'
SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
USERS' SCORE
Good
Based on 3 Reviews
8.7
Supplement Facts
Serving Size: 1 Capsule
Amount Per Serving
%DV
N-acetyl-L-cysteine
600 mg
**

Top Medical Research Studies

8
NAC may effectively ease COPD cough
The precision medicine strategy to treat COPD pulmonary traits in clinical practice: The role of N-acetylcysteine.
Study shows mixed treatment benefits
We examined the role of N-acetylcysteine (NAC) in treating cough, particularly among patients with Chronic Obstructive Pulmonary Disease (COPD). This treatment approach falls under the broader framework of the treatable traits strategy, which focuses on identifying and managing specific symptoms that significantly impact patients' lives.

Our findings highlighted NAC's well-established effectiveness as a mucolytic agent, meaning it helps break down mucus in the airways, which can alleviate persistent cough. However, we observed that NAC does not just target coughing alone; it also may have broader benefits for various clinical traits associated with COPD, such as airflow limitation and lung inflammation.

Nevertheless, the isolated effects of NAC strictly on cough treatment can be hard to discern due to these overlapping factors. In some cases, NAC has shown promise in improving symptoms and overall quality of life for COPD patients, suggesting it could be an important component of a personalized treatment plan.

Overall, NAC may not only target cough effectively but also plays a role in managing other serious symptoms of COPD, which makes it a valuable option for those seeking relief from this challenging condition.
Read More
8
NAC aids cough relief in pneumonia
Effects of N-Acetylcysteine combined with Ambroxol Hydrochloride on clinical symptoms, CRP, and PCT in children with pneumonia.
Combination therapy evaluated
We explored the effectiveness of N-Acetylcysteine (NAC) in combination with Ambroxol Hydrochloride (AH) on relieving cough in children with pneumonia. In this study, 98 children were divided into two groups: the observation group, which received NAC, and the control group, which was given AH alone.

The results revealed that the time until cough symptoms disappeared was significantly shorter in the observation group compared to the control group. This suggests that NAC plays a valuable role in alleviating cough among young patients suffering from pneumonia.

Additionally, our findings indicated improvements in overall lung function and reductions in inflammation markers like C-Reactive Protein (CRP) and Procalcitonin (PCT) in the children treated with NAC. This provides us with compelling evidence of how NAC can positively influence respiratory symptoms.

Importantly, the side effects observed in both groups were minimal and not significantly different from one another. Overall, NAC combined with AH appears to be an effective treatment option for addressing cough and other related symptoms in pediatric pneumonia.
Read More

Most Useful Reviews

9.5
Cough relief noted
Cough, cough, cough. Having asthma, a cold produces a nonproductive cough that lingers. When I remember to take N-Acetyl L-Cycteine, it breaks the cough up in a couple of days. Life Extension is a wonderful lab, and I've loved their products even during my years as a member. While I can't afford membership anymore, it’s good these products are now available on Amazon!
Read More
9.5
Effectively shortens cold
Great for shortening a cold. I bought this in anticipation of the cold and flu season and had to use it sooner than expected when I caught my husband's cold. On 1/31, I felt sick and by the next day, I was fully congested with a cough. I started taking 600mg twice a day on 2/1, and by 2/5 I felt much better! Normally, a cold leads to a weeks-long upper respiratory infection for me, but this time the mucus was expelled easily, preventing any infection requiring antibiotics. I managed to go out on 2/9 feeling well—kicking a cold in a little over a week is a record for me! I'm hooked on NAC!
Read More
8.8
Reduces smoker's cough
Great product. I initially bought this as an experiment to see if it would prevent hangovers as claimed by a Finnish study. While I didn't notice any effects regarding hangovers, I've found my smoker's cough is almost nonexistent. I also struggle with depression and anxiety and have seen an improvement in my mood. Research suggests that inflammation greatly contributes to mental health disorders, and this NAC seems to combat that. Overall, I’m very impressed and recommend it to others.
Read More

Medical Researches

SCIENTIFIC SCORE
Moderately Effective
Based on 2 Researches
8
8
NAC may effectively ease COPD cough
The precision medicine strategy to treat COPD pulmonary traits in clinical practice: The role of N-acetylcysteine.
Study shows mixed treatment benefits
We examined the role of N-acetylcysteine (NAC) in treating cough, particularly among patients with Chronic Obstructive Pulmonary Disease (COPD). This treatment approach falls under the broader framework of the treatable traits strategy, which focuses on identifying and managing specific symptoms that significantly impact patients' lives.

Our findings highlighted NAC's well-established effectiveness as a mucolytic agent, meaning it helps break down mucus in the airways, which can alleviate persistent cough. However, we observed that NAC does not just target coughing alone; it also may have broader benefits for various clinical traits associated with COPD, such as airflow limitation and lung inflammation.

Nevertheless, the isolated effects of NAC strictly on cough treatment can be hard to discern due to these overlapping factors. In some cases, NAC has shown promise in improving symptoms and overall quality of life for COPD patients, suggesting it could be an important component of a personalized treatment plan.

Overall, NAC may not only target cough effectively but also plays a role in managing other serious symptoms of COPD, which makes it a valuable option for those seeking relief from this challenging condition.
Read More
8
NAC aids cough relief in pneumonia
Effects of N-Acetylcysteine combined with Ambroxol Hydrochloride on clinical symptoms, CRP, and PCT in children with pneumonia.
Combination therapy evaluated
We explored the effectiveness of N-Acetylcysteine (NAC) in combination with Ambroxol Hydrochloride (AH) on relieving cough in children with pneumonia. In this study, 98 children were divided into two groups: the observation group, which received NAC, and the control group, which was given AH alone.

The results revealed that the time until cough symptoms disappeared was significantly shorter in the observation group compared to the control group. This suggests that NAC plays a valuable role in alleviating cough among young patients suffering from pneumonia.

Additionally, our findings indicated improvements in overall lung function and reductions in inflammation markers like C-Reactive Protein (CRP) and Procalcitonin (PCT) in the children treated with NAC. This provides us with compelling evidence of how NAC can positively influence respiratory symptoms.

Importantly, the side effects observed in both groups were minimal and not significantly different from one another. Overall, NAC combined with AH appears to be an effective treatment option for addressing cough and other related symptoms in pediatric pneumonia.
Read More

User Reviews

USERS' SCORE
Good
Based on 3 Reviews
8.7
9.5
Effectively shortens cold
Great for shortening a cold. I bought this in anticipation of the cold and flu season and had to use it sooner than expected when I caught my husband's cold. On 1/31, I felt sick and by the next day, I was fully congested with a cough. I started taking 600mg twice a day on 2/1, and by 2/5 I felt much better! Normally, a cold leads to a weeks-long upper respiratory infection for me, but this time the mucus was expelled easily, preventing any infection requiring antibiotics. I managed to go out on 2/9 feeling well—kicking a cold in a little over a week is a record for me! I'm hooked on NAC!
Read More
9.5
Cough relief noted
Cough, cough, cough. Having asthma, a cold produces a nonproductive cough that lingers. When I remember to take N-Acetyl L-Cycteine, it breaks the cough up in a couple of days. Life Extension is a wonderful lab, and I've loved their products even during my years as a member. While I can't afford membership anymore, it’s good these products are now available on Amazon!
Read More
8.8
Reduces smoker's cough
Great product. I initially bought this as an experiment to see if it would prevent hangovers as claimed by a Finnish study. While I didn't notice any effects regarding hangovers, I've found my smoker's cough is almost nonexistent. I also struggle with depression and anxiety and have seen an improvement in my mood. Research suggests that inflammation greatly contributes to mental health disorders, and this NAC seems to combat that. Overall, I’m very impressed and recommend it to others.
Read More
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