We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Read More
4
Magnesium shows limited sleep benefits
Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis.
We explored the effects of magnesium supplementation on insomnia in older adults through a systematic review and meta-analysis. Our investigation included several studies that compared magnesium with a placebo or no treatment.
We found three randomized control trials involving 151 older adults across three countries. The pooled results indicated that individuals taking magnesium had a notable decrease in sleep onset latency, averaging a reduction of 17.36 minutes compared to those on placebo. However, the improvement in total sleep time, which increased by 16.06 minutes in the magnesium group, did not reach statistical significance.
Despite these findings, we must emphasize that the overall quality of the research is below standards necessary for making firm recommendations. All studies reviewed showed a moderate to high risk of bias, and the evidence quality ranged from low to very low. Nonetheless, magnesium is an affordable and widely accessible option for those struggling with insomnia symptoms, suggesting it may be a reasonable consideration for some older adults.
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8
Magnesium may reduce daytime sleepiness
Magnesium Intake and Sleep Disorder Symptoms: Findings from the Jiangsu Nutrition Study of Chinese Adults at Five-Year Follow-Up.
We set out to explore how dietary magnesium might impact symptoms of insomnia, such as falling asleep during the day and snoring at night. Our study included a significant sample of 1,487 adults from the Jiangsu Nutrition Study, which allowed us to gather valuable information about their magnesium intake and sleep experiences. Over five years, we assessed participants' magnesium consumption through detailed food records and later examined their sleep patterns via a questionnaire.
Our findings revealed that the average magnesium intake among participants was 332.5 mg per day. Interestingly, we found that around 5.3% reported falling asleep during the day, 13.2% faced daytime sleepiness, and 35.7% experienced snoring at night. Rising through the quartiles of magnesium intake, we observed a promising decrease in the chance of women experiencing daytime falling asleep; however, this effect wasn’t mirrored in men. It’s crucial to note that we didn’t find significant associations between magnesium intake and daytime sleepiness or night snoring for either gender.
Overall, it seems that dietary magnesium might offer long-term benefits in reducing daytime sleepiness in women, while more research could clarify its effects on other symptoms. This makes magnesium an interesting dietary consideration for those seeking to improve their sleep quality.
Read More
Most Useful Reviews
9
Fights insomnia effectively
312 people found this helpful
Using Magnesium Caps has markedly improved my daily sleepiness, irritability, and headaches. I found that it reduces insomnia, and I no longer experience migraines or apathy. I feel refreshed after a good night’s sleep. I highly recommend it, especially if taken before bedtime!
Read More
9
Relieves insomnia swiftly
29 people found this helpful
This product is fantastic! I chose it for its effective magnesium blend to tackle stress and insomnia. It can be taken at any time without side effects, and I feel relaxed within 30 minutes of taking it. I wake up refreshed. I’ve recommended it to friends as well.
Read More
9
Improves sleep significantly
18 people found this helpful
After starting this magnesium, I've been sleeping much better, and my irritability has vanished. I highly recommend magnesium for anyone struggling with insomnia or restless sleep.
We explored the potential benefits of a supplement containing magnesium, melatonin, and vitamin B complex in treating insomnia. The study involved 60 patients diagnosed with insomnia, who were divided into a study group and a control group. Over three months, the study group received a daily dose of the supplement, while the control group did not receive it.
At the start, both groups had similar levels of insomnia, indicated by their scores on the Athens insomnia scale. However, after three months of supplementation, the study group showed a significant improvement, with their insomnia scores decreasing, indicating mild insomnia. In contrast, the control group’s scores remained stable, suggesting they continued to experience moderate insomnia.
Although magnesium was part of the supplement, the study design makes it challenging to isolate its specific effects on insomnia. Nevertheless, we observed that combining magnesium with melatonin and vitamin B complex potentially enhances sleep quality for those struggling with insomnia.
Read More
9
Magnesium improves elderly insomnia
The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
Read More
9
Magnesium may aid sleep quality
The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial.
We conducted a double-blind, placebo-controlled clinical trial in a long-term care facility in Italy to explore whether nightly doses of melatonin, magnesium, and zinc could benefit residents suffering from primary insomnia. Our study involved 43 participants, who were either given a combined supplement of these nutrients or a placebo for eight weeks.
The primary objective was to measure sleep quality using the Pittsburgh Sleep Quality Index, while we also considered secondary indicators like daytime sleepiness and overall quality of life. The results revealed that the combined approach of melatonin, magnesium, and zinc appeared to improve both sleep and quality of life for residents struggling with insomnia.
However, since magnesium was tested alongside two other supplements, we cannot clearly attribute the benefits directly to magnesium alone. Overall, the findings suggest a positive effect on sleep quality and well-being for long-term care residents dealing with insomnia, but we must be cautious in isolating each nutrient's individual effectiveness.
Read More
8
Magnesium improves insomnia in diabetes
Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
We conducted a randomized controlled trial focusing on individuals with diabetes who struggle with insomnia. Over two months, we examined the effects of magnesium and potassium supplementation on sleep quality and hormone levels. Our study included 320 patients, and after follow-up, 290 patients completed the trial. We assessed insomnia severity using the Insomnia Severity Index and analyzed changes in melatonin and cortisol levels, which are key sleep hormones.
Our findings indicated that magnesium supplementation—whether alone or in combination with potassium—had a notable positive impact. Participants who received magnesium and potassium demonstrated significant improvements in both insomnia severity and sleep hormone levels. It was exciting to see how these supplements could enhance sleep duration and quality in those facing the dual challenges of insomnia and diabetes.
Although the combination of magnesium and potassium was effective, we recognize that this limits a clear assessment of magnesium's isolated effects. Nevertheless, our research adds valuable insights on how these minerals may play a role in managing insomnia among diabetic patients.
Read More
8
Magnesium may aid post-surgery insomnia
Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial.
We conducted a study to explore how magnesium affects insomnia in patients undergoing lumbar fixation surgery. Our research involved 80 participants, divided into two groups: one received conventional general anesthesia supplemented with magnesium sulfate, while the other had standard anesthesia without magnesium.
We assessed various factors, including insomnia severity using the Insomnia Severity Index and post-operative delirium through the Memorial Delirium Assessment Scale. Interestingly, our findings indicated a significant relationship between the administration of magnesium and reduced instances of post-operative insomnia.
This suggests that magnesium may be beneficial in easing sleep disturbances experienced by some patients after surgery. However, we also noted variations due to other factors like pain and depression, which could influence the overall results.
While the relationship is promising, it’s essential to recognize that there may be multiple factors at play that contribute to insomnia post-surgery. Overall, our evaluation presents magnesium as a potentially helpful option for enhancing sleep quality in these patients.
Using Magnesium Caps has markedly improved my daily sleepiness, irritability, and headaches. I found that it reduces insomnia, and I no longer experience migraines or apathy. I feel refreshed after a good night’s sleep. I highly recommend it, especially if taken before bedtime!
Read More
9
Relieves insomnia swiftly
29 people found this helpful
This product is fantastic! I chose it for its effective magnesium blend to tackle stress and insomnia. It can be taken at any time without side effects, and I feel relaxed within 30 minutes of taking it. I wake up refreshed. I’ve recommended it to friends as well.
Read More
9
Improves sleep significantly
18 people found this helpful
After starting this magnesium, I've been sleeping much better, and my irritability has vanished. I highly recommend magnesium for anyone struggling with insomnia or restless sleep.
Read More
9
Controls insomnia effectively
8 people found this helpful
Magnesium has significantly helped with my insomnia and high blood pressure. I manage to maintain normal blood pressure without medication. It acts as a natural tranquiliser and is essential for my overall health, especially when taken before bed.
Read More
9
Quick insomnia remedy
8 people found this helpful
Best magnesium supplement for me! I have suffered from knee, foot, and back pain along with extreme insomnia. Nothing else worked as quickly or effectively. I take one capsule each night with dinner, as advised by my endocrinologist for optimal absorption. An hour later, I’m ready to sleep. It also alleviates my nerve pain and is reasonably priced, compared to others that can be more expensive. I’ll keep buying this brand. Plus, I've noticed I no longer need deodorant throughout the day, which is a bonus. I’d recommend this to teenagers too, ensuring they get enough magnesium in their diets.
Insomnia is a common sleep disorder characterized by the inability to fall asleep, stay asleep, or wake up too early and not be able to go back to sleep. Individuals experiencing insomnia may find that it affects their daytime functioning, leading to issues such as fatigue, mood disturbances, and difficulty concentrating. Insomnia can be classified into two main types: acute insomnia, which lasts for a short period often triggered by stress or life changes, and chronic insomnia, which occurs at least three times a week for three months or longer, and may require more in-depth evaluation and treatment.
Numerous factors can contribute to insomnia, including stress, anxiety, poor sleep habits, medical conditions, and the use of certain medications. Treatment for insomnia typically involves a combination of lifestyle changes, cognitive behavioral therapy for insomnia (CBT-I), and sometimes medication. Establishing a consistent sleep routine, creating a comfortable sleep environment, and practicing relaxation techniques can help improve sleep quality. If insomnia persists, it is advisable to consult a healthcare professional for proper diagnosis and customized treatment options.
Magnesium is a chemical element with the symbol Mg and atomic number 12. It is a lightweight, silvery-white metal that is a member of the alkaline earth metals group. Often classified as one of the most abundant elements in the Earth's crust, magnesium plays a crucial role in various biological functions and is essential for living organisms. In nature, magnesium can be found in large quantities, primarily in minerals such as dolomite and magnesite, and it is also present in seawater.
In terms of health benefits, magnesium is vital for numerous metabolic processes, including energy production, DNA synthesis, and muscle function. It contributes to bone health, helps regulate blood pressure, and supports bone formation by promoting the effects of vitamin D. The recommended dietary allowance (RDA) for magnesium varies by age and gender, but it is generally important to include magnesium-rich foods like leafy greens, nuts, seeds, and whole grains in your diet to ensure adequate intake. For those who may not receive enough magnesium through their diet alone, supplements are also available; however, it is advisable to consult a healthcare professional before starting any supplementation.
Magnesium is often touted as a natural remedy for improving sleep quality and managing insomnia. This essential mineral plays a crucial role in various bodily functions, including the regulation of neurotransmitters that send signals throughout the nervous system and brain. Some studies suggest that magnesium may assist in promoting relaxation by helping to regulate melatonin, a hormone responsible for sleep-wake cycles. Additionally, it may help reduce anxiety and stress, which are common culprits of sleep disturbances.
While many people report improved sleep after incorporating magnesium supplements or magnesium-rich foods—like leafy greens, nuts, and whole grains—into their diets, the scientific evidence is mixed. More research is needed to definitively establish its effectiveness in treating insomnia. If you're considering magnesium supplements, it's always best to consult with a healthcare professional to determine the appropriate dosage and ensure that it won’t interact with any medications you may be taking. Overall, while magnesium may offer some benefits for sleep, it is most effective when used as part of a comprehensive approach to improving sleep hygiene.
Based on user reviews, many individuals report experiencing improvements in their sleep quality and alleviation of insomnia symptoms within a relatively short time frame after starting magnesium supplementation. Several users indicate that they noticed positive changes within as little as three days Read Review or five days Read Review, often mentioning that their ability to fall asleep and overall sleep quality significantly improved during this period. Other reviewers noted improvements after about two weeks Read Review, suggesting that while some may see quick results, others might need a bit more time for the magnesium to take effect effectively.
Regular feedback from users commonly emphasizes the cumulative benefits of magnesium, as it also helps manage stress and mood fluctuations, further enhancing overall sleep quality Read Review. Ultimately, it seems that most users agree that incorporating magnesium into their nightly routine helps them achieve deeper, more restorative sleep quickly.
There is notable scientific research supporting the use of magnesium supplements for insomnia. A systematic review encompassing 15 studies revealed a trend towards improved sleep quality with magnesium supplementation, with five out of eight studies reporting better outcomes in sleep quality metrics like the Pittsburgh Sleep Quality Index (PSQI) [3]. Furthermore, a randomized controlled trial specifically targeting older adults found that daily magnesium supplementation led to significant improvements in sleep quality and overall insomnia severity over eight weeks [8]. This suggests that magnesium could be particularly beneficial for older adults who often suffer from insomnia.
Moreover, magnesium’s potential role extends to various groups facing different insomnia challenges, from diabetic patients [1] to those recovering from surgery [2]. Although studies show promise, it is crucial to note that results vary, and some studies reported mixed outcomes [3]. Thus, while magnesium may be a viable option for aiding those with sleep disturbances, further targeted research is necessary to refine our understanding of its effectiveness and optimal usage in treating insomnia.
Based on user reviews, a wide range of symptoms have shown improvement with magnesium supplementation. Many users report a significant reduction in insomnia, experiencing deeper and more restorative sleep. For instance, one user noted that their sleep quality improved markedly, with some witnessing reduced time to fall asleep Read Review. Several users also highlight enhanced mood and reduced irritability; one reviewer mentioned that their irritability had vanished, attributing this change to the magnesium Read Review.
Additionally, people have shared experiences of alleviated headaches and muscle pain, further emphasizing the multifaceted benefits of magnesium. A user remarked on the relief from migraines and occurrences of muscle cramps after incorporating magnesium into their routine Read Review. While results can vary widely from person to person, the common thread in these reviews suggests that magnesium can be an effective tool for battling sleep issues and improving overall health.
Users report positive experiences when combining magnesium supplements with other products to tackle insomnia. For instance, one user highlighted the effectiveness of using magnesium alongside vitamin D, noting that this combination significantly alleviated symptoms of insomnia and headaches Read Review. Additionally, some users noted enhanced sleep quality when taking magnesium with other supplements or medications. One reviewer mentioned that taking magnesium in conjunction with a sleeping pill led to less tossing and turning, resulting in a more restful night Read Review.
Moreover, several users expressed that magnesium itself serves as a natural tranquilizer, effectively calming the mind and body in preparation for sleep, which they have found beneficial when managing their overall health alongside other supplements Read Review. This suggests that magnesium can be a versatile component in a broader strategy for combating insomnia, whether used alone or in concert with other aids.
Research indicates that magnesium supplementation may help alleviate insomnia symptoms, but specific optimal dosages can vary across different studies and populations. For example, in a trial involving elderly individuals, a daily dose of 500 mg of magnesium was associated with significant improvements in sleep efficiency and overall insomnia severity over an 8-week period [8]. Additionally, studies focusing on general sleep quality improvements suggest that magnesium can contribute positively at daily doses ranging from around 300 mg to 500 mg, particularly for those starting with lower magnesium levels [3].
However, it's essential to note that not all studies agree on a uniform optimal dose, and some variations in sleep outcomes were noted based on the magnesium formulation and context of use, such as post-surgical recovery or specific health conditions [2][7]. Thus, while the emerging consensus leans towards magnesium being beneficial in mitigating insomnia, individuals should consult healthcare professionals to determine the most effective dosage tailored to their specific needs.
9
No more insomnia
I began sleeping well because of insomnia and constipation issues. By the third day, my sleep improved and constipation vanished. I had concerns about side effects due to high potency, but I had none. Good product!
9
Cramps gone
1 people found this helpful
Excellent! I can only describe this product as wonderful! My cramps and insomnia have vanished. The results were noticeable within just five days.
9
Headache and cramp relief
5 people found this helpful
This magnesium is the best I've tried. After two weeks, I noticed a significant reduction in insomnia, leg cramps, and headaches. Magnesium is essential for everyone, aiding in various bodily functions.
10
Stable emotions
1 people found this helpful
Magnesium is crucial for stabilising my emotions. Over the past two months, I have experienced notable improvements in my insomnia and mood. I can now sleep well, which is a blessing.
10
Improves sleep
1 people found this helpful
I bought magnesium to help with insomnia based on a friend's recommendation. It significantly reduced the time it takes me to fall asleep, and it has also alleviated my restless legs.
9
Improves sleep significantly
18 people found this helpful
After starting this magnesium, I've been sleeping much better, and my irritability has vanished. I highly recommend magnesium for anyone struggling with insomnia or restless sleep.
9
Vitamin D importance
2 people found this helpful
Magnesium is crucial for combating symptoms like headaches and insomnia, which I've suffered from. I recommend using both magnesium and vitamin D regularly, as they greatly alleviate these issues. Their deficiency can lead to significant problems, so ensure you monitor your intake.
7.5
Less tossing
1 people found this helpful
I suffer from severe insomnia and muscle pain that disrupts my sleep. When I take magnesium with a sleeping pill, I toss and turn less and feel much better.
9
Controls insomnia effectively
8 people found this helpful
Magnesium has significantly helped with my insomnia and high blood pressure. I manage to maintain normal blood pressure without medication. It acts as a natural tranquiliser and is essential for my overall health, especially when taken before bed.
7
Magnesium may improve insomnia
Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review.
We examined the potential benefits of magnesium supplements for improving sleep quality through a detailed analysis of existing clinical studies. Our systematic review focused specifically on trials investigating how magnesium affects insomnia, which have gained popularity among people seeking natural remedies for sleep problems.
A total of 15 relevant studies were reviewed. Among these, eight studies looked specifically at sleep-related outcomes, often employing the Pittsburgh Sleep Quality Index (PSQI) to measure improvements. The results were promising—five out of the eight studies indicated that magnesium supplementation led to better sleep quality.
However, it's important to note that not all studies observed benefits; two showed no significant improvements, and one provided mixed results. Many of these studies varied in the dosage, type of magnesium used, and overall participant numbers, which made it challenging to draw firm conclusions. Still, the general trend suggests that magnesium could indeed be helpful, especially for those who start with low magnesium levels.
Ultimately, while the findings lean towards positive, further large-scale, randomized trials are necessary to confirm the effectiveness of specific magnesium formulations and dosages in treating insomnia. We take these outcomes seriously, considering them a first step towards understanding how this mineral can help those struggling with sleep issues.
9
Magnesium improves elderly insomnia
The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial.
We conducted a double-blind, placebo-controlled clinical trial to investigate the effects of magnesium supplementation on insomnia in elderly individuals. Our study involved 46 participants who were assigned either to receive 500 mg of magnesium daily or a placebo for a duration of 8 weeks.
Throughout the study, we employed various questionnaires, including the Insomnia Severity Index (ISI), to evaluate the participants' sleep quality both before and after the treatment period. We also monitored the intake of other nutrients and performed blood tests to assess hormone levels related to sleep.
The results showed that magnesium supplementation led to significant improvements in areas such as sleep efficiency, sleep onset timing, and overall insomnia severity. We observed increases in serum levels of melatonin and changes in cortisol and renin levels, indicating a physiological response that could enhance sleep quality.
Overall, it seems that supplementing with magnesium has the potential to improve sleep for older adults struggling with insomnia. This finding could pave the way for new, accessible treatment options for those affected by sleep disorders.
8
Magnesium improves insomnia in diabetes
Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus.
We conducted a randomized controlled trial focusing on individuals with diabetes who struggle with insomnia. Over two months, we examined the effects of magnesium and potassium supplementation on sleep quality and hormone levels. Our study included 320 patients, and after follow-up, 290 patients completed the trial. We assessed insomnia severity using the Insomnia Severity Index and analyzed changes in melatonin and cortisol levels, which are key sleep hormones.
Our findings indicated that magnesium supplementation—whether alone or in combination with potassium—had a notable positive impact. Participants who received magnesium and potassium demonstrated significant improvements in both insomnia severity and sleep hormone levels. It was exciting to see how these supplements could enhance sleep duration and quality in those facing the dual challenges of insomnia and diabetes.
Although the combination of magnesium and potassium was effective, we recognize that this limits a clear assessment of magnesium's isolated effects. Nevertheless, our research adds valuable insights on how these minerals may play a role in managing insomnia among diabetic patients.
8
Magnesium may aid post-surgery insomnia
Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial.
We conducted a study to explore how magnesium affects insomnia in patients undergoing lumbar fixation surgery. Our research involved 80 participants, divided into two groups: one received conventional general anesthesia supplemented with magnesium sulfate, while the other had standard anesthesia without magnesium.
We assessed various factors, including insomnia severity using the Insomnia Severity Index and post-operative delirium through the Memorial Delirium Assessment Scale. Interestingly, our findings indicated a significant relationship between the administration of magnesium and reduced instances of post-operative insomnia.
This suggests that magnesium may be beneficial in easing sleep disturbances experienced by some patients after surgery. However, we also noted variations due to other factors like pain and depression, which could influence the overall results.
While the relationship is promising, it’s essential to recognize that there may be multiple factors at play that contribute to insomnia post-surgery. Overall, our evaluation presents magnesium as a potentially helpful option for enhancing sleep quality in these patients.
4
Magnesium's unclear impact on insomnia
Exploring the Effect of Lactium™ and Zizyphus Complex on Sleep Quality: A Double-Blind, Randomized Placebo-Controlled Trial.
In a recent double-blind, placebo-controlled trial, we explored how LZComplex3, which contains magnesium among other ingredients, impacts sleep quality in healthy adults with mild insomnia. The study involved 171 participants after an initial week of placebo treatments to set a baseline for comparison. Over two weeks, these individuals were randomly assigned to receive either LZComplex3 or a placebo and their sleep quality was measured using the Pittsburgh Sleep Quality Index (PSQI).
While both groups reported improvements in their sleep quality scores, there were no significant differences between those taking LZComplex3 and those receiving the placebo. This indicates that although magnesium is a component of the treatment, its isolated impact on insomnia could not be clearly established. We also noted that participants experienced similar improvements in various secondary outcomes like mood, anxiety, and fatigue, whether they received the actual treatment or the placebo.
It's worth mentioning that some participants in the LZComplex3 group reported side effects, and a couple of these led to discontinuation of the treatment. Overall, without notable differences in sleep outcomes between the two groups, we conclude that magnesium's role in improving sleep quality through LZComplex3 remains uncertain, overshadowed possibly by a strong placebo response.
References
Khalid S, Bashir S, Mehboob R, Anwar T, Ali M, et al. Effects of magnesium and potassium supplementation on insomnia and sleep hormones in patients with diabetes mellitus. Front Endocrinol (Lausanne). 2024;15:1370733. 10.3389/fendo.2024.1370733
Fathy W, Hussein M, Elanwar R, Elmoutaz H, Abdelsadek DA, et al. Effect of intra-operative Magnesium sulphate on the occurrence of post-operative delirium and insomnia in patients undergoing lumbar fixation: a randomized controlled trial. BMC Anesthesiol. 2024;24:289. 10.1186/s12871-024-02579-6
Rawji A, Peltier MR, Mourtzanakis K, Awan S, Rana J, et al. Examining the Effects of Supplemental Magnesium on Self-Reported Anxiety and Sleep Quality: A Systematic Review. Cureus. 2024;16:e59317. 10.7759/cureus.59317
Mah J, Pitre T. Oral magnesium supplementation for insomnia in older adults: a Systematic Review & Meta-Analysis. BMC Complement Med Ther. 2021;21:125. 10.1186/s12906-021-03297-z
Djokic G, Vojvodić P, Korcok D, Agic A, Rankovic A, et al. The Effects of Magnesium - Melatonin - Vit B Complex Supplementation in Treatment of Insomnia. Open Access Maced J Med Sci. 2019;7:3101. 10.3889/oamjms.2019.771
Cao Y, Zhen S, Taylor AW, Appleton S, Atlantis E, et al. Magnesium Intake and Sleep Disorder Symptoms: Findings from the Jiangsu Nutrition Study of Chinese Adults at Five-Year Follow-Up. Nutrients. 2018;10. 10.3390/nu10101354
Scholey A, Benson S, Gibbs A, Perry N, Sarris J, et al. Exploring the Effect of Lactium™ and Zizyphus Complex on Sleep Quality: A Double-Blind, Randomized Placebo-Controlled Trial. Nutrients. 2017;9. 10.3390/nu9020154
Abbasi B, Kimiagar M, Sadeghniiat K, Shirazi MM, Hedayati M, et al. The effect of magnesium supplementation on primary insomnia in elderly: A double-blind placebo-controlled clinical trial. J Res Med Sci. 2012;17:1161.
Rondanelli M, Opizzi A, Monteferrario F, Antoniello N, Manni R, et al. The effect of melatonin, magnesium, and zinc on primary insomnia in long-term care facility residents in Italy: a double-blind, placebo-controlled clinical trial. J Am Geriatr Soc. 2011;59:82. 10.1111/j.1532-5415.2010.03232.x
Mucci M, Carraro C, Mancino P, Monti M, Papadia LS, et al. Soy isoflavones, lactobacilli, Magnolia bark extract, vitamin D3 and calcium. Controlled clinical study in menopause. Minerva Ginecol. 2006;58:323.
Hornyak M, Haas P, Veit J, Gann H, Riemann D. Magnesium treatment of primary alcohol-dependent patients during subacute withdrawal: an open pilot study with polysomnography. Alcohol Clin Exp Res. 2004;28:1702.
Hornyak M, Voderholzer U, Hohagen F, Berger M, Riemann D. Magnesium therapy for periodic leg movements-related insomnia and restless legs syndrome: an open pilot study. Sleep. 1998;21:501.