Overview
SCIENTIFIC SCORE
Moderately Effective
Based on 19 Researches
8.2
USERS' SCORE
Good
Based on 32 Reviews
8
Supplement Facts
Serving Size: 1 Vegetarian Capsule
Amount Per Serving
%DV
Magnesium [as magnesium oxide, citrate, succinate)
500 mg
119%
Top Medical Research Studies
9
We explored the effects of a special material called magnesium-based zeolitic imidazolate frameworks, or Mg-ZIF, on osteoporosis. This study aimed to find a way to tackle osteoporosis by reducing reactive oxygen species (ROS)—harmful molecules that affect our bone health.
Our findings revealed that Mg-ZIF is effective at scavenging ROS, which helps boost the bone-forming ability of bone mesenchymal stem cells (BMSCs). By promoting osteogenic differentiation, Mg-ZIF supports the formation of new bone while simultaneously discouraging the development of fat cells from BMSCs, a process known as lipogenic differentiation.
In our in vivo experiments, we confirmed that administering Mg-ZIF could successfully lower ROS levels and mitigate the effects of osteoporosis. On a deeper level, the mechanism behind this involves Mg-ZIF enhancing BMSC differentiation into bone-forming cells by upregulating specific lipid metabolic pathways.
Overall, we believe that Mg-ZIF holds promise as a therapeutic approach for osteoporosis. By addressing the oxidative stress in the bone marrow environment, it opens a new door for potential treatments targeting this common bone disease.
Our findings revealed that Mg-ZIF is effective at scavenging ROS, which helps boost the bone-forming ability of bone mesenchymal stem cells (BMSCs). By promoting osteogenic differentiation, Mg-ZIF supports the formation of new bone while simultaneously discouraging the development of fat cells from BMSCs, a process known as lipogenic differentiation.
In our in vivo experiments, we confirmed that administering Mg-ZIF could successfully lower ROS levels and mitigate the effects of osteoporosis. On a deeper level, the mechanism behind this involves Mg-ZIF enhancing BMSC differentiation into bone-forming cells by upregulating specific lipid metabolic pathways.
Overall, we believe that Mg-ZIF holds promise as a therapeutic approach for osteoporosis. By addressing the oxidative stress in the bone marrow environment, it opens a new door for potential treatments targeting this common bone disease.
Read More
9
In our exploration of osteoporosis treatment, we focused on the effects of magnesium, particularly when combined with phosphorylated collagen peptide-magnesium chelates. Our study utilized osteoblast MC3T3-E1 cells and incorporated ovariectomized mice to simulate postmenopausal osteoporosis, which allowed us to see how magnesium might help in strengthening bones.
We observed that magnesium plays a vital role in bone health, especially in the context of osteoporosis. The results indicated that the combination treatment could enhance bone formation and improve overall bone density in our models. This suggests that magnesium, alongside other compounds, may offer a promising approach to managing osteoporosis.
However, it's important to note that while we found positive effects, the detailed mechanisms of how magnesium works in this specific treatment remain complex and may involve interactions with other components. Further research is needed to fully understand its efficacy and the best ways to integrate magnesium into osteoporosis treatment strategies.
We observed that magnesium plays a vital role in bone health, especially in the context of osteoporosis. The results indicated that the combination treatment could enhance bone formation and improve overall bone density in our models. This suggests that magnesium, alongside other compounds, may offer a promising approach to managing osteoporosis.
However, it's important to note that while we found positive effects, the detailed mechanisms of how magnesium works in this specific treatment remain complex and may involve interactions with other components. Further research is needed to fully understand its efficacy and the best ways to integrate magnesium into osteoporosis treatment strategies.
Read More
9
Nanopowder eggshells improve bone health
We examined how nanopowder eggshells (NPES) could influence bone health in both healthy and ovariectomy-induced osteoporosis rats.
In our research, we found that NPES treatment significantly enhanced indicators of bone formation, like calcium and osteocalcin, particularly in healthy rats.
Additionally, in the ovariectomized group, NPES treatment helped improve levels of vital nutrients and reduced bone resorption.
Overall, our findings suggest that NPES may play a beneficial role in bettering bone health in osteoporosis models.
In our research, we found that NPES treatment significantly enhanced indicators of bone formation, like calcium and osteocalcin, particularly in healthy rats.
Additionally, in the ovariectomized group, NPES treatment helped improve levels of vital nutrients and reduced bone resorption.
Overall, our findings suggest that NPES may play a beneficial role in bettering bone health in osteoporosis models.
Read More
Most Useful Reviews
9
Muscle tension relief
I trust the quality of this magnesium product, which contains 500mg. It’s easy to consume, and the packaging is convenient. I find it effective in relieving muscle and nerve tension while also aiding in osteoporosis treatment.
Read More
9
Prevents muscle tension
An excellent supplement that should not be overlooked for preventing osteoporosis and muscle tension. It is advisable to take it at night. The product’s quality is outstanding, with sufficient magnesium per pill. It has no taste and is beneficial for bones and immunity, making it easy to consume.
Read More
9
Prevents Osteoporosis
By ensuring the correct mineralisation of bones, magnesium prevents the development of osteoporosis. It also helps regulate blood pressure and consequently reduces the risk of cardiovascular diseases. Additionally, it significantly strengthens the nervous system.
Read More
Medical Researches
SCIENTIFIC SCORE
Moderately Effective
Based on 19 Researches
8.2
- All Researches
9
We examined how dietary intake of magnesium, along with potassium and sodium, influences bone health, specifically focusing on osteoporosis and bone mineral density (BMD) in adults across the U.S. Our analysis was based on data from the National Health and Nutrition Examination Surveys, which spanned from 2005 to 2018, involving over 10,000 participants.
The findings revealed a positive association between higher dietary intake of potassium, magnesium, and sodium and improved BMD of the femur. This means that those who consumed more of these nutrients tended to have stronger bones. Additionally, we observed that a higher intake of these minerals was linked to a lower occurrence of osteopenia and osteoporosis.
Our study highlights how magnesium, when part of a broader nutrient intake that includes potassium and sodium, could play a significant role in maintaining bone health. While our research points to a beneficial relationship, more targeted studies are needed to definitively isolate the effects of magnesium alone on osteoporosis. Overall, this reinforces the importance of a balanced diet for bone health.
The findings revealed a positive association between higher dietary intake of potassium, magnesium, and sodium and improved BMD of the femur. This means that those who consumed more of these nutrients tended to have stronger bones. Additionally, we observed that a higher intake of these minerals was linked to a lower occurrence of osteopenia and osteoporosis.
Our study highlights how magnesium, when part of a broader nutrient intake that includes potassium and sodium, could play a significant role in maintaining bone health. While our research points to a beneficial relationship, more targeted studies are needed to definitively isolate the effects of magnesium alone on osteoporosis. Overall, this reinforces the importance of a balanced diet for bone health.
Read More
9
We delved into the use of a unique injectable hydrogel loaded with magnesium to address the challenges of repairing osteoporotic bone defects. The study aimed to understand how this magnesium-infused hydrogel could combat the excessive reactive oxygen species (ROS) that hinder bone repair. With impressive qualities such as excellent injectability and adaptability, the hydrogel can be introduced into irregular bone areas without the need for major surgery.
Once injected, the hydrogel not only transforms into a supportive scaffold but also begins to release hydrogen and magnesium ions. This release is key in reducing harmful intracellular ROS and guiding the immune response favorably by promoting macrophage polarization. We observed that this gel suppressed the formation of osteoclasts, the cells responsible for bone resorption, while simultaneously encouraging the growth of new bone cells.
Animal experiments further illuminated the effectiveness of the magnesium-loaded hydrogel, showing a remarkable ability to enhance the repair of bone defects by controlling inflammation and supporting bone formation. Overall, our findings shine a light on the potential of magnesium-based hydrogels as promising solutions for those dealing with osteoporosis-related bone damage.
Once injected, the hydrogel not only transforms into a supportive scaffold but also begins to release hydrogen and magnesium ions. This release is key in reducing harmful intracellular ROS and guiding the immune response favorably by promoting macrophage polarization. We observed that this gel suppressed the formation of osteoclasts, the cells responsible for bone resorption, while simultaneously encouraging the growth of new bone cells.
Animal experiments further illuminated the effectiveness of the magnesium-loaded hydrogel, showing a remarkable ability to enhance the repair of bone defects by controlling inflammation and supporting bone formation. Overall, our findings shine a light on the potential of magnesium-based hydrogels as promising solutions for those dealing with osteoporosis-related bone damage.
Read More
9
We explored the effects of a special material called magnesium-based zeolitic imidazolate frameworks, or Mg-ZIF, on osteoporosis. This study aimed to find a way to tackle osteoporosis by reducing reactive oxygen species (ROS)—harmful molecules that affect our bone health.
Our findings revealed that Mg-ZIF is effective at scavenging ROS, which helps boost the bone-forming ability of bone mesenchymal stem cells (BMSCs). By promoting osteogenic differentiation, Mg-ZIF supports the formation of new bone while simultaneously discouraging the development of fat cells from BMSCs, a process known as lipogenic differentiation.
In our in vivo experiments, we confirmed that administering Mg-ZIF could successfully lower ROS levels and mitigate the effects of osteoporosis. On a deeper level, the mechanism behind this involves Mg-ZIF enhancing BMSC differentiation into bone-forming cells by upregulating specific lipid metabolic pathways.
Overall, we believe that Mg-ZIF holds promise as a therapeutic approach for osteoporosis. By addressing the oxidative stress in the bone marrow environment, it opens a new door for potential treatments targeting this common bone disease.
Our findings revealed that Mg-ZIF is effective at scavenging ROS, which helps boost the bone-forming ability of bone mesenchymal stem cells (BMSCs). By promoting osteogenic differentiation, Mg-ZIF supports the formation of new bone while simultaneously discouraging the development of fat cells from BMSCs, a process known as lipogenic differentiation.
In our in vivo experiments, we confirmed that administering Mg-ZIF could successfully lower ROS levels and mitigate the effects of osteoporosis. On a deeper level, the mechanism behind this involves Mg-ZIF enhancing BMSC differentiation into bone-forming cells by upregulating specific lipid metabolic pathways.
Overall, we believe that Mg-ZIF holds promise as a therapeutic approach for osteoporosis. By addressing the oxidative stress in the bone marrow environment, it opens a new door for potential treatments targeting this common bone disease.
Read More
9
In our exploration of osteoporosis treatment, we focused on the effects of magnesium, particularly when combined with phosphorylated collagen peptide-magnesium chelates. Our study utilized osteoblast MC3T3-E1 cells and incorporated ovariectomized mice to simulate postmenopausal osteoporosis, which allowed us to see how magnesium might help in strengthening bones.
We observed that magnesium plays a vital role in bone health, especially in the context of osteoporosis. The results indicated that the combination treatment could enhance bone formation and improve overall bone density in our models. This suggests that magnesium, alongside other compounds, may offer a promising approach to managing osteoporosis.
However, it's important to note that while we found positive effects, the detailed mechanisms of how magnesium works in this specific treatment remain complex and may involve interactions with other components. Further research is needed to fully understand its efficacy and the best ways to integrate magnesium into osteoporosis treatment strategies.
We observed that magnesium plays a vital role in bone health, especially in the context of osteoporosis. The results indicated that the combination treatment could enhance bone formation and improve overall bone density in our models. This suggests that magnesium, alongside other compounds, may offer a promising approach to managing osteoporosis.
However, it's important to note that while we found positive effects, the detailed mechanisms of how magnesium works in this specific treatment remain complex and may involve interactions with other components. Further research is needed to fully understand its efficacy and the best ways to integrate magnesium into osteoporosis treatment strategies.
Read More
9
We explored a cutting-edge approach to tackle the challenges in repairing bones affected by osteoporosis. Drawing inspiration from the healing properties of hot springs, we created a unique calcium magnesium phosphate bone cement infused with manganese ions.
This innovative scaffold not only promotes the regeneration of neurovascular networks but also helps reduce harmful substances in the bone's environment. Our results indicate that this method significantly aids in bone healing, highlighting its potential for treating osteoporosis effectively.
This innovative scaffold not only promotes the regeneration of neurovascular networks but also helps reduce harmful substances in the bone's environment. Our results indicate that this method significantly aids in bone healing, highlighting its potential for treating osteoporosis effectively.
Read More
User Reviews
USERS' SCORE
Good
Based on 32 Reviews
8
- All Reviews
- Positive Reviews
- Negative Reviews
9
Muscle tension relief
I trust the quality of this magnesium product, which contains 500mg. It’s easy to consume, and the packaging is convenient. I find it effective in relieving muscle and nerve tension while also aiding in osteoporosis treatment.
Read More
9
Prevents muscle tension
An excellent supplement that should not be overlooked for preventing osteoporosis and muscle tension. It is advisable to take it at night. The product’s quality is outstanding, with sufficient magnesium per pill. It has no taste and is beneficial for bones and immunity, making it easy to consume.
Read More
9
Prevents Osteoporosis
By ensuring the correct mineralisation of bones, magnesium prevents the development of osteoporosis. It also helps regulate blood pressure and consequently reduces the risk of cardiovascular diseases. Additionally, it significantly strengthens the nervous system.
Read More
9
Maintains Bone Health
Magnesium is necessary for maintaining good bone health as it regulates calcium movement in the body and stimulates calcitonin secretion, promoting the influx of calcium into bone tissue. By ensuring the correct mineralisation of bones, it prevents the development of osteoporosis.
Read More
9
Increases Bone Density
Magnesium positively affects bone growth, normalises heart rate, lowers blood pressure, and alleviates muscle cramps and joint pain. It enhances bone mineral density when combined with calcium. A deficiency in magnesium can lead to osteoporosis, thus normalising magnesium levels can address insomnia, stress, and depression.
Read More
Frequently Asked Questions
9
Strengthens bones
This product is excellent! Suffering from Osteoporosis, I find magnesium greatly supports my bone health alongside calcium. It also benefits my cardiovascular system, which makes it doubly effective.
9
Maintains Bone Health
Magnesium is necessary for maintaining good bone health as it regulates calcium movement in the body and stimulates calcitonin secretion, promoting the influx of calcium into bone tissue. By ensuring the correct mineralisation of bones, it prevents the development of osteoporosis.
9
Muscle tension relief
I trust the quality of this magnesium product, which contains 500mg. It’s easy to consume, and the packaging is convenient. I find it effective in relieving muscle and nerve tension while also aiding in osteoporosis treatment.
9
Increases Bone Density
Magnesium positively affects bone growth, normalises heart rate, lowers blood pressure, and alleviates muscle cramps and joint pain. It enhances bone mineral density when combined with calcium. A deficiency in magnesium can lead to osteoporosis, thus normalising magnesium levels can address insomnia, stress, and depression.
7.5
Improves cardiovascular health
1 people found this helpful
I take magnesium to alleviate anxiety, depression, and stress. Regular magnesium consumption also helps mitigate the risk of osteoporosis and enhances cardiovascular functioning. It’s especially important for coffee drinkers, as this mineral is quickly lost from the body, leaving most people deficient. The capsules contain three forms of magnesium. Although large, they are easy to swallow and have a neutral taste.
7.5
Relieves pain
If you often experience back and leg pain due to Osteoporosis, using magnesium with calcium yields great effects!
7.5
Improves Bone Health
Magnesium is essential among trace minerals and is involved in over 300 reactions in the body. It plays a direct and indirect role in improving bone health as it regulates calcium and vitamin D levels, both crucial for bones. Consequently, it diminishes the risk of developing osteoporosis, especially in post-menopausal women.
8
We explored the connection between magnesium and osteoporosis by examining data from 2,115 participants. A variety of methods, including LASSO regression and logistic regression, were employed to analyze plasma concentrations of 22 different metals and their relationship with osteoporosis.
From our analysis, we found that magnesium plays a notable role in the likelihood of developing osteoporosis. Specifically, it was consistently associated with a reduced risk of this condition. In our findings, magnesium showed a negative correlation with osteoporosis, meaning higher levels of this essential mineral were linked to a lower chance of osteoporosis.
However, we also noted that exposure to metals like aluminum and cadmium was positively associated with an increased risk of osteoporosis, indicating that a combination of various metal exposures could influence bone health adversely. While magnesium appears to offer protective benefits, the interplay of different metals complicates the overall picture.
From our analysis, we found that magnesium plays a notable role in the likelihood of developing osteoporosis. Specifically, it was consistently associated with a reduced risk of this condition. In our findings, magnesium showed a negative correlation with osteoporosis, meaning higher levels of this essential mineral were linked to a lower chance of osteoporosis.
However, we also noted that exposure to metals like aluminum and cadmium was positively associated with an increased risk of osteoporosis, indicating that a combination of various metal exposures could influence bone health adversely. While magnesium appears to offer protective benefits, the interplay of different metals complicates the overall picture.
7
We explored the fascinating role of magnesium in osteoporosis, a condition that leads to weakened bones and increased fracture risk. Through our investigation, we observed that magnesium is vital for bone health and plays a significant part in bone formation and maintenance.
Magnesium deficiency can impact bone structure indirectly by interfering with calcium homeostasis. This interplay is orchestrated mainly through two key regulators: parathyroid hormone and vitamin D. Parathyroid hormone influences the production of essential proteins that regulate osteoclast formation, which is responsible for bone resorption.
We also learned that vitamin D works in tandem with magnesium to facilitate the balance between bone formation and resorption. When magnesium levels are low, this balance can tip in favor of bone loss, ultimately leading to osteoporosis. The RANK/RANKL/OPG signaling pathway is crucial in this context, as it governs the relationship between bone-building cells and those that break down bone.
Importantly, clinical studies indicate that magnesium supplementation may ease some symptoms of osteoporosis, although further research is needed to assess its effectiveness compared to other treatments. Overall, we understand that maintaining adequate magnesium levels is essential for bone health and may help prevent the progression of osteoporosis.
Magnesium deficiency can impact bone structure indirectly by interfering with calcium homeostasis. This interplay is orchestrated mainly through two key regulators: parathyroid hormone and vitamin D. Parathyroid hormone influences the production of essential proteins that regulate osteoclast formation, which is responsible for bone resorption.
We also learned that vitamin D works in tandem with magnesium to facilitate the balance between bone formation and resorption. When magnesium levels are low, this balance can tip in favor of bone loss, ultimately leading to osteoporosis. The RANK/RANKL/OPG signaling pathway is crucial in this context, as it governs the relationship between bone-building cells and those that break down bone.
Importantly, clinical studies indicate that magnesium supplementation may ease some symptoms of osteoporosis, although further research is needed to assess its effectiveness compared to other treatments. Overall, we understand that maintaining adequate magnesium levels is essential for bone health and may help prevent the progression of osteoporosis.
8
Magnesium enhances osteoporosis treatment
We explored how magnesium, along with other components, could address the challenges posed by osteoporosis. In this study, researchers developed a novel bone cement that incorporates magnesium oxide nanoparticles, aiming to enhance bone regeneration.
This innovative cement, known as C/AM-PL/C, demonstrated impressive mechanical strength and the ability to remain effective during injection. By releasing magnesium and calcium, the cement not only supported the growth of new blood vessels but also encouraged the differentiation of bone-forming cells.
Furthermore, the study highlighted that the cement could help inhibit the formation of bone-resorbing cells, providing a dual action beneficial for osteoporosis treatment. Especially noteworthy was how this cement improved healing in animal models with osteoporosis-related bone defects, showing promise as a treatment option for those suffering from this condition.
Overall, it appears that magnesium, when combined with other components in this novel cement, plays a significant role in encouraging bone healing and combatting the effects of osteoporosis.
This innovative cement, known as C/AM-PL/C, demonstrated impressive mechanical strength and the ability to remain effective during injection. By releasing magnesium and calcium, the cement not only supported the growth of new blood vessels but also encouraged the differentiation of bone-forming cells.
Furthermore, the study highlighted that the cement could help inhibit the formation of bone-resorbing cells, providing a dual action beneficial for osteoporosis treatment. Especially noteworthy was how this cement improved healing in animal models with osteoporosis-related bone defects, showing promise as a treatment option for those suffering from this condition.
Overall, it appears that magnesium, when combined with other components in this novel cement, plays a significant role in encouraging bone healing and combatting the effects of osteoporosis.
9
We delved into the use of a unique injectable hydrogel loaded with magnesium to address the challenges of repairing osteoporotic bone defects. The study aimed to understand how this magnesium-infused hydrogel could combat the excessive reactive oxygen species (ROS) that hinder bone repair. With impressive qualities such as excellent injectability and adaptability, the hydrogel can be introduced into irregular bone areas without the need for major surgery.
Once injected, the hydrogel not only transforms into a supportive scaffold but also begins to release hydrogen and magnesium ions. This release is key in reducing harmful intracellular ROS and guiding the immune response favorably by promoting macrophage polarization. We observed that this gel suppressed the formation of osteoclasts, the cells responsible for bone resorption, while simultaneously encouraging the growth of new bone cells.
Animal experiments further illuminated the effectiveness of the magnesium-loaded hydrogel, showing a remarkable ability to enhance the repair of bone defects by controlling inflammation and supporting bone formation. Overall, our findings shine a light on the potential of magnesium-based hydrogels as promising solutions for those dealing with osteoporosis-related bone damage.
Once injected, the hydrogel not only transforms into a supportive scaffold but also begins to release hydrogen and magnesium ions. This release is key in reducing harmful intracellular ROS and guiding the immune response favorably by promoting macrophage polarization. We observed that this gel suppressed the formation of osteoclasts, the cells responsible for bone resorption, while simultaneously encouraging the growth of new bone cells.
Animal experiments further illuminated the effectiveness of the magnesium-loaded hydrogel, showing a remarkable ability to enhance the repair of bone defects by controlling inflammation and supporting bone formation. Overall, our findings shine a light on the potential of magnesium-based hydrogels as promising solutions for those dealing with osteoporosis-related bone damage.
8
We aimed to understand how magnesium ascorbyl phosphate (MAP) might help with osteoporosis by promoting bone formation. In our findings, MAP significantly boosted the proliferation and differentiation of bone-forming cells in the lab. Additionally, when given as a supplement, it not only reduced bone loss but also aided in healing bone defects. The study pinpointed a key mechanism involving the activation of specific signaling pathways that MAP influences, emphasizing its potential as a promising treatment for osteoporosis.
9
In our exploration of osteoporosis treatment, we focused on the effects of magnesium, particularly when combined with phosphorylated collagen peptide-magnesium chelates. Our study utilized osteoblast MC3T3-E1 cells and incorporated ovariectomized mice to simulate postmenopausal osteoporosis, which allowed us to see how magnesium might help in strengthening bones.
We observed that magnesium plays a vital role in bone health, especially in the context of osteoporosis. The results indicated that the combination treatment could enhance bone formation and improve overall bone density in our models. This suggests that magnesium, alongside other compounds, may offer a promising approach to managing osteoporosis.
However, it's important to note that while we found positive effects, the detailed mechanisms of how magnesium works in this specific treatment remain complex and may involve interactions with other components. Further research is needed to fully understand its efficacy and the best ways to integrate magnesium into osteoporosis treatment strategies.
We observed that magnesium plays a vital role in bone health, especially in the context of osteoporosis. The results indicated that the combination treatment could enhance bone formation and improve overall bone density in our models. This suggests that magnesium, alongside other compounds, may offer a promising approach to managing osteoporosis.
However, it's important to note that while we found positive effects, the detailed mechanisms of how magnesium works in this specific treatment remain complex and may involve interactions with other components. Further research is needed to fully understand its efficacy and the best ways to integrate magnesium into osteoporosis treatment strategies.
7
Magnesium-enhanced treatment for osteoporosis
We examined how magnesium oxide nanoparticles (MgO NPs) synthesized from Hibiscus sabdariffa could help improve vitamin D and calcium levels in osteoporosis patients. In our study, 35 individuals with osteoporosis received MgO NPs, resulting in a significant boost in these essential nutrients compared to a control group of 25 healthy volunteers.
This suggests that using extracts of Hibiscus sabdariffa for magnesium supplementation holds promise in tackling osteoporosis. The study aimed at understanding the potential interactions with alkaline phosphatase also pointed to exciting possibilities for future research.
This suggests that using extracts of Hibiscus sabdariffa for magnesium supplementation holds promise in tackling osteoporosis. The study aimed at understanding the potential interactions with alkaline phosphatase also pointed to exciting possibilities for future research.
References
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- Li D, Dai D, Wang J, Zhang C. Honeycomb Bionic Graphene Oxide Quantum Dot/Layered Double Hydroxide Composite Nanocoating Promotes Osteoporotic Bone Regeneration via Activating Mitophagy. Small. 2024;20:e2403907. doi:10.1002/smll.202403907
- Zhou H, He Z, Cao Y, Chu L, Liang B, et al. An injectable magnesium-loaded hydrogel releases hydrogen to promote osteoporotic bone repair via ROS scavenging and immunomodulation. Theranostics. 2024;14:3739. doi:10.7150/thno.97412
- Liu L, Luo P, Wen P, Xu P. The role of magnesium in the pathogenesis of osteoporosis. Front Endocrinol (Lausanne). 2024;15:1406248. doi:10.3389/fendo.2024.1406248
- Huang L, Cai P, Bian M, Yu J, Xiao L, et al. Injectable and high-strength PLGA/CPC loaded ALN/MgO bone cement for bone regeneration by facilitating osteogenesis and inhibiting osteoclastogenesis in osteoporotic bone defects. Mater Today Bio. 2024;26:101092. doi:10.1016/j.mtbio.2024.101092
- Weng Z, Ye J, Cai C, Liu Z, Liu Y, et al. Inflammatory microenvironment regulation and osteogenesis promotion by bone-targeting calcium and magnesium repletion nanoplatform for osteoporosis therapy. J Nanobiotechnology. 2024;22:314. doi:10.1186/s12951-024-02581-7
- Dai Q, Wang Z, Liu C, Chen X, Cao X. High performance injectable Mg doped bioactive glass bone cement for the regulation of osteogenic immune microenvironment. Biomater Adv. 2024;160:213864. doi:10.1016/j.bioadv.2024.213864
- Li J, Chen Y, Zha D, Wu C, Li X, et al. Mg-ZIF nanozyme regulates the switch between osteogenic and lipogenic differentiation in BMSCs via lipid metabolism. Lipids Health Dis. 2024;23:88. doi:10.1186/s12944-024-02083-3
- Qin L, Liu Q, Zhang T, Tang X, Mo X, et al. Association Between Combined Polymetallic Exposure and Osteoporosis. Biol Trace Elem Res. 2024;202:3945. doi:10.1007/s12011-023-04002-6
- Ma T, Guan Y, Feng J, Yang Y, Chen J, et al. Osteogenic effect of magnesium oxychloride cement modified with phytic acid and loaded with strontium ranelate. Biomater Res. 2023;27:128. doi:10.1186/s40824-023-00474-8
- Zhang C, Du B, Deng G, Zhang S, Yu T, et al. Anti-osteoporosis properties of phosphorylated collagen peptide-magnesium chelates in osteoblast MC3T3-E1 cells and ovariectomized mice. Chin Med J (Engl). 2024;137:1762. doi:10.1097/CM9.0000000000002877
- Zhao Y, Liu J, Hu L, Yao X, Tu R, et al. Novel "hot spring"-mimetic scaffolds for sequential neurovascular network reconstruction and osteoporosis reversion. Biomaterials. 2025;320:123191. doi:10.1016/j.biomaterials.2025.123191
- Al-Garawi ZS, Al-Qaisi AHI, Al-Shamari KA, Öztürkkan FE, Necefoğlu H. The utility of Hibiscus sabdariffa L. to prepare metal oxides NPs for clinical application on osteoporosis supported by theoretical study. Bioprocess Biosyst Eng. 2024;47:753. doi:10.1007/s00449-024-03012-5
- Düğer H, Uçan B, Çalışkan M, Bostan H, Demirci T, et al. Hypomagnesemia may be associated with symptomatic disease in patients with primary hyperparathyroidism. Endocrine. 2024;83:466. doi:10.1007/s12020-023-03577-3
- Han H, Chen S, Wang X, Jin J, Li X, et al. Association of the composite dietary antioxidant index with bone mineral density in the United States general population: data from NHANES 2005-2010. J Bone Miner Metab. 2023;41:631. doi:10.1007/s00774-023-01438-7
- Zhu Y, Jia G, Yang Y, Weng J, Liu S, et al. Biomimetic Porous Magnesium Alloy Scaffolds Promote the Repair of Osteoporotic Bone Defects in Rats through Activating the Wnt/β-Catenin Signaling Pathway. ACS Biomater Sci Eng. 2023;9:3435. doi:10.1021/acsbiomaterials.2c01097
- Fouhy LE, Mangano KM, Zhang X, Hughes BD, Tucker KL, et al. Association between a Calcium-to-Magnesium Ratio and Osteoporosis among Puerto Rican Adults. J Nutr. 2023;153:2642. doi:10.1016/j.tjnut.2023.05.009
- Xie Y, Bao Z, Wang Z, Du D, Chen G, et al. Magnesium Ascorbyl Phosphate Promotes Bone Formation Via CaMKII Signaling. J Bone Miner Res. 2023;38:1015. doi:10.1002/jbmr.4820
- Salama RHM, Ali SS, Salama THM, Almged MA, Alsanory TA, et al. Dietary Effects of Nanopowder Eggshells on Mineral Contents, Bone Turnover Biomarkers, and Regulators of Bone Resorption in Healthy Rats and Ovariectomy-Induced Osteoporosis Rat Model. Appl Biochem Biotechnol. 2023;195:5034. doi:10.1007/s12010-022-04038-9
