We examined the role of N-acetylcysteine (NAC) in treating cough, particularly among patients with Chronic Obstructive Pulmonary Disease (COPD). This treatment approach falls under the broader framework of the treatable traits strategy, which focuses on identifying and managing specific symptoms that significantly impact patients' lives.
Our findings highlighted NAC's well-established effectiveness as a mucolytic agent, meaning it helps break down mucus in the airways, which can alleviate persistent cough. However, we observed that NAC does not just target coughing alone; it also may have broader benefits for various clinical traits associated with COPD, such as airflow limitation and lung inflammation.
Nevertheless, the isolated effects of NAC strictly on cough treatment can be hard to discern due to these overlapping factors. In some cases, NAC has shown promise in improving symptoms and overall quality of life for COPD patients, suggesting it could be an important component of a personalized treatment plan.
Overall, NAC may not only target cough effectively but also plays a role in managing other serious symptoms of COPD, which makes it a valuable option for those seeking relief from this challenging condition.
Read More
8
NAC aids cough relief in pneumonia
Effects of N-Acetylcysteine combined with Ambroxol Hydrochloride on clinical symptoms, CRP, and PCT in children with pneumonia.
We explored the effectiveness of N-Acetylcysteine (NAC) in combination with Ambroxol Hydrochloride (AH) on relieving cough in children with pneumonia. In this study, 98 children were divided into two groups: the observation group, which received NAC, and the control group, which was given AH alone.
The results revealed that the time until cough symptoms disappeared was significantly shorter in the observation group compared to the control group. This suggests that NAC plays a valuable role in alleviating cough among young patients suffering from pneumonia.
Additionally, our findings indicated improvements in overall lung function and reductions in inflammation markers like C-Reactive Protein (CRP) and Procalcitonin (PCT) in the children treated with NAC. This provides us with compelling evidence of how NAC can positively influence respiratory symptoms.
Importantly, the side effects observed in both groups were minimal and not significantly different from one another. Overall, NAC combined with AH appears to be an effective treatment option for addressing cough and other related symptoms in pediatric pneumonia.
Read More
Most Useful Reviews
9
Helps cope with cough
196 people found this helpful
It helps me cope with a cough. Overall, for any cold, it's a good remedy. I recommend it.
Read More
7.5
Improves cough relief
164 people found this helpful
I really appreciate this version of the product. It acts quickly on coughs and aids the liver. Amino acids saturate the body, enhancing overall health. I recommend it.
Read More
10
Effective for cough
103 people found this helpful
This medication is quite effective. It eradicates sputum and cough within 5-7 days, leaving no traces of the illness. It has a sour taste, reminiscent of ACC, and is a commendable substitute. I suggest everyone give it a try, but be aware of contraindications!
We examined the role of N-acetylcysteine (NAC) in treating cough, particularly among patients with Chronic Obstructive Pulmonary Disease (COPD). This treatment approach falls under the broader framework of the treatable traits strategy, which focuses on identifying and managing specific symptoms that significantly impact patients' lives.
Our findings highlighted NAC's well-established effectiveness as a mucolytic agent, meaning it helps break down mucus in the airways, which can alleviate persistent cough. However, we observed that NAC does not just target coughing alone; it also may have broader benefits for various clinical traits associated with COPD, such as airflow limitation and lung inflammation.
Nevertheless, the isolated effects of NAC strictly on cough treatment can be hard to discern due to these overlapping factors. In some cases, NAC has shown promise in improving symptoms and overall quality of life for COPD patients, suggesting it could be an important component of a personalized treatment plan.
Overall, NAC may not only target cough effectively but also plays a role in managing other serious symptoms of COPD, which makes it a valuable option for those seeking relief from this challenging condition.
Read More
8
NAC aids cough relief in pneumonia
Effects of N-Acetylcysteine combined with Ambroxol Hydrochloride on clinical symptoms, CRP, and PCT in children with pneumonia.
We explored the effectiveness of N-Acetylcysteine (NAC) in combination with Ambroxol Hydrochloride (AH) on relieving cough in children with pneumonia. In this study, 98 children were divided into two groups: the observation group, which received NAC, and the control group, which was given AH alone.
The results revealed that the time until cough symptoms disappeared was significantly shorter in the observation group compared to the control group. This suggests that NAC plays a valuable role in alleviating cough among young patients suffering from pneumonia.
Additionally, our findings indicated improvements in overall lung function and reductions in inflammation markers like C-Reactive Protein (CRP) and Procalcitonin (PCT) in the children treated with NAC. This provides us with compelling evidence of how NAC can positively influence respiratory symptoms.
Importantly, the side effects observed in both groups were minimal and not significantly different from one another. Overall, NAC combined with AH appears to be an effective treatment option for addressing cough and other related symptoms in pediatric pneumonia.
Read More
User Reviews
USERS' SCORE
Good
Based on 463 Reviews
8.3
All Reviews
Positive Reviews
Negative Reviews
9
Helps cope with cough
196 people found this helpful
It helps me cope with a cough. Overall, for any cold, it's a good remedy. I recommend it.
Read More
7.5
Improves cough relief
164 people found this helpful
I really appreciate this version of the product. It acts quickly on coughs and aids the liver. Amino acids saturate the body, enhancing overall health. I recommend it.
Read More
10
Effective for cough
103 people found this helpful
This medication is quite effective. It eradicates sputum and cough within 5-7 days, leaving no traces of the illness. It has a sour taste, reminiscent of ACC, and is a commendable substitute. I suggest everyone give it a try, but be aware of contraindications!
Read More
9
Mucolytic effect
94 people found this helpful
I have previously discussed the importance of ACC. N-Acetyl L-Cysteine is an amino acid with mucolytic coughing action, diluting phlegm, even purulent sputum, which aids in expelling it. It also has antioxidant properties, removing harmful free radicals and benefiting organ health. It’s cost-effective compared to other ACC options. I recommend it!
Coughing is a reflex action that helps clear the airways of mucus, irritants, or foreign particles. It is a natural mechanism the body uses to protect itself and can be triggered by various factors, including infections, allergies, or environmental irritants. There are two main types of coughs: acute coughs, which typically last less than three weeks and often result from a cold or respiratory infection, and chronic coughs, which persist for more than eight weeks and may indicate a more serious underlying condition.
Coughs can also be classified as dry or productive. A dry cough does not produce mucus, while a productive cough does. Treatment options depend on the underlying cause; over-the-counter medications, home remedies, or medical intervention may be recommended based on the severity and duration of the cough. If a cough is persistent, accompanied by other symptoms like fever, shortness of breath, or chest pain, it’s advisable to seek medical advice for a proper diagnosis and treatment plan.
N-Acetyl Cysteine (NAC) is a modified form of the amino acid cysteine, known for its role as a powerful antioxidant and mucolytic agent. It has been widely used as a dietary supplement for various health benefits, including supporting respiratory health, detoxification, and enhancing overall immune function. NAC is particularly recognized for its ability to replenish glutathione, one of the body's most important antioxidants, which helps combat oxidative stress and protect cells from damage.
In addition to its antioxidant properties, N-Acetyl Cysteine is commonly leveraged in a clinical setting for its effectiveness in treating acetaminophen (Tylenol) overdoses, as it aids in restoring depleted glutathione levels, thus preventing liver damage. It can also be beneficial for individuals with chronic respiratory conditions, such as COPD or cystic fibrosis, as it helps in thinning mucus, making it easier to expel. While NAC is generally considered safe for most people, it’s important to consult a healthcare professional before starting any new supplement, particularly for those with pre-existing conditions or those already on medication.
Based on user reviews, the timing for seeing results from this supplement when used for cough varies, but many users seem to experience relief within a week to ten days. For instance, one user reported that their cough diminished significantly after just a week of use, while another mentioned resolution of a persistent cough following COVID after 7 to 10 days of treatment Read Review.
Additionally, several users have reported that more chronic coughs and associated phlegm improved significantly after about 5 to 7 days, indicating that this product may be quite effective in promoting relief quickly Read Review. Nevertheless, some reviewers suggested that consistent use, possibly over a month, can provide more comprehensive benefits, especially for those recovering from illnesses like bronchitis or COVID Read Review. In summary, while individual experiences may vary, users generally seem to observe benefits in the range of one week to ten days.
N-acetylcysteine (NAC) is increasingly recognized in scientific research for its potential to alleviate cough symptoms in various patient populations. A study focused on chronic obstructive pulmonary disease (COPD) patients highlighted NAC's effectiveness as a mucolytic agent that helps break down mucus in the airways, leading to cough relief. While the study emphasized that NAC targets broader symptoms associated with COPD, its role in managing cough specifically underscores its value as part of a comprehensive treatment strategy for those grappling with the effects of this chronic condition [1].
Furthermore, research has demonstrated NAC's efficacy in pediatric patients suffering from pneumonia, where it was shown to significantly reduce the duration of cough symptoms when used in conjunction with Ambroxol Hydrochloride. In this instance, the study provided promising evidence that NAC not only aids in cough relief but also contributes to enhancing overall lung function and reducing inflammation markers, making it a compelling option for treating cough in children [2]. Overall, NAC is well-supported by scientific research as a viable supplement for managing cough across different age groups and respiratory conditions.
Users have reported a range of improvements in their symptoms after using this product, with many noting significant relief from persistent coughs and phlegm. For instance, one user highlighted the effectiveness of the medication, stating that it eradicated sputum and cough within 5 to 7 days Read Review. Another review emphasized the product's quick action, describing how it cleared up coughs and supporting overall health Read Review.
Several users shared experiences suggesting that the product facilitated phlegm expulsion and significantly eased cough symptoms, with reports of improvement after just one week of use Read Review. One reviewer mentioned a remarkable recovery from a persistent cough that had lasted for three months, with symptoms declining notably within a week of starting the supplement Read Review. Another user dealing with bronchitis found that the product made phlegm easier to manage, leading to a rapid cessation of coughing Read Review. While these anecdotal experiences are promising, it's essential to note that individual results may vary.
Based on user reviews, there are mixed experiences regarding the combination of this supplement with other products for managing cough symptoms. Some users found success using this supplement in conjunction with other medications, reporting significant relief from chronic coughs over time. For instance, one reviewer indicated that while they were uncertain whether their improvement was due solely to this supplement or a combination with other treatments, they experienced a marked reduction in their persistent cough within a week of starting it Read Review. This suggests that users may benefit from integrating it with additional support during treatment, particularly for stubborn coughs.
Conversely, other users underscored the importance of using this supplement alone to optimize its effects and reduce potential interactions with other medications. One review emphasized that if a cough isn't present, it may be best not to use the supplement, indicating that targeting treatment specifically can lead to more effective results Read Review. Overall, while some users advocate for a multi-faceted approach in managing cough symptoms, others suggest a more focused strategy might be advantageous for achieving the best results.
Users report that N-Acetyl Cysteine (NAC) can be effective for treating coughs and related symptoms. The suggested dosage varies among users, but many mention taking a consistent daily amount. For example, one user reported taking one capsule twice daily Read Review while another mentioned starting with two capsules daily for a week before reducing to one per day Read Review. Users noted significant improvement in cough and sputum production after about one to two weeks of use Read Review, suggesting that maintaining the recommended dosage for a period may enhance its effectiveness.
Additionally, several reviews highlight the importance of ongoing usage during lengthy illnesses, particularly after infections such as COVID-19 Read Review. It's also advised to consult a healthcare professional for guidance on dosage and potential contraindications Read Review. Overall, while users share positive experiences with NAC in relieving coughs, they underscore the need for proper dosing and medical advice tailored to individual health needs.
9
Post-COVID solution
49 people found this helpful
I am very fond of this product, my consistent purchase. In Autumn 2020, it helped me recover from a persistent cough following COVID, resolving in 7 to 10 days. Cysteine is an essential amino acid, acting as an antioxidant and reducing harmful homocysteine in the blood.
10
Effective for cough
103 people found this helpful
This medication is quite effective. It eradicates sputum and cough within 5-7 days, leaving no traces of the illness. It has a sour taste, reminiscent of ACC, and is a commendable substitute. I suggest everyone give it a try, but be aware of contraindications!
9
Effective tasks
10 people found this helpful
Life Extension, N-acetyl-L-cysteine, 600 mg, 60 capsules effectively removes phlegm and promotes hair growth. I take two tablets a day; initially, coughing attacks occurred as the phlegm started to clear. After a week, the cough disappeared. Even after running or laughing for a prolonged period, I previously experienced a cough, but after a month of use, it was resolved. The supplement fulfilled its duties admirably.
7.5
Improves cough relief
164 people found this helpful
I really appreciate this version of the product. It acts quickly on coughs and aids the liver. Amino acids saturate the body, enhancing overall health. I recommend it.
9
Cough vanished
6 people found this helpful
I’m not sure if this medication was solely responsible or if it worked in conjunction with something else, but after three months of a persistent cough, it started to lessen significantly a week after I began taking it, and eventually it disappeared altogether. I managed fine without an inhaler, possibly thanks to this medication.
9
Bronchitis treated well
54 people found this helpful
She fell very ill with bronchitis, experiencing a cough with hard-to-separate phlegm. The doctor prescribed ADC, but I chose the best option here instead. It effectively improves health, making bronchitis easier to manage and facilitating phlegm removal. After taking it, the cough ceased. Remember to stay hydrated and take medication only under doctor's guidance!
9
Gradual cough relief
2 people found this helpful
It works excellently for coughing. Take one pill daily, and gradually the cough will lessen. However, if you don’t have a cough, it's best not to use it.
10
Essential remedy
4 people found this helpful
Acetylcysteine is an indispensable mucolytic, expectorant, and antioxidant. It is recommended for infectious diseases associated with viscous sputum formation, including various respiratory ailments. It should be included in every first aid kit! I take 1 capsule twice daily, preferably before meals. If you find my review helpful, please give it a LIKE!
10
Cleared cough
4 people found this helpful
I had tracheitis, and the nebuliser and the Russian ACC proved unhelpful. I often coughed for 2-3 months due to residual tracheitis. I purchased this drug urgently and initially took 2 capsules daily for a week, then 1 per day for another week. Within just two weeks, the trachea was cleared, and both the cough and heaviness in my chest ceased. I do not smoke.
8
NAC may effectively ease COPD cough
The precision medicine strategy to treat COPD pulmonary traits in clinical practice: The role of N-acetylcysteine.
We examined the role of N-acetylcysteine (NAC) in treating cough, particularly among patients with Chronic Obstructive Pulmonary Disease (COPD). This treatment approach falls under the broader framework of the treatable traits strategy, which focuses on identifying and managing specific symptoms that significantly impact patients' lives.
Our findings highlighted NAC's well-established effectiveness as a mucolytic agent, meaning it helps break down mucus in the airways, which can alleviate persistent cough. However, we observed that NAC does not just target coughing alone; it also may have broader benefits for various clinical traits associated with COPD, such as airflow limitation and lung inflammation.
Nevertheless, the isolated effects of NAC strictly on cough treatment can be hard to discern due to these overlapping factors. In some cases, NAC has shown promise in improving symptoms and overall quality of life for COPD patients, suggesting it could be an important component of a personalized treatment plan.
Overall, NAC may not only target cough effectively but also plays a role in managing other serious symptoms of COPD, which makes it a valuable option for those seeking relief from this challenging condition.
8
NAC aids cough relief in pneumonia
Effects of N-Acetylcysteine combined with Ambroxol Hydrochloride on clinical symptoms, CRP, and PCT in children with pneumonia.
We explored the effectiveness of N-Acetylcysteine (NAC) in combination with Ambroxol Hydrochloride (AH) on relieving cough in children with pneumonia. In this study, 98 children were divided into two groups: the observation group, which received NAC, and the control group, which was given AH alone.
The results revealed that the time until cough symptoms disappeared was significantly shorter in the observation group compared to the control group. This suggests that NAC plays a valuable role in alleviating cough among young patients suffering from pneumonia.
Additionally, our findings indicated improvements in overall lung function and reductions in inflammation markers like C-Reactive Protein (CRP) and Procalcitonin (PCT) in the children treated with NAC. This provides us with compelling evidence of how NAC can positively influence respiratory symptoms.
Importantly, the side effects observed in both groups were minimal and not significantly different from one another. Overall, NAC combined with AH appears to be an effective treatment option for addressing cough and other related symptoms in pediatric pneumonia.
References
Scioscia G, Baraldi F, Bigoni T, Papi A, Vatrella A, et al. The precision medicine strategy to treat COPD pulmonary traits in clinical practice: The role of N-acetylcysteine. Respir Med. 2024;235:107865. doi:10.1016/j.rmed.2024.107865
Xue A, Zhang H, Song S, Yu X. Effects of N-Acetylcysteine combined with Ambroxol Hydrochloride on clinical symptoms, CRP, and PCT in children with pneumonia. Clinics (Sao Paulo). 2024;79:100476. doi:10.1016/j.clinsp.2024.100476