Overview
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.5
USERS' SCORE
Moderately Good
Based on 16 Reviews
7.3
Supplement Facts
Serving Size: 3 Vegetarian Capsules
Amount Per Serving
%DV
Magnesium (from 2,000 mg Magtein® magnesium L-threonate)
144 mg
34%
Top Medical Research Studies
8
Magnesium scaffold shows promising results
We investigated the clinical safety and performance of a new magnesium scaffold known as DREAMS 3G. This innovative treatment aims to match the effectiveness of drug-eluting stents in coronary interventions.
Over one year, a total of 116 patients were monitored, showing promising results with minimal lumen loss and no adverse events like cardiac death or major thrombosis. Despite a few revascularization interventions, the scaffold appears to be a viable alternative.
Overall, our findings support its potential use in heart treatments.
Over one year, a total of 116 patients were monitored, showing promising results with minimal lumen loss and no adverse events like cardiac death or major thrombosis. Despite a few revascularization interventions, the scaffold appears to be a viable alternative.
Overall, our findings support its potential use in heart treatments.
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9
We investigated the effects of magnesium oxide nanoparticles, created using fruit extract, on blood clotting and oxidative stress. Our experiments showed that these nanoparticles significantly extended clotting time, indicating an anticoagulant effect. They also effectively reduced damage to red blood cells and various tissues in laboratory tests, helping to restore their function. Importantly, we found these nanoparticles non-toxic, suggesting they could be a promising treatment option for oxidative stress-related conditions without adverse side effects. However, further research is needed to fully understand their potential in clinical applications.
Read More
8
We aimed to examine how bioresorbable magnesium scaffolds influence blood clotting. Using a cutting-edge stent flow chamber system, we compared the thrombogenicity of various stents, including the Magmaris magnesium scaffold and a prototype called DREAMS 3G.
Our findings indicated that the Magmaris scaffold exhibited significantly lower thrombogenicity than traditional stainless steel stents. Impressively, the DREAMS 3G prototype demonstrated even further reductions in clotting risks, suggesting it could enhance patient safety.
This study highlights the potential of magnesium-based scaffolds in improving cardiovascular treatments.
Our findings indicated that the Magmaris scaffold exhibited significantly lower thrombogenicity than traditional stainless steel stents. Impressively, the DREAMS 3G prototype demonstrated even further reductions in clotting risks, suggesting it could enhance patient safety.
This study highlights the potential of magnesium-based scaffolds in improving cardiovascular treatments.
Read More
Most Useful Reviews
9
Soothing effects
5 people found this helpful
The best form of magnesium. It’s the only type that penetrates the blood-brain barrier and enhances memory and mental capabilities, besides being quite soothing. During a challenging training phase, combined with omega 3, lecithin, and a B-complex, my thinking improved significantly, and I was surprised by the boost in my memory.
Read More
9
Fast relief
1 people found this helpful
It works. There’s no doubt in my mind that it effectively crosses the blood-brain barrier. Upon arrival, I was hungover from a night out. Moments after taking 2 capsules, my brain felt considerably better, and the ache receded. I'm very impressed. Life Extension's quality is excellent. The capsule size may be a challenge for someone with a poor swallow reflex, but they can be opened and sprinkled on food. I plan to take 300-400 mg daily now and feel more energetic and alive.
Read More
7.5
Effective under stress
The quality is superb, and the capsule size is manageable. This magnesium effectively crosses the blood-brain barrier, reaching the brain. It works exceptionally well during periods of severe stress; I recommend using it in the evening. The taste is neutral. Thank you for your appreciation.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.5
- All Researches
9
We investigated the effects of magnesium oxide nanoparticles, created using fruit extract, on blood clotting and oxidative stress. Our experiments showed that these nanoparticles significantly extended clotting time, indicating an anticoagulant effect. They also effectively reduced damage to red blood cells and various tissues in laboratory tests, helping to restore their function. Importantly, we found these nanoparticles non-toxic, suggesting they could be a promising treatment option for oxidative stress-related conditions without adverse side effects. However, further research is needed to fully understand their potential in clinical applications.
Read More
8
We explored whether magnesium intake could influence the risk of retinal vein occlusion (RVO), a leading cause of vision loss. Our analysis involved over 16,000 participants from a national health survey.
We discovered that sufficient magnesium intake was linked to a significant 64% reduced risk of RVO.
This finding was especially relevant for adults under 60, those with hypertension, and individuals without glaucoma. Further studies are needed to confirm magnesium's preventive benefits for RVO.
We discovered that sufficient magnesium intake was linked to a significant 64% reduced risk of RVO.
This finding was especially relevant for adults under 60, those with hypertension, and individuals without glaucoma. Further studies are needed to confirm magnesium's preventive benefits for RVO.
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8
Effective clay-based hemostatic sponge
We examined a new sponge made from clay and collagen to control severe bleeding. Integrating palygorskite clay with collagen using gallic acid created a sponge that resists particle shedding and provides strong adhesion.
In our tests, this sponge demonstrated impressive results, reducing blood loss to 632 mg and achieving hemostasis in just 151 seconds, outperforming traditional gauze and even a well-known product called QuikClot.
With added antibacterial and antioxidant properties, this sponge could significantly enhance emergency bleeding management.
In our tests, this sponge demonstrated impressive results, reducing blood loss to 632 mg and achieving hemostasis in just 151 seconds, outperforming traditional gauze and even a well-known product called QuikClot.
With added antibacterial and antioxidant properties, this sponge could significantly enhance emergency bleeding management.
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8
We aimed to examine how bioresorbable magnesium scaffolds influence blood clotting. Using a cutting-edge stent flow chamber system, we compared the thrombogenicity of various stents, including the Magmaris magnesium scaffold and a prototype called DREAMS 3G.
Our findings indicated that the Magmaris scaffold exhibited significantly lower thrombogenicity than traditional stainless steel stents. Impressively, the DREAMS 3G prototype demonstrated even further reductions in clotting risks, suggesting it could enhance patient safety.
This study highlights the potential of magnesium-based scaffolds in improving cardiovascular treatments.
Our findings indicated that the Magmaris scaffold exhibited significantly lower thrombogenicity than traditional stainless steel stents. Impressively, the DREAMS 3G prototype demonstrated even further reductions in clotting risks, suggesting it could enhance patient safety.
This study highlights the potential of magnesium-based scaffolds in improving cardiovascular treatments.
Read More
8
Bioresorbable stents' advancements noted
We explored the evolution of bioresorbable metallic stents as alternatives to traditional stents which can lead to complications like thrombosis and inflammation.
While bioresorbable polymeric stents face challenges, materials like zinc and magnesium show promise.
Specifically, magnesium-based stents have demonstrated successful absorption within a year and low rates of complications.
Continuing research will be essential to refine these innovations for better clinical outcomes.
While bioresorbable polymeric stents face challenges, materials like zinc and magnesium show promise.
Specifically, magnesium-based stents have demonstrated successful absorption within a year and low rates of complications.
Continuing research will be essential to refine these innovations for better clinical outcomes.
Read More
User Reviews
USERS' SCORE
Moderately Good
Based on 16 Reviews
7.3
- All Reviews
- Positive Reviews
- Negative Reviews
9
Soothing effects
5 people found this helpful
The best form of magnesium. It’s the only type that penetrates the blood-brain barrier and enhances memory and mental capabilities, besides being quite soothing. During a challenging training phase, combined with omega 3, lecithin, and a B-complex, my thinking improved significantly, and I was surprised by the boost in my memory.
Read More
9
Fast relief
1 people found this helpful
It works. There’s no doubt in my mind that it effectively crosses the blood-brain barrier. Upon arrival, I was hungover from a night out. Moments after taking 2 capsules, my brain felt considerably better, and the ache receded. I'm very impressed. Life Extension's quality is excellent. The capsule size may be a challenge for someone with a poor swallow reflex, but they can be opened and sprinkled on food. I plan to take 300-400 mg daily now and feel more energetic and alive.
Read More
7.5
Effective under stress
The quality is superb, and the capsule size is manageable. This magnesium effectively crosses the blood-brain barrier, reaching the brain. It works exceptionally well during periods of severe stress; I recommend using it in the evening. The taste is neutral. Thank you for your appreciation.
Read More
6
Calming effects experienced
17 people found this helpful
I chose this magnesium in response to unpleasant neurological symptoms from low blood sugar. Initially using other types relieved my hypoglycemics, yet anxiety lingered. Upon learning this magnesium reaches the brain, I incorporated it alongside my existing regimen. About 30 minutes after taking it, I reach a remarkably calm state, and I rely on it before stressful moments. It's now a regular part of my health management.
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9
Enhanced learning
10 people found this helpful
Magnesium for the brain🧠. I purchased this magnesium for my daughter as well. This form crosses the blood-brain barrier and aids mental activity and memorisation, which has shown results. I found a way to give the capsule to my child by mixing it in yoghurt since the pills aren't very palatable for little ones.
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Frequently Asked Questions
6
Calming effects experienced
17 people found this helpful
I chose this magnesium in response to unpleasant neurological symptoms from low blood sugar. Initially using other types relieved my hypoglycemics, yet anxiety lingered. Upon learning this magnesium reaches the brain, I incorporated it alongside my existing regimen. About 30 minutes after taking it, I reach a remarkably calm state, and I rely on it before stressful moments. It's now a regular part of my health management.
4
Concentration improved
1 people found this helpful
This quality magnesium L-Threonate comes highly recommended. It’s best taken with meals for quicker effects, and you can take it at any time of the day. After three weeks, I noticed my concentration returning, though I can’t confirm improvement in memory yet. However, I believe these benefits will come with time.
7.5
Calmness achieved
2 people found this helpful
Magnesium was prescribed for my 6-year-old based on trace element analysis results. Initially prescribed 3 tablets daily, after having loose stools, it was reduced to 1 tablet, normalising the stool. My child became calmer and more focused after just a week of taking magnesium l-threonate, which is the only type that crosses the blood-brain barrier and is rapidly absorbed by the brain.
9
Soothing effects
5 people found this helpful
The best form of magnesium. It’s the only type that penetrates the blood-brain barrier and enhances memory and mental capabilities, besides being quite soothing. During a challenging training phase, combined with omega 3, lecithin, and a B-complex, my thinking improved significantly, and I was surprised by the boost in my memory.
9
Fast relief
1 people found this helpful
It works. There’s no doubt in my mind that it effectively crosses the blood-brain barrier. Upon arrival, I was hungover from a night out. Moments after taking 2 capsules, my brain felt considerably better, and the ache receded. I'm very impressed. Life Extension's quality is excellent. The capsule size may be a challenge for someone with a poor swallow reflex, but they can be opened and sprinkled on food. I plan to take 300-400 mg daily now and feel more energetic and alive.
7.5
Cognitive improvements
7 people found this helpful
Works. I bought it for my child with developmental delays. This magnesium helps overcome cognitive impairment and crosses the blood-brain barrier. I noticed new words beginning to appear, and behaviour stabilising. Memory improvement is reported in reviews; I haven’t yet seen this but I feel the memorisation process is getting better.
2
Ineffective for us
7 people found this helpful
I bought two bottles, one for me and one for my dad. I took one pill before bed for better sleep and another in the morning for focus. Unfortunately, I experienced anxiety with this supplement, struggled to sleep, and found my daytime mental strength diminished. My dad, who suffers from hypertension, saw his blood pressure spike and even had nosebleeds after starting the supplement. While it appears to be a quality product, it simply did not work for us, leading to our discontinuation after two weeks. Now, I am left with over 100 pills that I won’t use.
8
We aimed to examine how bioresorbable magnesium scaffolds influence blood clotting. Using a cutting-edge stent flow chamber system, we compared the thrombogenicity of various stents, including the Magmaris magnesium scaffold and a prototype called DREAMS 3G.
Our findings indicated that the Magmaris scaffold exhibited significantly lower thrombogenicity than traditional stainless steel stents. Impressively, the DREAMS 3G prototype demonstrated even further reductions in clotting risks, suggesting it could enhance patient safety.
This study highlights the potential of magnesium-based scaffolds in improving cardiovascular treatments.
Our findings indicated that the Magmaris scaffold exhibited significantly lower thrombogenicity than traditional stainless steel stents. Impressively, the DREAMS 3G prototype demonstrated even further reductions in clotting risks, suggesting it could enhance patient safety.
This study highlights the potential of magnesium-based scaffolds in improving cardiovascular treatments.
8
MAGT1 deficiency increases thrombosis risk
We studied how a lack of magnesium transporter 1 (MAGT1) impacts blood clot formation and the risk of stroke. Using various laboratory and animal models, we observed that MAGT1 deficiency leads to enhanced platelet activity and quicker clotting. This deficiency resulted in faster artery blockage and severe brain damage during strokes. Interestingly, restoring magnesium levels or blocking certain channels helped normalize platelet behavior. Overall, we found that MAGT1's function is crucial for vascular health, indicating its deficiency could elevate risks for thrombosis and ischemic stroke.
7
We looked into how magnesium levels impact blood clotting during sepsis. In our study of ICU patients, we found that those with low magnesium (hypomagnesemia) showed a higher likelihood of having activated coagulation and suppressed fibrinolysis.
Notably, hypomagnesemia was linked to coagulopathy, specifically disseminated intravascular coagulation (DIC). This suggests that boosting magnesium levels could be a promising way to address blood clotting issues in septic patients.
Notably, hypomagnesemia was linked to coagulopathy, specifically disseminated intravascular coagulation (DIC). This suggests that boosting magnesium levels could be a promising way to address blood clotting issues in septic patients.
References
- Kim J, Kim M, Lee CS, Choi EY. Sufficient Magnesium Intake Reduces Retinal Vein Occlusion Risk: National Health and Nutrition Examination Survey Analysis. Nutrients. 2025;17. doi:10.3390/nu17071285
- Guo X, Zeng X, He Y, Zhang X, Shi W, et al. An Antibacterial, Antioxidant Adherent Sponge Constructed for Control of Arterial Bleeding Via Gallic Acid-Mediated Robust Assembly of Fibrous Clay in Collagen. ACS Appl Mater Interfaces. 2025;17:16489. doi:10.1021/acsami.4c19209
- Müller M, Ludwig L, Englert H, Riedl KA, Müller MC, et al. A novel stent flow chamber system demonstrates reduced thrombogenicity of bioresorbable magnesium scaffolds. Sci Rep. 2024;14:26691. doi:10.1038/s41598-024-77266-0
- Zhang J, Chen Z, Rao L, He Y. Coronary bioresorbable metallic stents: Advancements and future perspectives. J Cardiol. 2025;85:69. doi:10.1016/j.jjcc.2024.08.003
- Włodarczak A, Rola P, Włodarczak S, Szudrowicz M, Giniewicz K, et al. Two-Year Outcomes for Patients with Non-ST-Elevation Acute Coronary Syndrome Treated with Magmaris and Absorb Bioresorbable Scaffolds in Large-Vessel Lesions. J Pers Med. 2024;14. doi:10.3390/jpm14050540
- Galli S, Troiano S, Palloshi A, Rapetto C, Pisano F, et al. Comparison of acute versus stable coronary syndrome in patients treated with the Magmaris scaffold: Two-year results from the Magmaris Multicenter Italian Registry. Cardiovasc Revasc Med. 2023;57:53. doi:10.1016/j.carrev.2023.06.022
- Włodarczak A, Rola P, Barycki M, Furtan Ł, Łanocha M, et al. Mid-term safety and efficacy of magnesium bioresorbable vascular scaffolds - magmaris in diabetic population. 2-Years outcome in acute coronary syndrome cohort. Diab Vasc Dis Res. 2023;20:14791641231188705. doi:10.1177/14791641231188705
- Gotru SK, Mammadova-Bach E, Sogkas G, Schuhmann MK, Schmitt K, et al. MAGT1 Deficiency Dysregulates Platelet Cation Homeostasis and Accelerates Arterial Thrombosis and Ischemic Stroke in Mice. Arterioscler Thromb Vasc Biol. 2023;43:1494. doi:10.1161/ATVBAHA.122.318115
- Haude M, Wlodarczak A, van der Schaaf RJ, Torzewski J, Ferdinande B, et al. A new resorbable magnesium scaffold for de novo coronary lesions (DREAMS 3): one-year results of the BIOMAG-I first-in-human study. EuroIntervention. 2023;19:e414. doi:10.4244/EIJ-D-23-00326
- Wlodarczak A, Montorsi P, Torzewski J, Bennett J, Starmer G, et al. One- and two-year clinical outcomes of treatment with resorbable magnesium scaffolds for coronary artery disease: the prospective, international, multicentre BIOSOLVE-IV registry. EuroIntervention. 2023;19:232. doi:10.4244/EIJ-D-22-01069
- Haude M, Wlodarczak A, van der Schaaf RJ, Torzewski J, Ferdinande B, et al. Safety and performance of the third-generation drug-eluting resorbable coronary magnesium scaffold system in the treatment of subjects with de novo coronary artery lesions: 6-month results of the prospective, multicenter BIOMAG-I first-in-human study. EClinicalMedicine. 2023;59:101940. doi:10.1016/j.eclinm.2023.101940
- Pompei G, Campo G, Ruggiero R, Maffeo D, Sgura F, et al. Long-term outcomes of patients treated with sirolimus-eluting resorbable magnesium scaffolds: Insights from the SHERPA-MAGIC study. Int J Cardiol. 2023;383:1. doi:10.1016/j.ijcard.2023.04.029
- Fedele G, Castiglioni S, Maier JAM, Locatelli L. The Effects of Sirolimus and Magnesium on Primary Human Coronary Endothelial Cells: An In Vitro Study. Int J Mol Sci. 2023;24. doi:10.3390/ijms24032930
- Tonai K, Katayama S, Koyama K, Sata N, Tomioka Y, et al. Association between hypomagnesemia and coagulopathy in sepsis: a retrospective observational study. BMC Anesthesiol. 2022;22:359. doi:10.1186/s12871-022-01903-2
- Seguchi M, Aytekin A, Lenz T, Nicol P, Alvarez-Covarrubias HA, et al. Challenges of the newer generation of resorbable magnesium scaffolds: Lessons from failure mechanisms of the past generation. J Cardiol. 2023;81:179. doi:10.1016/j.jjcc.2022.09.003
- Venkatappa MM, Udagani C, Hanumegowda SM, Pramod SN, Venkataramaiah S, et al. Effect of Biofunctional Green Synthesized MgO-Nanoparticles on Oxidative-Stress-Induced Tissue Damage and Thrombosis. Molecules. 2022;27. doi:10.3390/molecules27165162
