Last update
5/13/2025
Research Authors

Overview

SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
USERS' SCORE
Medium or Average
Based on 15 Reviews
6.8
Supplement Facts
Serving Size: 1 Vegetarian Capsule
Amount Per Serving
%DV
Zinc (as OptiZinc® zinc monomethionine, zinc citrate)
50 mg
455%

Top Medical Research Studies

We investigated how zinc affects heartburn through the case of a 76-year-old Japanese man who experienced significant discomfort after undergoing a total gastrectomy. For two weeks, he suffered from a sore throat, heartburn, and difficulty swallowing. Endoscopy revealed deep, craterlike ulcers in his esophagus, but tests for viral infections were negative.

After initial treatment, his symptoms returned, prompting further investigation. Eventually, we found that his serum zinc level was low at 38 µg/dL, which led to a diagnosis of zinc deficiency. Following oral zinc supplementation, the patient reported relief from his symptoms and a noticeable improvement in the esophageal ulcers observed during a follow-up endoscopy.

Over the five years since his treatment, the patient has continued to take zinc supplements and has not faced similar issues again. This case suggests that zinc can play a crucial role in treating heartburn issues related to ulcers, especially in those with a deficiency.
Read More

Most Useful Reviews

9
Helps calm heartburn
13 people found this helpful
I believe I am prone to mouth ulcers if I run out of this supplement. I take zinc and B6 to prevent ulcers, particularly on my tongue, as they can indicate a deficiency in zinc. Supplementing with zinc helps heal my stomach when it feels hot, alleviating heartburn.
Read More
9
Strengthens immunity
6 people found this helpful
This cycle works well; my hair has stopped falling out, and the ingredients did not cause allergies. I noticed effects after a week, and it did not cause heartburn. Taking it at night improves my immunity and the capsules are convenient.
Read More
9
Restores energy
Zinc is an essential trace element that helps fight infections and regulates blood sugar. I experienced fatigue and poor sleep due to a deficiency. After starting zinc, my strength returned, sleep improved, and I no longer suffer from heartburn or allergies. I'm moving quickly and eating normally now.
Read More

Medical Researches

SCIENTIFIC SCORE
Likely Very Effective
Based on 1 Research
9
  • All Researches
We investigated how zinc affects heartburn through the case of a 76-year-old Japanese man who experienced significant discomfort after undergoing a total gastrectomy. For two weeks, he suffered from a sore throat, heartburn, and difficulty swallowing. Endoscopy revealed deep, craterlike ulcers in his esophagus, but tests for viral infections were negative.

After initial treatment, his symptoms returned, prompting further investigation. Eventually, we found that his serum zinc level was low at 38 µg/dL, which led to a diagnosis of zinc deficiency. Following oral zinc supplementation, the patient reported relief from his symptoms and a noticeable improvement in the esophageal ulcers observed during a follow-up endoscopy.

Over the five years since his treatment, the patient has continued to take zinc supplements and has not faced similar issues again. This case suggests that zinc can play a crucial role in treating heartburn issues related to ulcers, especially in those with a deficiency.
Read More

User Reviews

USERS' SCORE
Medium or Average
Based on 15 Reviews
6.8
  • All Reviews
  • Positive Reviews
  • Negative Reviews
9
Helps calm heartburn
13 people found this helpful
I believe I am prone to mouth ulcers if I run out of this supplement. I take zinc and B6 to prevent ulcers, particularly on my tongue, as they can indicate a deficiency in zinc. Supplementing with zinc helps heal my stomach when it feels hot, alleviating heartburn.
Read More
9
Strengthens immunity
6 people found this helpful
This cycle works well; my hair has stopped falling out, and the ingredients did not cause allergies. I noticed effects after a week, and it did not cause heartburn. Taking it at night improves my immunity and the capsules are convenient.
Read More
9
Restores energy
Zinc is an essential trace element that helps fight infections and regulates blood sugar. I experienced fatigue and poor sleep due to a deficiency. After starting zinc, my strength returned, sleep improved, and I no longer suffer from heartburn or allergies. I'm moving quickly and eating normally now.
Read More
9
Improves skin problems
Excellent capsules with convenient dosage. I prefer these over regular pills. Zinc is especially beneficial for those consuming lots of sugar, which depletes zinc levels, causing symptoms like white spots on nails and skin issues. The supplement also helps with heartburn and boosts immunity during stress.
Read More
9
High dosage convenience
I appreciate the high dosage of zinc, allowing me to take just one capsule daily. It has not caused heartburn like other preparations, and I feel it effectively suppresses inflammation in my body.
Read More

Frequently Asked Questions

9
Strengthens immunity
6 people found this helpful
This cycle works well; my hair has stopped falling out, and the ingredients did not cause allergies. I noticed effects after a week, and it did not cause heartburn. Taking it at night improves my immunity and the capsules are convenient.
9
Restores energy
Zinc is an essential trace element that helps fight infections and regulates blood sugar. I experienced fatigue and poor sleep due to a deficiency. After starting zinc, my strength returned, sleep improved, and I no longer suffer from heartburn or allergies. I'm moving quickly and eating normally now.
5
Heartburn after meals
Taking it on an empty stomach caused me heartburn. However, it was fine after a meal. I believe it is effective.
0
Family heartburn reactions
My family and I experienced heartburn after taking these capsules, from my 8-year-old son to my 70-year-old mother. I'm uncertain if everyone will have a similar reaction.
9
High dosage convenience
I appreciate the high dosage of zinc, allowing me to take just one capsule daily. It has not caused heartburn like other preparations, and I feel it effectively suppresses inflammation in my body.
1
Discomfort present
Good zinc that aided me during a cold; however, it caused heartburn, prompting me to switch to another brand.
9
Helps calm heartburn
13 people found this helpful
I believe I am prone to mouth ulcers if I run out of this supplement. I take zinc and B6 to prevent ulcers, particularly on my tongue, as they can indicate a deficiency in zinc. Supplementing with zinc helps heal my stomach when it feels hot, alleviating heartburn.
We investigated how zinc affects heartburn through the case of a 76-year-old Japanese man who experienced significant discomfort after undergoing a total gastrectomy. For two weeks, he suffered from a sore throat, heartburn, and difficulty swallowing. Endoscopy revealed deep, craterlike ulcers in his esophagus, but tests for viral infections were negative.

After initial treatment, his symptoms returned, prompting further investigation. Eventually, we found that his serum zinc level was low at 38 µg/dL, which led to a diagnosis of zinc deficiency. Following oral zinc supplementation, the patient reported relief from his symptoms and a noticeable improvement in the esophageal ulcers observed during a follow-up endoscopy.

Over the five years since his treatment, the patient has continued to take zinc supplements and has not faced similar issues again. This case suggests that zinc can play a crucial role in treating heartburn issues related to ulcers, especially in those with a deficiency.

References

  1. Hayashi A, Taki Y, Arai K, Sato S, Higashizono K, et al. Esophageal ulcer related to zinc deficiency following a total gastrectomy. Nutrition. 2023;110:111999. 10.1016/j.nut.2023.111999
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