' 
SCIENTIFIC SCORE
Possibly Effective
Based on 29 Researches
7.9
USERS' SCORE
Good
Based on 16 Reviews
8.7
Supplement Facts
Serving Size: 1 Vegetarian Capsule
Amount Per Serving
%DV
Vitamin E (as D-alpha tocopheryl succinate)
20.1 mg
134%
Selenium (as Se-Methyl L-Selenocysteine, L-selenomethionine (yeast-free), sodium selenite)
200 mcg
364%
Top Medical Research Studies
9.5
Selenium nanoparticles reduce liver toxicity
Chitosan-encapsulated selenium nanoparticles alleviate CCl induced hepatotoxicity through synergistically modulating NF-κB and Nrf2 signaling pathways and regulating Bcl-2 and Caspase-3 expression: A comprehensive study with multiple regression analysis.
High relevance to liver toxicity
We investigated how selenium nanoparticles (Se-NPs) and chitosan-encapsulated selenium nanoparticles (Se-CS-NPs) can mitigate liver toxicity induced by carbon tetrachloride (CCl) in rats. In our study, eighty rats were divided into eight groups, including placebo and control.
The findings indicated that both forms of selenium helped in reducing liver damage by influencing key biological markers. Notably, while selenium was effective, encapsulating it with chitosan did not provide additional benefits. Overall, these nanoparticles could be a valuable treatment option against liver toxicity.
The findings indicated that both forms of selenium helped in reducing liver damage by influencing key biological markers. Notably, while selenium was effective, encapsulating it with chitosan did not provide additional benefits. Overall, these nanoparticles could be a valuable treatment option against liver toxicity.
Read More
9
Vitamin E shows promise for MASH
Vitamin E (300 mg) in the treatment of MASH: A multi-center, randomized, double-blind, placebo-controlled study.
High relevance to liver disease
We investigated the effects of a daily dose of 300 mg vitamin E for treating metabolic dysfunction-associated steatohepatitis (MASH). In our study, 124 non-diabetic individuals were randomly assigned to either vitamin E or a placebo.
The results showed that 29.3% of those on vitamin E had improvements in liver histology, compared to just 14.1% in the placebo group. While we saw significant benefits in liver conditions like steatosis and inflammation, 12 serious adverse events were reported, although they weren’t linked to the treatment.
Overall, our findings indicate that vitamin E may offer meaningful improvements in liver health for those with MASH.
The results showed that 29.3% of those on vitamin E had improvements in liver histology, compared to just 14.1% in the placebo group. While we saw significant benefits in liver conditions like steatosis and inflammation, 12 serious adverse events were reported, although they weren’t linked to the treatment.
Overall, our findings indicate that vitamin E may offer meaningful improvements in liver health for those with MASH.
Read More
9
Vitamin E improves liver markers
Vitamin E improves serum markers and histology in adults with metabolic dysfunction-associated steatotic liver disease: Systematic review and meta-analysis.
Relevant for liver disease research
We analyzed multiple clinical trials to understand how vitamin E impacts liver disease, specifically metabolic dysfunction-associated steatotic liver disease (MASLD).
Our findings reveal that vitamin E significantly improves key liver markers like alanine aminotransferase (ALT) and aspartate aminotransferase (AST), suggesting it may help reduce liver inflammation.
Additionally, vitamin E enhances liver histology by decreasing fat accumulation and inflammation. However, it does not appear to affect liver fibrosis.
Overall, vitamin E could be a valuable option for managing liver health in MASLD patients.
Our findings reveal that vitamin E significantly improves key liver markers like alanine aminotransferase (ALT) and aspartate aminotransferase (AST), suggesting it may help reduce liver inflammation.
Additionally, vitamin E enhances liver histology by decreasing fat accumulation and inflammation. However, it does not appear to affect liver fibrosis.
Overall, vitamin E could be a valuable option for managing liver health in MASLD patients.
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Most Useful Reviews
9.5
Supports eye health
I use selenium for treating endocrine ophthalmopathy, and currently, in Russia, there are no pure selenium products available. This selenium combines three forms, and I alternate it with another brand. Endocrinologists recommend its use for mild cases. After four months, I can attest to its effectiveness; my symptoms have significantly improved, including the regression of eye issues related to thyroid disease.
Read More
9.5
Miraculous health improvement
This is the one to get. I'm so glad I bought this. I realised the symptoms I experienced were due to an unsupported liver that was becoming overwhelmed by daily toxins. I had a serious issue for over six months. I was advised that selenium would help support my liver and enable it to detoxify, and after two weeks of taking this, the major symptoms completely disappeared. It feels like a miracle. Many people may not experience such dramatic health improvements, and I couldn't be happier.
Read More
9
Important nutritional supplement
I took selenium for its wonderful components and its benefits in enhancing liver function. Now, on the twenty-fifth day, I find it an important nutritional supplement with no symptoms and no taste. We take one pill a day with meals. The package lasts three months. I believe it benefits hormones in women and male fertility. I hope this information helps you. Good luck to everyone!
Read More
Medical Researches
SCIENTIFIC SCORE
Possibly Effective
Based on 29 Researches
7.9
- All Researches
9.5
Selenium nanoparticles reduce liver toxicity
Chitosan-encapsulated selenium nanoparticles alleviate CCl induced hepatotoxicity through synergistically modulating NF-κB and Nrf2 signaling pathways and regulating Bcl-2 and Caspase-3 expression: A comprehensive study with multiple regression analysis.
High relevance to liver toxicity
We investigated how selenium nanoparticles (Se-NPs) and chitosan-encapsulated selenium nanoparticles (Se-CS-NPs) can mitigate liver toxicity induced by carbon tetrachloride (CCl) in rats. In our study, eighty rats were divided into eight groups, including placebo and control.
The findings indicated that both forms of selenium helped in reducing liver damage by influencing key biological markers. Notably, while selenium was effective, encapsulating it with chitosan did not provide additional benefits. Overall, these nanoparticles could be a valuable treatment option against liver toxicity.
The findings indicated that both forms of selenium helped in reducing liver damage by influencing key biological markers. Notably, while selenium was effective, encapsulating it with chitosan did not provide additional benefits. Overall, these nanoparticles could be a valuable treatment option against liver toxicity.
Read More
9
Selenium and CoQ improve liver health
Coenzyme Q and Selenium Co-Supplementation Alleviate Methionine Choline-Deficient Diet-Induced Metabolic Dysfunction-Associated Steatohepatitis in Mice.
High relevance for liver treatment
We aimed to investigate the role of selenium and coenzyme Q in addressing liver damage caused by a methionine choline-deficient diet in mice. Over four weeks, mice receiving the combination treatment showed significant reductions in liver inflammation, fibrosis, and oxidative stress.
The results suggested that this combined supplementation might hold therapeutic potential against metabolic dysfunction-associated liver injury. While our findings are promising, they are based on an animal model, and further research is necessary to explore their implications for human liver disease.
The results suggested that this combined supplementation might hold therapeutic potential against metabolic dysfunction-associated liver injury. While our findings are promising, they are based on an animal model, and further research is necessary to explore their implications for human liver disease.
Read More
9
Selenium enhances liver health
Glutathione and Selenium Supplementation Attenuates Liver Injury in Diethylnitrosamine-Induced Hepatocarcinogenic Mice by Enhancing Glutathione-Related Antioxidant Capacities.
High relevance to liver research
We set out to investigate if selenium, along with glutathione, can help reduce liver injury caused by a cancer-inducing substance in mice. Over 20 weeks, we divided male mice into different groups, some receiving selenium and others just glutathione, while monitoring their liver function.
Our findings revealed that both supplements significantly improved liver conditions and antioxidant levels. Interestingly, adding selenium to glutathione treatment worked even better, enhancing the liver’s ability to handle oxidative stress. Overall, selenium appears to be a promising ally in supporting liver health and reducing injury.
Our findings revealed that both supplements significantly improved liver conditions and antioxidant levels. Interestingly, adding selenium to glutathione treatment worked even better, enhancing the liver’s ability to handle oxidative stress. Overall, selenium appears to be a promising ally in supporting liver health and reducing injury.
Read More
9
Selenium aids in liver protection
Selenium Attenuates Ethanol-induced Hepatocellular Injury by Regulating Ferroptosis and Apoptosis.
Significant findings on liver health
We explored the potential of selenium in addressing liver damage caused by alcohol. The study employed both in vitro and in vivo methods to assess how selenium affects liver cells exposed to ethanol.
Our findings indicated that selenium improved cell viability, reduced oxidative stress markers, and altered certain protein expressions related to cell death. In particular, selenomethionine showed a notable impact in protecting liver cells.
Overall, selenium appears promising for alleviating ethanol-induced liver injury by regulating important cellular processes. However, results suggest that further research is needed to fully understand its effectiveness.
Our findings indicated that selenium improved cell viability, reduced oxidative stress markers, and altered certain protein expressions related to cell death. In particular, selenomethionine showed a notable impact in protecting liver cells.
Overall, selenium appears promising for alleviating ethanol-induced liver injury by regulating important cellular processes. However, results suggest that further research is needed to fully understand its effectiveness.
Read More
9
Vitamin E shows promise for MASH
Vitamin E (300 mg) in the treatment of MASH: A multi-center, randomized, double-blind, placebo-controlled study.
High relevance to liver disease
We investigated the effects of a daily dose of 300 mg vitamin E for treating metabolic dysfunction-associated steatohepatitis (MASH). In our study, 124 non-diabetic individuals were randomly assigned to either vitamin E or a placebo.
The results showed that 29.3% of those on vitamin E had improvements in liver histology, compared to just 14.1% in the placebo group. While we saw significant benefits in liver conditions like steatosis and inflammation, 12 serious adverse events were reported, although they weren’t linked to the treatment.
Overall, our findings indicate that vitamin E may offer meaningful improvements in liver health for those with MASH.
The results showed that 29.3% of those on vitamin E had improvements in liver histology, compared to just 14.1% in the placebo group. While we saw significant benefits in liver conditions like steatosis and inflammation, 12 serious adverse events were reported, although they weren’t linked to the treatment.
Overall, our findings indicate that vitamin E may offer meaningful improvements in liver health for those with MASH.
Read More
User Reviews
USERS' SCORE
Good
Based on 16 Reviews
8.7
- All Reviews
- Positive Reviews
- Negative Reviews
9.5
Supports eye health
I use selenium for treating endocrine ophthalmopathy, and currently, in Russia, there are no pure selenium products available. This selenium combines three forms, and I alternate it with another brand. Endocrinologists recommend its use for mild cases. After four months, I can attest to its effectiveness; my symptoms have significantly improved, including the regression of eye issues related to thyroid disease.
Read More
9.5
Miraculous health improvement
This is the one to get. I'm so glad I bought this. I realised the symptoms I experienced were due to an unsupported liver that was becoming overwhelmed by daily toxins. I had a serious issue for over six months. I was advised that selenium would help support my liver and enable it to detoxify, and after two weeks of taking this, the major symptoms completely disappeared. It feels like a miracle. Many people may not experience such dramatic health improvements, and I couldn't be happier.
Read More
9
Important nutritional supplement
I took selenium for its wonderful components and its benefits in enhancing liver function. Now, on the twenty-fifth day, I find it an important nutritional supplement with no symptoms and no taste. We take one pill a day with meals. The package lasts three months. I believe it benefits hormones in women and male fertility. I hope this information helps you. Good luck to everyone!
Read More
9.5
Reduces thyroid issues
I've taken compound selenium for many years, leading to the disappearance of my thyroid nodules within a year. I've recommended it to friends, one of whom, despite having multiple intestinal polyps and an unremarkable colonoscopy, found success with it. The supplement also has protective benefits for the liver and heart. My entire family intends to continue using it.
Read More
9.5
Effective for thyroid
I found selenium to be extremely effective for patients with Hashimoto's thyroid disease. It has made a noticeable difference in health.
