Natrol Biotin

Biotin's potential in acne treatment

Possibly Effective

Based on 5 Researches

Piraccini BM, Berardesca E, Fabbrocini G, Micali G, Tosti A. Biotin: overview of the treatment of diseases of cutaneous appendages and of hyperseborrhea. G Ital Dermatol Venereol. 2019;154:557. doi:10.23736/S0392-0488.19.06434-4

We explored the effectiveness of biotin as a treatment for acne, focusing on its potential benefits for those experiencing skin issues linked to biotin deficiency. Biotin is a vitamin that, when levels are low, can contribute to hair loss and skin disorders like seborrheic dermatitis.

In our overview, we noted that while biotin may help improve hair loss, its impact on acne treatment shows promise primarily when combined with other therapies, particularly topical retinoids. These treatments address not just acne but also flaking and irritation commonly associated with skin conditions.

Overall, we found that biotin's role in managing acne is intriguing, especially given its excellent tolerability and safety, even at high doses. However, we emphasize that biotin should be taken under medical supervision following a proper diagnosis.

Improved skin tone

Most Useful Review

105 people found this helpful

I decided to continue taking this product after my second purchase. I have struggled with rough skin and acne for about 10 years, but I think this supplement, along with other vitamins, has been effective. After taking one pill daily for two months, my skin tone improved and I have no new acne. It worked for me, so I will keep taking it.

Updated: Mar 2026

Chemotherapy details

11 people found this helpful

Great! I've been using this after chemotherapy, and it has made my hair grow faster. I have a lot of baby hair already. It has been really effective for me, which is why I keep repurchasing it. However, my hair remains brittle, but I think that's due to COVID.

WOW! I have anaemia and don't eat healthily, resulting in significant hair loss. After two months of taking biotin with other supplements, I can see a marked difference. I also appreciate the price!

Anemia details

Blurred Vision details

Improved vision noted

Suitable for my body. My condition is improving daily, with better skin, hair, and nails. I also experience enhanced hearing and vision. Thank you for such brilliant products—I am very pleased with them.

Bruise details

Enhanced eyelash growth

It was effective. There was a bruise on his forehead, and his eyebrows were plentiful, but they became rich. My eyelashes have grown longer.

Seborrheic dermatitis relief

Cardiovascular Disease details

1 people found this helpful

I've had seborrheic dermatitis on my scalp for years, but after a month of taking biotin and krill oil, the itching has reduced dramatically. I intend to continue this regimen as I’ve experienced such positive results. I believe in the quality of iHerb's supplements and feel reassured using them.

90 people found this helpful

Depression details

I've taken this vitamin for several months now, and it has been excellent. I take it daily to maintain my health, and I've seen improvements not only in my immunity but also in my mood, which is fantastic given my battle with depression.

With a deficiency of vitamin D3 in women, the risk of various genitourinary diseases increases. During pregnancy, vitamin D3 aids calcium-phosphorus metabolism for a healthy gestation. Following menopause, the risk of osteoporosis significantly rises due to low estrogen. I took biotin for my hair, nails, and skin, and after one jar, I noticed a marked improvement.

Osteoporosis details

These vitamins truly work! My anxiety has diminished, and I’m sleeping better. However, taking four capsules feels excessive. I recommend dividing the dose into two in the morning and two before bed. They are expensive, but effective for stress relief without causing drowsiness!

Anxiety details

Products containing biotin are definitely effective. I started taking it 2-3 years after menopause due to hair loss and nail issues, and it works well as I consistently take it. My nails are healthy and growing long quickly, so I'm busy taking care of them.

Menopause details

9 people found this helpful

Back Pain details

This product effectively saved me from postpartum hair loss! Three months after giving birth, I experienced significant hair loss, but after taking this supplement daily, I noticed my hair started to grow back, and daily shedding has nearly stopped. My hair is returning quickly, and I believe it has shortened the duration of my hair loss. Highly recommended for mothers!

Blood Clot details

Increased hair growth

6 people found this helpful

Since taking this biotin supplement, my hair growth has been remarkable, and my nails are growing much faster. Despite a busy life and only averaging five hours of sleep, I've felt improvements in my overall health. I've noticed less unwanted hair growth, and I'm experiencing noticeable changes in my hair and nails in just a month.

Diabetes details

Peptide hydrogel boosts islet transplantation

Possibly Effective

Based on 3 Researches

Cai X, Zhang M, Zou J, Wang L, Zhan Y, et al. A novel self-assembling peptide nanofiber hydrogel with glucagon-like peptide-1 functionality enhances islet survival to improve islet transplantation outcome in diabetes treatment. J Nanobiotechnology. 2024;22:792. doi:10.1186/s12951-024-03072-5

We explored a cutting-edge peptide hydrogel designed to improve islet transplantation outcomes for diabetes. By integrating glucagon-like peptide-1 (GLP-1) into a self-assembling nanofiber structure, we aimed to address the common issues of islet graft survival and function.

In our tests, this innovative hydrogel notably increased islet function and longevity, reducing inflammation and enhancing metabolic control in a mouse model. The findings show promise for localized delivery methods and suggest a potential breakthrough in diabetes treatment through improved graft efficacy.

Promotes hair growth

Most Useful Review

4 people found this helpful

My mother has type 2 diabetes and since taking biotin, her hair loss has decreased significantly. After starting biotin alongside her ketogenic diet, she noticed new hair growth. She plans to continue purchasing this product as it has been effective for her hair and glucose levels.

Updated: Mar 2026

Food Poisoning details

Accelerates metabolism

4 people found this helpful

This product promotes hair and nail growth while accelerating metabolism. It has shown significant improvement in hair growth and nail strength within 30 days. However, those with health concerns should consult their doctor before use.

Hypothyroidism details

Low-dose biotin effects minimal

Questionable

Based on 2 Researches

Angelopoulos N, Paparodis RD, Androulakis I, Anagnostis P, Boniakos A, et al. The clinical significance of low dose biotin supplements (<300μg/day) in the treatment of patients with hypothyroidism: crucial or overestimated?. Thyroid Res. 2023;16:18. doi:10.1186/s13044-023-00162-8

We set out to investigate how low-dose biotin supplements, specifically those containing less than 300μg per day, might affect thyroid hormone levels in patients with hypothyroidism. Our approach included a detailed evaluation of 57 patients who were receiving thyroxine and also taking biotin supplements for a period ranging from 10 to 60 days.

Throughout the study, we measured the levels of thyroid-stimulating hormone (TSH) and free T4 (FT4) while the patients were on biotin and again 10 days after they stopped taking the supplement. As a control, we compared these findings to those of 31 age-matched individuals who were also being treated for hypothyroidism but were not using biotin.

Our analysis suggests that any changes observed in thyroid hormone profiles due to low-dose biotin supplementation are not clinically significant. In most cases, these changes do not warrant any adjustments to the patient's thyroid medication.

Overall, while our findings contribute to understanding the relationship between biotin and thyroid hormone levels, it appears that low-dose biotin may not play a crucial role in the treatment of hypothyroidism. Larger, more comprehensive studies would be beneficial to explore this phenomenon further.

7.5

Stopped hair fall

Most Useful Review

5 people found this helpful

I began using biotin as part of a comprehensive regimen to combat hair loss linked to hypothyroidism. After about three months, my hair stopped falling drastically, and the quality improved. I carefully selected my supplements, ensuring I addressed all nutrient needs to see these positive results.

Updated: Mar 2026

Sleep Apnea details

Natural sleep solution

1 people found this helpful

I can now sleep well after switching from commercial sleep inducers, which caused headaches and fatigue. Melatonin offers a more natural sleep. I recommend it to anyone facing similar issues.

539 people found this helpful

Attention Deficit Hyperactivity Disorder details

Excellent! I order almost all vitamin complexes from IHerb, as the prices are significantly lower than in local pharmacies with guaranteed quality. Since taking Biotin, my hair has become lively and shiny. Additionally, the pills have completely halted my hair loss! However, my nails do grow quickly, requiring more frequent gel polish applications. I drink biotin annually, and my hair feels thicker.

Eczema details

Biotin treatment for eczema effectiveness

Based on 5 Researches

Yang Y, Yang JY, Chen XJ. Biotinidase deficiency characterized by skin and hair findings. Clin Dermatol. 2020;38:477. doi:10.1016/j.clindermatol.2020.03.004

We explored a unique case involving a girl diagnosed with biotinidase deficiency, a rare inherited metabolic condition that can lead to notable skin and hair issues. The report highlighted her struggles with intractable dermatitis, yellow hair, and alopecia—symptoms that pointed to the underlying deficiency.

Biotin, a vital nutrient, was administered at a dose of 20 mg per day as a replacement therapy. Within one month, we observed a substantial improvement in her dermatitis, and by the three-month mark, her hair color had returned to near normal. The significant change in her condition illustrates how effective biotin can be for individuals suffering from both biotinidase deficiency and associated eczema-like symptoms.

This case serves as a reminder for healthcare providers, especially dermatologists, to consider biotinidase deficiency as a potential factor when treating similar conditions in children. By recognizing the importance of biotin, we can help improve health outcomes for those experiencing dermatological challenges tied to this rare disorder.

Eczema improvement

Most Useful Review

21 people found this helpful

My dog had skin issues, and after using biotin, his eczema improved significantly. I stopped giving it for a while, but the eczema returned. Biotin is now a staple in his routine.

Updated: Mar 2026

Psoriasis details

10 people found this helpful

I have suffered from psoriasis vulgaris and have been taking biotin for some time. With three tablets daily, I’ve healed from within and feel that my hair and nails grow rapidly.

Rash details

Biotin effectively improves rash symptoms

Based on 16 Researches

Kim SW, Lee HJ, Choi N, Kim EK, Ko JM. Dramatic Clinical Improvement With Biotin Mega-Dose Therapy in a Neonate With Holocarboxylase Synthetase Deficiency. Mol Genet Genomic Med. 2024;12:e70002. doi:10.1002/mgg3.70002

We explored the effects of biotin therapy on a neonate suffering from a rare metabolic disorder known as holocarboxylase synthetase deficiency. After initiating a biotin mega-dose regimen, we observed impressive results, with the baby showing notable clinical improvement just one day later.

Within six days, mechanical ventilation was no longer necessary, and the child maintained stable health through follow-ups. This case underscores the importance of early genetic testing and how effective biotin can be in treating specific metabolic issues.

No rashes experienced

Most Useful Review

45 people found this helpful

I take this biotin in courses, and the effect was immediate; my hair became more manageable and my skin smooth without rashes. I highly recommend buying it! If you appreciate this review, please support it with a like!

Updated: Mar 2026

Yeast Infection details

I bought this product to combat hair loss but haven't noticed any changes. My yeast infection remains unresolved, and I've seen no improvement in my hair condition.

Abscess details

Biotin impacts abscess resolution

Based on 2 Researches

Chetan C, Singh B, Patra S, Gupta G. Biotinidase deficiency-masquerade of primary immunodeficiency disease in neonate. BMJ Case Rep. 2024;17. doi:10.1136/bcr-2023-258833

We explored the effects of biotin supplementation in a neonate with biotinidase deficiency who presented with severe symptoms. The case involved multiple abscesses, seizures, and septic arthritis, leading to concerns about primary immunodeficiency. After diagnosis, we initiated biotin treatment, which resulted in no further severe infections, seizures, or skin issues.

This highlights the importance of early detection and treatment of biotinidase deficiency and its relation to abscess formation.

Effective for eczema

Most Useful Review

7 people found this helpful

Housewife's eczema, which I suffered from, was painful and spread upon scratching. Despite visiting several dermatologists, I only saw minimal improvement with steroid ointments. After researching online, I tried biotin. After a while, my condition returned to normal. I continue to take biotin regularly.

Updated: Mar 2026

Chronic Cough details

3 people found this helpful

Very satisfied! As I often touch water at work, I suffered from chronic hand roughness and weak nails, often resulting in doubled nails and breakage. After beginning biotin, I noticed improvement in my hands' textures within a week and a significant decrease in nail issues after three weeks. My nails are now much stronger than before!

Excellent! Biotin in this dosage helps me with bile reflux. I take it in the morning with breakfast. Good therapeutic dosage, and the package lasts a long time.

Reflux details

Chromium and biotin affect diabetes

High Cholesterol details

Albarracin C, Fuqua B, Geohas J, Juturu V, Finch MR, et al. Combination of chromium and biotin improves coronary risk factors in hypercholesterolemic type 2 diabetes mellitus: a placebo-controlled, double-blind randomized clinical trial. J Cardiometab Syndr. 2007;2:91.

We investigated the effects of a combination of chromium and biotin on cholesterol levels in people with type 2 diabetes. In a randomized, double-blind trial with 348 participants, those taking the supplement showed improvements in blood sugar levels and cholesterol levels compared to the placebo group.

However, while the chromium and biotin combination did yield positive results for cholesterol in some participants, overall, we found no significant changes in lipid levels for all participants. This suggests that while chromium and biotin may help with metabolic factors, their direct impact on cholesterol may be limited.

Successful hair regrowth

Most Useful Review

6 people found this helpful

Miracle biotin! I struggled with hair loss for a long time and tried everything, but only biotin worked. I developed a routine of taking half a tablet, which successfully stopped my hair loss and significantly increased hair growth. I am thrilled with the results!

Updated: Mar 2026

Hives details

Excellent! My husband suffered from hives, and despite steroid treatment, nothing worked. After reading a review, we decided to daily take biotin, and it nearly completely healed his hives. I keep purchasing this product.

1 people found this helpful

Pelvic Pain details

Chronic back pain made my life miserable until I discovered biotin in 2012. Now, my pain has dramatically reduced, allowing me to stand longer and engage more actively in life. Additionally, my energy levels have significantly improved.

10 people found this helpful

Nausea details

This supplement, prescribed by my doctor, has been a useful aid for hair growth. By the end of the month, I noticed less hair falling out and improved hair quality. The tablets are small, easy to consume, and have no smell or taste. I experienced no nausea or allergic reactions, and I am very pleased with the effects.

Adenoiditis details

Hair density restored

3 people found this helpful

I would recommend this product to anyone! While taking antibiotics, my hair was coming out in handfuls when washing, and my throat felt very sore. After five days, hair loss decreased by 70%, returning to a normal shedding rate of 7-9 hairs per wash after two weeks. I take half a tablet once daily, which lasts me six months! I now hope to restore my hair density more quickly with biotin. I advise everyone to try it.

Swollen Lymph Nodes details

Inflammation reduction

I take biotin with Acidophilus three times a day to alleviate atopic dermatitis symptoms. I've noticed that it effectively suppresses swelling inflammation and has improved the smoothness of my skin, even in areas without atopic symptoms.

Allergies details

Biotin's impact on allergies explored

Based on 3 Researches

Kuroishi T. Regulation of immunological and inflammatory functions by biotin. Can J Physiol Pharmacol. 2015;93:1091. doi:10.1139/cjpp-2014-0460

We investigated the effects of biotin on immune responses and inflammatory conditions. Biotin, a necessary vitamin, plays a role in various metabolic pathways related to inflammation. While previous studies have suggested that biotin deficiency can lead to skin inflammation and immune issues, our findings highlight the potential of biotin supplementation in addressing metal allergies in animal models. However, significant improvements in allergy symptoms were not conclusively shown. Thus, while biotin may be beneficial, more research is needed to fully understand its impact on allergies.

7.5

Reduced nasal allergy

Most Useful Review

82 people found this helpful

I noticed a positive effect after purchasing this for my allergies. For years I used Allegra but stopped taking it and found improvement in my severe nasal allergy symptoms.

Updated: Mar 2026

Autoimmune Disorder details