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Life Extension Magnesium Caps
SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.5
USERS' SCORE
Good
Based on 36 Reviews
8.7
Supplement Facts
Serving Size: 1 Vegetarian Capsule
Amount Per Serving
%DV
Magnesium [as magnesium oxide, citrate, succinate)
500 mg
119%

Top Medical Research Studies

9.5
Magnesium reduces postoperative back pain
Effect of perioperative intravenous magnesium sulfate on postoperative pain after iliac venous stenting.
Direct relevance to magnesium use
We explored the effectiveness of magnesium sulfate (MS) in relieving low back pain (LBP) for patients who underwent iliac venous stenting. This study involved 97 patients, divided into two groups: one received MS infusion during their surgery, while the other did not.

Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.

Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
Read More
9
Magnesium's role in back pain relief
Supplementation with alkaline minerals reduces symptoms in patients with chronic low back pain.
Moderately relevant findings observed
We investigated whether supplementation with alkaline minerals could ease chronic low back pain. In a study with 82 participants, those who took a lactose-based alkaline multimineral supplement for four weeks reported a significant 49% reduction in pain scores.

We also noted an increase in blood buffering capacity and pH, indicating an improved acid-base balance. Although intracellular magnesium levels increased, plasma magnesium slightly decreased, suggesting that while the supplementation helped alleviate pain, it didn't significantly impact magnesium levels overall.

This study highlights the potential benefits of correcting acid-base balance to reduce low back pain symptoms.
Read More
9
Magnesium therapy aids back pain
A double-blinded randomised controlled study of the value of sequential intravenous and oral magnesium therapy in patients with chronic low back pain with a neuropathic component.
Explores magnesium's combined benefits
We conducted a double-blind study to evaluate the effectiveness of magnesium therapy for chronic low back pain that has a neuropathic component. Our research involved 80 patients, all of whom were already engaged in physical therapy and taking medications like anticonvulsants and antidepressants.

Among the participants, we divided them into two groups: one group received a placebo for six weeks, while the other group was treated with a two-week intravenous magnesium infusion followed by four weeks of oral magnesium supplements.

The results were promising for those in the magnesium group. By the end of the study, their pain intensity decreased significantly, with scores dropping from an average of 7.5 to 4.7 over six months. Additionally, we observed notable improvements in their lumbar spine mobility, suggesting that magnesium therapy could be beneficial for those suffering from this type of chronic pain.

Overall, our findings indicate that sequential intravenous and oral magnesium treatment can effectively ease pain and enhance mobility in individuals with refractory low back pain featuring a neuropathic aspect.
Read More

Most Useful Reviews

9.5
Alleviated back pain
I started taking magnesium for my back pain. After a few days, I noticed a significant reduction in pain, and it almost disappeared when I continued taking it. However, the pain returns if I miss a dose!
Read More
9.5
Improved sleep quality
This is the best magnesium I have tried. I take one capsule an hour before bed, and it really relaxes my body, acting almost like a sleeping pill. For constipation, one capsule in the morning works wonders. The small size of the capsules is perfect, and they've significantly improved my sleep and relieved leg cramps and joint pain.
Read More
9.5
Eliminated leg pain
Excellent magnesium! I’ve bought it multiple times. Despite containing more magnesium oxide, it effectively alleviates deficiency symptoms such as numbness and pain in my calves. My anxiety has also diminished, and I highly recommend it.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 7 Researches
7.5
  • All Researches
9.5
Magnesium reduces postoperative back pain
Effect of perioperative intravenous magnesium sulfate on postoperative pain after iliac venous stenting.
Direct relevance to magnesium use
We explored the effectiveness of magnesium sulfate (MS) in relieving low back pain (LBP) for patients who underwent iliac venous stenting. This study involved 97 patients, divided into two groups: one received MS infusion during their surgery, while the other did not.

Patients who received MS experienced significantly lower pain levels at all follow-up intervals. We found that, at 24 hours after surgery, those in the magnesium group consumed much less tramadol—a common pain medication—compared to the control group. Additionally, the need for extra pain relief was lower among those who received magnesium.

Importantly, the side effects like nausea and vomiting were similar in both groups, indicating that magnesium can be a safe option for pain management after this type of surgery. Overall, the findings suggest that magnesium sulfate not only alleviates pain but also reduces reliance on opioids, making it a valuable treatment for postoperative care.
Read More
9
Magnesium therapy aids back pain
A double-blinded randomised controlled study of the value of sequential intravenous and oral magnesium therapy in patients with chronic low back pain with a neuropathic component.
Explores magnesium's combined benefits
We conducted a double-blind study to evaluate the effectiveness of magnesium therapy for chronic low back pain that has a neuropathic component. Our research involved 80 patients, all of whom were already engaged in physical therapy and taking medications like anticonvulsants and antidepressants.

Among the participants, we divided them into two groups: one group received a placebo for six weeks, while the other group was treated with a two-week intravenous magnesium infusion followed by four weeks of oral magnesium supplements.

The results were promising for those in the magnesium group. By the end of the study, their pain intensity decreased significantly, with scores dropping from an average of 7.5 to 4.7 over six months. Additionally, we observed notable improvements in their lumbar spine mobility, suggesting that magnesium therapy could be beneficial for those suffering from this type of chronic pain.

Overall, our findings indicate that sequential intravenous and oral magnesium treatment can effectively ease pain and enhance mobility in individuals with refractory low back pain featuring a neuropathic aspect.
Read More
9
Magnesium's role in back pain relief
Supplementation with alkaline minerals reduces symptoms in patients with chronic low back pain.
Moderately relevant findings observed
We investigated whether supplementation with alkaline minerals could ease chronic low back pain. In a study with 82 participants, those who took a lactose-based alkaline multimineral supplement for four weeks reported a significant 49% reduction in pain scores.

We also noted an increase in blood buffering capacity and pH, indicating an improved acid-base balance. Although intracellular magnesium levels increased, plasma magnesium slightly decreased, suggesting that while the supplementation helped alleviate pain, it didn't significantly impact magnesium levels overall.

This study highlights the potential benefits of correcting acid-base balance to reduce low back pain symptoms.
Read More
8
Magnesium shows promise for IVDD
ROS-responsive magnesium-containing microspheres for antioxidative treatment of intervertebral disc degeneration.
Moderate relevance to magnesium treatment
We explored the potential of magnesium-containing microspheres to help manage intervertebral disc degeneration (IVDD), a condition often linked with back pain. This innovative treatment focuses on using microspheres that respond to reactive oxygen species, which are indicators of oxidative stress often seen in IVDD. By targeting these harmful agents, we aimed to reduce the associated inflammation and pain.

The microspheres, composed of a polymer shell and a magnesium core, work by releasing hydrogen gas in response to oxidative conditions, which can help neutralize damaging free radicals in the body. We observed significant improvements in a rat model of disc degeneration, which included less damage to the disc structure, reduced cell death, and overall better disc health.

The results of this study highlight magnesium's role as a key component in enhancing the antioxidative capacity of the treatment. This not only mitigates the effects of IVDD but also supports the idea that antioxidant therapies may hold promise for alleviating back pain. Importantly, we noted that this approach showed strong biocompatibility and minimal toxicity, making it a potential option for future clinical applications.
Read More
8
Magnesium and back pain relief
Green exercise and mg-ca-SO thermal balneotherapy for the treatment of non-specific chronic low back pain: a randomized controlled clinical trial.
Moderate effectiveness observed
We conducted a study to explore how magnesium treatment and mountain hiking might alleviate non-specific chronic low back pain (nscLBP). In this randomized controlled trial, we divided eighty participants into three groups: one engaged in green exercise (mountain hiking), another combined hiking with magnesium-calcium-sulfate thermal baths, and a control group received no treatment.

Our findings showed significant improvements in back pain among participants who participated in hiking and bathing in thermal water compared to those who didn't receive any intervention. However, it is important to note that we cannot isolate the benefits of magnesium treatment since it was combined with the physical activity of hiking. Therefore, while magnesium's involvement is notable, its individual impact remains unclear from our results.

This study highlights the promise of integrating physical activities like mountain hiking alongside therapeutic treatments for managing chronic back pain. Future research should delve deeper into the long-term effects of such multi-faceted therapies to fully understand the role of magnesium in this context.
Read More

User Reviews

USERS' SCORE
Good
Based on 36 Reviews
8.7
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9.5
Alleviated back pain
I started taking magnesium for my back pain. After a few days, I noticed a significant reduction in pain, and it almost disappeared when I continued taking it. However, the pain returns if I miss a dose!
9.5
Improved sleep quality
This is the best magnesium I have tried. I take one capsule an hour before bed, and it really relaxes my body, acting almost like a sleeping pill. For constipation, one capsule in the morning works wonders. The small size of the capsules is perfect, and they've significantly improved my sleep and relieved leg cramps and joint pain.
Read More
9.5
Eliminated leg pain
Excellent magnesium! I’ve bought it multiple times. Despite containing more magnesium oxide, it effectively alleviates deficiency symptoms such as numbness and pain in my calves. My anxiety has also diminished, and I highly recommend it.
9.5
Eased heart pain
After the first use, my heart, lower back, and bone pains disappeared, along with my constipation. These results are striking given my history of pain. I decided to try this product after watching recommendations regarding magnesium following my COVID vaccine.
9.5
Numbness vanished
Excellent magnesium! My calf pains have disappeared, and my digestion has improved significantly.
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