Reviewed By
Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8.4
USERS' SCORE
Good
Based on 17 Reviews
8
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
Vitamin D3 (as cholecalciferol)
125 mcg
625%
Vitamin K activity from:Vitamin K1 (as phytonadione)Vitamin K2 (as menaquinone-4)Vitamin K2 (as trans menaquinone-7)
2,100 mcg1,000 mcg1,000 mcg100 mcg
1,750%
Iodine [from Sea-Iodine™ Complex Blend (organic kelp and bladderwrack extracts, potassium iodide)]
1,000 mcg
667%
Top Medical Research Studies
9
Vitamin D derivatives enhance bone health
We looked into the potential effects of vitamin D3, particularly its derivatives, on osteoporosis. Recent research highlights how modifications to the A-ring of 1α,25-dihydroxyvitamin D can enhance its binding to the vitamin D receptor. This change not only boosts the vitamin's effectiveness but also helps it resist breakdown in the body, making it stay active for longer periods.
One standout example is a derivative known as AH-1, which demonstrated significant benefits for bone health in an osteoporosis model using ovariectomized rats. When given at a low dosage, AH-1 outperformed natural vitamin D, suggesting a promising path for improving osteoporosis treatment.
We also noted that while traditional vitamin D has its benefits, these newly developed analogs could lead to treatments that target osteoporosis more effectively, providing options without the side effects commonly associated with vitamin D therapy. This research emphasizes the importance of vitamin D derivatives as we seek better solutions for managing bone health.
One standout example is a derivative known as AH-1, which demonstrated significant benefits for bone health in an osteoporosis model using ovariectomized rats. When given at a low dosage, AH-1 outperformed natural vitamin D, suggesting a promising path for improving osteoporosis treatment.
We also noted that while traditional vitamin D has its benefits, these newly developed analogs could lead to treatments that target osteoporosis more effectively, providing options without the side effects commonly associated with vitamin D therapy. This research emphasizes the importance of vitamin D derivatives as we seek better solutions for managing bone health.
Read More
9
We explored how Nano Vitamin D3 influences osteoporosis, particularly in the context of treatments involving anastrozole, a medication often used in cancer therapy. In our study, we observed the effects of Nano Vitamin D3 compared to selenium nanoparticles in female albino rats.
The research involved categorizing 28 rats into four groups, with one group receiving just anastrozole, while the other groups were treated with either selenium nanoparticles or Nano Vitamin D3 alongside anastrozole. After four weeks of treatment, we looked closely at the rats' mandibular bones to see how these treatments affected bone health.
Our findings indicated that both Selenium nanoparticles and Nano Vitamin D3 showed improvements in bone structure and cell health compared to the animals taking only anastrozole. The rats in the treatment groups demonstrated more newly formed collagen and healthier osteoblasts—cells that play a crucial role in bone formation. While we focused heavily on comparing these two approaches to therapy, the results confirmed that using Nano Vitamin D3 can be beneficial for combating osteoporosis exacerbated by anastrozole.
The research involved categorizing 28 rats into four groups, with one group receiving just anastrozole, while the other groups were treated with either selenium nanoparticles or Nano Vitamin D3 alongside anastrozole. After four weeks of treatment, we looked closely at the rats' mandibular bones to see how these treatments affected bone health.
Our findings indicated that both Selenium nanoparticles and Nano Vitamin D3 showed improvements in bone structure and cell health compared to the animals taking only anastrozole. The rats in the treatment groups demonstrated more newly formed collagen and healthier osteoblasts—cells that play a crucial role in bone formation. While we focused heavily on comparing these two approaches to therapy, the results confirmed that using Nano Vitamin D3 can be beneficial for combating osteoporosis exacerbated by anastrozole.
Read More
9
We investigated the effects of vitamin D3 supplementation during pregnancy on offspring's bone mineral density (BMD) as they grow. In the MAVIDOS study, pregnant women with low levels of vitamin D were given either a daily dose of 1000 IU of cholecalciferol (vitamin D3) or a placebo from their second trimester until delivery.
After the children reached ages 6 to 7, we assessed their bone health using advanced scanning techniques. The results revealed that those children whose mothers had received vitamin D3 supplementation exhibited higher BMD compared to those whose mothers received the placebo. This suggests that supplementing pregnant women with vitamin D3 could be a valuable public health strategy for improving bone health in children.
Even though this study focused on childhood, it reflects broader implications for how vitamin D3 might help in preventing conditions like osteoporosis later in life.
After the children reached ages 6 to 7, we assessed their bone health using advanced scanning techniques. The results revealed that those children whose mothers had received vitamin D3 supplementation exhibited higher BMD compared to those whose mothers received the placebo. This suggests that supplementing pregnant women with vitamin D3 could be a valuable public health strategy for improving bone health in children.
Even though this study focused on childhood, it reflects broader implications for how vitamin D3 might help in preventing conditions like osteoporosis later in life.
Read More
Most Useful Reviews
9
Visible changes
6 people found this helpful
My son has osteoporosis and blood clotting issues. Within days of taking this supplement, bleeding decreased significantly, and joint pain improved, reducing the need for painkillers. The small capsules are easy to take, and the price is very reasonable for such quick results.
Read More
9
Improved immunity
1 people found this helpful
I suffer from severe vitamin D deficiency, which has weakened my immunity and caused osteoporosis. I chose this product for its quality and safe ingredients. The dosage is suitable for daily use, and it's effective with a pleasant taste. Remember about 20 minutes of sunlight exposure.
Read More
9
Recovery support
Having suffered from COVID, I also deal with osteoporosis and hypothyroidism. This vitamin complex supports calcium absorption and boosts my immune system. I trust this brand entirely.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 14 Researches
8.4
- All Researches
9.5
We looked into the effects of vitamin D3 on osteoporosis management, particularly in relation to glucocorticoid-induced complications. In a recent case involving an 85-year-old patient with IgG4-related disease, vitamin D3 was used alongside prednisone and azathioprine. The goal was to prevent bone density loss often seen with steroid treatments.
Our focus on this case revealed that vitamin D3 played an essential role in supporting the patient’s bone health. This addition helped mitigate some side effects of long-term steroid use, specifically protecting against osteoporosis, while the patient experienced significant improvements in their orbital symptoms.
Over the course of treatment, the patient showed remarkable recovery in just 24 hours, along with a complete resolution of issues related to their eye condition over the following year. While direct data on vitamin D3's standalone effectiveness isn't highlighted, its use in this context underscores a possible beneficial role in osteoporosis prevention when combined with corticosteroids.
Our focus on this case revealed that vitamin D3 played an essential role in supporting the patient’s bone health. This addition helped mitigate some side effects of long-term steroid use, specifically protecting against osteoporosis, while the patient experienced significant improvements in their orbital symptoms.
Over the course of treatment, the patient showed remarkable recovery in just 24 hours, along with a complete resolution of issues related to their eye condition over the following year. While direct data on vitamin D3's standalone effectiveness isn't highlighted, its use in this context underscores a possible beneficial role in osteoporosis prevention when combined with corticosteroids.
Read More
9
Vitamin D derivatives enhance bone health
We looked into the potential effects of vitamin D3, particularly its derivatives, on osteoporosis. Recent research highlights how modifications to the A-ring of 1α,25-dihydroxyvitamin D can enhance its binding to the vitamin D receptor. This change not only boosts the vitamin's effectiveness but also helps it resist breakdown in the body, making it stay active for longer periods.
One standout example is a derivative known as AH-1, which demonstrated significant benefits for bone health in an osteoporosis model using ovariectomized rats. When given at a low dosage, AH-1 outperformed natural vitamin D, suggesting a promising path for improving osteoporosis treatment.
We also noted that while traditional vitamin D has its benefits, these newly developed analogs could lead to treatments that target osteoporosis more effectively, providing options without the side effects commonly associated with vitamin D therapy. This research emphasizes the importance of vitamin D derivatives as we seek better solutions for managing bone health.
One standout example is a derivative known as AH-1, which demonstrated significant benefits for bone health in an osteoporosis model using ovariectomized rats. When given at a low dosage, AH-1 outperformed natural vitamin D, suggesting a promising path for improving osteoporosis treatment.
We also noted that while traditional vitamin D has its benefits, these newly developed analogs could lead to treatments that target osteoporosis more effectively, providing options without the side effects commonly associated with vitamin D therapy. This research emphasizes the importance of vitamin D derivatives as we seek better solutions for managing bone health.
Read More
9
We explored how Nano Vitamin D3 influences osteoporosis, particularly in the context of treatments involving anastrozole, a medication often used in cancer therapy. In our study, we observed the effects of Nano Vitamin D3 compared to selenium nanoparticles in female albino rats.
The research involved categorizing 28 rats into four groups, with one group receiving just anastrozole, while the other groups were treated with either selenium nanoparticles or Nano Vitamin D3 alongside anastrozole. After four weeks of treatment, we looked closely at the rats' mandibular bones to see how these treatments affected bone health.
Our findings indicated that both Selenium nanoparticles and Nano Vitamin D3 showed improvements in bone structure and cell health compared to the animals taking only anastrozole. The rats in the treatment groups demonstrated more newly formed collagen and healthier osteoblasts—cells that play a crucial role in bone formation. While we focused heavily on comparing these two approaches to therapy, the results confirmed that using Nano Vitamin D3 can be beneficial for combating osteoporosis exacerbated by anastrozole.
The research involved categorizing 28 rats into four groups, with one group receiving just anastrozole, while the other groups were treated with either selenium nanoparticles or Nano Vitamin D3 alongside anastrozole. After four weeks of treatment, we looked closely at the rats' mandibular bones to see how these treatments affected bone health.
Our findings indicated that both Selenium nanoparticles and Nano Vitamin D3 showed improvements in bone structure and cell health compared to the animals taking only anastrozole. The rats in the treatment groups demonstrated more newly formed collagen and healthier osteoblasts—cells that play a crucial role in bone formation. While we focused heavily on comparing these two approaches to therapy, the results confirmed that using Nano Vitamin D3 can be beneficial for combating osteoporosis exacerbated by anastrozole.
Read More
9
We investigated the effects of vitamin D3 supplementation during pregnancy on offspring's bone mineral density (BMD) as they grow. In the MAVIDOS study, pregnant women with low levels of vitamin D were given either a daily dose of 1000 IU of cholecalciferol (vitamin D3) or a placebo from their second trimester until delivery.
After the children reached ages 6 to 7, we assessed their bone health using advanced scanning techniques. The results revealed that those children whose mothers had received vitamin D3 supplementation exhibited higher BMD compared to those whose mothers received the placebo. This suggests that supplementing pregnant women with vitamin D3 could be a valuable public health strategy for improving bone health in children.
Even though this study focused on childhood, it reflects broader implications for how vitamin D3 might help in preventing conditions like osteoporosis later in life.
After the children reached ages 6 to 7, we assessed their bone health using advanced scanning techniques. The results revealed that those children whose mothers had received vitamin D3 supplementation exhibited higher BMD compared to those whose mothers received the placebo. This suggests that supplementing pregnant women with vitamin D3 could be a valuable public health strategy for improving bone health in children.
Even though this study focused on childhood, it reflects broader implications for how vitamin D3 might help in preventing conditions like osteoporosis later in life.
Read More
9
Calcium and Vitamin D3 boost bone health
We conducted a comprehensive study to assess the effectiveness and safety of a daily regimen of calcium 600 mg combined with cholecalciferol (vitamin D3) 2000 IU in treating vitamin D deficiency, particularly in the context of osteoporosis. Our research included 302 adults who took these orodispersible tablets for at least 24 weeks.
The results showed that this combination therapy successfully increased serum levels of 25-hydroxivitamin D, an essential marker of vitamin D status. Notably, patients suffering from vitamin D deficiency experienced significant improvement in their vitamin D levels, reaching an optimal range conducive to better bone health.
We also observed that while the treatment led to improved vitamin D status, there were no significant adverse events reported, making it a safe option for long-term management of vitamin D deficiency and osteoporosis. Additionally, we found that reducing secondary hyperparathyroidism, a condition often associated with low vitamin D, was another positive outcome of this treatment.
Overall, the magnitude of increase in vitamin D levels directly correlated with the severity of the deficiency, indicating that those most in need benefited the most. Our study emphasizes the importance of addressing vitamin D deficiency, especially for individuals at risk of osteoporosis, without any notable burden of side effects.
The results showed that this combination therapy successfully increased serum levels of 25-hydroxivitamin D, an essential marker of vitamin D status. Notably, patients suffering from vitamin D deficiency experienced significant improvement in their vitamin D levels, reaching an optimal range conducive to better bone health.
We also observed that while the treatment led to improved vitamin D status, there were no significant adverse events reported, making it a safe option for long-term management of vitamin D deficiency and osteoporosis. Additionally, we found that reducing secondary hyperparathyroidism, a condition often associated with low vitamin D, was another positive outcome of this treatment.
Overall, the magnitude of increase in vitamin D levels directly correlated with the severity of the deficiency, indicating that those most in need benefited the most. Our study emphasizes the importance of addressing vitamin D deficiency, especially for individuals at risk of osteoporosis, without any notable burden of side effects.
Read More
User Reviews
USERS' SCORE
Good
Based on 17 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Visible changes
6 people found this helpful
My son has osteoporosis and blood clotting issues. Within days of taking this supplement, bleeding decreased significantly, and joint pain improved, reducing the need for painkillers. The small capsules are easy to take, and the price is very reasonable for such quick results.
Read More
9
Improved immunity
1 people found this helpful
I suffer from severe vitamin D deficiency, which has weakened my immunity and caused osteoporosis. I chose this product for its quality and safe ingredients. The dosage is suitable for daily use, and it's effective with a pleasant taste. Remember about 20 minutes of sunlight exposure.
Read More
9
Recovery support
Having suffered from COVID, I also deal with osteoporosis and hypothyroidism. This vitamin complex supports calcium absorption and boosts my immune system. I trust this brand entirely.
Read More
9
Significant improvement
After menopause, I developed osteoporosis and suffered a vertebral fracture. Within two weeks of taking two pills daily, my osteoporosis test showed significant improvement.
Read More
9
Maintains healthy bones
Excellent quality, though the box is larger than necessary for the two-month supply. This product is great for those deficient in vitamin D to maintain healthy bones and prevent osteoporosis due to limited sun exposure.
Read More
Frequently Asked Questions
7.5
Improved condition
210 people found this helpful
I have severe osteoporosis and previously experienced poor blood clotting. I noticed clear improvements shortly after starting this supplement; bleeding reduced significantly by the second day and nearly stopped within a week. Joint pain lessened, allowing me to take painkillers less often. The small capsules are easy to consume, and the combined vitamins support my health in the Ural climate. However, I paused during my COVID illness due to clotting risks. The packaging is oversized for the contents, leading to unnecessary plastic waste.
9
Significant improvement
After menopause, I developed osteoporosis and suffered a vertebral fracture. Within two weeks of taking two pills daily, my osteoporosis test showed significant improvement.
9
Visible changes
6 people found this helpful
My son has osteoporosis and blood clotting issues. Within days of taking this supplement, bleeding decreased significantly, and joint pain improved, reducing the need for painkillers. The small capsules are easy to take, and the price is very reasonable for such quick results.
7.5
Enhanced well-being
3 people found this helpful
Vitamin D is essential for calcium absorption and bone health. Deficiency can lead to osteoporosis. This supplement has helped improve my overall condition; I feel more energetic and my cycle has normalised.
7.5
Promotes bone health
The combination of vitamins D3 and K2 effectively promotes bone health and prevents osteoporosis. Vitamin D3 aids calcium and phosphorus assimilation, while K2 enhances D3’s effects. They also help reduce inflammation in the cardiovascular system.
7.5
Necessary nutrition
2 people found this helpful
The vegetarian ingredients in this supplement, especially the vitamin K, enhance vitamin D absorption, important for osteoporosis prevention. The dosage is suitable at once a day.
9
Effective supplement
2 people found this helpful
Suffering from osteoporosis and low vitamin D levels, this Life Extension supplement has proven excellent. My blood tests confirm the improvement.
7.5
Hormonal benefits
1 people found this helpful
As an endocrinologist, I recommend particularly high doses of vitamin D for optimal health. This product, which includes vitamin K, is effective and safe, benefitting bone health and preventing osteoporosis.
8
We explored the mechanisms by which vitamin D3 might regulate bone metabolism and help combat osteoporosis, particularly in light of vitamin D insufficiency. By utilizing various mouse models, including those genetically modified to express certain genes related to vitamin D, we assessed how these factors contributed to bone health.
Our findings revealed that a deficiency in active vitamin D, or 1,25-dihydroxyvitamin D, led to decreased levels of an important protein called Sirt1, which is crucial for bone health. This drop in Sirt1 resulted in accelerated bone loss. Encouragingly, we discovered that overexpressing Sirt1 in mesenchymal stem cells could actually reverse this bone loss. It achieved this by reducing oxidative stress and promoting healthy bone formation while minimizing bone resorption.
Additionally, our study showed that vitamin D3 boosts Sirt1 levels through a direct interaction with its gene promoter. This means that adequate vitamin D not only supports Sirt1 levels but also plays a key role in regulating its activity in bone cells. We also examined the effects of resveratrol, a compound that activates Sirt1, and found it could mitigate the negative impact of vitamin D insufficiency on bone health.
Overall, we observed that the vitamin D-Sirt1/PGC1α axis is vital for maintaining bone health, especially when vitamin D levels are insufficient. These insights highlight the potential for targeting this pathway as a promising strategy for preventing and treating osteoporosis.
Our findings revealed that a deficiency in active vitamin D, or 1,25-dihydroxyvitamin D, led to decreased levels of an important protein called Sirt1, which is crucial for bone health. This drop in Sirt1 resulted in accelerated bone loss. Encouragingly, we discovered that overexpressing Sirt1 in mesenchymal stem cells could actually reverse this bone loss. It achieved this by reducing oxidative stress and promoting healthy bone formation while minimizing bone resorption.
Additionally, our study showed that vitamin D3 boosts Sirt1 levels through a direct interaction with its gene promoter. This means that adequate vitamin D not only supports Sirt1 levels but also plays a key role in regulating its activity in bone cells. We also examined the effects of resveratrol, a compound that activates Sirt1, and found it could mitigate the negative impact of vitamin D insufficiency on bone health.
Overall, we observed that the vitamin D-Sirt1/PGC1α axis is vital for maintaining bone health, especially when vitamin D levels are insufficient. These insights highlight the potential for targeting this pathway as a promising strategy for preventing and treating osteoporosis.
8
Biosimilar denosumab matches reference drug
We conducted a thorough investigation into how vitamin D3 supplementation impacts the treatment of postmenopausal osteoporosis. The study utilized a solid methodology, featuring a randomized controlled design that involved two groups of postmenopausal women diagnosed with osteoporosis. One group received a biosimilar version of denosumab while the other received the reference product, Prolia. Additionally, both groups were supplemented with daily doses of 500 international units of vitamin D3 and 1000 mg of calcium to support overall bone health.
When we analyzed the results, we observed that while the supplementation of vitamin D3 was part of the treatment protocol, the primary focus remained on comparing the effectiveness and safety of the two forms of denosumab. The outcomes mainly centered on improvements in bone density at specific sites, such as the lumbar spine and femur neck. However, the benefits directly attributable to vitamin D3 supplementation were not distinctly isolated in this study's findings.
Overall, the findings revealed that the biosimilar denosumab was just as effective as the reference drug in managing osteoporosis, offering a potentially more affordable treatment option for patients. While vitamin D3 is essential for bone health, the significance of its individual role in this study is less clear, as the primary benefits were linked more to the denosumab treatments.
When we analyzed the results, we observed that while the supplementation of vitamin D3 was part of the treatment protocol, the primary focus remained on comparing the effectiveness and safety of the two forms of denosumab. The outcomes mainly centered on improvements in bone density at specific sites, such as the lumbar spine and femur neck. However, the benefits directly attributable to vitamin D3 supplementation were not distinctly isolated in this study's findings.
Overall, the findings revealed that the biosimilar denosumab was just as effective as the reference drug in managing osteoporosis, offering a potentially more affordable treatment option for patients. While vitamin D3 is essential for bone health, the significance of its individual role in this study is less clear, as the primary benefits were linked more to the denosumab treatments.
8
We explored the impact of vitamin D3 supplementation on osteoporosis in a unique case involving a 30-year-old female suffering from recurrent isolated sleep paralysis. This patient, who had a significant history of osteoporosis and low vitamin D3 levels, underwent a holistic management approach that included yoga, meditation, and chanting alongside vitamin D3 supplementation.
Initially, her bone density T-score was notably low at below -2.5, indicating a serious risk for osteoporosis. After carefully integrating vitamin D3 into her management plan, her bone density improved, showing a T-score of -2.1 two years later, along with a boost in her vitamin D3 levels. While our findings are promising, it's essential to note that the improvements observed may be attributed to the comprehensive nature of the treatment rather than the vitamin D3 alone.
This highlights the importance of considering a multi-faceted approach to health, combining lifestyle changes with nutritional support for those suffering from osteoporosis. Therefore, while vitamin D3 seems beneficial, we should be cautious about isolating its effects without further targeted research.
Initially, her bone density T-score was notably low at below -2.5, indicating a serious risk for osteoporosis. After carefully integrating vitamin D3 into her management plan, her bone density improved, showing a T-score of -2.1 two years later, along with a boost in her vitamin D3 levels. While our findings are promising, it's essential to note that the improvements observed may be attributed to the comprehensive nature of the treatment rather than the vitamin D3 alone.
This highlights the importance of considering a multi-faceted approach to health, combining lifestyle changes with nutritional support for those suffering from osteoporosis. Therefore, while vitamin D3 seems beneficial, we should be cautious about isolating its effects without further targeted research.
References
- Mendoza-Vargas LÁ, Sevilla-Fuentes S, Bautista-Becerril B, Berthaúd-González B, Falfán-Valencia R, et al. IgG4-RD-Associated Mikulicz Syndrome Without Classic Systemic Involvement-A Case Report. J Clin Med. 2025;14. 10.3390/jcm14030958
- Yang C, Chen L, Guo X, Sun H, Miao D. The Vitamin D-Sirt1/PGC1α Axis Regulates Bone Metabolism and Counteracts Osteoporosis. J Orthop Translat. 2025;50:211. 10.1016/j.jot.2024.10.011
- Paul T, Garg B, Kapoor N, Patil V, Kachnerkar N, et al. A Prospective, Active-controlled, Randomized, Double-blind, Multicenter, Phase III Study to Compare the Safety and Efficacy of Biosimilar Denosumab vs Reference Denosumab in the Treatment of Postmenopausal Osteoporosis. J Assoc Physicians India. 2025;73:e8. 10.59556/japi.73.0772
- Sawant D, Kamble N. Overcoming Recurrent Isolated Sleep Paralysis: A Case Report of Integrative Management With Yoga, Meditation, and Vitamin D3 Supplementation. Cureus. 2024;16:e76626. 10.7759/cureus.76626
- Kittaka A. Synthetic Studies on Vitamin D Derivatives with Diverse but Selective Biological Activities. Chem Pharm Bull (Tokyo). 2025;73:1. 10.1248/cpb.c24-00598
- Elmalah SG, Mohsen ROM, Hassan R. Selenium nano particles versus nano vitamin D3 in modulating anastrozole-induced osteoporosis on the mandibular alveolar bone of albino rats. J Stomatol Oral Maxillofac Surg. 2024. 10.1016/j.jormas.2024.102181
- Chang CH, Yang SJ, Young TH, Yao WC. Effect of co-loaded vitamin D3 on intravenous injectable raloxifene delivery system. Colloids Surf B Biointerfaces. 2025;246:114379. 10.1016/j.colsurfb.2024.114379
- Kluijver LG, Wagenmakers MAEM, Wilson JHP, Langendonk JG. The impact of minimal sunlight exposure on bone health: insights from a cohort study in erythropoietic protoporphyria. J Clin Endocrinol Metab. 2024. 10.1210/clinem/dgae729
- Chen Y, Qiu H, Xuan L, Jin Y, Chen R, et al. Acupuncture in Treating Osteopenia: A Multicenter, Randomized, Controlled Clinical Trial. Complement Med Res. 2024;31:516. 10.1159/000541440
- Moon RJ, D' Angelo S, Curtis EM, Ward KA, Crozier SR, et al. Pregnancy vitamin D supplementation and offspring bone mineral density in childhood follow-up of a randomized controlled trial. Am J Clin Nutr. 2024;120:1134. 10.1016/j.ajcnut.2024.09.014
- Pinto-Bonilla R, Baeza-Noci J, Blanco CC, Gumbau GJV, Fernández RJ, et al. Real-world effectiveness and safety of combined calcium 600 mg and cholecalciferol 2000 IU for treating vitamin d deficiency: Results from a nationwide study with focus in osteoporosis. Bone Rep. 2024;22:101796. 10.1016/j.bonr.2024.101796
- Xu D, Liu J, Zhang D, Zhang X, Huang C, et al. [Effects of thunder-fire moxibustion on balance function and musculoskeletal metabolism in female patients of primary osteoporosis with low muscle mass]. Zhongguo Zhen Jiu. 2024;44:859. 10.13703/j.0255-2930.20231229-0002
- Shin S, Hong N, Rhee Y. A randomized controlled trial of the effect of raloxifene plus cholecalciferol versus cholecalciferol alone on bone mineral density in postmenopausal women with osteopenia. JBMR Plus. 2024;8:ziae073. 10.1093/jbmrpl/ziae073
- Wu T, Lin Z, Wang C, Liu X. Correlation between vitamin D levels and blood pressure in elderly hypertensive patients with osteoporosis. Front Med (Lausanne). 2024;11:1396254. 10.3389/fmed.2024.1396254
