' 
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.7
USERS' SCORE
Good
Based on 16 Reviews
8.6
Supplement Facts
Serving Size: 2 Enteric Coated Softgels
Amount Per Serving
%DV
Calories
25
Total Fat
2.5 g
4%†
Cholesterol
<5 mg
2%†
Pure+™ Wild Fish Oil ConcentrateYielding: EPA (eicosapentaenoic acid)DHA (docosahexaenoic acid)
2,000 mg700 mg500 mg
******
Polyphen-Oil™ Olive extract (fruit and leaf)[providing 19.5 mg polyphenols, 5.2 mg hydroxytyrosol/tyrosol, 4.4 mg verbascoside/oleuropein]
300 mg
**
Sesame seed lignan extract
10 mg
**
Top Medical Research Studies
9
Omega-3 reduces heart disease risk
Association of Plasma Omega-3 Levels With Incident Heart Failure and Related Mortalities.
High relevance to heart disease
We examined the relationship between plasma omega-3 levels and heart failure (HF), focusing on how this affects mortality in patients with existing HF. Our analysis of the UK Biobank, which included nearly 272,000 participants without HF, showed that higher omega-3 levels were linked to a 21% lower risk of developing HF over nearly 14 years.
For those already diagnosed with HF, higher omega-3 levels significantly reduced the risk of all-cause and cardiovascular mortality by around 50%. These findings suggest that boosting omega-3 intake could be beneficial for heart health.
For those already diagnosed with HF, higher omega-3 levels significantly reduced the risk of all-cause and cardiovascular mortality by around 50%. These findings suggest that boosting omega-3 intake could be beneficial for heart health.
Read More
8
EPA lowers heart rhythm problems
Eicosapentaenoic acid prevents atrial electrocardiographic impairments and atrial fibrillation in high fat diet mice.
Study shows solid relevance
We investigated how eicosapentaenoic acid (EPA) affects heart rhythm, particularly in the context of high-fat diets. In our study, mice were divided into two groups: one received a high-fat diet, while the other’s diet was supplemented with EPA for eight weeks.
We observed that the mice on a high-fat diet experienced severe heart rhythm issues, such as bradycardia and atrial fibrillation (AF). In contrast, the EPA group showed significantly less AF and better heart function. These results suggest that including EPA in the diet could be a promising strategy to support heart health and reduce the risk of arrhythmias.
We observed that the mice on a high-fat diet experienced severe heart rhythm issues, such as bradycardia and atrial fibrillation (AF). In contrast, the EPA group showed significantly less AF and better heart function. These results suggest that including EPA in the diet could be a promising strategy to support heart health and reduce the risk of arrhythmias.
Read More
9
High-dose omega-3 improves heart function
The Optimal Dosage and Duration of ω-3 PUFA Supplementation in Heart Failure Management: Evidence from a Network Meta-Analysis.
Effective treatment mechanism insight
We explored how omega-3 polyunsaturated fatty acids (PUFAs) can help manage heart failure by analyzing 14 randomized controlled trials involving over 9,000 participants.
Our findings revealed that high doses—between 2000 and 4000 mg daily—taken for at least a year, remarkably improved heart function.
However, lower doses or shorter treatment periods didn’t show the same benefits. Notably, there were no increased risks of adverse events or dropout rates in those taking omega-3 compared to control groups.
Our findings revealed that high doses—between 2000 and 4000 mg daily—taken for at least a year, remarkably improved heart function.
However, lower doses or shorter treatment periods didn’t show the same benefits. Notably, there were no increased risks of adverse events or dropout rates in those taking omega-3 compared to control groups.
Read More
Most Useful Reviews
9.5
Improved heart function
An excellent supplement for bolstering heart health, enhancing cognitive function, and reducing inflammation. I’m pleased with the outcomes and will continue its use. I recommend it for improving cardiovascular health; I’ve noticed an enhancement in heart function and an overall feeling of alertness, alongside better concentration. After a few weeks, my heart function improved, and I experienced less fatigue post-exercise.
Read More
9.5
Supports heart health
The quality of this omega is top-notch, made from fish caught in natural waters, with purity certificates available. It’s enriched with polyphenols from olive leaves and sesame extract, providing a valuable supplement for the heart and circulation. Given the price per serving, it’s competitive with basic omega options. I’ll update my review after a month of use.
Read More
9
Vital compounds identified
This product is wonderful; Omega-3 is essential, especially the compounds ALA and DHA, which are necessary for heart and blood vessel protection. Their total should be between 1 gram and 2 grams.
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.7
- All Researches
9
Omega-3 fatty acids show safety
EPA and DHA acylcarnitines are less cardiotoxic than are saturated and monounsaturated long-chain acylcarnitines.
High relevance to heart health
We analyzed the impact of different fatty acid-derived acylcarnitines on heart health. The study found that saturated and monounsaturated acylcarnitines, especially trans-elaidoylcarnitine, significantly impaired heart function and mitochondrial activity, leading to cardiotoxicity.
In contrast, omega-3-derived acylcarnitines, like eicosapentaenoylcarnitine and docosahexaenoylcarnitine, were found to be safe, having little to no negative effect on heart function and cell viability. Overall, this research suggests that omega-3 fatty acids may be a safer option for those facing cardiac challenges.
In contrast, omega-3-derived acylcarnitines, like eicosapentaenoylcarnitine and docosahexaenoylcarnitine, were found to be safe, having little to no negative effect on heart function and cell viability. Overall, this research suggests that omega-3 fatty acids may be a safer option for those facing cardiac challenges.
Read More
9
High-dose omega-3 improves heart function
The Optimal Dosage and Duration of ω-3 PUFA Supplementation in Heart Failure Management: Evidence from a Network Meta-Analysis.
Effective treatment mechanism insight
We explored how omega-3 polyunsaturated fatty acids (PUFAs) can help manage heart failure by analyzing 14 randomized controlled trials involving over 9,000 participants.
Our findings revealed that high doses—between 2000 and 4000 mg daily—taken for at least a year, remarkably improved heart function.
However, lower doses or shorter treatment periods didn’t show the same benefits. Notably, there were no increased risks of adverse events or dropout rates in those taking omega-3 compared to control groups.
Our findings revealed that high doses—between 2000 and 4000 mg daily—taken for at least a year, remarkably improved heart function.
However, lower doses or shorter treatment periods didn’t show the same benefits. Notably, there were no increased risks of adverse events or dropout rates in those taking omega-3 compared to control groups.
Read More
9
Omega-3 reduces heart disease risk
Association of Plasma Omega-3 Levels With Incident Heart Failure and Related Mortalities.
High relevance to heart disease
We examined the relationship between plasma omega-3 levels and heart failure (HF), focusing on how this affects mortality in patients with existing HF. Our analysis of the UK Biobank, which included nearly 272,000 participants without HF, showed that higher omega-3 levels were linked to a 21% lower risk of developing HF over nearly 14 years.
For those already diagnosed with HF, higher omega-3 levels significantly reduced the risk of all-cause and cardiovascular mortality by around 50%. These findings suggest that boosting omega-3 intake could be beneficial for heart health.
For those already diagnosed with HF, higher omega-3 levels significantly reduced the risk of all-cause and cardiovascular mortality by around 50%. These findings suggest that boosting omega-3 intake could be beneficial for heart health.
Read More
9
Omega-3 benefits African Americans’ heart health
Optimal Pair Matching Combined with Machine Learning Predicts a Significant Reduction in Myocardial Infarction Risk in African Americans Following Omega-3 Fatty Acid Supplementation.
High relevance due to disparities
We observed that the role of omega-3 fatty acids in heart health showed promising results specifically for African Americans. By comparing matched groups from the VITAL trial, we found that omega-3 supplementation significantly reduced the risk of myocardial infarction in African Americans, while no such benefit was seen in non-Hispanic whites.
This suggests that genetic or lifestyle factors may influence the effectiveness of these supplements. Our findings highlight the importance of further research to better understand how race affects responses to omega-3 supplementation.
This suggests that genetic or lifestyle factors may influence the effectiveness of these supplements. Our findings highlight the importance of further research to better understand how race affects responses to omega-3 supplementation.
Read More
8
EPA lowers heart rhythm problems
Eicosapentaenoic acid prevents atrial electrocardiographic impairments and atrial fibrillation in high fat diet mice.
Study shows solid relevance
We investigated how eicosapentaenoic acid (EPA) affects heart rhythm, particularly in the context of high-fat diets. In our study, mice were divided into two groups: one received a high-fat diet, while the other’s diet was supplemented with EPA for eight weeks.
We observed that the mice on a high-fat diet experienced severe heart rhythm issues, such as bradycardia and atrial fibrillation (AF). In contrast, the EPA group showed significantly less AF and better heart function. These results suggest that including EPA in the diet could be a promising strategy to support heart health and reduce the risk of arrhythmias.
We observed that the mice on a high-fat diet experienced severe heart rhythm issues, such as bradycardia and atrial fibrillation (AF). In contrast, the EPA group showed significantly less AF and better heart function. These results suggest that including EPA in the diet could be a promising strategy to support heart health and reduce the risk of arrhythmias.
Read More
User Reviews
USERS' SCORE
Good
Based on 16 Reviews
8.6
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Improved heart function
An excellent supplement for bolstering heart health, enhancing cognitive function, and reducing inflammation. I’m pleased with the outcomes and will continue its use. I recommend it for improving cardiovascular health; I’ve noticed an enhancement in heart function and an overall feeling of alertness, alongside better concentration. After a few weeks, my heart function improved, and I experienced less fatigue post-exercise.
Read More
9.5
Supports heart health
The quality of this omega is top-notch, made from fish caught in natural waters, with purity certificates available. It’s enriched with polyphenols from olive leaves and sesame extract, providing a valuable supplement for the heart and circulation. Given the price per serving, it’s competitive with basic omega options. I’ll update my review after a month of use.
Read More
9
Vital compounds identified
This product is wonderful; Omega-3 is essential, especially the compounds ALA and DHA, which are necessary for heart and blood vessel protection. Their total should be between 1 gram and 2 grams.
8.8
Decreased palpitations
I feel that my heart palpitations have lessened significantly. Indefinite complaints and headaches have also subsided. This may not be the sole reason, but given that fish is pricey and cooking is laborious, taking supplements is far more convenient for me.
8.8
High-quality fish oil
After a lengthy search for high-quality fish oil with substantial levels of EPA and DHA, I chose Life Extension, Super Omega-3. After months of use, I’ve found it significantly beneficial. The high Omega-3 concentration is crucial for heart health, and the capsules have no fishy aftertaste. I noticed better concentration, reduced fatigue, and even improved skin. Although the capsules are large and the price is higher, the quality makes it worth it.
Read More
