Overview

SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.4
USERS' SCORE
Good
Based on 58 Reviews
8
Supplement Facts
Serving Size: 3 Vegetarian Capsules
Amount Per Serving
%DV
Magnesium (from 2,000 mg Magtein® magnesium L-threonate)
144 mg
34%

Top Medical Research Studies

We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.

Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.

We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
Read More
8
Magnesium aids migraine prevention
We observed that magnesium plays a notable role in migraine prevention and treatment. Specifically, magnesium is recommended for both chronic migraine management and immediate intravenous relief during acute migraine episodes. The use of magnesium appears to be linked with mild gastrointestinal side effects, indicating that it is generally well-tolerated by those who use it.

Although individual responses may vary, magnesium has shown promising results for many people managing migraines. It's essential to consider this approach alongside other treatments, as magnesium supplementation might enhance overall migraine management. For those looking for alternative or complementary options, magnesium could be a viable choice worth exploring further.
Read More
9
Magnesium significantly alleviates migraines
We explored how magnesium supplementation affects the frequency and intensity of migraine attacks. The study relied on evidence gathered from twenty-two randomized controlled trials, providing a solid foundation for our findings.

Through a detailed analysis, we found that magnesium supplementation significantly reduced migraine attacks, with a marked decrease in severity and the number of days afflicted each month. Specifically, magnesium showed a mean difference of -2.51 in attack frequency and -0.88 in severity compared to those who did not receive the supplement.

This promising outcome suggests that magnesium could be an effective option for individuals seeking migraine relief. As we delved deeper into the study, it became clear that while additional research is needed to establish long-term effects, magnesium’s immediate benefits in reducing migraines are noteworthy.
Read More

Most Useful Reviews

10
Miracle product
13 people found this helpful
For over a decade, I struggled with migraines triggered by various factors. Typically, I experienced 6-8 migraines monthly. Since using this product, I've tolerated it well and noticed a significant drop in migraines – only one compared to the usual 4-5 by now. Even when exercising, a major trigger, I've felt fine. I will continue to monitor its effects, as this truly feels miraculous.
Read More
10
Amazing results
12 people found this helpful
After suffering from chronic migraines for nine years, I finally tried magnesium oxide on my doctor's suggestion. I took three tablets at night and, astonishingly, woke up without a migraine the next day. It's been ten days of relief, and I think this pill is truly amazing.
Read More
10
Cluster headache gone
9 people found this helpful
I haven't experienced a migraine or cluster headache since taking these. Although they taste unpleasant and are quite large, they are far better than enduring endless head pain. Importantly, they don't cause the gastrointestinal issues that many magnesium supplements do, which makes me quite happy.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 21 Researches
7.4
  • All Researches
We explored how magnesium supplementation can help alleviate migraines, a condition that affects countless individuals and can be incredibly disabling. Research has shown a strong link between magnesium deficiency and various factors that contribute to migraines, such as neurological changes and inflammation.

Studies, including randomized controlled trials, indicate that magnesium can reduce the frequency and severity of migraine attacks, both in the short term and as a preventative measure. This effectiveness is thought to stem from magnesium's ability to influence nerve function and reduce stress responses in the body.

We've examined the accumulating evidence from case studies and clinical trials, and it clearly points to magnesium being a valuable option for those suffering from migraines. By addressing magnesium deficiency, we may offer a new avenue for relief and improved management of this challenging condition.
Read More
9
Magnesium significantly alleviates migraines
We explored how magnesium supplementation affects the frequency and intensity of migraine attacks. The study relied on evidence gathered from twenty-two randomized controlled trials, providing a solid foundation for our findings.

Through a detailed analysis, we found that magnesium supplementation significantly reduced migraine attacks, with a marked decrease in severity and the number of days afflicted each month. Specifically, magnesium showed a mean difference of -2.51 in attack frequency and -0.88 in severity compared to those who did not receive the supplement.

This promising outcome suggests that magnesium could be an effective option for individuals seeking migraine relief. As we delved deeper into the study, it became clear that while additional research is needed to establish long-term effects, magnesium’s immediate benefits in reducing migraines are noteworthy.
Read More
We examined how magnesium oxide (MgO), both alone and with riboflavin, helps prevent migraines in pregnant individuals. This retrospective study included 203 patients treated between 2015 and 2020, analyzing outcomes such as migraine frequency, severity, and duration.

We found that both treatment options reduced migraines significantly, with 77% of participants experiencing improvement in associated symptoms. The results indicate that magnesium oxide can be an effective option for managing migraines during pregnancy, making it a potential consideration for expectant mothers suffering from this condition.
Read More
8
Magnesium aids migraine prevention
We observed that magnesium plays a notable role in migraine prevention and treatment. Specifically, magnesium is recommended for both chronic migraine management and immediate intravenous relief during acute migraine episodes. The use of magnesium appears to be linked with mild gastrointestinal side effects, indicating that it is generally well-tolerated by those who use it.

Although individual responses may vary, magnesium has shown promising results for many people managing migraines. It's essential to consider this approach alongside other treatments, as magnesium supplementation might enhance overall migraine management. For those looking for alternative or complementary options, magnesium could be a viable choice worth exploring further.
Read More
We examined the potential role of magnesium, along with other natural ingredients, in reducing the severity and frequency of symptoms associated with vestibular migraine (VM). This observational study involved a questionnaire-based approach where we encouraged patients to consider lifestyle changes alongside an over-the-counter supplement containing magnesium and other components.

Over a three-month period, we collected data from 82 participants, focusing on symptom severity using various assessment tools. We found that there was a notable decrease in the reported severity and frequency of VM symptoms. Patients indicated improvements in their discomfort levels, with around 50% reporting better outcomes.

While magnesium was part of a combination therapy, our findings suggest that nonprescription treatments can significantly impact VM symptoms. This offers a positive outlook for individuals seeking alternative management strategies for their migraines without relying solely on prescription medications.
Read More

User Reviews

USERS' SCORE
Good
Based on 58 Reviews
8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
10
Miracle product
13 people found this helpful
For over a decade, I struggled with migraines triggered by various factors. Typically, I experienced 6-8 migraines monthly. Since using this product, I've tolerated it well and noticed a significant drop in migraines – only one compared to the usual 4-5 by now. Even when exercising, a major trigger, I've felt fine. I will continue to monitor its effects, as this truly feels miraculous.
Read More
10
Amazing results
12 people found this helpful
After suffering from chronic migraines for nine years, I finally tried magnesium oxide on my doctor's suggestion. I took three tablets at night and, astonishingly, woke up without a migraine the next day. It's been ten days of relief, and I think this pill is truly amazing.
Read More
10
Cluster headache gone
9 people found this helpful
I haven't experienced a migraine or cluster headache since taking these. Although they taste unpleasant and are quite large, they are far better than enduring endless head pain. Importantly, they don't cause the gastrointestinal issues that many magnesium supplements do, which makes me quite happy.
Read More
9
No more headaches
8 people found this helpful
This is the only magnesium that hasn't caused me headaches. The other types led to awful migraines. It aids my sleep and has greatly improved my depression and anxiety levels! Within two days, I felt more upbeat and patient throughout the day.
Read More
9
Significant improvement
4 people found this helpful
I struggled with painkillers that didn’t work until I tried Neuro-Mag L Magnesium Threonate, which has significantly improved my migraines. I sleep better now, and I highly recommend it.
Read More

Frequently Asked Questions

9
Migraine relief
8 people found this helpful
I used to suffer from migraines lasting two days. After starting this magnesium, I have not had an attack for a month. I truly hope this is my miracle cure!
7.5
Reduced frequency
1 people found this helpful
After taking one bottle, the frequency of my migraine headaches has significantly decreased.
9
Cognitive improvement
13 people found this helpful
This product is top quality. It features a patented magnesium (Magtein®), allowing it to increase magnesium levels in the brain effectively. I noticed improvements in my cognitive ability, reduced migraines, less muscle pain, and better sleep quality. Highly recommend!
7.5
Fewer migraine episodes
3 people found this helpful
I bought this supplement for my chronic migraines and have experienced fewer episodes since starting it. I also sleep better, and I appreciate that it contains no harmful ingredients. The capsule size is perfect, and the packaging is secure.
10
Migraine-free
3 people found this helpful
By taking two Neuro-mag capsules daily, I eliminated migraines that plagued me for over a decade. Now, I’m over six months migraine-free!
7.5
Calming effect
4 people found this helpful
I take magnesium along with Magnesium Glycinate for chronic migraines with visual aura and endometriosis. It provides a calming effect, effectively addressing my migraine symptoms.
9
Alleviated symptoms
1 people found this helpful
Amazing! This high-quality supplement comes in a well-sized bottle with no unpleasant taste. Magnesium has been shown to improve migraine symptoms, and I take it with meals to prevent stomach upset.
9
Improved migraine frequency
3 people found this helpful
I order Neuro-Mag, magnesium L-threonate regularly as it really improves my nervous system and memory. While taking this, I experienced fewer migraines and my panic attacks lessened.
9
Effective for migraines
1 people found this helpful
This magnesium is extremely beneficial for my migraines, anxiety, and muscle pain.
9
Magnesium significantly alleviates migraines
We explored how magnesium supplementation affects the frequency and intensity of migraine attacks. The study relied on evidence gathered from twenty-two randomized controlled trials, providing a solid foundation for our findings.

Through a detailed analysis, we found that magnesium supplementation significantly reduced migraine attacks, with a marked decrease in severity and the number of days afflicted each month. Specifically, magnesium showed a mean difference of -2.51 in attack frequency and -0.88 in severity compared to those who did not receive the supplement.

This promising outcome suggests that magnesium could be an effective option for individuals seeking migraine relief. As we delved deeper into the study, it became clear that while additional research is needed to establish long-term effects, magnesium’s immediate benefits in reducing migraines are noteworthy.
8
Magnesium aids migraine prevention
We observed that magnesium plays a notable role in migraine prevention and treatment. Specifically, magnesium is recommended for both chronic migraine management and immediate intravenous relief during acute migraine episodes. The use of magnesium appears to be linked with mild gastrointestinal side effects, indicating that it is generally well-tolerated by those who use it.

Although individual responses may vary, magnesium has shown promising results for many people managing migraines. It's essential to consider this approach alongside other treatments, as magnesium supplementation might enhance overall migraine management. For those looking for alternative or complementary options, magnesium could be a viable choice worth exploring further.
7
Magnesium linked to migraine frequency
We explored the relationship between magnesium levels and migraine in a carefully designed study. By comparing 50 migraine sufferers with an equal number of healthy individuals, we aimed to understand how magnesium, a mineral that helps regulate nerve activity, might influence migraine episodes.

Our findings revealed that patients experiencing migraines had notably lower magnesium levels both during attacks and between them compared to healthy controls. Specifically, the average magnesium level during the interictal phase was significantly lower—1.849 mg/dL for migraine patients versus 2.090 mg/dL for controls.

We also noted a concerning trend: magnesium levels decreased further during migraine attacks themselves. This suggests that lower magnesium might contribute to the headache's intensity or frequency. Furthermore, we observed an inverse relationship between magnesium levels and the frequency of migraine occurrences, indicating that as the number of attacks increased, magnesium levels tended to drop.

These results point toward magnesium potentially playing a critical role in migraine management and raise the possibility of magnesium supplementation as a therapeutic option. Understanding the connection between magnesium and migraine might open new doors for treatment strategies that could benefit many sufferers.
We observed that magnesium is often mentioned in discussions about effective treatments for migraines. This mineral plays a vital role in many bodily functions, and its potential to alleviate migraine symptoms is supported by anecdotal evidence.

Our analysis points out that while magnesium is particularly noted for its benefits, the details surrounding its standalone effectiveness in managing migraines remain unclear. It seems to work best when combined with lifestyle changes such as stress management and sleep hygiene, as well as with dietary adjustments that avoid common migraine triggers.

We understand that people looking for relief from migraines may find hope in using magnesium supplements. However, it's essential to highlight that in the broader context of migraine treatments, magnesium alone may not completely resolve the issue for everyone. So, while some individuals report improvements, it's not a one-size-fits-all solution.
7
Magnesium's potential in migraine treatment
We looked at how magnesium might affect migraines and what beneficial role it could play in treatment. Our exploration revealed that magnesium is often mentioned as a potential remedy for alleviating migraine symptoms.

Some studies indicate that magnesium could reduce the frequency and intensity of migraines. This comes from its ability to influence various processes in the body, including reducing neuroinflammation and improving blood flow.

While we noted some promising results regarding magnesium's effectiveness, it's important to highlight that the specific isolated impact of magnesium on migraine relief has not been conclusively determined. Further research may help clarify exactly how magnesium functions in migraines, ensuring that individuals can make informed choices about their treatment options.

Overall, a well-rounded approach that includes magnesium, among other lifestyle changes, could potentially enhance migraine management and improve quality of life for those affected.

References

  1. Dominguez LJ, Veronese N, Sabico S, Al-Daghri NM, Barbagallo M. Magnesium and Migraine. Nutrients. 2025;17. doi:10.3390/nu17040725
  2. Tepper SJ, Tepper K. Nutraceuticals and Headache 2024: Riboflavin, Coenzyme Q10, Feverfew, Magnesium, Melatonin, and Butterbur. Curr Pain Headache Rep. 2025;29:33. doi:10.1007/s11916-025-01358-3
  3. Hajhashemy Z, Golpour-Hamedani S, Eshaghian N, Sadeghi O, Khorvash F, et al. Practical supplements for prevention and management of migraine attacks: a narrative review. Front Nutr. 2024;11:1433390. doi:10.3389/fnut.2024.1433390
  4. Talandashti MK, Shahinfar H, Delgarm P, Jazayeri S. Effects of selected dietary supplements on migraine prophylaxis: A systematic review and dose-response meta-analysis of randomized controlled trials. Neurol Sci. 2025;46:651. doi:10.1007/s10072-024-07794-0
  5. Gazerani P, Papetti L, Dalkara T, Cook CL, Webster C, et al. The Brain, the Eating Plate, and the Gut Microbiome: Partners in Migraine Pathogenesis. Nutrients. 2024;16. doi:10.3390/nu16142222
  6. Hannigan IP, Rosengren SM, Di Tanna GL, Watson SRD, Welgampola MS. Effects of nonprescription therapies on vestibular migraine: a questionnaire-based observational study. Intern Med J. 2024;54:916. doi:10.1111/imj.16314
  7. Kurhade PI, Kodape SM, Das A, Bansod PG. Synergistic action of sumatriptan delivery and targeting magnesium deficiency using green, pH-responsive MgO nanoparticles synthesized from mahua flower extracts. Environ Sci Pollut Res Int. 2023. doi:10.1007/s11356-023-30648-9
  8. Umemoto KK, Tawk K, Mazhari N, Abouzari M, Djalilian HR. Management of Migraine-Associated Vestibulocochlear Disorders. Audiol Res. 2023;13:528. doi:10.3390/audiolres13040047
  9. Gaul C, Zaranek L, Goßrau G. [Complementary and supplementary procedures in the treatment of headache]. Schmerz. 2023;37:448. doi:10.1007/s00482-023-00738-1
  10. Shenoy NN, Gheewala GK, Kedambadi R, Pai S, Zulfikli KM, et al. Can Serum Magnesium Level and Visual Evoked Potentials (P100) be a Predictive in Migraineurs?: Evidence Based Study. Neurol India. 2023;71:463. doi:10.4103/0028-3886.378668
  11. Frank M, Abouzari M, Djalilian HR. Meniere's disease is a manifestation of migraine. Curr Opin Otolaryngol Head Neck Surg. 2023;31:313. doi:10.1097/MOO.0000000000000908
  12. Pawar V, Ashraf H, Dorsala S, Mary P, Hameed N, et al. Motorist's Vestibular Disorientation Syndrome (MVDS)-Proposed Diagnostic Criteria. J Pers Med. 2023;13. doi:10.3390/jpm13050732
  13. Hoshino MT, Bochio MG, Spagnol Bonache J, Ludwig L, Leandro de Campos M, et al. Plasma and erythrocyte magnesium levels: from validation of the method to analysis in volunteers diagnosed to migraine. Magnes Res. 2022;35:51. doi:10.1684/mrh.2022.0502
  14. Mahajan R, Anand KS, Mahajan RK, Garg J, Juneja A. Serum Magnesium Levels During the Ictal and Interictal Phase in Patients of Migraine: A Prospective Observational Study. Neurol India. 2022;70:1852. doi:10.4103/0028-3886.359247
  15. Bhurat R, Premkumar S, Manokaran RK. Serum Magnesium Levels in Children With and Without Migraine: A Cross-Sectional Study. Indian Pediatr. 2022;59:623.
  16. Mazza GR, Solorio C, Stek AM, Kalayjian LA, Wilson ML, et al. Assessing the efficacy of magnesium oxide and riboflavin as preventative treatment of migraines in pregnancy. Arch Gynecol Obstet. 2023;308:1749. doi:10.1007/s00404-022-06872-y
  17. Ariyanfar S, Razeghi Jahromi S, Togha M, Ghorbani Z. Review on Headache Related to Dietary Supplements. Curr Pain Headache Rep. 2022;26:193. doi:10.1007/s11916-022-01019-9
  18. Guerrero-Toro C, Koroleva K, Ermakova E, Gafurov O, Abushik P, et al. Testing the Role of Glutamate NMDA Receptors in Peripheral Trigeminal Nociception Implicated in Migraine Pain. Int J Mol Sci. 2022;23. doi:10.3390/ijms23031529
  19. Matin H, Taghian F, Chitsaz A. Artificial intelligence analysis to explore synchronize exercise, cobalamin, and magnesium as new actors to therapeutic of migraine symptoms: a randomized, placebo-controlled trial. Neurol Sci. 2022;43:4413. doi:10.1007/s10072-021-05843-6
  20. Karim MR, Bhattacharjee M, Islam MS, Banerjee S, Hossain S, et al. Relation between Serum Magnesium Level and Migraine. Mymensingh Med J. 2021;30:301.
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