovered that the extract doesn't disrupt the virus's replication cycle directly. Instead, it appears to bolster the host's defenses, which means it enhances our body's natural ability to fight off the virus. One of the key contributors to this antiviral activity seems to be the minerals present in the extract, particularly zinc.

Overall, this study suggests that Euglena extract could be a promising tool for flu prevention and treatment. Its potential benefits highlight the need for new approaches in tackling influenza, especially with the rise of drug-resistant strains. Our findings advocate for further exploration into how zinc and other components in Euglena can enhance our defenses against influenza.
We explored the role of zinc in supporting our immune system, especially in the fight against influenza. The studies suggest that zinc might be beneficial in reducing the viral load during flu infections.

Evidence shows that zinc can decrease the severity of symptoms associated with viral pneumonia, which is often a complication of influenza. Additionally, it appears to have a positive impact on the overall recovery process, potentially shortening the duration of illness.

We also noted that zinc may enhance the effectiveness of certain COVID-19 treatments, which gives further credence to its immune-boosting properties. However, the precise relationship between zinc levels and vaccine effectiveness, particularly for flu vaccines, remains complex and requires more investigation.

Ultimately, our understanding indicates that incorporating zinc into our regimen could provide an additional layer of defense against the flu virus while supporting our immune health.

References

  1. Muniz FWMG, Casarin M, Pola NM, Rösing CK, Silveira TMD, et al. Efficacy of regular gargling with a cetylpyridinium chloride plus zinc containing mouthwash can reduce upper respiratory symptoms. PLoS One. 2025;20:e0316807. doi:10.1371/journal.pone.0316807
  2. Nishi K, Yoshimoto S, Nishi S, Nishi T, Nishi R, et al. Epipharyngeal Abrasive Therapy Down-regulates the Expression of Cav1.2: A Key Molecule in Influenza Virus Entry. In Vivo. 2022;36:2357. doi:10.21873/invivo.12967
  3. Kreiser T, Zaguri D, Sachdeva S, Zamostiano R, Mograbi J, et al. Inhibition of Respiratory RNA Viruses by a Composition of Ionophoric Polyphenols with Metal Ions. Pharmaceuticals (Basel). 2022;15. doi:10.3390/ph15030377
  4. Nakashima A, Horio Y, Suzuki K, Isegawa Y. Antiviral Activity and Underlying Action Mechanism of Euglena Extract against Influenza Virus. Nutrients. 2021;13. doi:10.3390/nu13113911
  5. Sadeghsoltani F, Mohammadzadeh I, Safari MM, Hassanpour P, Izadpanah M, et al. Zinc and Respiratory Viral Infections: Important Trace Element in Anti-viral Response and Immune Regulation. Biol Trace Elem Res. 2022;200:2556. doi:10.1007/s12011-021-02859-z
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